Kebing Yu

ScholarGPS® ID: 86986779454164

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Proteomics | Cell Death

Metrics Summary

Publication Count

Predicted Citations

826

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2 (journal article) Goncharov, Tatiana \| Kőműves, László G. \| Kist, Matthias \| Castellanos, Erick R. \| Witt, Axel \| Fedorova, Anna V. \| Izrael-Tomasevic, Anita \| Yu, Kebing \| Keir, Mary \| Matsumoto, Marissa L. \| Vucic, Domagoj Science Signaling, volume 17, issue 819 (2024). 10.1126/scisignal.abn1101 Cite \| Source
AzidoTMT Enables Direct Enrichment and Highly Multiplexed Quantitation of Proteome-Wide Functional Residues (journal article) Ma, Taylur P. \| Izrael-Tomasevic, Anita \| Mroue, Rana \| Budayeva, Hanna \| Malhotra, Sushant \| Raisner, Ryan \| Evangelista, Marie \| Rose, Christopher M. \| Kirkpatrick, Donald S. \| Yu, Kebing Journal of Proteome Research, volume 22, issue 7, pages 2218-2231 (2023). 10.1021/acs.jproteome.2c00703 Cited by (2) \| Cite \| Source
Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action (journal article) Chan, Jocelyn \| Chan, Joyce \| Shao, Lily \| Stawicki, Scott S. \| Pham, Victoria C. \| Akita, Rob W. \| Hafner, Marc \| Crocker, Lisa \| Yu, Kebing \| Koerber, James T. \| ... \| Comps-Agrar, Laetitia Journal of Biological Chemistry, volume 299, issue 1, pages 102729- (2023). 10.1016/j.jbc.2022.102729 Cite \| Source
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein (journal article) den Besten, Willem \| Verma, Kshitij \| Yamazoe, Sayumi \| Blaquiere, Nicole \| Phung, Wilson \| Izrael-Tomasevic, Anita \| Mulvihill, Melinda M. \| Helgason, Elizabeth \| Prakash, Sumit \| Goncharov, Tatiana \| ... \| Staben, Steven T. Journal of the American Chemical Society, volume 143, issue 28, pages 10571-10575 (2021). 10.1021/jacs.1c05269 Cited by (9) \| Cite \| Source
Chaperone mediated detection of small molecule target binding in cells (journal article) Cho, Kelvin F. \| Ma, Taylur P. \| Rose, Christopher M. \| Kirkpatrick, Donald S. \| Yu, Kebing \| Blake, Robert A. Nature Communications, volume 11, issue 1 (2020). 10.1038/s41467-019-14033-0 Cited by (8) \| Cite \| Source
The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function (journal article) Oberbeck, Nina \| Pham, Victoria C. \| Webster, Joshua D. \| Reja, Rohit \| Huang, Christine S. \| Zhang, Yue \| Roose-Girma, Merone \| Warming, Søren \| Li, Qingling \| Birnberg, Andrew \| ... \| Dixit, Vishva M. Nature, volume 574, issue 7777, pages 249-253 (2019). 10.1038/s41586-019-1615-3 Cited by (45) \| Cite \| Source
Discovery and Qualification of Candidate Urinary Biomarkers of Disease Activity in Lupus Nephritis (journal article) Anania, Veronica G. \| Yu, Kebing \| Pingitore, Francesco \| Li, Qingling \| Rose, Christopher M. \| Liu, Peter \| Sandoval, Wendy \| Herman, Ann E. \| Lill, Jennie R. \| Mathews, W. Rodney Journal of Proteome Research, volume 18, issue 3, pages 1264-1277 (2019). 10.1021/acs.jproteome.8b00874 Cited by (18) \| Cite \| Source
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes (journal article) Hewings, David S. \| Heideker, Johanna \| Ma, Taylur P. \| AhYoung, Andrew P. \| El Oualid, Farid \| Amore, Alessia \| Costakes, Gregory T. \| Kirchhofer, Daniel \| Brasher, Bradley \| Pillow, Thomas \| ... \| Wertz, Ingrid E. Nature Communications, volume 9, issue 1 (2018). 10.1038/s41467-018-03511-6 Cited by (69) \| Cite \| Source \| Open Access
Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling (journal article) Goncharov, Tatiana \| Hedayati, Stefanie \| Mulvihill, Melinda M. \| Izrael-Tomasevic, Anita \| Zobel, Kerry \| Jeet, Surinder \| Fedorova, Anna V. \| Eidenschenk, Celine \| deVoss, Jason \| Yu, Kebing \| ... \| Vucic, Domagoj Molecular Cell, volume 69, issue 4, pages 551-565.e7 (2018). 10.1016/j.molcel.2018.01.016 Cited by (90) \| Cite \| Source
USP7 inhibitor compounds and methods of use (patent) Blake, Robert \| Di Lello, Paola \| Drummond, Jason \| Heideker, Christine Johanna \| Kategaya, Lorna \| Maurer, Till \| Murray, Jeremy M. \| Ndubaku, Chudi \| Pastor, Richard \| Rouge, Lionel \| ... \| Yu, Kebing Patent Number: 9573899 (2017) Cited by (1) \| Cite \| Source
Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death (journal article) de Almagro, M Cristina \| Goncharov, Tatiana \| Izrael-Tomasevic, Anita \| Duttler, Stefanie \| Kist, Matthias \| Varfolomeev, Eugene \| Wu, Xiumin \| Lee, Wyne P \| Murray, Jeremy \| Webster, Joshua D \| ... \| Vucic, Domagoj Cell Death & Differentiation, volume 24, issue 1, pages 26-37 (2017). 10.1038/cdd.2016.78 Cited by (91) \| Cite \| Source \| Open Access
Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death (journal article) Anania, Veronica G. \| Yu, Kebing \| Gnad, Florian \| Pferdehirt, Rebecca R. \| Li, Han \| Ma, Taylur P. \| Jeon, Diana \| Fortelny, Nikolaus \| Forrest, William \| Ashkenazi, Avi \| ... \| Lill, Jennie R. Molecular & Cellular Proteomics, volume 15, issue 7, pages 2293-2307 (2016). 10.1074/mcp.M115.055376 Cited by (7) \| Cite \| Source \| Open Access
Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis (journal article) Vartanian, Steffan \| Ma, Taylur P. \| Lee, James \| Haverty, Peter M. \| Kirkpatrick, Donald S. \| Yu, Kebing \| Stokoe, David Molecular & Cellular Proteomics, volume 15, issue 4, pages 1220-1231 (2016). 10.1074/mcp.M115.055509 Cited by (84) \| Cite \| Source \| Open Access
Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress (journal article) D’Osualdo, Andrea \| Anania, Veronica G. \| Yu, Kebing \| Lill, Jennie R. \| Kaufman, Randal J. \| Matsuzawa, Shu-ichi \| Reed, John C. PLOS ONE, volume 10, issue 6, pages e0130635- (2015). 10.1371/journal.pone.0130635 Cited by (44) \| Cite \| Source \| Open Access
Immunoaffinity Enrichment Coupled to Quantitative Mass Spectrometry Reveals Ubiquitin-Mediated Signaling Events (journal article) Yu, Kebing \| Phu, Lilian \| Varfolomeev, Eugene \| Bustos, Daisy \| Vucic, Domagoj \| Kirkpatrick, Donald S. Journal of Molecular Biology, volume 427, issue 11, pages 2121-2134 (2015). 10.1016/j.jmb.2015.03.018 Cited by (13) \| Cite \| Source
Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment (journal article) Varfolomeev, Eugene \| Izrael-Tomasevic, Anita \| Yu, Kebing \| Bustos, Daisy \| Goncharov, Tatiana \| Belmont, Lisa D. \| Masselot, Alexandre \| Bakalarski, Corey E. \| Kirkpatrick, Donald S. \| Vucic, Domagoj Biochemical Journal, volume 466, issue 1, pages 45-54 (2015). 10.1042/BJ20141195 Cited by (9) \| Cite \| Source
A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation (journal article) Bentley, Carolyn \| Jurinka, Stefanie S. \| Kljavin, Noelyn M. \| Vartanian, Steffan \| Ramani, Sree R. \| Gonzalez, Lino C. \| Yu, Kebing \| Modrusan, Zora \| Du, Pan \| Bourgon, Richard \| ... \| Stokoe, David Biochemical Journal, volume 452, issue 2, pages 313-320 (2013). 10.1042/BJ20121578 Cited by (35) \| Cite \| Source \| Open Access
Phosphoproteomic Analysis Implicates the mTORC2-FoxO1 Axis in VEGF Signaling and Feedback Activation of Receptor Tyrosine Kinases (journal article) Zhuang, Guanglei \| Yu, Kebing \| Jiang, Zhaoshi \| Chung, Alicia \| Yao, Jenny \| Ha, Connie \| Toy, Karen \| Soriano, Robert \| Haley, Benjamin \| Blackwood, Elizabeth \| ... \| Ferrara, Napoleone Science Signaling, volume 6, issue 271 (2013). 10.1126/scisignal.2003572 Cited by (62) \| Cite \| Source
Complementary Proteomic Tools for the Dissection of Apoptotic Proteolysis Events (journal article) Pham, Victoria C. \| Pitti, Robert \| Anania, Veronica G. \| Bakalarski, Corey E. \| Bustos, Daisy \| Jhunjhunwala, Suchit \| Phung, Qui T. \| Yu, Kebing \| Forrest, William F. \| Kirkpatrick, Donald S. \| ... \| Lill, Jennie R. Journal of Proteome Research, volume 11, issue 5, pages 2947-2954 (2012). 10.1021/pr300035k Cited by (21) \| Cite \| Source