Jay Gopalakrishnan

ScholarGPS® ID: 99575466746464

Affiliation

Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Affiliation History

Field

Life Sciences

Discipline

Genetics

Top Specialties

Cancer | Stem Cell | Cancer Cell | Drosophila | Mitosis

Metrics Summary

Publication Count

Predicted Citations

2,292

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Pervasive structural heterogeneity rewires glioblastoma chromosomes to sustain patient-specific transcriptional programs (journal article) Xie, Ting \| Danieli-Mackay, Adi \| Buccarelli, Mariachiara \| Barbieri, Mariano \| Papadionysiou, Ioanna \| D’Alessandris, Q. Giorgio \| Robens, Claudia \| Übelmesser, Nadine \| Vinchure, Omkar Suhas \| Lauretti, Liverana \| ... \| Papantonis, Argyris Nature Communications, volume 15, issue 1 (2024). 10.1038/s41467-024-48053-2 Cite \| Source
Inhibiting centrosome clustering reduces cystogenesis and improves kidney function in autosomal dominant polycystic kidney disease (journal article) Cheng, Tao \| Mariappan, Aruljothi \| Langner, Ewa \| Shim, Kyuhwan \| Gopalakrishnan, Jay \| Mahjoub, Moe R. JCI Insight, volume 9, issue 4 (2024). 10.1172/jci.insight.172047 Cited by (1) \| Cite \| Source
Emerging principles of primary cilia dynamics in controlling tissue organization and function (journal article) Gopalakrishnan, Jay \| Feistel, Kerstin \| Friedrich, Benjamin M \| Grapin‐Botton, Anne \| Jurisch‐Yaksi, Nathalie \| Mass, Elvira \| Mick, David U \| Müller, Roman‐Ulrich \| May‐Simera, Helen \| Schermer, Bernhard \| ... \| Wachten, Dagmar The EMBO Journal, volume 42, issue 21 (2023). 10.15252/embj.2023113891 Cited by (3) \| Cite \| Source
DNA damage and repair: underlying mechanisms leading to microcephaly (journal article) Ribeiro, Jessica Honorato \| Altinisik, Nazlican \| Rajan, Nicholas \| Verslegers, Mieke \| Baatout, Sarah \| Gopalakrishnan, Jay \| Quintens, Roel Frontiers in Cell and Developmental Biology, volume 11 (2023). 10.3389/fcell.2023.1268565 Cited by (3) \| Cite \| Source
Generation of iPSC-derived human forebrain organoids assembling bilateral eye primordia (journal article) Gabriel, Elke \| Albanna, Walid \| Pasquini, Giovanni \| Ramani, Anand \| Josipovic, Natasa \| Mariappan, Aruljothi \| Riparbelli, Maria Giovanna \| Callaini, Giuliano \| Karch, Celeste M. \| Goureau, Olivier \| ... \| Gopalakrishnan, Jay Nature Protocols, volume 18, issue 6, pages 1893-1929 (2023). 10.1038/s41596-023-00814-x Cited by (4) \| Cite \| Source
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2 (journal article) Bieder, Andrea \| Chandrasekar, Gayathri \| Wason, Arpit \| Erkelenz, Steffen \| Gopalakrishnan, Jay \| Kere, Juha \| Tapia-Páez, Isabel BMC Molecular and Cell Biology, volume 24, issue 1 (2023). 10.1186/s12860-023-00483-4 Cited by (1) \| Cite \| Source
Exome sequencing and functional analyses revealed CETN1 variants leads to impaired cell division and male fertility (journal article) Sudhakar, Digumarthi V S \| Phanindranath, Regur \| Jaishankar, Shveta \| Ramani, Anand \| Kalamkar, Kaustubh P \| Kumar, Umesh \| Pawar, Asmita D \| Dada, Rima \| Singh, Rajender \| Gupta, Nalini J \| ... \| Thangaraj, Kumarasamy Human Molecular Genetics, volume 32, issue 4, pages 533-542 (2023). 10.1093/hmg/ddac216 Cited by (3) \| Cite \| Source
Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling (journal article) Lee, Derrick \| Gimple, Ryan C. \| Wu, Xujia \| Prager, Briana C. \| Qiu, Zhixin \| Wu, Qiulian \| Daggubati, Vikas \| Mariappan, Aruljothi \| Gopalakrishnan, Jay \| Sarkisian, Matthew R. \| ... \| Rich, Jeremy N. Journal of Clinical Investigation, volume 133, issue 2 (2023). 10.1172/JCI163592 Cited by (8) \| Cite \| Source
Brain Organoid Research (book) Springer US (2023) 10.1007/978-1-0716-2720-4 Cited by (3) \| Cite \| Source
A Three-Dimensional Organoid Culture System to Model Invasive Patterns of Patient-Derived Glioma Stem Cells (book chapter) In Brain Organoid Research Mariappan, Aruljothi \| Knauth, Theda \| Pallini, Roberto \| Gopalakrishnan, Jay Springer US (2023) 10.1007/978-1-0716-2720-4_8 Cite \| Source
Infection of 3D Brain Organoids with Human Pathogenic Viruses Under Biosafety Level-3 Conditions with Subsequent Inactivation to Study Viral Replication, Pathomechanisms, and Other Viral Infection-Mediated Effects (book chapter) In Brain Organoid Research Ostermann, Philipp Niklas \| Ramani, Anand \| Bergmann, Ann Kathrin \| Adams, Ortwin \| Gopalakrishnan, Jay \| Schaal, Heiner Springer US (2023) 10.1007/978-1-0716-2720-4_11 Cited by (1) \| Cite \| Source
Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids (journal article) Chandrasegaran, Praveena \| Nabilla Lestari, Agatha \| Sinton, Matthew C. \| Gopalakrishnan, Jay \| Quintana, Juan F. F1000Research, volume 12 (2023). 10.12688/f1000research.131507.1 Cite \| Source
Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids (journal article) Chandrasegaran, Praveena \| Nabilla Lestari, Agatha \| Sinton, Matthew C. \| Gopalakrishnan, Jay \| Quintana, Juan F. F1000Research, volume 12 (2023). 10.12688/f1000research.131507.2 Cited by (1) \| Cite \| Source
Development and Validation of a HPLC–MS/MS Method to Measure Nifuroxazide and Its Application in Healthy and Glioblastoma-Bearing Mice (journal article) Ceruti, Tommaso \| D’Alessandris, Quintino Giorgio \| Frapolli, Roberta \| Gopalakrishnan, Jay \| Buccarelli, Mariachiara \| Meroni, Marina \| Lauretti, Liverana \| Ricci-Vitiani, Lucia \| Pallini, Roberto \| Zucchetti, Massimo Pharmaceutics, volume 14, issue 10, pages 2071- (2022). 10.3390/pharmaceutics14102071 Cited by (2) \| Cite \| Source
Hirnorganoide entwickeln von Natur aus Augenprimordien (journal article) Gabriel, Elke \| Fenner, Maria \| Gopalakrishnan, Jay BIOspektrum, volume 28, issue 5, pages 497-500 (2022). 10.1007/s12268-022-1817-3 Cite \| Source
B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner (journal article) Stein, Andreas \| Hilken née Thomopoulou, Persefoni \| Frias, Corazon \| Hopff, Sina M. \| Varela, Paloma \| Wilke, Nicola \| Mariappan, Arul \| Neudörfl, Jörg-Martin \| Fedorov, Alexey Yu \| Gopalakrishnan, Jay \| ... \| Schmalz, Hans-Günther ACS Omega, volume 7, issue 3, pages 2591-2603 (2022). 10.1021/acsomega.1c04659 Cited by (6) \| Cite \| Source
Human brain organoids assemble functionally integrated bilateral optic vesicles (journal article) Gabriel, Elke \| Albanna, Walid \| Pasquini, Giovanni \| Ramani, Anand \| Josipovic, Natasa \| Mariappan, Aruljothi \| Schinzel, Friedrich \| Karch, Celeste M. \| Bao, Guobin \| Gottardo, Marco \| ... \| Gopalakrishnan, Jay Cell Stem Cell, volume 28, issue 10, pages 1740-1757.e8 (2021). 10.1016/j.stem.2021.07.010 Cited by (85) \| Cite \| Source
Neurotropic Effects of SARS-CoV-2 Modeled by the Human Brain Organoids (journal article) Ramani, Anand \| Pranty, Abida-Islam \| Gopalakrishnan, Jay Stem Cell Reports, volume 16, issue 3, pages 373-384 (2021). 10.1016/j.stemcr.2021.02.007 Cited by (38) \| Cite \| Source
Trends and challenges in modeling glioma using 3D human brain organoids (journal article) Mariappan, Aruljothi \| Goranci-Buzhala, Gladiola \| Ricci-Vitiani, Lucia \| Pallini, Roberto \| Gopalakrishnan, Jay Cell Death & Differentiation, volume 28, issue 1, pages 15-23 (2021). 10.1038/s41418-020-00679-7 Cited by (30) \| Cite \| Source
Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications (journal article) Liu, Wei \| Stachura, Paweł \| Xu, Haifeng C. \| Umesh Ganesh, Nikkitha \| Cox, Fiona \| Wang, Ruifeng \| Lang, Karl S. \| Gopalakrishnan, Jay \| Häussinger, Dieter \| Homey, Bernhard \| ... \| Pandyra, Aleksandra A. Journal of Experimental & Clinical Cancer Research, volume 39, issue 1 (2020). 10.1186/s13046-020-1539-7 Cited by (18) \| Cite \| Source