Huilin Li | Scholar Profiles and Rankings

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The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader (journal article) Wang, Feng \| He, Qing \| Yao, Nina Y. \| O’Donnell, Michael E. \| Li, Huilin Nature Structural & Molecular Biology (2024). 10.1038/s41594-024-01332-4 Cite \| Source
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC (journal article) He, Qing \| Wang, Feng \| O’Donnell, Michael E. \| Li, Huilin Proceedings of the National Academy of Sciences, volume 121, issue 18 (2024). 10.1073/pnas.2319727121 Cite \| Source
Structural insight into an Arl1–ArfGEF complex involved in Golgi recruitment of a GRIP-domain golgin (journal article) Duan, H. Diessel \| Jain, Bhawik K. \| Li, Hua \| Graham, Todd R. \| Li, Huilin Nature Communications, volume 15, issue 1 (2024). 10.1038/s41467-024-46304-w Cite \| Source
Structure of the PCNA unloader Elg1-RFC (journal article) Zheng, Fengwei \| Yao, Nina Y. \| Georgescu, Roxana E. \| Li, Huilin \| O’Donnell, Michael E. Science Advances, volume 10, issue 9 (2024). 10.1126/sciadv.adl1739 Cited by (1) \| Cite \| Source
Structure of the M. tuberculosis DnaK−GrpE complex reveals how key DnaK roles are controlled (journal article) Xiao, Xiansha \| Fay, Allison \| Molina, Pablo Santos \| Kovach, Amanda \| Glickman, Michael S. \| Li, Huilin Nature Communications, volume 15, issue 1 (2024). 10.1038/s41467-024-44933-9 Cited by (4) \| Cite \| Source
Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors (journal article) Hsu, Hao-Chi \| Li, Daqiang \| Zhan, Wenhu \| Ye, Jianxiang \| Liu, Yi Jing \| Leung, Annie \| Qin, Junling \| Crespo, Benigno \| Gamo, Francisco-Javier \| Zhang, Hao \| ... \| Lin, Gang Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-44077-2 Cited by (1) \| Cite \| Source
Structural basis of the T4 bacteriophage primosome assembly and primer synthesis (journal article) Feng, Xiang \| Spiering, Michelle M. \| de Luna Almeida Santos, Ruda \| Benkovic, Stephen J. \| Li, Huilin Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-40106-2 Cited by (1) \| Cite \| Source
Molecular choreography of primer synthesis by the eukaryotic Pol α-primase (journal article) Yuan, Zuanning \| Georgescu, Roxana \| Li, Huilin \| O’Donnell, Michael E. Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-39441-1 Cited by (6) \| Cite \| Source
The structure of Arabidopsis phytochrome A reveals topological and functional diversification among the plant photoreceptor isoforms (journal article) Burgie, E. Sethe \| Li, Hua \| Gannam, Zira T. K. \| McLoughlin, Katrice E. \| Vierstra, Richard D. \| Li, Huilin Nature Plants, volume 9, issue 7, pages 1116-1129 (2023). 10.1038/s41477-023-01435-8 Cited by (4) \| Cite \| Source
Structural insights into the membrane chaperones for multi-pass membrane protein biogenesis (journal article) Bai, Lin \| Li, Huilin Current Opinion in Structural Biology, volume 79 (2023). 10.1016/j.sbi.2023.102563 Cited by (3) \| Cite \| Source
Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies (journal article) Guo, Zheng \| Kasinathan, Devi \| Merriman, Chengfeng \| Nakayama, Maki \| Li, Hua \| Li, Huilin \| Xu, Cheng \| Wong, G. William \| Yu, Liping \| Golson, Maria L. \| Fu, Dax Diabetes, volume 72, issue 2, pages 184-195 (2023). 10.2337/db22-0477 Cited by (3) \| Cite \| Source
SV40 T-antigen uses a DNA shearing mechanism to initiate origin unwinding (journal article) Langston, Lance D. \| Yuan, Zuanning \| Georgescu, Roxana \| Li, Huilin \| O’Donnell, Michael E. Proceedings of the National Academy of Sciences, volume 119, issue 49 (2022). 10.1073/pnas.2216240119 Cited by (4) \| Cite \| Source
Unexpected new insights into DNA clamp loaders (journal article) Li, Huilin \| O'Donnell, Mike \| Kelch, Brian BioEssays, volume 44, issue 11 (2022). 10.1002/bies.202200154 Cited by (6) \| Cite \| Source
The β-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation (journal article) Xiao, Xiansha \| Feng, Xiang \| Yoo, Jin Hee \| Kovach, Amanda \| Darwin, K. Heran \| Li, Huilin mSphere, volume 7, issue 5 (2022). 10.1128/msphere.00274-22 Cited by (1) \| Cite \| Source
Plant phytochrome B is an asymmetric dimer with unique signalling potential (journal article) Li, Hua \| Burgie, E. Sethe \| Gannam, Zira T. K. \| Li, Huilin \| Vierstra, Richard D. Nature, volume 604, issue 7904, pages 127-133 (2022). 10.1038/s41586-022-04529-z Cited by (34) \| Cite \| Source
Structure of the human GlcNAc-1-phosphotransferase αβ subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation (journal article) Li, Hua \| Lee, Wang-Sik \| Feng, Xiang \| Bai, Lin \| Jennings, Benjamin C. \| Liu, Lin \| Doray, Balraj \| Canfield, William M. \| Kornfeld, Stuart \| Li, Huilin Nature Structural & Molecular Biology, volume 29, issue 4, pages 348-356 (2022). 10.1038/s41594-022-00748-0 Cited by (9) \| Cite \| Source
DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp (journal article) Zheng, Fengwei \| Georgescu, Roxana E. \| Yao, Nina Y. \| O’Donnell, Michael E. \| Li, Huilin Nature Structural & Molecular Biology, volume 29, issue 4, pages 376-385 (2022). 10.1038/s41594-022-00742-6 Cited by (16) \| Cite \| Source
Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase (journal article) Feng, Xiang \| Schut, Gerrit J. \| Haja, Dominik K. \| Adams, Michael W. W. \| Li, Huilin Science Advances, volume 8, issue 8 (2022). 10.1126/sciadv.abm7546 Cited by (20) \| Cite \| Source
Pseudomonas aeruginosa C-Terminal Processing Protease CtpA Assembles into a Hexameric Structure That Requires Activation by a Spiral-Shaped Lipoprotein-Binding Partner (journal article) Hsu, Hao-Chi \| Wang, Michelle \| Kovach, Amanda \| Darwin, Andrew J. \| Li, Huilin mBio, volume 13, issue 1 (2022). 10.1128/mbio.03680-21 Cited by (8) \| Cite \| Source
Cryo‐EM structures of the endoplasmic reticulum membrane complex (journal article) Bai, Lin \| Li, Huilin The FEBS Journal, volume 289, issue 1, pages 102-112 (2022). 10.1111/febs.15786 Cited by (7) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Cryo-EM high performance data storage	LI, Huilin	2020	$100,000	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural mechanism of DNA replication	LI, Huilin	2020	$712,500	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
The structure and function of eukaryotic protein glycosylation enzymes	LI, Huilin	2020	$434,625	NATIONAL CANCER INSTITUTE
Structural biology of proteostasis in M. tuberculosis	LI, Huilin	2020	$475,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
The structure and function of eukaryotic protein glycosylation enzymes	LI, Huilin	2019	$421,585	NATIONAL CANCER INSTITUTE
Structural biology of proteostasis in M. tuberculosis	LI, Huilin	2019	$475,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Structural mechanism of DNA replication	LI, Huilin	2019	$681,429	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
The structure and function of eukaryotic protein glycosylation enzymes	LI, Huilin	2018	$434,625	NATIONAL CANCER INSTITUTE
Cryo-EM of the Eukaryotic Replisome	LI, Huilin	2018	$372,875	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural biology of proteostasis in M. tuberculosis	LI, Huilin	2018	$475,000	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Structural Basis of Eukaryotic Replication Initiation by Cryo-EM	LI, Huilin	2018	$375,250	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Cryo-EM of the Eukaryotic Replisome	LI, Huilin	2017	$372,875	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Eukaryotic Replication Initiation by Cryo-EM	LI, Huilin	2017	$375,250	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structure biology of Mycobacterium tuberculosis Pup-proteasome pathway	LI, Huilin	2016	$455,077	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Structural Basis of Eukaryotic Replication Initiation by Cryo-EM	LI, Huilin	2016	$375,250	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Eukaryotic Replication Initiation by Cryo-EM	LI, Huilin	2015	$312,050	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structure biology of Mycobacterium tuberculosis Pup-proteasome pathway	LI, Huilin	2015	$452,155	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Structure biology of Mycobacterium tuberculosis Pup-proteasome pathway	LI, Huilin	2014	$449,341	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Structure biology of Mycobacterium tuberculosis Pup-proteasome pathway	LI, Huilin	2013	$419,833	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Structure biology of Mycobacterium tuberculosis Pup-proteasome pathway	LI, Huilin	2012	$444,017	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
OUTER MEMBRANE PROTEIN PAPC USHER	LI, Huilin	2011	$4,600	NATIONAL CENTER FOR RESEARCH RESOURCES
OUTER MEMBRANE PROTEIN PAPC USHER	LI, Huilin	2010	$11,223	NATIONAL CENTER FOR RESEARCH RESOURCES
The Structural Basis of Eukaryotic Replication Origin Licensing by Cryo-EM	LI, Huilin	2010	$296,364	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
OUTER MEMBRANE PROTEIN PAPC USHER	LI, Huilin	2009	$5,224	NATIONAL CENTER FOR RESEARCH RESOURCES
The Structural Basis of Eukaryotic Replication Origin Licensing by Cryo-EM	LI, Huilin	2009	$256,405	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
The Structural Basis of Eukaryotic Replication Origin Licensing by Cryo-EM	LI, Huilin	2009	$297,930	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
CCD Camera for Cryo-EM	LI, Huilin	2009	$244,018	NATIONAL CENTER FOR RESEARCH RESOURCES
The Structural Basis of Eukaryotic Replication Origin Licensing by Cryo-EM	LI, Huilin	2008	$296,537	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
The Structural Basis of Eukaryotic Replication Origin Licensing by Cryo-EM	LI, Huilin	2007	$295,176	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
The Structural Basis of Eukaryotic Replication Origin Licensing by Cryo-EM	LI, Huilin	2006	$302,645	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES