Simon Charles Goodacre

ScholarGPS® ID: 91837751348502

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Life Sciences

Discipline

Neurosciences

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

1,341

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Heteroaryl estrogen receptor modulators and uses thereof (patent) Labadie, Sharada \| Li, Jun \| Liang, Jun \| Ortwine, Daniel Fred \| Wang, Xiaojing \| Zbieg, Jason \| Zhang, Birong \| Ray, Nicholas Charles \| Goodacre, Simon \| Liao, Jiangpeng Patent Number: 10654867 (2020) Cite \| Source
Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927 (journal article) Labadie, Sharada S. \| Li, Jun \| Blake, Robert A. \| Chang, Jae H. \| Goodacre, Simon \| Hartman, Steven J. \| Liang, Weiling \| Kiefer, James R. \| Kleinheinz, Tracy \| Lai, Tommy \| ... \| Wang, Xiaojing Bioorganic & Medicinal Chemistry Letters, volume 29, issue 16, pages 2090-2093 (2019). 10.1016/j.bmcl.2019.07.013 Cited by (12) \| Cite \| Source
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling (journal article) Zak, Mark \| Hanan, Emily J. \| Lupardus, Patrick \| Brown, David G. \| Robinson, Colin \| Siu, Michael \| Lyssikatos, Joseph P. \| Romero, F. Anthony \| Zhao, Guiling \| Kellar, Terry \| ... \| Johnson, Adam Bioorganic & Medicinal Chemistry Letters, volume 29, issue 12, pages 1522-1531 (2019). 10.1016/j.bmcl.2019.04.008 Cited by (26) \| Cite \| Source
Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma (journal article) Dengler, Hart S. \| Wu, Xiumin \| Peng, Ivan \| Rinderknecht, Cornelia H. \| Kwon, Youngsu \| Suto, Eric \| Kohli, Pawan Bir \| Liimatta, Marya \| Barrett, Kathy \| Lloyd, Julia \| ... \| Ghilardi, Nico Science Translational Medicine, volume 10, issue 468 (2018). 10.1126/scitranslmed.aao2151 Cited by (25) \| Cite \| Source
Heterocyclic estrogen receptor modulators and uses thereof (patent) Labadie, Sharada \| Liang, Jun \| Ortwine, Daniel Fred \| Wang, Xiaojing \| Zhang, Birong \| Smith, Nicholas D. \| Govek, Steven P. \| Kahraman, Mehmet \| Lai, Andiliy G. \| Nagasawa, Johnny Y. \| ... \| Ray, Nicholas Charles Patent Number: 10053451 (2018) Cite \| Source
Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof (patent) Labadie, Sharada \| Liang, Jun \| Ortwine, Daniel Fred \| Wang, Xiaojing \| Zbieg, Jason \| Zhang, Birong \| Goodacre, Simon Charles \| Ray, Nicholas Charles \| Li, Jun Patent Number: 9980947 (2018) Cited by (1) \| Cite \| Source
Triazolopyridine compounds, compositions and methods of use thereof (patent) Ray, Nicholas C. \| Cheng, Yun-Xing \| Edwards, Christine \| Goodacre, Simon C. \| Li, Wei \| Patel, Snahel \| Cartwright, Matthew W. \| Sajad, Mohammed \| Yuen, Po-wai \| Zak, Mark E. Patent Number: 9873709 (2018) Cited by (1) \| Cite \| Source
Estrogen receptor modulators and uses thereof (patent) Liang, Jun \| Ortwine, Daniel Fred \| Wang, Xiaojing \| Govek, Steven P. \| Kahraman, Mehmet \| Nagasawa, Johnny Y. \| Smith, Nicholas D. \| Goodacre, Simon Charles \| Ray, Nicholas Charles Patent Number: 9845291 (2017) Cited by (1) \| Cite \| Source
5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof (patent) Zak, Mark Edward \| Ray, Nicholas Charles \| Goodacre, Simon Charles \| Mendonca, Rohan \| Kellar, Terry \| Cheng, Yun-Xing \| Li, Wei \| Yuen, Po-Wei Patent Number: 9604984 (2017) Cited by (1) \| Cite \| Source
1,7-diazacarbazoles and methods of use (patent) Dyke, Hazel Joan \| Gazzard, Lewis \| Williams, Karen \| Chen, Huifen \| Kintz, Samuel \| Drobnick, Joy \| Lyssikatos, Joseph P. \| Goodacre, Simon \| Macleod, Calum \| Ellwood, Charles Patent Number: 9440976 (2016) Cite \| Source
5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof (patent) Zak, Mark Edward \| Ray, Nicholas Charles \| Goodacre, Simon Charles \| Mendonca, Rohan \| Kellar, Terry \| Cheng, Yun-Xing \| Li, Wei \| Yuen, Po-Wai Patent Number: 9346815 (2016) Cited by (2) \| Cite \| Source
Pyrazolopyridine compounds, compositions and methods of use (patent) Blench, Toby \| Goodacre, Simon \| Lai, Yingjie \| Liang, Jun \| Macleod, Calum \| Magnuson, Steven \| Tsui, Vickie \| Williams, Karen \| Zhang, Birong Patent Number: 9309240 (2016) Cite \| Source
Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1 (journal article) Gazzard, Lewis \| Appleton, Brent \| Chapman, Kerry \| Chen, Huifen \| Clark, Kevin \| Drobnick, Joy \| Goodacre, Simon \| Halladay, Jason \| Lyssikatos, Joseph \| Schmidt, Stephen \| ... \| Malek, Shiva Bioorganic & Medicinal Chemistry Letters, volume 24, issue 24, pages 5704-5709 (2014). 10.1016/j.bmcl.2014.10.063 Cited by (17) \| Cite \| Source
Azabenzothiazole compounds, compositions and methods of use (patent) Blench, Toby Jonathan \| Ellwood, Charles \| Goodacre, Simon Charles \| Lai, Yingjie \| Liang, Jun \| Macleod, Calum \| Magnuson, Steven R. \| Tsui, Vickie H. \| Williams, Karen \| Zhang, Birong Patent Number: 8697708 (2014) Cite \| Source
Diazacarbazoles and methods of use (patent) MacLeod, Calum \| Ellwood, Charles \| Gancia, Emanuela \| Dyke, Hazel Joan \| Chen, Huifen \| Lyssikatos, Joseph \| Williams, Karen \| Gazzard, Lewis J. \| Kintz, Samuel \| Goodacre, Simon Patent Number: 8501765 (2013) Cited by (3) \| Cite \| Source
Janus kinase inhibitor compounds and methods (patent) Zhou, Aihe \| Zhang, Birong \| Liang, Jun \| Williams, Karen \| Robarge, Kirk D. \| Stanley, Mark S. \| Goodacre, Simon Charles \| Magnuson, Steven R. \| Hsiao-Wei Tsui, Vickie \| Lai, Yingjie Patent Number: 8486950 (2013) Cited by (15) \| Cite \| Source
Aza-indolyl compounds and methods of use (patent) Goodacre, Simon Charles \| Williams, Karen \| Price, Stephen \| Dyke, Hazel Joan \| Montana, John Gary \| Stanley, Mark S. \| Bao, Liang \| Lee, Wendy Patent Number: 7855216 (2010) Cited by (2) \| Cite \| Source
Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1 (journal article) Blackaby, Wesley P. \| Lewis, Richard T. \| Thomson, Joanne L. \| Jennings, Andrew S. R. \| Goodacre, Simon C. \| Street, Leslie J. \| MacLeod, Angus M. \| Pike, Andrew \| Wood, Suzanne \| Thomas, Steve \| ... \| Hamill, Terence G. ACS Medicinal Chemistry Letters, volume 1, issue 7, pages 350-354 (2010). 10.1021/ml1001085 Cited by (19) \| Cite \| Source \| Open Access
Optimisation of a series of potent, selective and orally bioavailable GlyT1 inhibitors (journal article) Thomson, Joanne L. \| Blackaby, Wesley P. \| Jennings, Andrew S.R. \| Goodacre, Simon C. \| Pike, Andrew \| Thomas, Steve \| Brown, Terry A. \| Smith, Alison \| Pillai, Gopalan \| Street, Leslie J. \| Lewis, Richard T. Bioorganic & Medicinal Chemistry Letters, volume 19, issue 8, pages 2235-2239 (2009). 10.1016/j.bmcl.2009.02.102 Cited by (13) \| Cite \| Source
Imidazopyrazinones as GABA-A receptor anxiolytics (patent) Carling, William Robert \| Castro Pineiro, Jose Luis \| Goodacre, Simon Charles \| Hallett, David James \| Street, Leslie Joseph Patent Number: 7485640 (2009) Cite \| Source