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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group. This process and its inverse, dephosphorylation, are critical for many cellular processes in biology. Protein phosphorylation is especially important for their function; for example, this modification activates (or deactivates) almost half of the enzymes present in Saccharomyces cerevisiae, thereby regulating their function. Many proteins (between 1/3 to 2/3 of the proteome in eukaryotes) are phosphorylated temporarily, as are many sugars, lipids, and other biologically-relevant molecules.

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67,491
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