Loading Icon

Pyruvate kinase

Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP), yielding one molecule of pyruvate and one molecule of ATP. Pyruvate kinase was inappropriately named (inconsistently with a conventional kinase) before it was recognized that it did not directly catalyze phosphorylation of pyruvate, which does not occur under physiological conditions. Pyruvate kinase is present in four distinct, tissue-specific isozymes in animals, each consisting of particular kinetic properties necessary to accommodate the variations in metabolic requirements of diverse tissues.

Metrics Summary

Total Publications
Lifetime
4,115
Prior Five Years
539
Total Citations
Lifetime
81,350
Prior Five Years
6,110
Total Scholars
Lifetime
7,470
Prior Five Years
5,143

Institutional Rankings

Global (Worldwide)
Show More
National Institutional Rankings

Publications and Citation History

Publications based on Disciplines

Scholars based on Disciplines

Publications based on Fields

Scholars based on Fields

Highly Ranked Scholars™

Lifetime
Prior Five Years

Highly Cited Publications

Lifetime