Gee-Hong Kuo

ScholarGPS® ID: 92140426314435

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Medicine

Discipline

Cardiology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

1,641

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors (journal article) Xu, Guozhang \| Du, Fuyong \| Kuo, Gee-Hong \| Xu, June Zhi \| Liang, Yin \| Demarest, Keith \| Gaul, Michael D. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 17, pages 127387- (2020). 10.1016/j.bmcl.2020.127387 Cited by (8) \| Cite \| Source
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors (journal article) Xu, Guozhang \| Gaul, Michael D. \| Kuo, Gee-Hong \| Du, Fuyong \| Xu, June Zhi \| Wallace, Nathaniel \| Hinke, Simon \| Kirchner, Thomas \| Silva, Jose \| Huebert, Norman D. \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 28, issue 21, pages 3446-3453 (2018). 10.1016/j.bmcl.2018.09.025 Cited by (9) \| Cite \| Source
Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors (journal article) Kuo, Gee-Hong \| Gaul, Micheal D. \| Liang, Yin \| Xu, June Z. \| Du, Fuyong \| Hornby, Pamela \| Xu, Guozhang \| Qi, Jenson \| Wallace, Nathaniel \| Lee, Seunghun \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 28, issue 7, pages 1182-1187 (2018). 10.1016/j.bmcl.2018.02.057 Cited by (29) \| Cite \| Source
Metabolic tracing of monoacylglycerol acyltransferase-2 activity in vitro and in vivo (journal article) Qi, Jenson \| Lang, Wensheng \| Connelly, Margery A. \| Du, Fuyong \| Liang, Yin \| Caldwell, Gary W. \| Martin, Tonya \| Hansen, Michael K. \| Kuo, Gee-Hong \| Gaul, Michael D. \| ... \| Lee, Seunghun Analytical Biochemistry, volume 524 (2017). 10.1016/j.ab.2016.09.017 Cited by (2) \| Cite \| Source
Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors (journal article) Qi, Jenson \| Masucci, John A. \| Lang, Wensheng \| Connelly, Margery A. \| Caldwell, Gary W. \| Petrounia, Ioanna \| Kirkpatrick, Jennifer \| Barnakov, Alexander N. \| Struble, Geoffrey \| Miller, Robyn \| ... \| Lee, Seunghun SLAS Discovery, volume 22, issue 4, pages 433-439 (2017). 10.1177/2472555217690101 Cited by (2) \| Cite \| Source
ChemInform Abstract: Synthesis of β‐Substituted Cyclic Enones via Phosphonium Salt‐Activated, Palladium‐Catalyzed Cross‐Coupling of Cyclic 1,3‐Diones. (journal article) Yang, Shyh‐Ming \| Kuo, Gee‐Hong \| Gaul, Michael D. \| Murray, William V. ChemInform, volume 47, issue 34 (2016). 10.1002/chin.201634053 Cite \| Source
Synthesis of β-Substituted Cyclic Enones via Phosphonium Salt-Activated, Palladium-Catalyzed Cross-Coupling of Cyclic 1,3-Diones (journal article) Yang, Shyh-Ming \| Kuo, Gee-Hong \| Gaul, Michael D. \| Murray, William V. The Journal of Organic Chemistry, volume 81, issue 8, pages 3464-3469 (2016). 10.1021/acs.joc.6b00317 Cited by (5) \| Cite \| Source
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: Part 2. Pyridazine-based analogs (journal article) Yang, Shyh-Ming \| Tang, Yuting \| Rano, Thomas \| Lu, Huajun \| Kuo, Gee-Hong \| Gaul, Michael D. \| Li, Yaxin \| Ho, George \| Lang, Wensheng \| Conway, James G. \| ... \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 24, issue 5, pages 1437-1441 (2014). 10.1016/j.bmcl.2013.12.075 Cited by (5) \| Cite \| Source
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: Urea-based analogs (journal article) Yang, Shyh-Ming \| Tang, Yuting \| Zhang, Rui \| Lu, Huajun \| Kuo, Gee-Hong \| Gaul, Michael D. \| Li, Yaxin \| Ho, George \| Conway, James G. \| Liang, Yin \| ... \| Murray, William V. Bioorganic & Medicinal Chemistry Letters, volume 23, issue 24, pages 6773-6776 (2013). 10.1016/j.bmcl.2013.09.096 Cited by (5) \| Cite \| Source
Optimization of a pyrazole hit from FBDD into a novel series of indazoles as ketohexokinase inhibitors (journal article) Zhang, Xuqing \| Song, Fengbing \| Kuo, Gee-Hong \| Xiang, Amy \| Gibbs, Alan C. \| Abad, Marta C. \| Sun, Weimei \| Kuo, Lawrence C. \| Sui, Zhihua Bioorganic & Medicinal Chemistry Letters, volume 21, issue 16, pages 4762-4767 (2011). 10.1016/j.bmcl.2011.06.067 Cited by (22) \| Cite \| Source
ChemInform Abstract: An Efficient and Scalable Synthesis of (2R,αS)‐3,4‐Dihydro‐2‐[3‐(1,1,2,2‐tetrafluoroethoxy)phenyl]‐5‐ [3‐(trifluoromethoxy)phenyl] ‐α‐(trifluoromethyl)‐1(2H)‐quinolineethanol: A Potent CETP Inhibitor. (journal article) Wang, Aihua \| Zhang, Yan \| Lu, Songfeng \| Murray, William V. \| Kuo, Gee‐Hong ChemInform, volume 42, issue 14 (2011). 10.1002/chin.201114168 Cite \| Source
An efficient and scalable synthesis of (2 R ,α S )‐3,4‐dihydro‐2‐[3‐(1,1,2,2‐tetrafluoroethoxy)phenyl]‐5‐[3‐(trifluoromethoxy)phenyl]‐α‐(trifluoromethyl)‐1(2 H )‐quinolineethanol: A potent CETP inhibitor (journal article) Wang, Aihua \| Zhang, Yan \| Lu, Songfeng \| Murray, William V. \| Kuo, Gee‐Hong Journal of Heterocyclic Chemistry, volume 47, issue 6, pages 1406-1410 (2010). 10.1002/jhet.488 Cited by (1) \| Cite \| Source
ChemInform Abstract: Synthesis and Discovery of 2,3‐Dihydro‐3,8‐diphenylbenzo[1,4]oxazines as a Novel Class of Potent Cholesteryl Ester Transfer Protein Inhibitors. (journal article) Wang, Aihua \| Prouty, Catherine P. \| Pelton, Patricia D. \| Yong, Maria \| Demarest, Keith T. \| Murray, William V. \| Kuo, Gee‐Hong ChemInform, volume 41, issue 26 (2010). 10.1002/chin.201026173 Cite \| Source
Synthesis and discovery of 2,3-dihydro-3,8-diphenylbenzo[1,4]oxazines as a novel class of potent cholesteryl ester transfer protein inhibitors (journal article) Wang, Aihua \| Prouty, Catherine P. \| Pelton, Patricia D. \| Yong, Maria \| Demarest, Keith T. \| Murray, William V. \| Kuo, Gee-Hong Bioorganic & Medicinal Chemistry Letters, volume 20, issue 4, pages 1432-1435 (2010). 10.1016/j.bmcl.2009.12.096 Cited by (35) \| Cite \| Source
Torcetrapib Produces Endothelial Dysfunction Independent of Cholesteryl Ester Transfer Protein Inhibition (journal article) Connelly, Margery A \| Parry, Tom J \| Giardino, Edward C \| Huang, Zhihong \| Cheung, Wai-man \| Chen, Cailin \| Cools, Frank \| Van der Linde, Henk \| Gallacher, David J \| Kuo, Gee-Hong \| ... \| Damiano, Bruce P Journal of Cardiovascular Pharmacology, volume 55, issue 5, pages 459-468 (2010). 10.1097/FJC.0b013e3181cf03cb Cited by (42) \| Cite \| Source
Improved Asymmetric Synthesis of 3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-α-(trifluoromethyl)-1(2 H )-quinolineethanol, a Potent Cholesteryl Ester Transfer Protein Inhibitor (journal article) Rano, Thomas A. \| Kuo, Gee-Hong Organic Letters, volume 11, issue 13, pages 2812-2815 (2009). 10.1021/ol900639j Cited by (25) \| Cite \| Source
Design and synthesis of potent inhibitors of cholesteryl ester transfer protein (CETP) exploiting a 1,2,3,4-tetrahydroquinoline platform (journal article) Rano, Thomas A. \| Sieber-McMaster, Ellen \| Pelton, Patricia D. \| Yang, Maria \| Demarest, Keith T. \| Kuo, Gee-Hong Bioorganic & Medicinal Chemistry Letters, volume 19, issue 9, pages 2456-2460 (2009). 10.1016/j.bmcl.2009.03.051 Cited by (73) \| Cite \| Source
Design, Synthesis, and Biological Evaluation of (2 R ,α S )-3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-α-(trifluoromethyl)-1(2 H )-quinolineethanol as Potent and Orally Active Cholesteryl Ester Transfer Protein Inh (journal article) Kuo, Gee-Hong \| Rano, Thomas \| Pelton, Patricia \| Demarest, Keith T. \| Gibbs, Alan C. \| Murray, William V. \| Damiano, Bruce P. \| Connelly, Margery A. Journal of Medicinal Chemistry, volume 52, issue 6, pages 1768-1772 (2009). 10.1021/jm801319d Cited by (37) \| Cite \| Source
Discovery and SAR of para-alkylthiophenoxyacetic acids as potent and selective PPARδ agonists (journal article) Zhang, Rui \| DeAngelis, Alan \| Wang, Aihua \| Sieber-McMaster, Ellen \| Li, Xun \| Russell, Ronald \| Pelton, Patricia \| Xu, Jun \| Zhu, Peifang \| Zhou, Lubing \| ... \| Kuo, Gee-Hong Bioorganic & Medicinal Chemistry Letters, volume 19, issue 4, pages 1101-1104 (2009). 10.1016/j.bmcl.2008.12.113 Cited by (11) \| Cite \| Source
Synthesis of a 5-((Aryloxy)methyl)-3-(4-(trifluoromethyl)phenyl)[1,2,4]thiadiazole Derivative: A Promising PPARα,δ Agonist (journal article) Reuman, Michael \| Hu, Zhiyong \| Kuo, Gee-Hong \| Li, Xun \| Russell, Ronald K. \| Shen, Lan \| Youells, Scott \| Zhang, Yongzheng Organic Process Research & Development, volume 11, issue 6, pages 1010-1014 (2007). 10.1021/op700141u Cited by (6) \| Cite \| Source