Frank J. Bruggeman

ScholarGPS® ID: 98661216986365

Affiliation

Vrije Universiteit Amsterdam, Amsterdam, Netherlands

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Metrics Summary

Publication Count

133

Predicted Citations

7,981

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Understanding and computational design of genetic circuits of metabolic networks (journal article) Berkvens, Alicia \| Salinas, Luis \| Remeijer, Maaike \| Planqué, Robert \| Teusink, Bas \| Bruggeman, Frank J. Essays in Biochemistry, volume 68, issue 1, pages 41-51 (2024). 10.1042/EBC20230045 Cited by (1) \| Cite \| Source
Whole-cell metabolic control analysis (journal article) Bruggeman, Frank J. \| Remeijer, Maaike \| Droste, Maarten \| Salinas, Luis \| Wortel, Meike \| Planqué, Robert \| Sauro, Herbert M. \| Teusink, Bas \| Westerhoff, Hans V. Biosystems, volume 234 (2023). 10.1016/j.biosystems.2023.105067 Cited by (1) \| Cite \| Source
Understanding spatiotemporal coupling of gene expression using single molecule RNA imaging technologies (journal article) Gerber, Alan \| van Otterdijk, Sander \| Bruggeman, Frank J. \| Tutucci, Evelina Transcription, volume 14, issue 3-5, pages 105-126 (2023). 10.1080/21541264.2023.2199669 Cited by (2) \| Cite \| Source
Trade‐offs between the instantaneous growth rate and long‐term fitness: Consequences for microbial physiology and predictive computational models (journal article) Bruggeman, Frank J. \| Teusink, Bas \| Steuer, Ralf BioEssays, volume 45, issue 10 (2023). 10.1002/bies.202300015 Cited by (7) \| Cite \| Source
Is distance from equilibrium a good indicator for a reaction’s flux control? (journal article) van Niekerk, David D. \| Rust, Erik \| Bruggeman, Frank \| Westerhoff, Hans V. \| Snoep, Jacky L. Biosystems, volume 232 (2023). 10.1016/j.biosystems.2023.104988 Cited by (1) \| Cite \| Source
Effective bet-hedging through growth rate dependent stability (journal article) de Groot, Daan H. \| Tjalma, Age J. \| Bruggeman, Frank J. \| van Nimwegen, Erik Proceedings of the National Academy of Sciences, volume 120, issue 8 (2023). 10.1073/pnas.2211091120 Cited by (6) \| Cite \| Source
Escherichia coli robustly expresses ATP synthase at growth rate‐maximizing concentrations (journal article) Rabbers, Iraes \| Bruggeman, Frank J. The FEBS Journal, volume 289, issue 16, pages 4925-4934 (2022). 10.1111/febs.16401 Cited by (4) \| Cite \| Source
Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors (journal article) Chavez-Abiega, Sergei \| Grönloh, Max L. B. \| Gadella, Theodorus W. J. \| Bruggeman, Frank J. \| Goedhart, Joachim Journal of Cell Science, volume 135, issue 6 (2022). 10.1242/jcs.259685 Cited by (11) \| Cite \| Source
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies (journal article) Elsemman, Ibrahim E. \| Rodriguez Prado, Angelica \| Grigaitis, Pranas \| Garcia Albornoz, Manuel \| Harman, Victoria \| Holman, Stephen W. \| van Heerden, Johan \| Bruggeman, Frank J. \| Bisschops, Mark M. M. \| Sonnenschein, Nikolaus \| ... \| Teusink, Bas Nature Communications, volume 13, issue 1 (2022). 10.1038/s41467-022-28467-6 Cited by (40) \| Cite \| Source
Selection for Cell Yield Does Not Reduce Overflow Metabolism in Escherichia coli (journal article) Rabbers, Iraes \| Gottstein, Willi \| Feist, Adam M \| Teusink, Bas \| Bruggeman, Frank J \| Bachmann, Herwig Molecular Biology and Evolution, volume 39, issue 1 (2022). 10.1093/molbev/msab345 Cited by (3) \| Cite \| Source
A yeast FRET biosensor enlightens cAMP signaling (journal article) Botman, Dennis \| O’Toole, Tom G. \| Goedhart, Joachim \| Bruggeman, Frank J. \| van Heerden, Johan H. \| Teusink, Bas Molecular Biology of the Cell, volume 32, issue 13, pages 1229-1240 (2021). 10.1091/mbc.E20-05-0319 Cited by (11) \| Cite \| Source
The Fundamental Equations of Change in Statistical Ensembles and Biological Populations (journal article) Frank, Steven A. \| Bruggeman, Frank J. Entropy, volume 22, issue 12, pages 1395- (2020). 10.3390/e22121395 Cited by (7) \| Cite \| Source
Searching for principles of microbial physiology (journal article) Bruggeman, Frank J \| Planqué, Robert \| Molenaar, Douwe \| Teusink, Bas FEMS Microbiology Reviews, volume 44, issue 6, pages 821-844 (2020). 10.1093/femsre/fuaa034 Cited by (44) \| Cite \| Source
The omnistat: A flexible continuous‐culture system for prolonged experimental evolution (journal article) Ekkers, David M. \| Branco dos Santos, Filipe \| Mallon, Cyrus A. \| Bruggeman, Frank \| van Doorn, G. Sander Methods in Ecology and Evolution, volume 11, issue 8, pages 932-942 (2020). 10.1111/2041-210X.13403 Cited by (14) \| Cite \| Source
Biphasic Cell-Size and Growth-Rate Homeostasis by Single Bacillus subtilis Cells (journal article) Nordholt, Niclas \| van Heerden, Johan H. \| Bruggeman, Frank J. Current Biology, volume 30, issue 12, pages 2238-2247.e5 (2020). 10.1016/j.cub.2020.04.030 Cited by (22) \| Cite \| Source
The common message of constraint-based optimization approaches: overflow metabolism is caused by two growth-limiting constraints (journal article) de Groot, Daan H. \| Lischke, Julia \| Muolo, Riccardo \| Planqué, Robert \| Bruggeman, Frank J. \| Teusink, Bas Cellular and Molecular Life Sciences, volume 77, issue 3, pages 441-453 (2020). 10.1007/s00018-019-03380-2 Cited by (39) \| Cite \| Source
Elementary Growth Modes provide a molecular description of cellular self-fabrication (journal article) de Groot, Daan H. \| Hulshof, Josephus \| Teusink, Bas \| Bruggeman, Frank J. \| Planqué, Robert PLOS Computational Biology, volume 16, issue 1, pages e1007559- (2020). 10.1371/journal.pcbi.1007559 Cited by (19) \| Cite \| Source
Adaption to glucose limitation is modulated by the pleotropic regulator CcpA, independent of selection pressure strength (journal article) Price, Claire E. \| Branco dos Santos, Filipe \| Hesseling, Anne \| Uusitalo, Jaakko J. \| Bachmann, Herwig \| Benavente, Vera \| Goel, Anisha \| Berkhout, Jan \| Bruggeman, Frank J. \| Marrink, Siewert-Jan \| ... \| Kuipers, Oscar P. BMC Evolutionary Biology, volume 19, issue 1 (2019). 10.1186/s12862-018-1331-x Cited by (16) \| Cite \| Source
Physical biology of GPCR signalling dynamics inferred from fluorescence spectroscopy and imaging (journal article) Chavez-Abiega, Sergei \| Goedhart, Joachim \| Bruggeman, Frank Johannes Current Opinion in Structural Biology, volume 55 (2019). 10.1016/j.sbi.2019.05.007 Cited by (9) \| Cite \| Source
The number of active metabolic pathways is bounded by the number of cellular constraints at maximal metabolic rates (journal article) de Groot, Daan H. \| van Boxtel, Coco \| Planqué, Robert \| Bruggeman, Frank J. \| Teusink, Bas PLOS Computational Biology, volume 15, issue 3, pages e1006858- (2019). 10.1371/journal.pcbi.1006858 Cited by (24) \| Cite \| Source