Kapil Bharti

ScholarGPS® ID: 88363546319305

Affiliation

National Eye Institute, National Institutes of Health, Bethesda, United States

Affiliation History

Field

Life Sciences

Discipline

Genetics

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

6,297

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Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Considerations for Developing an Autologous Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) Replacement Therapy (journal article) Bose, Devika \| Ortolan, Davide \| Farnoodian, Mitra \| Sharma, Ruchi \| Bharti, Kapil Cold Spring Harbor Perspectives in Medicine, volume 14, issue 3, pages a041295- (2024). 10.1101/cshperspect.a041295 Cite \| Source
An Automated Visual Psychophysics Method to Measure Visual Function in Swine Preclinical Animal Model (journal article) Barone, Francesca \| Bunea, Irina \| Creel, Kristi \| Sharma, Ruchi \| Amaral, Juan \| Maminishkis, Arvydas \| Bharti, Kapil Translational Vision Science & Technology, volume 13, issue 3, pages 8- (2024). 10.1167/tvst.13.3.8 Cite \| Source
Differentiation of monocytes and polarized M1/M2 macrophages from human induced pluripotent stem cells (journal article) Park, Tea Soon \| Hirday, Rishabh \| Quinn, Russell \| Jacob, Sheela Panicker \| Feldman, Ricardo A. \| Bose, Devika \| Sharma, Ruchi \| Bharti, Kapil STAR Protocols, volume 5, issue 1, pages 102827- (2024). 10.1016/j.xpro.2023.102827 Cited by (1) \| Cite \| Source
Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration (journal article) Kretschmer, Viola \| Schneider, Sandra \| Matthiessen, Peter Andreas \| Reichert, Dominik \| Hotaling, Nathan \| Glasßer, Gunnar \| Lieberwirth, Ingo \| Bharti, Kapil \| De Cegli, Rossella \| Conte, Ivan \| ... \| May-Simera, Helen Louise PLOS Biology, volume 21, issue 12, pages e3002402- (2023). 10.1371/journal.pbio.3002402 Cited by (1) \| Cite \| Source
Invited Session II: Retinal remodeling and regeneration: Developing autologous iPSC-RPE therapy for the treatment of AMD patients (journal article) Sharma, Ruchi \| Bharti, Kapil Journal of Vision, volume 23, issue 15, pages 9- (2023). 10.1167/jov.23.15.9 Cite \| Source
A biologically validated mathematical model for decoding epithelial apical, basolateral, and paracellular electrical properties (journal article) Lewallen, Colby F. \| Chien, Athena \| Maminishkis, Arvydas \| Hirday, Rishabh \| Reichert, Dominik \| Sharma, Ruchi \| Wan, Qin \| Bharti, Kapil \| Forest, Craig R. American Journal of Physiology-Cell Physiology, volume 325, issue 6, pages C1470-C1484 (2023). 10.1152/ajpcell.00200.2023 Cite \| Source
Retina and RPE lipid profile changes linked with ABCA4 associated Stargardt's maculopathy (journal article) Farnoodian, Mitra \| Bose, Devika \| Barone, Francesca \| Nelson, Luke Mathew \| Boyle, Marisa \| Jun, Bokkyoo \| Do, Khanh \| Gordon, William \| Guerin, Marie-Audrey Kautzmann \| Perera, Rasangi \| ... \| Bharti, Kapil Pharmacology & Therapeutics, volume 249 (2023). 10.1016/j.pharmthera.2023.108482 Cited by (5) \| Cite \| Source
Progress in Stem Cells-Based Replacement Therapy for Retinal Pigment Epithelium: In Vitro Differentiation to In Vivo Delivery (journal article) Gupta, Santosh \| Lytvynchuk, Lyubomyr \| Ardan, Taras \| Studenovska, Hana \| Sharma, Ruchi \| Faura, Georgina \| Eide, Lars \| Shanker Verma, Rama \| Znaor, Ljubo \| Erceg, Slaven \| ... \| Bharti, Kapil Stem Cells Translational Medicine, volume 12, issue 8, pages 536-552 (2023). 10.1093/stcltm/szad039 Cited by (3) \| Cite \| Source
A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing (journal article) Barone, Francesca \| Amaral, Juan \| Bunea, Irina \| Farnoodian, Mitra \| Gupta, Rohan \| Gupta, Rishabh \| Baker, Dara \| Phillips, M. Joseph \| Blanch, Richard J. \| Maminishkis, Arvydas \| ... \| Bharti, Kapil JCI Insight, volume 8, issue 11 (2023). 10.1172/jci.insight.157654 Cited by (1) \| Cite \| Source
Protocol to generate endothelial cells, pericytes, and fibroblasts in one differentiation round from human-induced pluripotent stem cells (journal article) Park, Tea Soon \| Hirday, Rishabh \| Ali, Amir \| Megersa, Roba \| Villasmil, Rafael \| Nguyen, Eric \| Bharti, Kapil STAR Protocols, volume 4, issue 2, pages 102292- (2023). 10.1016/j.xpro.2023.102292 Cited by (4) \| Cite \| Source
Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report (journal article) Fortress, Ashley M. \| Miyagishima, Kiyoharu J. \| Reed, Amberlynn A. \| Temple, Sally \| Clegg, Dennis O. \| Tucker, Budd A. \| Blenkinsop, Timothy A. \| Harb, George \| Greenwell, Thomas N. \| Ludwig, Tenneille E. \| Bharti, Kapil Stem Cell Research & Therapy, volume 14, issue 1 (2023). 10.1186/s13287-023-03282-y Cited by (5) \| Cite \| Source
Retinal Pigment Epithelium Cell Development: Extrapolating Basic Biology to Stem Cell Research (journal article) Gupta, Santosh \| Lytvynchuk, Lyubomyr \| Ardan, Taras \| Studenovska, Hana \| Faura, Georgina \| Eide, Lars \| Znaor, Ljubo \| Erceg, Slaven \| Stieger, Knut \| Motlik, Jan \| ... \| Petrovski, Goran Biomedicines, volume 11, issue 2, pages 310- (2023). 10.3390/biomedicines11020310 Cited by (5) \| Cite \| Source
LipidUNet-Machine Learning-Based Method of Characterization and Quantification of Lipid Deposits Using iPSC-Derived Retinal Pigment Epithelium (journal article) Esh, Zander \| Suresh, Sharanya \| Ortolan, Davide \| Farnoodian, Mitra \| Bose, Devika \| Ryu, Jiwon \| Volkov, Andrei \| Bharti, Kapil \| Sharma, Ruchi Journal of Visualized Experiments (2023). 10.3791/65503 Cited by (2) \| Cite \| Source
Developing autologous cell therapy for macular degeneration: From bench‐to‐bedside (journal article) Bharti, Kapil \| Investigator, Senior Acta Ophthalmologica, volume 100, issue S275 (2022). 10.1111/j.1755-3768.2022.15520 Cited by (1) \| Cite \| Source
Cell-autonomous lipid-handling defects in Stargardt iPSC-derived retinal pigment epithelium cells (journal article) Farnoodian, Mitra \| Bose, Devika \| Khristov, Vladimir \| Susaimanickam, Praveen Joseph \| Maddileti, Savitri \| Mariappan, Indumathi \| Abu-Asab, Mones \| Campos, Maria \| Villasmil, Rafael \| Wan, Qin \| ... \| Bharti, Kapil Stem Cell Reports, volume 17, issue 11, pages 2438-2450 (2022). 10.1016/j.stemcr.2022.10.001 Cited by (11) \| Cite \| Source
Perspectives on the cost of goods for hPSC banks for manufacture of cell therapies (journal article) Kim, Jung-Hyun \| Kawase, Eihachiro \| Bharti, Kapil \| Karnieli, Ohad \| Arakawa, Yuji \| Stacey, Glyn npj Regenerative Medicine, volume 7, issue 1 (2022). 10.1038/s41536-022-00242-7 Cited by (11) \| Cite \| Source
Cell culture models to study retinal pigment epithelium-related pathogenesis in age-related macular degeneration (journal article) Bharti, Kapil \| den Hollander, Anneke I. \| Lakkaraju, Aparna \| Sinha, Debasish \| Williams, David S. \| Finnemann, Silvia C. \| Bowes-Rickman, Catherine \| Malek, Goldis \| D'Amore, Patricia A. Experimental Eye Research, volume 222 (2022). 10.1016/j.exer.2022.109170 Cited by (31) \| Cite \| Source
Triphasic developmentally guided protocol to generate retinal pigment epithelium from induced pluripotent stem cells (journal article) Sharma, Ruchi \| Bose, Devika \| Montford, Jair \| Ortolan, Davide \| Bharti, Kapil STAR Protocols, volume 3, issue 3, pages 101582- (2022). 10.1016/j.xpro.2022.101582 Cited by (8) \| Cite \| Source
Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs (journal article) Ripolles-Garcia, Ana \| Dolgova, Natalia \| Phillips, M. Joseph \| Savina, Svetlana \| Ludwig, Allison L. \| Stuedemann, Sara A. \| Nlebedum, Uchenna \| Wolfe, John H. \| Garden, Oliver A. \| Maminishkis, Arvydas \| ... \| Beltran, William A. Stem Cell Reports, volume 17, issue 8, pages 1824-1841 (2022). 10.1016/j.stemcr.2022.06.009 Cited by (15) \| Cite \| Source
Single-cell–resolution map of human retinal pigment epithelium helps discover subpopulations with differential disease sensitivity (journal article) Ortolan, Davide \| Sharma, Ruchi \| Volkov, Andrei \| Maminishkis, Arvydas \| Hotaling, Nathan A. \| Huryn, Laryssa A. \| Cukras, Catherine \| Di Marco, Stefano \| Bisti, Silvia \| Bharti, Kapil Proceedings of the National Academy of Sciences, volume 119, issue 19 (2022). 10.1073/pnas.2117553119 Cited by (35) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Developing 3D patient-specific iPS cell derived RPE/choroid models	Bharti, Kapil	2019	$1,291,642	NATIONAL EYE INSTITUTE
Developing autologous iPSC-RPE based IND for AMD patients	Bharti, Kapil	2019	$1,450,454	NATIONAL EYE INSTITUTE
Developing functional and authenticated RPE tissue from iPS cells	Bharti, Kapil	2019	$729,819	NATIONAL EYE INSTITUTE
Developing an 'aging' model using iPSC-derived RPE cells	Bharti, Kapil	2019	$1,836,940	NATIONAL EYE INSTITUTE
Developing 3D patient-specific iPS cell derived RPE/choroid models	Bharti, Kapil	2018	$1,156,355	NATIONAL EYE INSTITUTE
Developing autologous iPSC-RPE based IND for AMD patients	Bharti, Kapil	2018	$1,644,542	NATIONAL EYE INSTITUTE
Developing functional and authenticated RPE tissue from iPS cells	Bharti, Kapil	2018	$761,834	NATIONAL EYE INSTITUTE
Developing an 'aging' model using iPSC-derived RPE cells	Bharti, Kapil	2018	$1,659,709	NATIONAL EYE INSTITUTE
Developing 3D patient-specific iPS cell derived RPE/choroid models	Bharti, Kapil	2017	$1,598,816	NATIONAL EYE INSTITUTE
Developing autologous iPSC-RPE based IND for AMD patients	Bharti, Kapil	2017	$2,219,219	NATIONAL EYE INSTITUTE
Developing functional and authenticated RPE tissue from iPS cells	Bharti, Kapil	2017	$183,772	NATIONAL EYE INSTITUTE
Developing an 'aging' model using iPSC-derived RPE cells	Bharti, Kapil	2017	$1,155,138	NATIONAL EYE INSTITUTE
Developing functional and authenticated RPE tissue from iPS cells	Bharti, Kapil	2016	$367,352	NATIONAL EYE INSTITUTE
Developing autologous iPSC-RPE based IND for AMD patients	Bharti, Kapil	2016	$2,850,386	NATIONAL EYE INSTITUTE
Developing patient-specific iPS cell derived RPE disease models	Bharti, Kapil	2016	$1,574,364	NATIONAL EYE INSTITUTE
Molecular and physiological authentication of iPS cell derived RPE	Bharti, Kapil	2016	$78,718	NATIONAL EYE INSTITUTE
Developing autologous iPSC-RPE based IND for AMD patients	Bharti, Kapil	2015	$712,226	NATIONAL EYE INSTITUTE
Developing functional and authenticated RPE tissue from iPS cells	Bharti, Kapil	2015	$719,277	NATIONAL EYE INSTITUTE
Developing patient-specific iPS cell derived RPE disease models	Bharti, Kapil	2015	$1,191,744	NATIONAL EYE INSTITUTE
Molecular and physiological authentication of iPS cell derived RPE	Bharti, Kapil	2015	$91,673	NATIONAL EYE INSTITUTE
Developing autologous iPSC-RPE based IND for AMD patients	Bharti, Kapil	2014	$1,448,812	NATIONAL EYE INSTITUTE
Developing functional and authenticated RPE tissue from iPS cells	Bharti, Kapil	2014	$623,106	NATIONAL EYE INSTITUTE
Developing patient-specific iPS cell derived RPE disease models	Bharti, Kapil	2014	$1,066,796	NATIONAL EYE INSTITUTE
Molecular and physiological authentication of iPS cell derived RPE	Bharti, Kapil	2014	$121,227	NATIONAL EYE INSTITUTE
Molecular and physiological authentication of iPS cell derived RPE	Bharti, Kapil	2013	$153,655	NATIONAL EYE INSTITUTE
Developing functional and authenticated RPE tissue from iPS cells	Bharti, Kapil	2013	$494,749	NATIONAL EYE INSTITUTE
Developing patient-specific iPS cell derived RPE disease models	Bharti, Kapil	2013	$458,600	NATIONAL EYE INSTITUTE