Scott B. Ficarro

ScholarGPS® ID: 88932730895467

Affiliation

Dana-Farber Cancer Institute, Boston, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Metrics Summary

Publication Count

132

Predicted Citations

16,635

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality (journal article) Li, Zhengnian \| Jiang, Jie \| Ficarro, Scott B. \| Beyett, Tyler S. \| To, Ciric \| Tavares, Isidoro \| Zhu, Yingde \| Li, Jiaqi \| Eck, Michael J. \| Jänne, Pasi A. \| ... \| Gray, Nathanael S. ACS Central Science, volume 10, issue 6, pages 1156-1166 (2024). 10.1021/acscentsci.3c01245 Cited by (1) \| Cite \| Source
APIR: Aggregating Universal Proteomics Database Search Algorithms for Peptide Identification with FDR Control (journal article) Chen, Yiling Elaine \| Ge, Xinzhou \| Woyshner, Kyla \| McDermott, MeiLu \| Manousopoulou, Antigoni \| Ficarro, Scott B \| Marto, Jarrod A \| Li, Kexin \| Wang, Leo David \| Li, Jingyi Jessica Genomics, Proteomics & Bioinformatics (2024). 10.1093/gpbjnl/qzae042 Cite \| Source
ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases (journal article) Li, Zhengnian \| Lu, Wenchao \| Beyett, Tyler S. \| Ficarro, Scott B. \| Jiang, Jie \| Tse, Jason \| Kim, Audrey Yong-Ju \| Marto, Jarrod A. \| Che, Jianwei \| Jänne, Pasi A. \| ... \| Gray, Nathanael S. Journal of Medicinal Chemistry, volume 67, issue 4, pages 2837-2848 (2024). 10.1021/acs.jmedchem.3c01891 Cited by (1) \| Cite \| Source
1H, 13C and 15N backbone and sidechain assignment of the Burkholderia mallei acyl carrier protein (journal article) Matosin, Srdan \| Fischer, Patrick D. \| Droemer, Maxim A. \| Baggs, Eric \| Chowdhury, Abu Sayeed \| Tavares, Isidoro \| Ficarro, Scott B. \| Warner, Lisa Rose \| Arthanari, Haribabu \| Nagarajan, Rajesh Biomolecular NMR Assignments, volume 17, issue 2, pages 167-171 (2023). 10.1007/s12104-023-10136-4 Cite \| Source
A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex (journal article) Chen, Han \| Lye, Ming F. \| Gorgulla, Christoph \| Ficarro, Scott B. \| Cuny, Gregory D. \| Scott, David A. \| Wu, Fan \| Rothlauf, Paul W. \| Wang, Xiaoou \| Fernandez, Rosio \| ... \| Coen, Donald M. PLOS Pathogens, volume 19, issue 11, pages e1011781- (2023). 10.1371/journal.ppat.1011781 Cited by (1) \| Cite \| Source
Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange (journal article) Cruite, Justin T. \| Nowak, Radosław P. \| Donovan, Katherine A. \| Ficarro, Scott B. \| Huang, Huang \| Liu, Hu \| Liu, Yingpeng \| Marto, Jarrod A. \| Metivier, Rebecca J. \| Fischer, Eric S. \| Jones, Lyn H. ACS Medicinal Chemistry Letters, volume 14, issue 11, pages 1576-1581 (2023). 10.1021/acsmedchemlett.3c00371 Cited by (2) \| Cite \| Source
Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia (journal article) Casirati, Gabriele \| Cosentino, Andrea \| Mucci, Adele \| Mahmoud, Mohammed S \| Ugarte Zabala, Iratxe \| Zeng, Jing \| Ficarro, Scott \| Klatt, Denise \| Brendel, Christian \| Rambaldi, Alessandro \| ... \| Genovese, Pietro Blood, volume 142, issue Supplement 1, pages 7130-7130 (2023). 10.1182/blood-2023-189980 Cite \| Source
Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead (journal article) Nowak, Radosław P. \| Ragosta, Leah \| Huerta, Fidel \| Liu, Hu \| Ficarro, Scott B. \| Cruite, Justin T. \| Metivier, Rebecca J. \| Donovan, Katherine A. \| Marto, Jarrod A. \| Fischer, Eric S. \| ... \| Jones, Lyn H. RSC Chemical Biology, volume 4, issue 11, pages 906-912 (2023). 10.1039/D3CB00103B Cited by (6) \| Cite \| Source
237 Epitope engineered hematopoietic stem cells to enable multi-specificity CAR-T cells for acute myeloid leukemia (conference) Casirati, Gabriele \| Cosentino, Andrea \| Mucci, Adele \| Mahmoud, Mohammed S \| Zabala, Iratxe Ugarte \| Zeng, Jing \| Klatt, Denise \| Brendel, Christian \| Ritz, Jerome \| Ficarro, Scott \| ... \| Genovese, Pietro SITC 38th Annual Meeting (SITC 2023) Abstracts (2023) 10.1136/jitc-2023-SITC2023.0237 Cite \| Source
Epitope editing enables targeted immunotherapy of acute myeloid leukaemia (journal article) Casirati, Gabriele \| Cosentino, Andrea \| Mucci, Adele \| Salah Mahmoud, Mohammed \| Ugarte Zabala, Iratxe \| Zeng, Jing \| Ficarro, Scott B. \| Klatt, Denise \| Brendel, Christian \| Rambaldi, Alessandro \| ... \| Genovese, Pietro Nature, volume 621, issue 7978, pages 404-414 (2023). 10.1038/s41586-023-06496-5 Cited by (27) \| Cite \| Source
Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway (journal article) Wei, Peng \| Bott, Alex J. \| Cluntun, Ahmad A. \| Morgan, Jeffrey T. \| Cunningham, Corey N. \| Schell, John C. \| Ouyang, Yeyun \| Ficarro, Scott B. \| Marto, Jarrod A. \| Danial, Nika N. \| ... \| Rutter, Jared Science Advances, volume 8, issue 39 (2022). 10.1126/sciadv.abq0117 Cited by (9) \| Cite \| Source
Cereblon covalent modulation through structure-based design of histidine targeting chemical probes (journal article) Cruite, Justin T. \| Dann, Geoffrey P. \| Che, Jianwei \| Donovan, Katherine A. \| Ferrao, Silas \| Ficarro, Scott B. \| Fischer, Eric S. \| Gray, Nathanael S. \| Huerta, Fidel \| Kong, Nikki R. \| ... \| Jones, Lyn H. RSC Chemical Biology, volume 3, issue 9, pages 1105-1110 (2022). 10.1039/D2CB00078D Cited by (24) \| Cite \| Source
On-Chip Preconcentration Microchip Capillary Electrophoresis Based CE-PRM-LIVE for High-Throughput Selectivity Profiling of Deubiquitinase Inhibitors (journal article) Zhu, He \| Mellors, J. Scott \| Chan, Wai Cheung \| Thompson, J. Will \| Ficarro, Scott B. \| Tavares, Isidoro \| Bratt, Ariana S. \| Decker, Jens \| Krause, Michael \| Kruppa, Gary \| ... \| Marto, Jarrod A. Analytical Chemistry, volume 94, issue 27, pages 9508-9513 (2022). 10.1021/acs.analchem.2c01337 Cited by (2) \| Cite \| Source
Open source fraction collector/MALDI spotter for proteomics (journal article) Ficarro, Scott B. \| Max Alexander, William \| Tavares, Isidoro \| Marto, Jarrod A. HardwareX, volume 11 (2022). 10.1016/j.ohx.2022.e00305 Cited by (6) \| Cite \| Source
Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase (journal article) Ji, Zhejian \| Li, Hao \| Peterle, Daniele \| Paulo, Joao A. \| Ficarro, Scott B. \| Wales, Thomas E. \| Marto, Jarrod A. \| Gygi, Steven P. \| Engen, John R. \| Rapoport, Tom A. Molecular Cell, volume 82, issue 3, pages 570-584.e8 (2022). 10.1016/j.molcel.2021.11.033 Cited by (37) \| Cite \| Source
PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors (journal article) Zhu, He \| Ficarro, Scott B. \| Alexander, William M. \| Fleming, Laura E. \| Adelmant, Guillaume \| Zhang, Tinghu \| Willetts, Matthew \| Decker, Jens \| Brehmer, Sven \| Krause, Michael \| ... \| Marto, Jarrod A. Analytical Chemistry, volume 93, issue 41, pages 13791-13799 (2021). 10.1021/acs.analchem.1c02349 Cited by (18) \| Cite \| Source
Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma (journal article) Jiang, Baishan \| Jiang, Jie \| Kaltheuner, Ines H. \| Iniguez, Amanda Balboni \| Anand, Kanchan \| Ferguson, Fleur M. \| Ficarro, Scott B. \| Seong, Bo Kyung Alex \| Greifenberg, Ann Katrin \| Dust, Sofia \| ... \| Gray, Nathanael S. European Journal of Medicinal Chemistry, volume 221 (2021). 10.1016/j.ejmech.2021.113481 Cited by (27) \| Cite \| Source
Exploring Ligand-Directed N -Acyl- N -alkylsulfonamide-Based Acylation Chemistry for Potential Targeted Degrader Development (journal article) Teng, Mingxing \| Jiang, Jie \| Ficarro, Scott B. \| Seo, Hyuk-Soo \| Bae, Jae Hyun \| Donovan, Katherine A. \| Fischer, Eric S. \| Zhang, Tinghu \| Dhe-Paganon, Sirano \| Marto, Jarrod A. \| Gray, Nathanael S. ACS Medicinal Chemistry Letters, volume 12, issue 8, pages 1302-1307 (2021). 10.1021/acsmedchemlett.1c00285 Cited by (5) \| Cite \| Source
BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage (journal article) Vohhodina, Jekaterina \| Goehring, Liana J. \| Liu, Ben \| Kong, Qing \| Botchkarev, Vladimir V. \| Huynh, Mai \| Liu, Zhiqi \| Abderazzaq, Fieda O. \| Clark, Allison P. \| Ficarro, Scott B. \| ... \| Livingston, David M. Nature Communications, volume 12, issue 1 (2021). 10.1038/s41467-021-23716-6 Cited by (52) \| Cite \| Source
A Non-Canonical Convergence of Carbohydrate and Glutamine Metabolism is Required After Metabolic Rewiring in a Solid Environment (journal article) Wei, Peng \| Bott, Alex J. \| Cluntun, Ahmad \| Morgan, Jeff \| Cunningham, Corey N. \| Schell, John C. \| Ouyang, Yeyun \| Ficarro, Scott B. \| Marto, Jarrod A. \| Danial, Nika N. \| ... \| Rutter, Jared SSRN Electronic Journal (2021). 10.2139/ssrn.3979182 Cite \| Source