Dorothea Reilly

ScholarGPS® ID: 92371555198915

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Antibody | Biotechnology | Escherichia Coli | Melanoma | Bacteria

Metrics Summary

Publication Count

Predicted Citations

3,258

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Bioprocess Development and Characterization of a 13C-Labeled Hybrid Bispecific Antibody Produced in Escherichia coli (journal article) Wecksler, Aaron T. \| Lundin, Victor \| Williams, Ambrose J. \| Veeravalli, Karthik \| Reilly, Dorothea E. \| Grieco, Sung-Hye Antibodies, volume 12, issue 1, pages 16- (2023). 10.3390/antib12010016 Cited by (2) \| Cite \| Source
Methods and compositions for secretion of heterologous polypeptides (patent) Reilly, Dorothea \| Zhou, Yizhou Patent Number: 10435694 (2019) Cite \| Source
Methods and composition for secretion of heterologous polypeptides (patent) Marrichi, Matthew \| Reilly, Dorothea E. Patent Number: 10227416 (2019) Cite \| Source
Methods of producing two chain proteins in bacteria (patent) Giulianotti, James \| Reilly, Dorothea Patent Number: 10112994 (2018) Cite \| Source
Methods of producing two chain proteins in bacteria (patent) Giulianotti, James \| Reilly, Dorothea \| Aurori, Kieran \| Simmons, Laura C. Patent Number: 10066002 (2018) Cite \| Source
High throughput screening identifies novel, cell cycle‐arresting small molecule enhancers of transient protein expression (journal article) Meyer, Hermann‐Josef \| Turincio, Rebecca \| Ng, Shirley \| Li, Juan \| Wilson, Blair \| Chan, Pamela \| Zak, Mark \| Reilly, Dorothea \| Beresini, Maureen H. \| Wong, Athena W. Biotechnology Progress, volume 33, issue 6, pages 1579-1588 (2017). 10.1002/btpr.2517 Cited by (7) \| Cite \| Source
Identification of a novel miRNA that increases transient protein expression in combination with valproic acid (journal article) Meyer, Hermann‐Josef \| Reilly, Dorothea \| Martin, Scott E. \| Wong, Athena W. Biotechnology Progress, volume 33, issue 4, pages 1139-1145 (2017). 10.1002/btpr.2488 Cited by (5) \| Cite \| Source
Enhancing full-length antibody production by signal peptide engineering (journal article) Zhou, Yizhou \| Liu, Peter \| Gan, Yutian \| Sandoval, Wendy \| Katakam, Anand Kumar \| Reichelt, Mike \| Rangell, Linda \| Reilly, Dorothea Microbial Cell Factories, volume 15, issue 1 (2016). 10.1186/s12934-016-0445-3 Cited by (41) \| Cite \| Source \| Open Access
Optimization and automation of an end‐to‐end high throughput microscale transient protein production process (journal article) Bos, Aaron B. \| Luan, Peng \| Duque, Joseph N. \| Reilly, Dorothea \| Harms, Peter D. \| Wong, Athena W. Biotechnology and Bioengineering, volume 112, issue 9, pages 1832-1842 (2015). 10.1002/bit.25601 Cited by (37) \| Cite \| Source
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent (journal article) Merchant, Mark \| Ma, Xiaolei \| Maun, Henry R. \| Zheng, Zhong \| Peng, Jing \| Romero, Mally \| Huang, Arthur \| Yang, Nai-ying \| Nishimura, Merry \| Greve, Joan \| ... \| Yansura, Daniel G. Proceedings of the National Academy of Sciences, volume 110, issue 32 (2013). 10.1073/pnas.1302725110 Cited by (206) \| Cite \| Source \| Open Access
Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies (journal article) Spiess, Christoph \| Merchant, Mark \| Huang, Arthur \| Zheng, Zhong \| Yang, Nai-Ying \| Peng, Jing \| Ellerman, Diego \| Shatz, Whitney \| Reilly, Dorothea \| Yansura, Daniel G \| Scheer, Justin M Nature Biotechnology, volume 31, issue 8, pages 753-758 (2013). 10.1038/nbt.2621 Cited by (232) \| Cite \| Source
Use of an anti‐apoptotic CHO cell line for transient gene expression (journal article) Macaraeg, Nichole F. \| Reilly, Dorothea E. \| Wong, Athena W. Biotechnology Progress, volume 29, issue 4, pages 1050-1058 (2013). 10.1002/btpr.1763 Cited by (24) \| Cite \| Source
Methods and composition for secretion of heterologous polypeptides (patent) Reilly, Dorothea E. \| Marrichi, Matthew Patent Number: 8361744 (2013) Cited by (6) \| Cite \| Source
Enhancement of DNA uptake in FUT8‐deleted CHO cells for transient production of afucosylated antibodies (journal article) Wong, Athena W. \| Baginski, Tomasz K. \| Reilly, Dorothea E. Biotechnology and Bioengineering, volume 106, issue 5, pages 751-763 (2010). 10.1002/bit.22749 Cited by (43) \| Cite \| Source
High-yield expression of human vascular endothelial growth factor VEGF165 in Escherichia coli and purification for therapeutic applications (journal article) Pizarro, Shelly A. \| Gunson, Jane \| Field, Matthew J. \| Dinges, Rachel \| Khoo, Stefanie \| Dalal, Milind \| Lee, Michael \| Kaleas, Kimberly A. \| Moiseff, Kathryn \| Garnick, Susan \| ... \| Schmelzer, Charles H. Protein Expression and Purification, volume 72, issue 2, pages 184-193 (2010). 10.1016/j.pep.2010.03.007 Cited by (23) \| Cite \| Source
Methods and compositions for increasing antibody production (patent) Reilly, Dorothea \| Yansura, Daniel Patent Number: 7655783 (2010) Cited by (7) \| Cite \| Source
Production of Antibodies and Antibody Fragments in Escherichia coli (book chapter) In Antibody Engineering Reilly, Dorothea E. \| Yansura, Daniel G. Springer Berlin Heidelberg (2010) 10.1007/978-3-642-01147-4_26 Cited by (4) \| Cite \| Source
Production of Monoclonal Antibodies in E. coli (book chapter) In Current Trends in Monoclonal Antibody Development and Manufacturing Reilly, Dorothea E. \| Yansura, Daniel G. Springer New York (2010) 10.1007/978-0-387-76643-0_17 Cited by (24) \| Cite \| Source
Methods and compositions for increasing antibody production (patent) Reilly, Dorothea \| Yansura, Daniel Patent Number: 7608429 (2009) Cited by (14) \| Cite \| Source
DNA Internalized via Caveolae Requires Microtubule-dependent, Rab7-independent Transport to the Late Endocytic Pathway for Delivery to the Nucleus (journal article) Wong, Athena W. \| Scales, Suzie J. \| Reilly, Dorothea E. Journal of Biological Chemistry, volume 282, issue 31, pages 22953-22963 (2007). 10.1074/jbc.M611015200 Cited by (57) \| Cite \| Source \| Open Access