Robert Klaus Hofstetter

ScholarGPS® ID: 88407432162202

Affiliation

University of Jena, Jena, Germany

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Biosynthesis | Cyclooxygenase

Metrics Summary

Publication Count

Predicted Citations

106

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole‐Based Inhibitors of Soluble Epoxide Hydrolase (sEH) (journal article) Gazzillo, Erica \| Colarusso, Ester \| Giordano, Assunta \| Chini, Maria Giovanna \| Potenza, Marianna \| Hofstetter, Robert Klaus \| Iorizzi, Maria \| Werz, Oliver \| Lauro, Gianluigi \| Bifulco, Giuseppe ChemPlusChem (2024). 10.1002/cplu.202400234 Cite \| Source
Exploring Microemulsion Systems for the Incorporation of Glucocorticoids into Bacterial Cellulose: A Novel Approach for Anti-Inflammatory Wound Dressings (journal article) Zahel, Paul \| Bruggink, Vera \| Hülsmann, Juliana \| Steiniger, Frank \| Hofstetter, Robert K. \| Heinzel, Thorsten \| Beekmann, Uwe \| Werz, Oliver \| Kralisch, Dana Pharmaceutics, volume 16, issue 4, pages 504- (2024). 10.3390/pharmaceutics16040504 Cite \| Source
Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution (journal article) Rao, Zhigang \| Brunner, Elena \| Giszas, Benjamin \| Iyer-Bierhoff, Aishwarya \| Gerstmeier, Jana \| Börner, Friedemann \| Jordan, Paul M. \| Pace, Simona \| Meyer, Katharina P. L. \| Hofstetter, Robert K. \| ... \| Werz, Oliver Proceedings of the National Academy of Sciences, volume 120, issue 35 (2023). 10.1073/pnas.2302070120 Cited by (2) \| Cite \| Source
Mycobacterium tuberculosis –Induced Prostaglandin J2 and 15-Deoxy-Prostaglandin J2 Inhibit Inflammatory Signals in Human M1 Macrophages via a Negative Feedback Loop (journal article) Ning, Yuping \| Wang, Wenfei \| Jordan, Paul M. \| Barth, Stefanie A. \| Hofstetter, Robert Klaus \| Xu, Jinjin \| Zhang, Ximeng \| Cai, Yi \| Menge, Christian \| Chen, Xinchun \| Werz, Oliver The Journal of Immunology, volume 210, issue 10, pages 1564-1575 (2023). 10.4049/jimmunol.2200820 Cited by (2) \| Cite \| Source
Phytochemical profile and anti-inflammatory activity of a commercially available Rhodiola rosea root extract (journal article) Masi, Francesca \| Chianese, Giuseppina \| Hofstetter, Robert K. \| Cavallaro, Arianna Lucia \| Riva, Antonella \| Werz, Oliver \| Taglialatela-Scafati, Orazio Fitoterapia, volume 166 (2023). 10.1016/j.fitote.2023.105439 Cited by (4) \| Cite \| Source
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors (journal article) Potenza, Marianna \| Giordano, Assunta \| Chini, Maria G. \| Saviano, Anella \| Kretzer, Christian \| Raucci, Federica \| Russo, Marina \| Lauro, Gianluigi \| Terracciano, Stefania \| Bruno, Ines \| ... \| Bifulco, Giuseppe ACS Medicinal Chemistry Letters, volume 14, issue 1, pages 26-34 (2023). 10.1021/acsmedchemlett.2c00343 Cite \| Source
Identification of 2,4‐Dinitro‐Biphenyl‐Based Compounds as MAPEG Inhibitors (journal article) Di Micco, Simone \| Terracciano, Stefania \| Pierri, Martina \| Cantone, Vincenza \| Liening, Stefanie \| König, Stefanie \| Garscha, Ulrike \| Hofstetter, Robert Klaus \| Koeberle, Andreas \| Werz, Oliver \| ... \| Bifulco, Giuseppe ChemMedChem, volume 17, issue 22 (2022). 10.1002/cmdc.202200327 Cited by (1) \| Cite \| Source
Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition (journal article) Colarusso, Ester \| Potenza, Marianna \| Lauro, Gianluigi \| Chini, Maria Giovanna \| Sepe, Valentina \| Zampella, Angela \| Fischer, Katrin \| Hofstetter, Robert K. \| Werz, Oliver \| Bifulco, Giuseppe European Journal of Medicinal Chemistry Reports, volume 5 (2022). 10.1016/j.ejmcr.2022.100046 Cited by (5) \| Cite \| Source
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation (journal article) Gazzillo, Erica \| Terracciano, Stefania \| Ruggiero, Dafne \| Potenza, Marianna \| Chini, Maria Giovanna \| Lauro, Gianluigi \| Fischer, Katrin \| Hofstetter, Robert Klaus \| Giordano, Assunta \| Werz, Oliver \| ... \| Bifulco, Giuseppe Molecules, volume 27, issue 12, pages 3866- (2022). 10.3390/molecules27123866 Cited by (5) \| Cite \| Source
Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages (journal article) Kretzer, Christian \| Jordan, Paul M. \| Meyer, Katharina P.L. \| Hoff, Daniel \| Werner, Markus \| Hofstetter, Robert Klaus \| Koeberle, Andreas \| Cala Peralta, Antonio \| Viault, Guillaume \| Seraphin, Denis \| ... \| Werz, Oliver Biochemical Pharmacology, volume 195 (2022). 10.1016/j.bcp.2021.114825 Cited by (15) \| Cite \| Source
In Silico, In Vitro, and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from Salvia miltiorrhiza as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway (journal article) Saviano, Anella \| De Vita, Simona \| Chini, Maria Giovanna \| Marigliano, Noemi \| Lauro, Gianluigi \| Casillo, Gian Marco \| Raucci, Federica \| Iorizzi, Maria \| Hofstetter, Robert Klaus \| Fischer, Katrin \| ... \| Bifulco, Giuseppe Biomolecules, volume 12, issue 1, pages 99- (2022). 10.3390/biom12010099 Cited by (2) \| Cite \| Source
Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization (journal article) Zhang, Kehong \| Jordan, Paul Mike \| Pace, Simona \| Hofstetter, Robert K \| Werner, Markus \| Chen, Xinchun \| Werz, Oliver Journal of Inflammation Research, volume Volume 15 (2022). 10.2147/JIR.S356964 Cited by (3) \| Cite \| Source
Structure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathways (journal article) Potenza, Marianna \| Sciarretta, Martina \| Chini, Maria Giovanna \| Saviano, Anella \| Maione, Francesco \| D'Auria, Maria Valeria \| De Marino, Simona \| Giordano, Assunta \| Hofstetter, Robert Klaus \| Festa, Carmen \| ... \| Bifulco, Giuseppe European Journal of Medicinal Chemistry, volume 224 (2021). 10.1016/j.ejmech.2021.113693 Cited by (13) \| Cite \| Source
Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase‐1 Inhibitors by Automated De Novo Design (journal article) Friedrich, Lukas \| Cingolani, Gino \| Ko, Ying‐Hui \| Iaselli, Mariaclara \| Miciaccia, Morena \| Perrone, Maria Grazia \| Neukirch, Konstantin \| Bobinger, Veronika \| Merk, Daniel \| Hofstetter, Robert Klaus \| ... \| Schneider, Gisbert Advanced Science, volume 8, issue 16 (2021). 10.1002/advs.202100832 Cited by (16) \| Cite \| Source
Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators (journal article) Pace, Simona \| Zhang, Kehong \| Jordan, Paul M. \| Bilancia, Rossella \| Wang, Wenfei \| Börner, Friedemann \| Hofstetter, Robert K. \| Potenza, Marianna \| Kretzer, Christian \| Gerstmeier, Jana \| ... \| Werz, Oliver Pharmacological Research, volume 167 (2021). 10.1016/j.phrs.2021.105556 Cited by (21) \| Cite \| Source
Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides (journal article) Zhang, Kehong \| Pace, Simona \| Jordan, Paul M. \| Peltner, Lukas K. \| Weber, Alexander \| Fischer, Dagmar \| Hofstetter, Robert K. \| Chen, Xinchun \| Werz, Oliver Biomolecules, volume 11, issue 5, pages 746- (2021). 10.3390/biom11050746 Cited by (11) \| Cite \| Source