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Knockout mouse

A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. They are important animal models for studying the role of genes which have been sequenced but whose functions have not been determined. By causing a specific gene to be inactive in the mouse, and observing any differences from normal behaviour or physiology, researchers can infer its probable function.

Metrics Summary

Total Publications
Lifetime
11,719
Prior Five Years
1,858
Total Citations
Lifetime
377,435
Prior Five Years
14,322
Total Scholars
Lifetime
38,585
Prior Five Years
30,123

Institutional Rankings

Global (Worldwide)
Academic Institutions
Lifetime
Academic Institutions
Prior Five Years
Non-academic Institutions
Lifetime
#1
United States
#1
United States
#1
France
#2
United States
#2
China
#2
United States
#3
Japan
#3
United Kingdom
#3
United States
#4
United States
#4
United States
#4
United States
#5
Netherlands
#5
United States
#5
United States
#6
United States
#6
United States
#6
Australia
#7
United States
#7
China
#7
Japan
#8
Spain
#8
United States
#8
United States
#9
United States
#9
United States
#9
United States
#10
Belgium
#10
Germany
#10
Japan
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National Institutional Rankings

Publications and Citation History

Publications based on Disciplines

Scholars based on Disciplines

Publications based on Fields

Scholars based on Fields

Highly Ranked Scholars™

Lifetime
Prior Five Years

Highly Cited Publications

Lifetime