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Immortalised cell line

An immortalised cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes. Immortal cell lines are a very important tool for research into the biochemistry and cell biology of multicellular organisms. Immortalised cell lines have also found uses in biotechnology.

Metrics Summary

Total Publications
Lifetime
117,512
Prior Five Years
16,402
Total Citations
Lifetime
2,386,616
Prior Five Years
116,549
Total Scholars
Lifetime
246,719
Prior Five Years
171,359

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