Lee L. Rubin

ScholarGPS® ID: 95217116945423

Affiliation

Harvard University, Cambridge, United States

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Metrics Summary

Publication Count

132

Predicted Citations

16,411

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy (journal article) Leow, Damien Meng-Kiat \| Ng, Yang Kai \| Wang, Loo Chien \| Koh, Hiromi W.L. \| Zhao, Tianyun \| Khong, Zi Jian \| Tabaglio, Tommaso \| Narayanan, Gunaseelan \| Giadone, Richard M. \| Sobota, Radoslaw M. \| ... \| Yeo, Crystal J.J. Journal of Clinical Investigation, volume 134, issue 12 (2024). 10.1172/JCI173702 Cite \| Source
Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets (journal article) Watts, Michelle E. \| Giadone, Richard M. \| Ordureau, Alban \| Holton, Kristina M. \| Harper, J. Wade \| Rubin, Lee L. Frontiers in Cellular Neuroscience, volume 17 (2024). 10.3389/fncel.2023.1327361 Cite \| Source
GDF11 and aging biology - controversies resolved and pending (journal article) Driss, Laura Ben \| Lian, John \| Walker, Ryan G. \| Howard, James A. \| Thompson, Thomas B. \| Rubin, Lee L. \| Wagers, Amy J. \| Lee, Richard T. The Journal of Cardiovascular Aging, volume 3, issue 4 (2023). 10.20517/jca.2023.23 Cite \| Source
A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides (journal article) Paul, Kimberly C. \| Krolewski, Richard C. \| Lucumi Moreno, Edinson \| Blank, Jack \| Holton, Kristina M. \| Ahfeldt, Tim \| Furlong, Melissa \| Yu, Yu \| Cockburn, Myles \| Thompson, Laura K. \| ... \| Ritz, Beate Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-38215-z Cited by (23) \| Cite \| Source
High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly (journal article) Berryer, Martin H \| Rizki, Gizem \| Nathanson, Anna \| Klein, Jenny A \| Trendafilova, Darina \| Susco, Sara G \| Lam, Daisy \| Messana, Angelica \| Holton, Kristina M \| Karhohs, Kyle W \| ... \| Barrett, Lindy E eLife, volume 12 (2023). 10.7554/eLife.80168 Cited by (4) \| Cite \| Source
Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy–induced toxicities (journal article) Spetz, Johan K. E. \| Florido, Mary H. C. \| Fraser, Cameron S. \| Qin, Xingping \| Choiniere, Jonathan \| Yu, Stacey J. \| Singh, Rumani \| Friesen, Max \| Rubin, Lee L. \| Salem, Joe-Elie \| ... \| Sarosiek, Kristopher A. Science Advances, volume 8, issue 45 (2022). 10.1126/sciadv.abn6579 Cited by (7) \| Cite \| Source
Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer (journal article) Cronin, Shane J. F. \| Rao, Shuan \| Tejada, Miguel A. \| Turnes, Bruna Lenfers \| Licht-Mayer, Simon \| Omura, Takao \| Brenneis, Christian \| Jacobs, Emily \| Barrett, Lee \| Latremoliere, Alban \| ... \| Woolf, Clifford J. Science Translational Medicine, volume 14, issue 660 (2022). 10.1126/scitranslmed.abj1531 Cited by (14) \| Cite \| Source
A microengineered Brain-Chip to model neuroinflammation in humans (journal article) Pediaditakis, Iosif \| Kodella, Konstantia R. \| Manatakis, Dimitris V. \| Le, Christopher Y. \| Barthakur, Sonalee \| Sorets, Alexander \| Gravanis, Achille \| Ewart, Lorna \| Rubin, Lee L. \| Manolakos, Elias S. \| ... \| Karalis, Katia iScience, volume 25, issue 8, pages 104813- (2022). 10.1016/j.isci.2022.104813 Cited by (26) \| Cite \| Source
Accelerating diagnosis of Parkinson’s disease through risk prediction (journal article) Yuan, William \| Beaulieu-Jones, Brett \| Krolewski, Richard \| Palmer, Nathan \| Veyrat-Follet, Christine \| Frau, Francesca \| Cohen, Caroline \| Bozzi, Sylvie \| Cogswell, Meaghan \| Kumar, Dinesh \| ... \| Lipnick, Scott L. BMC Neurology, volume 21, issue 1 (2021). 10.1186/s12883-021-02226-4 Cited by (15) \| Cite \| Source
GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis (journal article) Mayweather, Brittany A. \| Buchanan, Sean M. \| Rubin, Lee L. Molecular Brain, volume 14, issue 1 (2021). 10.1186/s13041-021-00845-z Cited by (14) \| Cite \| Source
Assessing kinetics and recruitment of DNA repair factors using high content screens (journal article) Martinez-Pastor, Barbara \| Silveira, Giorgia G. \| Clarke, Thomas L. \| Chung, Dudley \| Gu, Yuchao \| Cosentino, Claudia \| Davidow, Lance S. \| Mata, Gadea \| Hassanieh, Sylvana \| Salsman, Jayme \| ... \| Mostoslavsky, Raul Cell Reports, volume 37, issue 13, pages 110176- (2021). 10.1016/j.celrep.2021.110176 Cited by (7) \| Cite \| Source
Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption (journal article) Pediaditakis, Iosif \| Kodella, Konstantia R. \| Manatakis, Dimitris V. \| Le, Christopher Y. \| Hinojosa, Chris D. \| Tien-Street, William \| Manolakos, Elias S. \| Vekrellis, Kostas \| Hamilton, Geraldine A. \| Ewart, Lorna \| ... \| Karalis, Katia Nature Communications, volume 12, issue 1 (2021). 10.1038/s41467-021-26066-5 Cited by (113) \| Cite \| Source
Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells (journal article) Sadegh, Cameron \| Ebina, Wataru \| Arvanites, Anthony C. \| Davidow, Lance S. \| Rubin, Lee L. \| Macklis, Jeffrey D. PLOS ONE, volume 16, issue 9, pages e0254113- (2021). 10.1371/journal.pone.0254113 Cited by (2) \| Cite \| Source
Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging (journal article) Tomov, Martin L. \| O’Neil, Alison \| Abbasi, Hamdah S. \| Cimini, Beth A. \| Carpenter, Anne E. \| Rubin, Lee L. \| Bathe, Mark Communications Biology, volume 4, issue 1 (2021). 10.1038/s42003-021-02276-x Cited by (6) \| Cite \| Source
FOS licenses early events in stem cell activation driving skeletal muscle regeneration (journal article) Almada, Albert E. \| Horwitz, Naftali \| Price, Feodor D. \| Gonzalez, Alfredo E. \| Ko, Michelle \| Bolukbasi, Ozge Vargel \| Messemer, Kathleen A. \| Chen, Sonia \| Sinha, Manisha \| Rubin, Lee L. \| Wagers, Amy J. Cell Reports, volume 34, issue 4, pages 108656- (2021). 10.1016/j.celrep.2020.108656 Cited by (43) \| Cite \| Source
Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells (journal article) Buchanan, Sean M. \| Price, Feodor D. \| Castiglioni, Alessandra \| Gee, Amanda Wagner \| Schneider, Joel \| Matyas, Mark N. \| Hayhurst, Monica \| Tabebordbar, Mohammadsharif \| Wagers, Amy J. \| Rubin, Lee L. Skeletal Muscle, volume 10, issue 1 (2020). 10.1186/s13395-020-00248-z Cited by (8) \| Cite \| Source
Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy (journal article) Walsh, Melissa B. \| Janzen, Eva \| Wingrove, Emily \| Hosseinibarkooie, Seyyedmohsen \| Muela, Natalia Rodriguez \| Davidow, Lance \| Dimitriadi, Maria \| Norabuena, Erika M. \| Rubin, Lee L. \| Wirth, Brunhilde \| Hart, Anne C. BMC Biology, volume 18, issue 1 (2020). 10.1186/s12915-020-00845-w Cited by (11) \| Cite \| Source
Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis (journal article) Toyohara, Takafumi \| Roudnicky, Filip \| Florido, Mary H.C. \| Nakano, Toshiaki \| Yu, Haojie \| Katsuki, Shunsuke \| Lee, Minjin \| Meissner, Torsten \| Friesen, Max \| Davidow, Lance S. \| ... \| Cowan, Chad A. Cell Stem Cell, volume 27, issue 1, pages 147-157.e7 (2020). 10.1016/j.stem.2020.04.018 Cited by (15) \| Cite \| Source
Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance (patent) Rossi, Derrick J. \| Ebina, Wataru \| Stewart, Morag \| Gutierrez-Martinez, Paula \| Rubin, Lee L. \| Davidow, Lance Patent Number: 10669528 (2020) Cite \| Source
Method of increasing satellite cell proliferation with an HDAC inhibitor (patent) Rubin, Lee L. \| Gee, Amanda \| Wagers, Amy J. Patent Number: 10660902 (2020) Cite \| Source

Title	Investigators	Year	Cost	Agency
Identifying and Correcting Dementia-Associated Changes in the Blood-Brain Barrier	Rubin, LEE L	2020	$2,366,000	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Mammalian motor neuron SMN screens	Rubin, LEE L	2014	$288,277	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Mammalian motor neuron SMN screens	Rubin, LEE L	2013	$287,359	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Mammalian motor neuron SMN screens	Rubin, LEE L	2012	$303,805	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Mammalian motor neuron SMN screens	Rubin, LEE L	2011	$310,753	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Mammalian motor neuron SMN screens	Rubin, LEE L	2010	$321,626	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
MOLECULAR COMPONENTS OF ACETYLCHOLINE RECEPTOR CLUSTERS	Rubin, LEE L	1990	$217,204	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
MOLECULAR COMPONENTS OF ACETYLCHOLINE RECEPTOR CLUSTERS	Rubin, LEE L	1989	$217,204	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
MOLECULAR COMPONENTS OF ACETYLCHOLINE RECEPTOR CLUSTERS	Rubin, LEE L	1988	$203,771	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
MOLECULAR COMPONENTS OF ACETYLCHOLINE RECEPTOR CLUSTERS	Rubin, LEE L	1987	$91,519	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
MOLECULAR COMPONENTS OF ACETYLCHOLINE RECEPTOR CLUSTERS	Rubin, LEE L	1986	$85,051	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
MOLECULAR COMPONENTS OF ACETYLCHOLINE RECEPTOR CLUSTERS	Rubin, LEE L	1985	$77,802	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE