Ian E. Krop

ScholarGPS® ID: 93342651152051

Affiliation
Dana-Farber Cancer Institute, Boston, United States
Affiliation History

Field
Medicine
Discipline
Oncology
Top Specialties
Cancer | Breast Cancer | Trastuzumab | Metastatic Breast Cancer | Neoplasm | Chemotherapy | Epidermal Growth Factor | Epidermal Growth Factor Receptor | Growth Factor Receptor | Brain Metastasis | Paclitaxel | Antibody | Antibody-drug Conjugate | Biomarker | Capecitabine
Metrics Summary
Publication Count
296
Predicted Citations
30,532
Predicted h-index
87
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Outcomes with trastuzumab deruxtecan (T-DXd) by HER2 status and line of treatment in a large real-world database of patients with metastatic breast cancer. (journal article)
Tarantino, Paolo | Lee, Do | Foldi, Julia | Soulos, Pamela R. | Gross, Cary Philip | Grinda, Thomas | Winer, Eric P. | Lin, Nancy U. | Krop, Ian E. | Tolaney, Sara M. | ... | Sammons, Sarah L
Journal of Clinical Oncology, volume 42, issue 16_suppl, pages 1077-1077 (2024).
10.1200/JCO.2024.42.16_suppl.1077
Cite | Source
TBCRC 048 (olaparib expanded) expansion cohorts: Phase 2 study of olaparib monotherapy in patients (pts) with metastatic breast cancer (MBC) with germline (g) mutations in PALB2 or somatic (s) mutations in BRCA1 or BRCA2. (journal article)
Tung, Nadine M. | Robson, Mark E. | Nanda, Rita | Li, Tianyu | Vinayak, Shaveta | Shah, Payal Deepak | Khoury, Katia | Kimmick, Gretchen Genevieve | Santa-Maria, Cesar Augusto | Brufsky, Adam | ... | Garber, Judy Ellen
Journal of Clinical Oncology, volume 42, issue 16_suppl, pages 1021-1021 (2024).
10.1200/JCO.2024.42.16_suppl.1021
Cited by (2) | Cite | Source
Phase Ib dose-escalation trial of taselisib (GDC-0032) in combination with HER2-directed therapies in patients with advanced HER2+ breast cancer (journal article)
Grinshpun, A. | Ren, S. | Graham, N. | DeMeo, M.K. | Wrabel, E. | Carter, J. | Tayob, N. | Pereslete, A. | Hamilton, E. | Juric, D. | ... | Metzger, O.
ESMO Open, volume 9, issue 6, pages 103465- (2024).
10.1016/j.esmoop.2024.103465
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ETHAN: A phase II study comparing different endocrine therapies for male breast cancer. (journal article)
Leone, Jose Pablo | Ruddy, Kathryn Jean | Rashid, Naim | Giordano, Sharon H. | Gupta, Gaorav P. | Hilsenbeck, Susan G. | Gucalp, Ayca | Walsh, Elaine M. | Sukumar, Jasmine S | Makhlin, Igor | ... | Thompson, Alastair Mark
Journal of Clinical Oncology, volume 42, issue 16_suppl, pages TPS632-TPS632 (2024).
10.1200/JCO.2024.42.16_suppl.TPS632
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Trastuzumab deruxtecan versus treatment of physician's choice in patients with HER2-positive metastatic breast cancer (DESTINY-Breast02): patient-reported outcomes from a randomised, open-label, multicentre, phase 3 trial (journal article)
Fehm, Tanja | Cottone, Francesco | Dunton, Kyle | André, Fabrice | Krop, Ian | Park, Yeon Hee | De Laurentiis, Michelino | Miyoshi, Yasuo | Armstrong, Anne | Borrego, Manuel Ruiz | ... | Kim, Sung-Bae
The Lancet Oncology, volume 25, issue 5, pages 614-625 (2024).
10.1016/S1470-2045(24)00128-1
Cited by (2) | Cite | Source
267MO Pooled analysis of trastuzumab deruxtecan (T-DXd) retreatment (RTx) after recovery from grade (Gr) 1 interstitial lung disease/pneumonitis (ILD) (journal article)
Rugo, H.S. | Tokunaga, E. | Iwata, H. | Petry, V. | Smit, E.F. | Goto, Y. | Kim, D-W. | Shitara, K. | Gruden, J.F. | Modi, S. | ... | Powell, C.A.
ESMO Open, volume 9 (2024).
10.1016/j.esmoop.2024.103326
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Trastuzumab deruxtecan in previously treated patients with HER2-positive metastatic breast cancer: updated survival results from a phase II trial (DESTINY-Breast01) (journal article)
Saura, C. | Modi, S. | Krop, I. | Park, Y.H. | Kim, S.-B. | Tamura, K. | Iwata, H. | Tsurutani, J. | Sohn, J. | Mathias, E. | ... | Yamashita, T.
Annals of Oncology, volume 35, issue 3, pages 302-307 (2024).
10.1016/j.annonc.2023.12.001
Cited by (9) | Cite | Source
Prediction of Benefit From Adjuvant Pertuzumab by 80-Gene Signature in the APHINITY (BIG 4-11) Trial (journal article)
Krop, Ian E. | Mittempergher, Lorenza | Paulson, Joseph N. | Andre, Fabrice | Bonnefoi, Herve | Loi, Sherene | Loibl, Sibylle | Gelber, Richard D. | Caballero, Carmela | Bhaskaran, Rajith | ... | Piccart, Martine J.
JCO Precision Oncology (2024).
10.1200/PO.22.00667
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Axillary Nodal Response to Neoadjuvant T-DM1 Combined with Pertuzumab in a Prospective Phase II Multi-Institution Clinical Trial (journal article)
Weiss, Anna | Jin, Qingchun | Waks, Adrienne G | Yardley, Denise | Spring, Laura M | Wrabel, Eileen | Tayob, Nabihah | Viale, Giuseppe | Krop, Ian E | King, Tari A | Metzger-Filho, Otto
Journal of the American College of Surgeons, volume 238, issue 3, pages 303-311 (2024).
10.1097/XCS.0000000000000916
Cited by (2) | Cite | Source
PS2-4 Phase 1/2 study of HER3-DXd in HER3-expressing metastatic breast cancer: Subgroup analysis by HER2 expression (journal article)
Iwata, Hiroji | Krop, Ian E. | Masuda, Norikazu | Mukohara, Toru | Takahashi, Shunji | Nakayama, Takahiro | Inoue, Kenichi | Toyama, Tatsuya | Yamamoto, Yutaka | Alvarez, Ricardo H. | ... | Sellami, Dalila
Annals of Oncology, volume 34 (2023).
10.1016/j.annonc.2023.09.107
Cited by (2) | Cite | Source
ER +, HER2 − advanced breast cancer treated with taselisib and fulvestrant: genomic landscape and associated clinical outcomes (journal article)
Chen, Jessica W. | Jacot, William | Cortés, Javier | Krop, Ian E. | Dent, Susan | Harbeck, Nadia | De Laurentiis, Michelino | Diéras, Véronique | Im, Young‐Hyuck | Stout, Thomas J. | ... | Wilson, Timothy R.
Molecular Oncology, volume 17, issue 10, pages 2000-2016 (2023).
10.1002/1878-0261.13416
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Genomics of ERBB2 -Positive Breast Cancer in Young Women Before and After Exposure to Chemotherapy Plus Trastuzumab (journal article)
Lipsyc-Sharf, Marla | Jain, Esha | Collins, Laura C. | Rosenberg, Shoshana M. | Ruddy, Kathryn J. | Tamimi, Rulla M. | Schapira, Lidia | Come, Steven E. | Peppercorn, Jeffrey M. | Borges, Virginia F. | ... | Waks, Adrienne G.
JCO Precision Oncology (2023).
10.1200/PO.23.00076
Cited by (1) | Cite | Source
Trends in breast cancer death by stage at diagnoses in 2000-2018. (journal article)
Kahn, Adriana Matutino | Marczyk, Michal | Silber, Andrea | Rozenblit, Mariya | Sanft, Tara B. | DiGiovanna, Michael | Schellhorn, Sarah | Krop, Ian E. | Lustberg, Maryam B. | Winer, Eric P. | Pusztai, Lajos
Journal of Clinical Oncology, volume 41, issue 16_suppl, pages e18855-e18855 (2023).
10.1200/JCO.2023.41.16_suppl.e18855
Cited by (1) | Cite | Source
An age-specific pooled analysis of trastuzumab deruxtecan (T-DXd) in patients (pts) with HER2-positive (HER2+) metastatic breast cancer (mBC) from DESTINY-Breast01, -02, and -03. (journal article)
Krop, Ian E. | Wildiers, Hans | Hurvitz, Sara A. | Cortes, Javier | Im, Seock-Ah | Iwata, Hiroji | Andre, Fabrice | Saura, Cristina | Modi, Shanu | Kim, Sung-Bae | ... | Park, Yeon Hee
Journal of Clinical Oncology, volume 41, issue 16_suppl, pages 1006-1006 (2023).
10.1200/JCO.2023.41.16_suppl.1006
Cited by (3) | Cite | Source
186O Patient-reported outcomes (PROs) from DESTINY-Breast02, a randomized phase III study of trastuzumab deruxtecan (T-DXd) vs treatment of physician’s choice (TPC) in patients (pts) with HER2–positive (HER2+) metastatic breast cancer (mBC) (journal article)
Fehm, T.N. | Cottone, F. | Dunton, K. | André, F. | Krop, I. | Park, Y.H. | De Laurentiis, M. | Miyoshi, Y. | Armstrong, A. | Borrego, M. Ruiz | ... | Kim, S-B.
ESMO Open, volume 8, issue 1, pages 101375- (2023).
10.1016/j.esmoop.2023.101375
Cited by (1) | Cite | Source
6P Combined analysis of the HER2DX genomic tool in adjuvant APT and ATEMPT trials (journal article)
Tarantino, P. | Villacampa, G. | Graham, N. | Waks, A.G. | Gonzalez, P. Villagrasa | Brasó-Maristany, F. | Torres, E. Sanfeliu | Galván, P. | Brunet, L. Pare | Demeo, M.K. | ... | Tolaney, S.M.
ESMO Open, volume 8, issue 1, pages 101230- (2023).
10.1016/j.esmoop.2023.101230
Cited by (1) | Cite | Source
Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2–, PIK3CA-mutated breast cancers (journal article)
Hutchinson, Katherine E. | Chen, Jessica W. | Savage, Heidi M. | Stout, Thomas J. | Schimmoller, Frauke | Cortés, Javier | Dent, Susan | Harbeck, Nadia | Jacot, William | Krop, Ian | ... | Wilson, Timothy R.
Genome Medicine, volume 15, issue 1 (2023).
10.1186/s13073-023-01181-8
Cited by (8) | Cite | Source
Prognostic and Predictive Value of Immune-Related Gene Expression Signatures vs Tumor-Infiltrating Lymphocytes in Early-Stage ERBB2/HER2-Positive Breast Cancer (journal article)
Fernandez-Martinez, Aranzazu | Pascual, Tomás | Singh, Baljit | Nuciforo, Paolo | Rashid, Naim U. | Ballman, Karla V. | Campbell, Jordan D. | Hoadley, Katherine A. | Spears, Patricia A. | Pare, Laia | ... | Carey, Lisa A.
JAMA Oncology, volume 9, issue 4, pages 490- (2023).
10.1001/jamaoncol.2022.6288
Cited by (17) | Cite | Source
Nodal Positivity in Early-Stage Triple-Negative Breast Cancer: Implications for Preoperative Immunotherapy (journal article)
Mittendorf, Elizabeth A. | Kantor, Olga | Weiss, Anna | Richardson, Edward | Garrido-Castro, Ana | Portnow, Leah H. | Krop, Ian E. | Lin, Nancy U. | Winer, Eric P. | Tolaney, Sara M. | King, Tari A.
Annals of Surgical Oncology, volume 30, issue 1, pages 100-106 (2023).
10.1245/s10434-022-12357-8
Cited by (8) | Cite | Source
Trastuzumab Deruxtecan in HER2-Positive Metastatic Breast Cancer Patients with Brain Metastases: A DESTINY-Breast01 Subgroup Analysis (journal article)
Jerusalem, Guy | Park, Yeon Hee | Yamashita, Toshinari | Hurvitz, Sara A. | Modi, Shanu | Andre, Fabrice | Krop, Ian E. | Gonzàlez Farré, Xavier | You, Benoit | Saura, Cristina | ... | Perrin, Christophe
Cancer Discovery, volume 12, issue 12, pages 2754-2762 (2022).
10.1158/2159-8290.CD-22-0837
Cited by (38) | Cite | Source