Arianna Loregian

ScholarGPS® ID: 97956104385666

Affiliation

University of Padua, Padua, Italy

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Metrics Summary

Publication Count

117

Predicted Citations

4,446

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity (journal article) Desantis, Jenny \| Bazzacco, Alessandro \| Eleuteri, Michela \| Tuci, Sara \| Bianconi, Elisa \| Macchiarulo, Antonio \| Mercorelli, Beatrice \| Loregian, Arianna \| Goracci, Laura European Journal of Medicinal Chemistry, volume 268 (2024). 10.1016/j.ejmech.2024.116202 Cited by (2) \| Cite \| Source
Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus inhibitors (journal article) Trevisan, Marta \| Pianezzola, Anna \| Onorati, Marco \| Apolloni, Lorenzo \| Pistello, Mauro \| Arav-Boger, Ravit \| Palù, Giorgio \| Mercorelli, Beatrice \| Loregian, Arianna Antiviral Research, volume 223 (2024). 10.1016/j.antiviral.2024.105816 Cite \| Source
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5- a ]pyrimidines (journal article) Pacetti, Martina \| Pismataro, Maria Chiara \| Felicetti, Tommaso \| Giammarino, Federica \| Bonomini, Anna \| Tiecco, Matteo \| Bertagnin, Chiara \| Barreca, Maria Letizia \| Germani, Raimondo \| Cecchetti, Violetta \| ... \| Massari, Serena Organic & Biomolecular Chemistry, volume 22, issue 4, pages 767-783 (2024). 10.1039/D3OB01861J Cited by (2) \| Cite \| Source
A novel N -heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation (journal article) Zhang, Jiwei \| Liu, Chuanfeng \| Jia, Ruifang \| Zhang, Xujie \| Zhang, Jian \| Bertagnin, Chiara \| Bonomini, Anna \| Guizzo, Laura \| Jiang, Yuanmin \| Jia, Huinan \| ... \| Liu, Xinyong Journal of Enzyme Inhibition and Medicinal Chemistry, volume 38, issue 1 (2023). 10.1080/14756366.2023.2277135 Cite \| Source
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability (journal article) Gao, Shenghua \| Song, Letian \| Sylvester, Katharina \| Mercorelli, Beatrice \| Loregian, Arianna \| Toth, Karoly \| Weiße, Renato H. \| Useini, Abibe \| Sträter, Norbert \| Yang, Mianling \| ... \| Zhan, Peng Journal of Medicinal Chemistry, volume 66, issue 23, pages 16426-16440 (2023). 10.1021/acs.jmedchem.3c01876 Cited by (3) \| Cite \| Source
A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells (journal article) Bertagnin, Chiara \| Messa, Lorenzo \| Pavan, Matteo \| Celegato, Marta \| Sturlese, Mattia \| Mercorelli, Beatrice \| Moro, Stefano \| Loregian, Arianna Cancer Letters, volume 571 (2023). 10.1016/j.canlet.2023.216331 Cited by (5) \| Cite \| Source
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties (journal article) Jia, Ruifang \| Zhang, Jiwei \| Shi, Fangyuan \| Bonomini, Anna \| Lucca, Camilla \| Bertagnin, Chiara \| Zhang, Jian \| Liu, Chuanfeng \| Jia, Huinan \| Jiang, Yuanmin \| ... \| Liu, Xinyong European Journal of Medicinal Chemistry, volume 252 (2023). 10.1016/j.ejmech.2023.115275 Cited by (3) \| Cite \| Source
Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo (journal article) Celegato, Marta \| Sturlese, Mattia \| Vasconcelos Costa, Vivian \| Trevisan, Marta \| Lallo Dias, Angélica Samer \| Souza Passos, Ingredy Beatriz \| Queiroz-Junior, Celso Martins \| Messa, Lorenzo \| Favaro, Annagiulia \| Moro, Stefano \| ... \| Mercorelli, Beatrice mBio, volume 14, issue 1 (2023). 10.1128/mbio.03097-22 Cited by (5) \| Cite \| Source
Discovery of Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Anti-Influenza A Virus Agents for Overcoming N1-H274Y Oseltamivir-Resistant (journal article) Jia, Ruifang \| Zhang, Jiwei \| Zhang, Jian \| Bertagnin, Chiara \| Bonomini, Anna \| Guizzo, Laura \| Gao, Zhen \| Ji, Xiangkai \| Li, Zhuo \| Liu, Chuanfeng \| ... \| Liu, Xinyong Molecules, volume 27, issue 19, pages 6426- (2022). 10.3390/molecules27196426 Cited by (7) \| Cite \| Source
Iterative Optimization and Structure–Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity (journal article) Ju, Han \| Hou, Lingxin \| Zhao, Fabao \| Zhang, Ying \| Jia, Ruifang \| Guizzo, Laura \| Bonomini, Anna \| Zhang, Jiwei \| Gao, Zhen \| Liang, Ruipeng \| ... \| Zhan, Peng Journal of Medicinal Chemistry, volume 65, issue 17, pages 11550-11573 (2022). 10.1021/acs.jmedchem.1c01970 Cited by (7) \| Cite \| Source
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization (journal article) Mercorelli, Beatrice \| Desantis, Jenny \| Celegato, Marta \| Bazzacco, Alessandro \| Siragusa, Lydia \| Benedetti, Paolo \| Eleuteri, Michela \| Croci, Federico \| Cruciani, Gabriele \| Goracci, Laura \| Loregian, Arianna Antiviral Research, volume 204 (2022). 10.1016/j.antiviral.2022.105350 Cited by (13) \| Cite \| Source
Contemporary medicinal chemistry strategies for the discovery and optimization of influenza inhibitors targeting vRNP constituent proteins (journal article) Hou, Lingxin \| Zhang, Ying \| Ju, Han \| Cherukupalli, Srinivasulu \| Jia, Ruifang \| Zhang, Jian \| Huang, Bing \| Loregian, Arianna \| Liu, Xinyong \| Zhan, Peng Acta Pharmaceutica Sinica B, volume 12, issue 4, pages 1805-1824 (2022). 10.1016/j.apsb.2021.11.018 Cited by (14) \| Cite \| Source
HPV-induced cancers: preclinical therapeutic advancements (journal article) Messa, Lorenzo \| Loregian, Arianna Expert Opinion on Investigational Drugs, volume 31, issue 1, pages 79-93 (2022). 10.1080/13543784.2021.2010703 Cited by (3) \| Cite \| Source
Targeted Disruption of E6/p53 Binding Exerts Broad Activity and Synergism with Paclitaxel and Topotecan against HPV-Transformed Cancer Cells (journal article) Celegato, Marta \| Messa, Lorenzo \| Bertagnin, Chiara \| Mercorelli, Beatrice \| Loregian, Arianna Cancers, volume 14, issue 1, pages 193- (2021). 10.3390/cancers14010193 Cited by (7) \| Cite \| Source
Identification of C5-NH2 Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability (journal article) Ju, Han \| Murugan, N. Arul \| Hou, Lingxin \| Li, Ping \| Guizzo, Laura \| Zhang, Ying \| Bertagnin, Chiara \| Kong, Xiujie \| Kang, Dongwei \| Jia, Ruifang \| ... \| Zhan, Peng Journal of Medicinal Chemistry, volume 64, issue 24, pages 17992-18009 (2021). 10.1021/acs.jmedchem.1c01366 Cited by (15) \| Cite \| Source
Repurposing Approved Drugs to Block Highly Pathogenic Emerging Viruses (book chapter) In Antiviral Discovery for Highly Pathogenic Emerging Viruses Mercorelli, B. \| Loregian, A. The Royal Society of Chemistry (2021) 10.1039/9781788016858-00232 Cite \| Source
Indomethacin-based PROTACs as pan-coronavirus antiviral agents (journal article) Desantis, Jenny \| Mercorelli, Beatrice \| Celegato, Marta \| Croci, Federico \| Bazzacco, Alessandro \| Baroni, Massimo \| Siragusa, Lydia \| Cruciani, Gabriele \| Loregian, Arianna \| Goracci, Laura European Journal of Medicinal Chemistry, volume 226 (2021). 10.1016/j.ejmech.2021.113814 Cited by (49) \| Cite \| Source
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors (journal article) Pismataro, Maria Chiara \| Felicetti, Tommaso \| Bertagnin, Chiara \| Nizi, Maria Giulia \| Bonomini, Anna \| Barreca, Maria Letizia \| Cecchetti, Violetta \| Jochmans, Dirk \| De Jonghe, Steven \| Neyts, Johan \| ... \| Massari, Serena European Journal of Medicinal Chemistry, volume 221 (2021). 10.1016/j.ejmech.2021.113494 Cited by (19) \| Cite \| Source
The Dimeric Form of HPV16 E6 Is Crucial to Drive YAP/TAZ Upregulation through the Targeting of hScrib (journal article) Messa, Lorenzo \| Celegato, Marta \| Bertagnin, Chiara \| Mercorelli, Beatrice \| Alvisi, Gualtiero \| Banks, Lawrence \| Palù, Giorgio \| Loregian, Arianna Cancers, volume 13, issue 16, pages 4083- (2021). 10.3390/cancers13164083 Cited by (8) \| Cite \| Source
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs (journal article) Mercorelli, Beatrice \| Celegato, Marta \| Luganini, Anna \| Gribaudo, Giorgio \| Lepesheva, Galina I. \| Loregian, Arianna Antiviral Research, volume 189 (2021). 10.1016/j.antiviral.2021.105062 Cited by (5) \| Cite \| Source