Shumin Tan

ScholarGPS® ID: 91775303529575

Affiliation

Tufts University, Medford and Somerville, United States

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Tuberculosis | Mycobacterium Tuberculosis | Pathogen | Helicobacter Pylori

Metrics Summary

Publication Count

Predicted Citations

1,920

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Mycobacterium tuberculosis response to cholesterol is integrated with environmental pH and potassium levels via a lipid metabolism regulator (journal article) Chen, Yue \| MacGilvary, Nathan J. \| Tan, Shumin PLOS Genetics, volume 20, issue 1, pages e1011143- (2024). 10.1371/journal.pgen.1011143 Cited by (1) \| Cite \| Source
Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin (journal article) Xu, Shuying \| Mo, Devons \| Rizvi, Fatima Z. \| Rosa, Juan P. \| Ruiz, Jorge \| Tan, Shumin \| Tweten, Rodney K. \| Leong, John M. \| Adams, Walter Infection and Immunity, volume 91, issue 9 (2023). 10.1128/iai.00213-23 Cited by (3) \| Cite \| Source
Shining a light on bacterial environmental cue integration and its relation to metabolism (journal article) Chen, Yue \| Quirk, Natalia F. \| Tan, Shumin Molecular Microbiology, volume 120, issue 1, pages 71-74 (2023). 10.1111/mmi.15065 Cited by (1) \| Cite \| Source
Liquid chromatography-mass spectrometry-based protocol to measure drug accumulation in Mycobacterium tuberculosis and its host cell (journal article) Ahn, Yong-Mo \| Lavin, Richard C. \| Tan, Shumin \| Freundlich, Joel S. STAR Protocols, volume 4, issue 1, pages 101971- (2023). 10.1016/j.xpro.2022.101971 Cite \| Source
An AP ‐3‐dependent pathway directs phagosome fusion with Rab8 and Rab11 vesicles involved in TLR2 signaling (journal article) Petnicki‐Ocwieja, Tanja \| Sharma, Bijaya \| Powale, Urmila \| Pathak, Devesh \| Tan, Shumin \| Hu, Linden T. Traffic, volume 23, issue 12, pages 558-567 (2022). 10.1111/tra.12870 Cited by (1) \| Cite \| Source
PrrA modulates Mycobacterium tuberculosis response to multiple environmental cues and is critically regulated by serine/threonine protein kinases (journal article) Giacalone, David \| Yap, Rochelle E. \| Ecker, Alwyn M. V. \| Tan, Shumin PLOS Genetics, volume 18, issue 8, pages e1010331- (2022). 10.1371/journal.pgen.1010331 Cited by (10) \| Cite \| Source
Rv0500A is a transcription factor that links Mycobacterium tuberculosis environmental response with division and impacts host colonization (journal article) Kevorkian, Yuzo L. \| MacGilvary, Nathan J. \| Giacalone, David \| Johnson, Calvin \| Tan, Shumin Molecular Microbiology, volume 117, issue 5, pages 1048-1062 (2022). 10.1111/mmi.14886 Cited by (3) \| Cite \| Source
Spatial relationships of intra-lesion heterogeneity in Mycobacterium tuberculosis microenvironment, replication status, and drug efficacy (journal article) Lavin, Richard C. \| Tan, Shumin PLOS Pathogens, volume 18, issue 3, pages e1010459- (2022). 10.1371/journal.ppat.1010459 Cited by (14) \| Cite \| Source
Targeting Mycobacterium tuberculosis response to environmental cues for the development of effective antitubercular drugs (journal article) Lavin, Richard C. \| Johnson, Calvin \| Ahn, Yong-Mo \| Kremiller, Kyle M. \| Sherwood, Matthew \| Patel, Jimmy S. \| Pan, Yan \| Russo, Riccardo \| MacGilvary, Nathan J. \| Giacalone, David \| ... \| Tan, Shumin PLOS Biology, volume 19, issue 7, pages e3001355- (2021). 10.1371/journal.pbio.3001355 Cited by (10) \| Cite \| Source
Abundant Monovalent Ions as Environmental Signposts for Pathogens during Host Colonization (journal article) Tan, Shumin Infection and Immunity, volume 89, issue 4 (2021). 10.1128/IAI.00641-20 Cited by (6) \| Cite \| Source
Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers (journal article) Fasciano, Alyssa C. \| Dasanayake, Gaya S. \| Estes, Mary K. \| Zachos, Nicholas C. \| Breault, David T. \| Isberg, Ralph R. \| Tan, Shumin \| Mecsas, Joan Gut Microbes, volume 13, issue 1 (2021). 10.1080/19490976.2021.1988390 Cited by (13) \| Cite \| Source
Exploiting Fluorescent Proteins to Understand Mycobacterium tuberculosis Biology (book chapter) In Mycobacteria Protocols Giacalone, David \| Huang, Lu \| Tan, Shumin Springer US (2021) 10.1007/978-1-0716-1460-0_17 Cited by (4) \| Cite \| Source
Yersinia pseudotuberculosis YopH targets SKAP2-dependent and independent signaling pathways to block neutrophil antimicrobial mechanisms during infection (journal article) Shaban, Lamyaa \| Nguyen, Giang T. \| Mecsas-Faxon, Benjamin D. \| Swanson, Kenneth D. \| Tan, Shumin \| Mecsas, Joan PLOS Pathogens, volume 16, issue 5, pages e1008576- (2020). 10.1371/journal.ppat.1008576 Cited by (14) \| Cite \| Source
Adjunctive Host-Directed Therapy With Statins Improves Tuberculosis-Related Outcomes in Mice (journal article) Dutta, Noton K \| Bruiners, Natalie \| Zimmerman, Matthew D \| Tan, Shumin \| Dartois, Véronique \| Gennaro, Maria L \| Karakousis, Petros C The Journal of Infectious Diseases (2020). 10.1093/infdis/jiz517 Cited by (52) \| Cite \| Source
mSphere of Influence: Clearing a Path for High-Resolution Visualization of Host-Pathogen Interactions In Vivo (journal article) Tan, Shumin mSphere, volume 4, issue 4 (2019). 10.1128/mSphere.00308-19 Cite \| Source
High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach (journal article) Fung, Connie \| Tan, Shumin \| Nakajima, Mifuyu \| Skoog, Emma C. \| Camarillo-Guerrero, Luis Fernando \| Klein, Jessica A. \| Lawley, Trevor D. \| Solnick, Jay V. \| Fukami, Tadashi \| Amieva, Manuel R. PLOS Biology, volume 17, issue 5, pages e3000231- (2019). 10.1371/journal.pbio.3000231 Cited by (64) \| Cite \| Source
Potassium response and homeostasis in Mycobacterium tuberculosis modulates environmental adaptation and is important for host colonization (journal article) MacGilvary, Nathan J. \| Kevorkian, Yuzo L. \| Tan, Shumin PLOS Pathogens, volume 15, issue 2, pages e1007591- (2019). 10.1371/journal.ppat.1007591 Cited by (36) \| Cite \| Source
The Deconstructed Granuloma: A Complex High-Throughput Drug Screening Platform for the Discovery of Host-Directed Therapeutics Against Tuberculosis (journal article) Huang, Lu \| Kushner, Nicole L. \| Theriault, Monique E. \| Pisu, Davide \| Tan, Shumin \| McNamara, Case W. \| Petrassi, H. Mike \| Russell, David G. \| Brown, Amanda C. Frontiers in Cellular and Infection Microbiology, volume 8 (2018). 10.3389/fcimb.2018.00275 Cited by (22) \| Cite \| Source \| Open Access
Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny (journal article) Huang, Lu \| Nazarova, Evgeniya V. \| Tan, Shumin \| Liu, Yancheng \| Russell, David G. Journal of Experimental Medicine, volume 215, issue 4, pages 1135-1152 (2018). 10.1084/jem.20172020 Cited by (335) \| Cite \| Source \| Open Access
Fluorescent Mycobacterium tuberculosis reporters: illuminating host–pathogen interactions (journal article) MacGilvary, Nathan J \| Tan, Shumin Pathogens and Disease, volume 76, issue 3 (2018). 10.1093/femspd/fty017 Cited by (29) \| Cite \| Source \| Open Access

Title	Investigators	Year	Cost	Agency
An imaging approach to understanding the impact of heterogeneity in microenvironments and lesion properties during Mycobacterium tuberculosis infection	TAN, Shumin	2020	$204,950	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Mycobacterium tuberculosis environmental signal integration: single cell in vivo understanding of its influence on infection heterogeneity and treatment efficacy	TAN, Shumin	2020	$608,229	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
An imaging approach to understanding the impact of heterogeneity in microenvironments and lesion properties during Mycobacterium tuberculosis infection	TAN, Shumin	2019	$246,200	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Mycobacterium tuberculosis environmental signal integration: single cell in vivo understanding of its influence on infection heterogeneity and treatment efficacy	TAN, Shumin	2019	$620,485	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Bacterial Sensing and Response to Chloride as a Novel Tuberculosis Drug Target	TAN, Shumin	2017	$249,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Bacterial Sensing and Response to Chloride as a Novel Tuberculosis Drug Target	TAN, Shumin	2016	$249,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Bacterial Sensing and Response to Chloride as a Novel Tuberculosis Drug Target	TAN, Shumin	2015	$103,648	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES