Lena Gerwick

ScholarGPS® ID: 91152924587950

Affiliation
University of California, San Diego, San Diego, United States
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Oceanography and Limnology
Top Specialties
Natural Product | Rainbow Trout | Genomics | Biosynthesis | Acute-phase Protein | Mass Spectrometry | Bacteria | Chemical Biology | Enzyme
Metrics Summary
Publication Count
88
Predicted Citations
5,590
Predicted h-index
41
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with Candida albicans (journal article)
Ngo, Thuan-Ethan | Ecker, Andrew | Ryu, Byeol | Guild, Aurora | Remmel, Ariana | Boudreau, Paul D. | Alexander, Kelsey L. | Naman, C. Benjamin | Glukhov, Evgenia | Avalon, Nicole E. | ... | Gerwick, William H.
ACS Chemical Biology, volume 19, issue 3, pages 619-628 (2024).
10.1021/acschembio.3c00391
Cite | Source
NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters (journal article)
Leão, Tiago F | Wang, Mingxun | da Silva, Ricardo | Gurevich, Alexey | Bauermeister, Anelize | Gomes, Paulo Wender P | Brejnrod, Asker | Glukhov, Evgenia | Aron, Allegra T | Louwen, Joris J R | ... | Dorrestein, Pieter C
PNAS Nexus, volume 1, issue 5 (2022).
10.1093/pnasnexus/pgac257
Cited by (8) | Cite | Source
Heterologous Expression in Anabaena of the Columbamide Pathway from the Cyanobacterium Moorena bouillonii and Production of New Analogs (journal article)
Taton, Arnaud | Rohrer, Sebastian | Diaz, Brienna | Reher, Raphael | Caraballo Rodriguez, Andres Mauricio | Pierce, Marsha L. | Dorrestein, Pieter C. | Gerwick, Lena | Gerwick, William H. | Golden, James W.
ACS Chemical Biology, volume 17, issue 7, pages 1910-1923 (2022).
10.1021/acschembio.2c00347
Cited by (7) | Cite | Source
Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium (journal article)
Demirkiran, Ozlem | Almaliti, Jehad | Leão, Tiago | Navarro, Gabriel | Byrum, Tara | Valeriote, Frederick A. | Gerwick, Lena | Gerwick, William H.
Journal of Natural Products, volume 84, issue 8, pages 2081-2093 (2021).
10.1021/acs.jnatprod.0c01383
Cited by (4) | Cite | Source
Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2 (journal article)
Christy, Mitchell P. | Uekusa, Yoshinori | Gerwick, Lena | Gerwick, William H.
Journal of Natural Products, volume 84, issue 1, pages 161-182 (2021).
10.1021/acs.jnatprod.0c00968
Cited by (37) | Cite | Source
A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria (journal article)
Leão, Tiago | Wang, Mingxun | Moss, Nathan | da Silva, Ricardo | Sanders, Jon | Nurk, Sergey | Gurevich, Alexey | Humphrey, Gregory | Reher, Raphael | Zhu, Qiyun | ... | Gerwick, Lena
Marine Drugs, volume 19, issue 1, pages 20- (2021).
10.3390/md19010020
Cited by (22) | Cite | Source
Heterologous Expression of Cryptomaldamide in a Cyanobacterial Host (journal article)
Taton, Arnaud | Ecker, Andrew | Diaz, Brienna | Moss, Nathan A. | Anderson, Brooke | Reher, Raphael | Leão, Tiago F. | Simkovsky, Ryan | Dorrestein, Pieter C. | Gerwick, Lena | ... | Golden, James W.
ACS Synthetic Biology, volume 9, issue 12, pages 3364-3376 (2020).
10.1021/acssynbio.0c00431
Cited by (25) | Cite | Source
An anti-inflammatory isoflavone from soybean inoculated with a marine fungus Aspergillus terreus C23-3 (journal article)
Yang, Jing-Ming | Liu, Ya-Yue | Yang, Wen-Cong | Ma, Xiao-Xiang | Nie, Ying-Ying | Glukhov, Evgenia | Gerwick, Lena | Gerwick, William H | Lei, Xiao-Ling | Zhang, Yi
Bioscience, Biotechnology, and Biochemistry, volume 84, issue 8, pages 1546-1553 (2020).
10.1080/09168451.2020.1764838
Cited by (6) | Cite | Source
Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking (journal article)
Li, Yueying | Yu, Hao-Bing | Zhang, Yi | Leao, Tiago | Glukhov, Evgenia | Pierce, Marsha L. | Zhang, Chen | Kim, Hyunwoo | Mao, Huanru Henry | Fang, Fang | ... | Gerwick, William H.
Journal of Natural Products, volume 83, issue 3, pages 617-625 (2020).
10.1021/acs.jnatprod.9b01019
Cited by (23) | Cite | Source
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities (journal article)
Cao, Liu | Gurevich, Alexey | Alexander, Kelsey L. | Naman, C. Benjamin | Leão, Tiago | Glukhov, Evgenia | Luzzatto-Knaan, Tal | Vargas, Fernando | Quinn, Robby | Bouslimani, Amina | ... | Mohimani, Hosein
Cell Systems, volume 9, issue 6, pages 600-608.e4 (2019).
10.1016/j.cels.2019.09.004
Cited by (46) | Cite | Source
Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens (journal article)
Yu, Hao-Bing | Glukhov, Evgenia | Li, Yueying | Iwasaki, Arihiro | Gerwick, Lena | Dorrestein, Pieter C. | Jiao, Bing-Hua | Gerwick, William H.
Journal of Natural Products, volume 82, issue 9, pages 2608-2619 (2019).
10.1021/acs.jnatprod.9b00549
Cited by (24) | Cite | Source
Nature's Combinatorial Biosynthesis Produces Vatiamides A–F (journal article)
Moss, Nathan A. | Seiler, Grant | Leão, Tiago F. | Castro‐Falcón, Gabriel | Gerwick, Lena | Hughes, Chambers C. | Gerwick, William H.
Angewandte Chemie, volume 131, issue 27, pages 9125-9129 (2019).
10.1002/ange.201902571
Cited by (4) | Cite | Source
Nature's Combinatorial Biosynthesis Produces Vatiamides A–F (journal article)
Moss, Nathan A. | Seiler, Grant | Leão, Tiago F. | Castro‐Falcón, Gabriel | Gerwick, Lena | Hughes, Chambers C. | Gerwick, William H.
Angewandte Chemie International Edition, volume 58, issue 27, pages 9027-9031 (2019).
10.1002/anie.201902571
Cited by (33) | Cite | Source
Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta (journal article)
Moss, Nathan A. | Leão, Tiago | Rankin, Michael R. | McCullough, Tyler M. | Qu, Pingping | Korobeynikov, Anton | Smith, Janet L. | Gerwick, Lena | Gerwick, William H.
ACS Chemical Biology, volume 13, issue 12, pages 3385-3395 (2018).
10.1021/acschembio.8b00910
Cited by (23) | Cite | Source
Biosynthesis of t -Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module (journal article)
Skiba, Meredith A. | Sikkema, Andrew P. | Moss, Nathan A. | Lowell, Andrew N. | Su, Min | Sturgis, Rebecca M. | Gerwick, Lena | Gerwick, William H. | Sherman, David H. | Smith, Janet L.
ACS Chemical Biology, volume 13, issue 6, pages 1640-1650 (2018).
10.1021/acschembio.8b00252
Cited by (18) | Cite | Source
Novel Marine Compounds Modulate Mitochondrial Function in H9c2 Cells: Potential New Pharmaceutical Targets to Control Cardiac Metabolism (journal article)
Warmbrunn, Moritz Valerian | Schilling, Jan M. | Dhanani, Mehul | Glukhov, Evgenia | Gerwick, Lena G. | Gerwick, William H. | Patel, Hemal H.
The FASEB Journal, volume 32, issue S1 (2018).
10.1096/fasebj.2018.32.1_supplement.702.1
Cite | Source
Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway (journal article)
Mascuch, Samantha J. | Boudreau, Paul D. | Carland, Tristan M. | Pierce, N. Tessa | Olson, Joshua | Hensler, Mary E. | Choi, Hyukjae | Campanale, Joseph | Hamdoun, Amro | Nizet, Victor | ... | Gerwick, Lena
Journal of Natural Products, volume 81, issue 3, pages 506-514 (2018).
10.1021/acs.jnatprod.7b00734
Cited by (25) | Cite | Source
Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp. (journal article)
Tao, Yiwen | Li, Pinglin | Zhang, Daojing | Glukhov, Evgenia | Gerwick, Lena | Zhang, Chen | Murray, Thomas F. | Gerwick, William H.
The Journal of Organic Chemistry, volume 83, issue 6, pages 3034-3046 (2018).
10.1021/acs.joc.8b00028
Cited by (13) | Cite | Source | Open Access
Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert -Butyl Group (journal article)
Shao, Chang-Lun | Mou, Xiao-Feng | Cao, Fei | Spadafora, Carmenza | Glukhov, Evgenia | Gerwick, Lena | Wang, Chang-Yun | Gerwick, William H.
Journal of Natural Products, volume 81, issue 1, pages 211-215 (2018).
10.1021/acs.jnatprod.7b00917
Cited by (30) | Cite | Source
Collection, Culturing, and Genome Analyses of Tropical Marine Filamentous Benthic Cyanobacteria (book chapter)
In Marine Enzymes and Specialized Metabolism - Part A
Moss, Nathan A. | Leao, Tiago | Glukhov, Evgenia | Gerwick, Lena | Gerwick, William H.
Elsevier (2018)
10.1016/bs.mie.2018.02.014
Cited by (8) | Cite | Source