Vladimír Wsól

ScholarGPS® ID: 95505124796181

Affiliation

Charles University, Prague, Czechia

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacy

Top Specialties

Metrics Summary

Publication Count

115

Predicted Citations

2,572

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters (journal article) Morell, Anselm \| Budagaga, Youssif \| Vagiannis, Dimitrios \| Zhang, Yu \| Laštovičková, Lenka \| Novotná, Eva \| Haddad, Andrew \| Haddad, Melodie \| Portillo, Ramon \| Hofman, Jakub \| Wsól, Vladimír Archives of Toxicology, volume 96, issue 12, pages 3265-3277 (2022). 10.1007/s00204-022-03359-2 Cited by (4) \| Cite \| Source
Bruton’s Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux (journal article) Čermáková, Lucie \| Hofman, Jakub \| Laštovičková, Lenka \| Havlíčková, Lucie \| Špringrová, Ivona \| Novotná, Eva \| Wsól, Vladimír Pharmaceutics, volume 14, issue 10, pages 1994- (2022). 10.3390/pharmaceutics14101994 Cited by (5) \| Cite \| Source
Inhibition of AKR1B10-mediated metabolism of daunorubicin as a novel off-target effect for the Bcr-Abl tyrosine kinase inhibitor dasatinib (journal article) Büküm, Neslihan \| Novotná, Eva \| Morell, Anselm \| Želazková, Jana \| Laštovičková, Lenka \| Čermáková, Lucie \| Portillo, Ramon \| Solich, Petr \| Wsól, Vladimír Biochemical Pharmacology, volume 192 (2021). 10.1016/j.bcp.2021.114710 Cited by (3) \| Cite \| Source
Late Breaking Abstract - Aldo-keto reductases expression correlate corticoids efficacy in vitro and on chronic rhinosinusitis with nasal polyps (conference) Morell, Anselm \| Milara, Javier \| Laštovičková, Lenka \| Roger, Inés \| García-Lliberós, Ainhoa \| Zapater-Latorre, Enrique \| Armengot, Miguel \| Cortijo, Julio \| Wsól, Vladimir ERS International Congress 2021 abstracts (2021) 10.1183/13993003.congress-2021.PA891 Cite \| Source
Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism (journal article) Morell, Anselm \| Novotná, Eva \| Milan, Jaroslav \| Danielisová, Petra \| Büküm, Neslihan \| Wsól, Vladimír Archives of Toxicology, volume 95, issue 1, pages 67-78 (2021). 10.1007/s00204-020-02884-2 Cited by (6) \| Cite \| Source
Bruton’s Tyrosine Kinase Inhibitors Ibrutinib and Acalabrutinib Counteract Anthracycline Resistance in Cancer Cells Expressing AKR1C3 (journal article) Morell, Anselm \| Čermáková, Lucie \| Novotná, Eva \| Laštovičková, Lenka \| Haddad, Melodie \| Haddad, Andrew \| Portillo, Ramon \| Wsól, Vladimír Cancers, volume 12, issue 12, pages 3731- (2020). 10.3390/cancers12123731 Cited by (11) \| Cite \| Source
Olaparib Synergizes the Anticancer Activity of Daunorubicin via Interaction with AKR1C3 (journal article) Tavares, Tássia S. \| Hofman, Jakub \| Lekešová, Alžběta \| Želazková, Jana \| Wsól, Vladimír Cancers, volume 12, issue 11, pages 3127- (2020). 10.3390/cancers12113127 Cited by (7) \| Cite \| Source
Interactions of antileukemic drugs with daunorubicin reductases: could reductases affect the clinical efficacy of daunorubicin chemoregimens? (journal article) Novotná, Eva \| Morell, Anselm \| Büküm, Neslihan \| Hofman, Jakub \| Danielisová, Petra \| Wsól, Vladimír Archives of Toxicology, volume 94, issue 9, pages 3059-3068 (2020). 10.1007/s00204-020-02818-y Cited by (5) \| Cite \| Source
Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors (journal article) Sorf, Ales \| Sucha, Simona \| Morell, Anselm \| Novotna, Eva \| Staud, Frantisek \| Zavrelova, Alzbeta \| Visek, Benjamin \| Wsol, Vladimir \| Ceckova, Martina Cancers, volume 12, issue 6, pages 1596- (2020). 10.3390/cancers12061596 Cited by (16) \| Cite \| Source
Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters (journal article) Sorf, Ales \| Novotna, Eva \| Hofman, Jakub \| Morell, Anselm \| Staud, Frantisek \| Wsol, Vladimir \| Ceckova, Martina Biochemical Pharmacology, volume 163 (2019). 10.1016/j.bcp.2019.02.035 Cited by (9) \| Cite \| Source
Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3 (journal article) Bukum, Neslihan \| Novotna, Eva \| Morell, Anselm \| Hofman, Jakub \| Wsol, Vladimir Chemico-Biological Interactions, volume 302 (2019). 10.1016/j.cbi.2019.01.026 Cited by (11) \| Cite \| Source
Initial characterization of human DHRS1 (SDR19C1), a member of the short-chain dehydrogenase/reductase superfamily (journal article) Zemanová, Lucie \| Navrátilová, Hana \| Andrýs, Rudolf \| Šperková, Kristýna \| Andrejs, Jiří \| Kozáková, Klára \| Meier, Marc \| Möller, Gabriele \| Novotná, Eva \| Šafr, Miroslav \| ... \| Wsól, Vladimír The Journal of Steroid Biochemistry and Molecular Biology, volume 185 (2019). 10.1016/j.jsbmb.2018.07.013 Cited by (6) \| Cite \| Source
Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment (journal article) Novotná, Eva \| Büküm, Neslihan \| Hofman, Jakub \| Flaxová, Michaela \| Kouklíková, Etela \| Louvarová, Dagmar \| Wsól, Vladimír Biochemical Pharmacology, volume 156 (2018). 10.1016/j.bcp.2018.08.001 Cited by (22) \| Cite \| Source
Aldo-keto reductase 1C3 (AKR1C3): a missing piece of the puzzle in the dinaciclib interaction profile (journal article) Novotná, Eva \| Büküm, Neslihan \| Hofman, Jakub \| Flaxová, Michaela \| Kouklíková, Etela \| Louvarová, Dagmar \| Wsól, Vladimír Archives of Toxicology, volume 92, issue 9, pages 2845-2857 (2018). 10.1007/s00204-018-2258-0 Cited by (24) \| Cite \| Source
Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes (journal article) Malátková, Petra \| Skarka, Adam \| Musilová, Kateřina \| Wsól, Vladimír Chemico-Biological Interactions, volume 276 (2017). 10.1016/j.cbi.2017.03.006 Cited by (2) \| Cite \| Source
Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity (journal article) Novotná, Eva \| Waisser, Karel \| Kuneš, Jiří \| Palát, Karel \| Skálová, Lenka \| Szotáková, Barbora \| Buchta, Vladimír \| Stolaříková, Jiřina \| Ulmann, Vít \| Pávová, Marcela \| ... \| Wsól, Vladimír Archiv der Pharmazie, volume 350, issue 8 (2017). 10.1002/ardp.201700020 Cited by (6) \| Cite \| Source
Acetylcholinesterase Inhibitors and Drugs Acting on Muscarinic Receptors- Potential Crosstalk of Cholinergic Mechanisms During Pharmacological Treatment (journal article) Soukup, Ondrej \| Winder, Michael \| Killi, Uday Kumar \| Wsol, Vladimir \| Jun, Daniel \| Kuca, Kamil \| Tobin, Gunnar Current Neuropharmacology, volume 15, issue 4, pages 637-653 (2017). 10.2174/1570159X14666160607212615 Cited by (20) \| Cite \| Source \| Open Access
AKR1C3 Inhibitory Potency of Naturally-occurring Amaryllidaceae Alkaloids of Different Structural Types (journal article) Hulcová, Daniela \| Breiterová, Kateřina \| Zemanová, Lucie \| Siatka, Tomáš \| Šafratová, Marcela \| Vaněčková, Nina \| Hošťálková, Anna \| Wsól, Vladimír \| Cahlíková, Lucie Natural Product Communications, volume 12, issue 2, pages 1934578X1701200- (2017). 10.1177/1934578X1701200226 Cited by (8) \| Cite \| Source
In vitro metabolism of fenofibric acid by carbonyl reducing enzymes (journal article) Malátková, Petra \| Kanavi, Matthildi \| Nobilis, Milan \| Wsól, Vladimír Chemico-Biological Interactions, volume 258 (2016). 10.1016/j.cbi.2016.09.001 Cited by (7) \| Cite \| Source
Carbonyl reduction of warfarin: Identification and characterization of human warfarin reductases (journal article) Malátková, Petra \| Sokolová, Simona \| Chocholoušová Havlíková, Lucie \| Wsól, Vladimír Biochemical Pharmacology, volume 109 (2016). 10.1016/j.bcp.2016.03.025 Cited by (18) \| Cite \| Source