G. Paolo Dotto

ScholarGPS® ID: 98638465693220

Affiliation

University of Lausanne, Lausanne,Chavannes-près-Renens,Écublens,Saint-Sulpice andÉpalinges, Switzerland

Affiliation History

Field

Life Sciences

Discipline

Biochemistry

Top Specialties

Metrics Summary

Publication Count

154

Predicted Citations

16,053

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation (journal article) Mazzeo, Luigi \| Ghosh, Soumitra \| Di Cicco, Emery \| Isma, Jovan \| Tavernari, Daniele \| Samarkina, Anastasia \| Ostano, Paola \| Youssef, Markus K. \| Simon, Christian \| Dotto, G. Paolo Nature Communications, volume 15, issue 1 (2024). 10.1038/s41467-024-45308-w Cited by (2) \| Cite \| Source
Androgen receptor is a determinant of melanoma targeted drug resistance (journal article) Samarkina, Anastasia \| Youssef, Markus Kirolos \| Ostano, Paola \| Ghosh, Soumitra \| Ma, Min \| Tassone, Beatrice \| Proust, Tatiana \| Chiorino, Giovanna \| Levesque, Mitchell P. \| Goruppi, Sandro \| Dotto, Gian Paolo Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-42239-w Cited by (8) \| Cite \| Source
HSD17B7 gene in self‐renewal and oncogenicity of keratinocytes from Black versus White populations (journal article) Xu, Xiaoying \| Tassone, Beatrice \| Ostano, Paola \| Katarkar, Atul \| Proust, Tatiana \| Joseph, Jean‐Marc \| Riganti, Chiara \| Chiorino, Giovanna \| Kutalik, Zoltan \| Lefort, Karine \| Dotto, Gian Paolo EMBO Molecular Medicine, volume 13, issue 7 (2021). 10.15252/emmm.202114133 Cited by (8) \| Cite \| Source
Flash forward genetics: new twists in transcription across evolutionary boundaries (journal article) Dotto, G Paolo \| Missero, Caterina EMBO reports, volume 22, issue 3 (2021). 10.15252/embr.202052152 Cite \| Source
Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis (journal article) Ma, Min \| Ghosh, Soumitra \| Tavernari, Daniele \| Katarkar, Atul \| Clocchiatti, Andrea \| Mazzeo, Luigi \| Samarkina, Anastasia \| Epiney, Justine \| Yu, Yi-Ru \| Ho, Ping-Chih \| ... \| Dotto, G. Paolo Journal of Experimental Medicine, volume 218, issue 2 (2021). 10.1084/jem.20201137 Cited by (27) \| Cite \| Source
Phenformin Promotes Keratinocyte Differentiation via the Calcineurin/NFAT Pathway (journal article) Zhou, Qian \| Kim, Sun Hye \| Pérez-Lorenzo, Rolando \| Liu, Chang \| Huang, Man \| Dotto, Gian Paolo \| Zheng, Bin \| Wu, Xunwei Journal of Investigative Dermatology, volume 141, issue 1, pages 152-163 (2021). 10.1016/j.jid.2020.05.114 Cited by (12) \| Cite \| Source
Visualizing cellular heterogeneity by quantifying the dynamics of MAPK activity in live mammalian cells with synthetic fluorescent biosensors (journal article) Ma, Min \| Bordignon, Pino \| Dotto, Gian-Paolo \| Pelet, Serge Heliyon, volume 6, issue 12, pages e05574- (2020). 10.1016/j.heliyon.2020.e05574 Cited by (7) \| Cite \| Source
NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin (journal article) Katarkar, Atul \| Bottoni, Giulia \| Clocchiatti, Andrea \| Goruppi, Sandro \| Bordignon, Pino \| Lazzaroni, Francesca \| Gregnanin, Ilaria \| Ostano, Paola \| Neel, Victor \| Dotto, G. Paolo Nature Communications, volume 11, issue 1 (2020). 10.1038/s41467-020-18919-2 Cited by (24) \| Cite \| Source
Response by the author (journal article) Dotto, Gian Paolo EMBO reports, volume 21, issue 10 (2020). 10.15252/embr.202051505 Cite \| Source
Conjectures, refutations and the search for truths (journal article) Dotto, G Paolo EMBO reports, volume 21, issue 2 (2020). 10.15252/embr.201949924 Cite \| Source
Sex Hormones and Anticancer Immunity (journal article) Özdemir, Berna C. \| Dotto, Gian-Paolo Clinical Cancer Research, volume 25, issue 15, pages 4603-4610 (2019). 10.1158/1078-0432.CCR-19-0137 Cited by (84) \| Cite \| Source
Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant (journal article) Bordignon, Pino \| Bottoni, Giulia \| Xu, Xiaoying \| Popescu, Alma S. \| Truan, Zinnia \| Guenova, Emmanuella \| Kofler, Lukas \| Jafari, Paris \| Ostano, Paola \| Röcken, Martin \| ... \| Dotto, G. Paolo Cell Reports, volume 28, issue 9, pages 2358-2372.e6 (2019). 10.1016/j.celrep.2019.07.092 Cited by (72) \| Cite \| Source
Photodynamic priming and VDR activation modulate tumor-stroma interactions and permeability for durable control and enhanced treatment tolerability (Conference Presentation) (conference) Pigula, Michael \| Anbil, Sriram \| Huang, Huang-Chiao \| Baglo, Yan \| Broekgaarden, Mans \| Simeone, Diane \| Dotto, Gian Paolo \| Hasan, Tayyaba 17th International Photodynamic Association World Congress (2019) Cambridge, United States 10.1117/12.2526104 Cite \| Source
Retraction Notice to: RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress (journal article) Ongusaha, Pat P. \| Kim, Hyung-Gu \| Boswell, Sarah A. \| Ridley, Anne J. \| Der, Channing J. \| Dotto, G. Paolo \| Kim, Young-Bum \| Aaronson, Stuart A. \| Lee, Sam W. Current Biology, volume 29, issue 12, pages 2107- (2019). 10.1016/j.cub.2019.05.065 Cite \| Source
A role for stromal autophagy in cancer-associated fibroblast activation (journal article) Goruppi, Sandro \| Clocchiatti, Andrea \| Dotto, G. Paolo Autophagy (2019). 10.1080/15548627.2019.1569936 Cited by (17) \| Cite \| Source
Methods and compositions for the treatment of cancer (patent) Dotto, Gian Paolo \| Brooks, Yang Sui Patent Number: 10188747 (2019) Cite \| Source
Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation (journal article) Clocchiatti, Andrea \| Ghosh, Soumitra \| Procopio, Maria-Giuseppina \| Mazzeo, Luigi \| Bordignon, Pino \| Ostano, Paola \| Goruppi, Sandro \| Bottoni, Giulia \| Katarkar, Atul \| Levesque, Mitchell \| ... \| Dotto, G. Paolo Journal of Clinical Investigation, volume 128, issue 12, pages 5531-5548 (2018). 10.1172/JCI99159 Cited by (40) \| Cite \| Source
Sex Differences in Efficacy and Toxicity of Systemic Treatments: An Undervalued Issue in the Era of Precision Oncology (journal article) Özdemir, Berna C. \| Csajka, Chantal \| Dotto, Gian-Paolo \| Wagner, Anna Dorothea Journal of Clinical Oncology, volume 36, issue 26, pages 2680-2683 (2018). 10.1200/JCO.2018.78.3290 Cited by (103) \| Cite \| Source
Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism (journal article) Goruppi, Sandro \| Jo, Seung-Hee \| Laszlo, Csaba \| Clocchiatti, Andrea \| Neel, Victor \| Dotto, G. Paolo Cell Reports, volume 24, issue 12, pages 3108-3114.e4 (2018). 10.1016/j.celrep.2018.08.043 Cited by (19) \| Cite \| Source \| Open Access
Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B (journal article) Al Labban, Dania \| Jo, Seung-Hee \| Ostano, Paola \| Saglietti, Chiara \| Bongiovanni, Massimo \| Panizzon, Renato \| Dotto, G. Paolo Journal of Clinical Investigation, volume 128, issue 6, pages 2581-2599 (2018). 10.1172/JCI96915 Cited by (24) \| Cite \| Source \| Open Access

Title	Investigators	Year	Cost	Agency
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2020	$364,342	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2019	$364,342	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2018	$364,342	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Dermal fibroblast/ATF3 control of skin homeostasis	Dotto, Gian-Paolo	2018	$376,620	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2017	$364,342	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Dermal fibroblast/ATF3 control of skin homeostasis	Dotto, Gian-Paolo	2017	$376,620	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2016	$453,943	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Dermal fibroblast/ATF3 control of skin homeostasis	Dotto, Gian-Paolo	2016	$376,620	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Dermal fibroblast/ATF3 control of skin homeostasis	Dotto, Gian-Paolo	2015	$376,620	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2015	$453,943	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Dermal fibroblast/ATF3 control of skin homeostasis	Dotto, Gian-Paolo	2014	$376,620	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2014	$444,866	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2013	$431,247	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2012	$454,596	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Calcineurin signaling in the keratinocyte UVB response	Dotto, Gian-Paolo	2011	$342,543	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2011	$540,448	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Calcineurin signaling in the keratinocyte UVB response	Dotto, Gian-Paolo	2010	$356,816	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2010	$545,543	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Calcineurin signaling in the keratinocyte UVB response	Dotto, Gian-Paolo	2009	$360,420	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2009	$534,640	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Calcineurin signaling in the keratinocyte UVB response	Dotto, Gian-Paolo	2008	$360,420	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2008	$531,241	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Calcineurin signaling in the keratinocyte UVB response	Dotto, Gian-Paolo	2007	$367,775	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2007	$526,288	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Cellular and genetic control of keratinocyte development	Dotto, Gian-Paolo	2007	$308,386	NATIONAL CANCER INSTITUTE
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2006	$479,948	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Cellular and genetic control of keratinocyte development	Dotto, Gian-Paolo	2006	$317,597	NATIONAL CANCER INSTITUTE
Kinases and epithelial differentiation control	Dotto, Gian-Paolo	2006	$237,290	NATIONAL CANCER INSTITUTE
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2005	$491,499	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Cellular and genetic control of keratinocyte development	Dotto, Gian-Paolo	2005	$325,240	NATIONAL CANCER INSTITUTE
Kinases and epithelial differentiation control	Dotto, Gian-Paolo	2005	$243,000	NATIONAL CANCER INSTITUTE
Kinases and epithelial differentiation control	Dotto, Gian-Paolo	2004	$243,000	NATIONAL CANCER INSTITUTE
Growth differentiation control in primary keratinocytes	Dotto, Gian-Paolo	2004	$519,114	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Cellular and genetic control of keratinocyte development	Dotto, Gian-Paolo	2004	$325,240	NATIONAL CANCER INSTITUTE
Cellular and genetic control of keratinocyte development	Dotto, Gian Paolo	2003	$480,600	NATIONAL CANCER INSTITUTE
Growth differentiation control in primary keratinocytes	Dotto, Gian Paolo	2003	$346,114	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
THE SKIN AND ITS CELLS	Dotto, Gian Paolo	2003	$4,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Growth differentiation control in primary keratinocytes	Dotto, Gian Paolo	2003	$173,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	2002	$62,016	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
THE SKIN AND ITS CELLS	Dotto, Gian Paolo	2002	$4,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Kinases and epithelial differentiation control	Dotto, Gian Paolo	2002	$243,000	NATIONAL CANCER INSTITUTE
Kinases and epithelial differentiation control	Dotto, Gian Paolo	2002	$372,464	NATIONAL CANCER INSTITUTE
Growth differentiation control in primary keratinocytes	Dotto, Gian Paolo	2002	$346,114	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	2001	$103,906	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
THE SKIN AND ITS CELLS	Dotto, Gian Paolo	2001	$4,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
CELLULAR &GENETIC CONTROL OF KERATINOCYTE DEVELOPMENT	Dotto, Gian Paolo	2001	$256,266	NATIONAL CANCER INSTITUTE
KINASES AND EPITHELIAL DIFFERENTIATION CONTROL	Dotto, Gian Paolo	2001	$346,807	NATIONAL CANCER INSTITUTE
THE SKIN AND ITS CELLS	Dotto, Gian Paolo	2000	$4,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
KINASES AND EPITHELIAL DIFFERENTIATION CONTROL	Dotto, Gian Paolo	2000	$336,707	NATIONAL CANCER INSTITUTE
CELLULAR &GENETIC CONTROL OF KERATINOCYTE DEVELOPMENT	Dotto, Gian Paolo	2000	$248,846	NATIONAL CANCER INSTITUTE
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	2000	$249,537	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
WORKSHOP--THE SKIN AND ITS CELLS	Dotto, Gian Paolo	1999	$4,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1999	$242,270	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
CELLULAR &GENETIC CONTROL OF KERATINOCYTE DEVELOPMENT	Dotto, Gian Paolo	1999	$241,643	NATIONAL CANCER INSTITUTE
KINASES AND EPITHELIAL DIFFERENTIATION CONTROL	Dotto, Gian Paolo	1999	$326,897	NATIONAL CANCER INSTITUTE
KINASES AND EPITHELIAL DIFFERENTIATION CONTROL	Dotto, Gian Paolo	1998	$335,128	NATIONAL CANCER INSTITUTE
CELLULAR &GENETIC CONTROL OF KERATINOCYTE DEVELOPMENT	Dotto, Gian Paolo	1998	$234,651	NATIONAL CANCER INSTITUTE
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1998	$235,213	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
CELLULAR &GENETIC CONTROL OF KERATINOCYTE DEVELOPMENT	Dotto, Gian Paolo	1997	$227,861	NATIONAL CANCER INSTITUTE
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1997	$228,362	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1996	$210,234	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1995	$202,352	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
CELLULAR &GENETIC CONTROL OF KERATINOCYTE TUMORS	Dotto, Gian Paolo	1995	$174,414	NATIONAL CANCER INSTITUTE
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1994	$194,937	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
CELLULAR &GENETIC CONTROL OF KERATINOCYTE TUMORS	Dotto, Gian Paolo	1994	$164,351	NATIONAL CANCER INSTITUTE
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES.	Dotto, Gian Paolo	1993	$197,299	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
CELLULAR &GENETIC CONTROL OF KERATINOCYTE TUMORS	Dotto, Gian Paolo	1993	$160,668	NATIONAL CANCER INSTITUTE
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1992	$102,161	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1992	$55,852	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1992	$75,088	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1991	$49,150	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1990	$152,080	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1989	$149,409	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
GROWTH DIFFERENTIATION CONTROL IN PRIMARY KERATINOCYTES	Dotto, Gian Paolo	1988	$155,765	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES