Mark L. Paddock

ScholarGPS® ID: 90628052367828

Affiliation
University of California, San Diego, San Diego, United States
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Bacteria | Photosynthesis | Electron Transfer | Biophysics | Spectroscopy | Mutation | Fourier-transform Infrared Spectroscopy | Membrane Protein | Cancer | Carboxylic Acid | Diabetes | Energy
Metrics Summary
Publication Count
115
Predicted Citations
6,324
Predicted h-index
45
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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A Combined Computational and Genetic Approach Uncovers Network Interactions of the Cyanobacterial Circadian Clock (journal article)
Boyd, Joseph S. | Cheng, Ryan R. | Paddock, Mark L. | Sancar, Cigdem | Morcos, Faruck | Golden, Susan S.
Journal of Bacteriology, volume 198, issue 18, pages 2439-2447 (2016).
10.1128/JB.00235-16
Cited by (14) | Cite | Source | Open Access
The NEET Proteins Mediate Iron-Sulfur Cluster Transport from the Mitochondria to Cytosolic Proteins (journal article)
Lipper, Colin H. | Paddock, Mark L. | Nechushtai, Rachel | Jennings, Patricia A.
Biophysical Journal, volume 110, issue 3, pages 549a- (2016).
10.1016/j.bpj.2015.11.2938
Cite | Source | Open Access
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells (journal article)
Holt, Sarah H. | Darash-Yahana, Merav | Sohn, Yang Sung | Song, Luhua | Karmi, Ola | Tamir, Sagi | Michaeli, Dorit | Luo, Yuting | Paddock, Mark L. | Jennings, Patricia A. | ... | Mittler, Ron
Journal of Cell Science, volume 129, issue 1, pages 155-165 (2016).
10.1242/jcs.178293
Cited by (31) | Cite | Source | Open Access
Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis (journal article)
Lipper, Colin H. | Paddock, Mark L. | Onuchic, José N. | Mittler, Ron | Nechushtai, Rachel | Jennings, Patricia A.
PLOS ONE, volume 10, issue 10, pages e0139699- (2015).
10.1371/journal.pone.0139699
Cited by (73) | Cite | Source | Open Access
Structure–function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease (journal article)
Tamir, Sagi | Paddock, Mark L. | Darash-Yahana-Baram, Merav | Holt, Sarah H. | Sohn, Yang Sung | Agranat, Lily | Michaeli, Dorit | Stofleth, Jason T. | Lipper, Colin H. | Morcos, Faruck | ... | Nechushtai, Rachel
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, volume 1853, issue 6, pages 1294-1315 (2015).
10.1016/j.bbamcr.2014.10.014
Cited by (125) | Cite | Source | Open Access
The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer (journal article)
Bai, Fang | Morcos, Faruck | Sohn, Yang-Sung | Darash-Yahana, Merav | Rezende, Celso O. | Lipper, Colin H. | Paddock, Mark L. | Song, Luhua | Luo, Yuting | Holt, Sarah H. | ... | Nechushtai, Rachel
Proceedings of the National Academy of Sciences, volume 112, issue 12, pages 3698-3703 (2015).
10.1073/pnas.1502960112
Cited by (64) | Cite | Source | Open Access
High-Throughput and Quantitative Approaches for Measuring Circadian Rhythms in Cyanobacteria Using Bioluminescence (book chapter)
In Circadian Rhythms and Biological Clocks, Part A
Shultzaberger, Ryan K. | Paddock, Mark L. | Katsuki, Takeo | Greenspan, Ralph J. | Golden, Susan S.
Elsevier (2015)
10.1016/bs.mie.2014.10.010
Cited by (2) | Cite | Source | Open Access
A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties (journal article)
Tamir, Sagi | Eisenberg-Domovich, Yael | Conlan, Andrea R. | Stofleth, Jason T. | Lipper, Colin H. | Paddock, Mark L. | Mittler, Ron | Jennings, Patricia A. | Livnah, Oded | Nechushtai, Rachel
Acta Crystallographica Section D Biological Crystallography, volume 70, issue 6, pages 1572-1578 (2014).
10.1107/S1399004714005458
Cited by (30) | Cite | Source | Open Access
Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1 (journal article)
Tamir, Sagi | Rotem-Bamberger, Shahar | Katz, Chen | Morcos, Faruck | Hailey, Kendra L. | Zuris, John A. | Wang, Charles | Conlan, Andrea R. | Lipper, Colin H. | Paddock, Mark L. | ... | Nechushtai, Rachel
Proceedings of the National Academy of Sciences, volume 111, issue 14, pages 5177-5182 (2014).
10.1073/pnas.1403770111
Cited by (51) | Cite | Source | Open Access
Active output state of the Synechococcus Kai circadian oscillator (journal article)
Paddock, Mark L. | Boyd, Joseph S. | Adin, Dawn M. | Golden, Susan S.
Proceedings of the National Academy of Sciences, volume 110, issue 40 (2013).
10.1073/pnas.1315170110
Cited by (26) | Cite | Source | Open Access
NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth (journal article)
Sohn, Yang-Sung | Tamir, Sagi | Song, Luhua | Michaeli, Dorit | Matouk, Imad | Conlan, Andrea R. | Harir, Yael | Holt, Sarah H. | Shulaev, Vladimir | Paddock, Mark L. | ... | Mittler, Ron
Proceedings of the National Academy of Sciences, volume 110, issue 36, pages 14676-14681 (2013).
10.1073/pnas.1313198110
Cited by (164) | Cite | Source | Open Access
Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs (journal article)
Tamir, Sagi | Zuris, John A. | Agranat, Lily | Lipper, Colin H. | Conlan, Andrea R. | Michaeli, Dorit | Harir, Yael | Paddock, Mark L. | Mittler, Ron | Cabantchik, Zvi Ioav | ... | Nechushtai, Rachel
PLoS ONE, volume 8, issue 5, pages e61202- (2013).
10.1371/journal.pone.0061202
Cited by (41) | Cite | Source | Open Access
Allosteric control in a metalloprotein dramatically alters function (journal article)
Baxter, Elizabeth Leigh | Zuris, John A. | Wang, Charles | Vo, Phu Luong T. | Axelrod, Herbert L. | Cohen, Aina E. | Paddock, Mark L. | Nechushtai, Rachel | Onuchic, Jose N. | Jennings, Patricia A.
Proceedings of the National Academy of Sciences, volume 110, issue 3, pages 948-953 (2013).
10.1073/pnas.1208286110
Cited by (22) | Cite | Source | Open Access
Characterization of Arabidopsis NEET Reveals an Ancient Role for NEET Proteins in Iron Metabolism (journal article)
Nechushtai, Rachel | Conlan, Andrea R. | Harir, Yael | Song, Luhua | Yogev, Ohad | Eisenberg-Domovich, Yael | Livnah, Oded | Michaeli, Dorit | Rosen, Rachel | Ma, Vincent | ... | Mittler, Ron
The Plant Cell, volume 24, issue 5, pages 2139-2154 (2012).
10.1105/tpc.112.097634
Cited by (82) | Cite | Source | Open Access
NADPH Inhibits [2Fe-2S] Cluster Protein Transfer from Diabetes Drug Target MitoNEET to an Apo-acceptor Protein (journal article)
Zuris, John A. | Ali, Syed S. | Yeh, Howard | Nguyen, Tung A. | Nechushtai, Rachel | Paddock, Mark L. | Jennings, Patricia A.
Journal of Biological Chemistry, volume 287, issue 15, pages 11649-11655 (2012).
10.1074/jbc.M111.319731
Cited by (29) | Cite | Source | Open Access
Reduced Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Blocks Transfer of [2Fe-2S] Clusters from MitoNEET to an Apo-Acceptor Protein (journal article)
Zuris, John A. | Ali, Syed S. | Yeh, Howard | Nguyen, Tung A. | Nechushtai, Rachel | Paddock, Mark L. | Jennings, Patricia A.
Biophysical Journal, volume 102, issue 3, pages 459a- (2012).
10.1016/j.bpj.2011.11.2518
Cite | Source | Open Access
The Interaction Between Cisd2 and Bcl Proteins at a Non-BH3 Domain Binding Site (journal article)
Conlan, Andrea R. | Zuris, John A. | Paddock, Mark L. | Katz, Chen | Tamir, Sagi | Rotem-Bamberger, Shahar | Friedler, Assaf | Nechushtai, Rachel | Jennings, Patricia A.
Biophysical Journal, volume 102, issue 3, pages 258a-259a (2012).
10.1016/j.bpj.2011.11.1425
Cite | Source | Open Access
The Structure of an Aldehyde Decarbonylase from Prochlorococcus Marinus Implicated in Biofuel Synthesis Indicates an Octadecanoic Acid Ligand Coordinated to a Di-Iron Catalytic Center∗ (journal article)
Axelrod, Herbert L. | Paddock, Mark L. | Chiu, Hsiu-Ju | Miller, Mitchell M. | Deacon, Ashley M. | Wilson, Ian A.
Biophysical Journal, volume 102, issue 3, pages 271a- (2012).
10.1016/j.bpj.2011.11.1493
Cited by (1) | Cite | Source | Open Access
Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein (journal article)
Zuris, John A. | Harir, Yael | Conlan, Andrea R. | Shvartsman, Maya | Michaeli, Dorit | Tamir, Sagi | Paddock, Mark L. | Onuchic, José N. | Mittler, Ron | Cabantchik, Zvi Ioav | ... | Nechushtai, Rachel
Proceedings of the National Academy of Sciences, volume 108, issue 32, pages 13047-13052 (2011).
10.1073/pnas.1109986108
Cited by (112) | Cite | Source | Open Access
Mutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environment (journal article)
Conlan, Andrea R. | Paddock, Mark L. | Homer, Christina | Axelrod, Herbert L. | Cohen, Aina E. | Abresch, Edward C. | Zuris, John A. | Nechushtai, Rachel | Jennings, Patricia A.
Acta Crystallographica Section D Biological Crystallography, volume 67, issue 6, pages 516-523 (2011).
10.1107/S0907444911011577
Cited by (23) | Cite | Source | Open Access