Kristian Helin

ScholarGPS® ID: 95817496241070

Highly Ranked Scholar - Lifetime:

#14,090

Overall (All Fields)

#63

Cell growth

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Highly Ranked Scholar - Prior Five Years:

Recruitment

Affiliation

University of Copenhagen, Copenhagen, Denmark

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Metrics Summary

Publication Count

270

Predicted Citations

50,802

Predicted h-index

121

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Roles of H3K4 methylation in biology and disease (journal article) Wang, Hua \| Helin, Kristian Trends in Cell Biology (2024). 10.1016/j.tcb.2024.06.001 Cite \| Source
RIO-kinase 2 is essential for hematopoiesis (journal article) Messling, Jan-Erik \| Peña-Rømer, Isabel \| Moroni, Ann Sophie \| Bruestl, Sarah \| Helin, Kristian PLOS ONE, volume 19, issue 4, pages e0300623- (2024). 10.1371/journal.pone.0300623 Cite \| Source
TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers (journal article) Damhofer, Helene \| Tatar, Tülin \| Southgate, Benjamin \| Scarneo, Scott \| Agger, Karl \| Shlyueva, Daria \| Uhrbom, Lene \| Morrison, Gillian M. \| Hughes, Philip F. \| Haystead, Timothy \| ... \| Helin, Kristian Cell Death & Disease, volume 15, issue 4 (2024). 10.1038/s41419-024-06654-1 Cite \| Source
Keep quiet: the HUSH complex in transcriptional silencing and disease (journal article) Müller, Iris \| Helin, Kristian Nature Structural & Molecular Biology, volume 31, issue 1, pages 11-22 (2024). 10.1038/s41594-023-01173-7 Cited by (1) \| Cite \| Source
Discovery of NSD2‐Degraders from Novel and Selective DEL Hits (journal article) LegaardAndersson, Jan \| Christensen, Jesper \| Kleine‐Kohlbrecher, Daniela \| Vacher Comet, Itys \| Fullerton Støier, Jonatan \| Antoku, Yasuko \| Poljak, Visnja \| Moretti, Loris \| Dolberg, Johannes \| Jacso, Tomas \| ... \| Cloos, Paul A. C. ChemBioChem, volume 24, issue 24 (2023). 10.1002/cbic.202300515 Cited by (3) \| Cite \| Source
Cover Feature: Discovery of NSD2‐Degraders from Novel and Selective DEL Hits (ChemBioChem 24/2023) (journal article) LegaardAndersson, Jan \| Christensen, Jesper \| Kleine‐Kohlbrecher, Daniela \| Vacher Comet, Itys \| Fullerton Støier, Jonatan \| Antoku, Yasuko \| Poljak, Visnja \| Moretti, Loris \| Dolberg, Johannes \| Jacso, Tomas \| ... \| Cloos, Paul A. C. ChemBioChem, volume 24, issue 24 (2023). 10.1002/cbic.202300750 Cite \| Source
An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions (journal article) Radzisheuskaya, Aliaksandra \| Peña‐Rømer, Isabel \| Lorenzini, Eugenia \| Koche, Richard \| Zhan, Yingqian \| Shliaha, Pavel V \| Cooper, Alexandra J \| Fan, Zheng \| Shlyueva, Daria \| Johansen, Jens V \| ... \| Helin, Kristian The EMBO Journal, volume 42, issue 24 (2023). 10.15252/embj.2023114221 Cited by (2) \| Cite \| Source
Inhibition of Topors Ubiquitin Ligase Augments the Efficacy of DNA Hypomethylating Agents through DNMT1 Stabilization (journal article) Kaito, Satoshi \| Aoyama, Kazumasa \| Oshima, Motohiko \| Agger, Karl \| Helin, Kristian \| Nannya, Yasuhito \| Ogawa, Seishi \| Nishiyama, Atsuya \| Nakanishi, Makoto \| Iwama, Atsushi Blood, volume 142, issue Supplement 1, pages 414-414 (2023). 10.1182/blood-2023-179684 Cited by (1) \| Cite \| Source
Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation (journal article) Cheng, Kevin C. L. \| Frost, Jennifer M. \| Sánchez-Luque, Francisco J. \| García-Canãdas, Marta \| Taylor, Darren \| Yang, Wan R. \| Irayanar, Branavy \| Sampath, Swetha \| Patani, Hemalvi \| Agger, Karl \| ... \| Branco, Miguel R. Epigenetics & Chromatin, volume 16, issue 1 (2023). 10.1186/s13072-023-00514-6 Cited by (1) \| Cite \| Source
PR‐DUB safeguards Polycomb repression through H2AK119ub1 restriction (journal article) Li, Rui \| Huang, Dandan \| Zhao, Yingying \| Yuan, Ye \| Sun, Xiaoyu \| Dai, Zhongye \| Huo, Dawei \| Liu, Xiaozhi \| Helin, Kristian \| Li, Mulin Jun \| Wu, Xudong Cell Proliferation, volume 56, issue 10 (2023). 10.1111/cpr.13457 Cited by (3) \| Cite \| Source
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate (journal article) Hansen, Stine L. \| Larsen, Hjalte L. \| Pikkupeura, Laura M. \| Maciag, Grzegorz \| Guiu, Jordi \| Müller, Iris \| Clement, Ditte L. \| Mueller, Christina \| Johansen, Jens Vilstrup \| Helin, Kristian \| ... \| Jensen, Kim B. Science Advances, volume 9, issue 28 (2023). 10.1126/sciadv.adg4055 Cited by (11) \| Cite \| Source
Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1 (journal article) Sun, Zhen \| Lin, Yuan \| Islam, Mohammed T. \| Koche, Richard \| Hedehus, Lin \| Liu, Dingyu \| Huang, Chang \| Vierbuchen, Thomas \| Sawyers, Charles L. \| Helin, Kristian Molecular Cell, volume 83, issue 14, pages 2398-2416.e12 (2023). 10.1016/j.molcel.2023.06.007 Cited by (6) \| Cite \| Source
The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing (journal article) Bischoff, Nadja \| Wimberger, Sandra \| Kühn, Ralf \| Laugesen, Anne \| Turan, Volkan \| Larsen, Brian Daniel \| Sørensen, Claus Storgaard \| Helin, Kristian \| Bennett, Eric Paul \| Maresca, Marcello \| Brakebusch, Cord Gene and Genome Editing, volume 5 (2023). 10.1016/j.ggedit.2022.100023 Cite \| Source
H3K4me3 regulates RNA polymerase II promoter-proximal pause-release (journal article) Wang, Hua \| Fan, Zheng \| Shliaha, Pavel V. \| Miele, Matthew \| Hendrickson, Ronald C. \| Jiang, Xuejun \| Helin, Kristian Nature, volume 615, issue 7951, pages 339-348 (2023). 10.1038/s41586-023-05780-8 Cited by (89) \| Cite \| Source
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes (journal article) Trempenau, Mette Louise \| Schuster, Mikkel Bruhn \| Pundhir, Sachin \| Pereira, Mafalda Araujo \| Kalvisa, Adrija \| Tapia, Marta \| Su, Jinyu \| Ge, Ying \| de Boer, Bauke \| Balhuizen, Alexander \| ... \| Porse, Bo T. Leukemia, volume 37, issue 3, pages 593-605 (2023). 10.1038/s41375-023-01810-6 Cited by (7) \| Cite \| Source
3151 – THE ALTERNATIVE NUCLEOSOME REMODELING FACTOR COMPLEX SUSTAINS ACUTE MYELOID LEUKEMIA BY REGULATING THE ACCESSIBILITY OF INSULATOR REGIONS (journal article) Roemer, Isabel Pena \| Radzisheuskaya, Aliaksandra \| Lorenzini, Eugenia \| Koche, Richard \| Zhan, Yingqian \| Shliaha, Pavel V \| Cooper, Alexandra \| Shlyueva, Daria \| Johansen, Jens \| Hendrickson, Ronald \| Helin, Kristian Experimental Hematology, volume 124 (2023). 10.1016/j.exphem.2023.06.258 Cite \| Source
BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation (journal article) Li, Bing \| An, Wenbin \| Wang, Hua \| Baslan, Timour \| Mowla, Shoron \| Krishnan, Aishwarya \| Xiao, Wenbin \| Koche, Richard P. \| Liu, Ying \| Cai, Sheng F. \| ... \| Rampal, Raajit K. Blood, volume 139, issue 25, pages 3630-3646 (2022). 10.1182/blood.2021014465 Cited by (10) \| Cite \| Source
Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals (journal article) Sankar, Aditya \| Mohammad, Faizaan \| Sundaramurthy, Arun Kumar \| Wang, Hua \| Lerdrup, Mads \| Tatar, Tulin \| Helin, Kristian Nature Genetics, volume 54, issue 6, pages 754-760 (2022). 10.1038/s41588-022-01091-2 Cited by (53) \| Cite \| Source
Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression (journal article) Garland, William \| Müller, Iris \| Wu, Mengjun \| Schmid, Manfred \| Imamura, Katsutoshi \| Rib, Leonor \| Sandelin, Albin \| Helin, Kristian \| Jensen, Torben Heick Molecular Cell, volume 82, issue 9, pages 1691-1707.e8 (2022). 10.1016/j.molcel.2022.03.004 Cited by (37) \| Cite \| Source
H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway (journal article) Hansen, Anne Meldgaard \| Ge, Ying \| Schuster, Mikkel Bruhn \| Pundhir, Sachin \| Jakobsen, Janus Schou \| Kalvisa, Adrija \| Tapia, Marta Cecylia \| Gordon, Sandra \| Ambri, Francesca \| Bagger, Frederik Otzen \| ... \| Porse, Bo Torben Science Advances, volume 8, issue 11 (2022). 10.1126/sciadv.abf8627 Cited by (16) \| Cite \| Source