Susmith Mukund

ScholarGPS® ID: 86790007362142

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

HIV | Peptide

Metrics Summary

Publication Count

Predicted Citations

1,632

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells (journal article) Nile, Aaron H. \| de Sousa e Melo, Felipe \| Mukund, Susmith \| Piskol, Robert \| Hansen, Simon \| Zhou, Lijuan \| Zhang, Yingnan \| Fu, Yue \| Gogol, Emily B. \| Kömüves, László G. \| ... \| Hannoush, Rami N. Nature Chemical Biology, volume 14, issue 6, pages 582-590 (2018). 10.1038/s41589-018-0035-2 Cited by (52) \| Cite \| Source
A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells (journal article) Nile, Aaron H. \| Melo, F. de Sousa e \| Mukund, Susmith \| Piskol, Robert \| Hansen, Simon \| Zhou, Lijuan \| Zhang, Yingnan \| Fu, Y. \| Gogol, Emily \| Komuves, Laszlo \| ... \| Hannoush, Rami N. Nature Chemical Biology, volume 14, issue 6, pages 582-590 (2018). 10.2210/pdb5wbs/pdb Cited by (3) \| Cite \| Source
Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding (journal article) Nile, Aaron H. \| Mukund, Susmith \| Stanger, Karen \| Wang, Weiru \| Hannoush, Rami N. Proceedings of the National Academy of Sciences, volume 114, issue 16, pages 4147-4152 (2017). 10.1073/pnas.1618293114 Cited by (90) \| Cite \| Source \| Open Access
Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions (journal article) Chiang, Eugene Y. \| Li, Tianbo \| Jeet, Surinder \| Peng, Ivan \| Zhang, Juan \| Lee, Wyne P. \| DeVoss, Jason \| Caplazi, Patrick \| Chen, Jun \| Warming, Søren \| ... \| Grogan, Jane L. Nature Communications, volume 8, issue 1 (2017). 10.1038/ncomms14644 Cited by (72) \| Cite \| Source \| Open Access
Structural Basis of Nav1.7 Inhibition by an Isoform-Selective Small Molecule Antagonist (journal article) Hackos, David H. \| Ahuja, Shivani \| Mukund, Susmith \| Deng, Lunbin \| Khakh, Kuldip \| Chang, Elaine \| Young, Clint \| Lin, Sophia \| Johnson, J.P. \| Ortwine, Daniel F. \| ... \| Payandeh, Jian Biophysical Journal, volume 110, issue 3, pages 33a-34a (2016). 10.1016/j.bpj.2015.11.249 Cite \| Source \| Open Access
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor (journal article) Mukund, Susmith \| Shang, Yonglei \| Clarke, Holly J. \| Madjidi, Azadeh \| Corn, Jacob E. \| Kates, Lance \| Kolumam, Ganesh \| Chiang, Vicky \| Luis, Elizabeth \| Murray, Jeremy \| ... \| Allan, Bernard B. Journal of Biological Chemistry, volume 288, issue 50, pages 36168-36178 (2013). 10.1074/jbc.M113.496984 Cited by (32) \| Cite \| Source \| Open Access
Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability (journal article) Lauffer, Benjamin E.L. \| Mintzer, Robert \| Fong, Rina \| Mukund, Susmith \| Tam, Christine \| Zilberleyb, Inna \| Flicke, Birgit \| Ritscher, Allegra \| Fedorowicz, Grazyna \| Vallero, Roxanne \| ... \| Steiner, Pascal Journal of Biological Chemistry, volume 288, issue 37, pages 26926-26943 (2013). 10.1074/jbc.M113.490706 Cited by (315) \| Cite \| Source \| Open Access
Molecular basis for negative regulation of the glucagon receptor (journal article) Koth, Christopher M. \| Murray, Jeremy M. \| Mukund, Susmith \| Madjidi, Azadeh \| Minn, Alexandra \| Clarke, Holly J. \| Wong, Terence \| Chiang, Vicki \| Luis, Elizabeth \| Estevez, Alberto \| ... \| Allan, Bernard B. Proceedings of the National Academy of Sciences, volume 109, issue 36, pages 14393-14398 (2012). 10.1073/pnas.1206734109 Cited by (112) \| Cite \| Source \| Open Access
Dithiothreitol Causes HIV-1 Integrase Dimer Dissociation While Agents Interacting With the Integrase Dimer Interface Promote Dimer Formation (journal article) Tsiang, Manuel \| Jones, Gregg S. \| Hung, Magdeleine \| Samuel, Dharmaraj \| Novikov, Nikolai \| Mukund, Susmith \| Brendza, Katherine M. \| Niedziela-Majka, Anita \| Jin, Debi \| Liu, Xiaohong \| ... \| Geleziunas, Romas Biochemistry, volume 50, issue 10, pages 1567-1581 (2011). 10.1021/bi101504w Cited by (18) \| Cite \| Source
Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design (journal article) Lansdon, Eric B. \| Brendza, Katherine M. \| Hung, Magdeleine \| Wang, Ruth \| Mukund, Susmith \| Jin, Debi \| Birkus, Gabriel \| Kutty, Nilima \| Liu, Xiaohong Journal of Medicinal Chemistry, volume 53, issue 10, pages 4295-4299 (2010). 10.1021/jm1002233 Cited by (191) \| Cite \| Source
R‐ to T‐ Transition in Fructose‐1,6‐bisphosphatase: Loop Displacement is the Penultimate Step to Inactivation (journal article) Gao, Yang \| Iancu, Cristina V \| Mukund, Susmith \| Honzatko, Richard B The FASEB Journal, volume 24, issue S1 (2010). 10.1096/fasebj.24.1_supplement.468.2 Cite \| Source
Affinities between the Binding Partners of the HIV-1 Integrase Dimer-Lens Epithelium-derived Growth Factor (IN Dimer-LEDGF) Complex (journal article) Tsiang, Manuel \| Jones, Gregg S. \| Hung, Magdeleine \| Mukund, Susmith \| Han, Bin \| Liu, Xiaohong \| Babaoglu, Kerim \| Lansdon, Eric \| Chen, Xiaowu \| Todd, Jacob \| ... \| Geleziunas, Romas Journal of Biological Chemistry, volume 284, issue 48, pages 33580-33599 (2009). 10.1074/jbc.M109.040121 Cited by (41) \| Cite \| Source \| Open Access
R-State AMP Complex Reveals Initial Steps of the Quaternary Transition of Fructose-1,6-bisphosphatase (journal article) Iancu, Cristina V. \| Mukund, Susmith \| Fromm, Herbert J. \| Honzatko, Richard B. Journal of Biological Chemistry, volume 280, issue 20, pages 19737-19745 (2005). 10.1074/jbc.M501011200 Cited by (22) \| Cite \| Source \| Open Access
Amino terminus of Plasmodium falciparum acidic basic repeat antigen interacts with the erythrocyte membrane through band 3 protein (journal article) Kushwaha, Ashima \| Perween, Ashiya \| Mukund, Susmith \| Majumdar, Suman \| Bhardwaj, Devesh \| Chowdhury, Nirupam Roy \| Chauhan, Virander S Molecular and Biochemical Parasitology, volume 122, issue 1, pages 45-54 (2002). 10.1016/S0166-6851(02)00077-4 Cited by (26) \| Cite \| Source
Characterization of a novel tungsten-containing formaldehyde ferredoxin oxidoreductase from the hyperthermophilic archaeon, Thermococcus litoralis. A role for tungsten in peptide catabolism (journal article) Mukund, S. \| Adams, M.W. Journal of Biological Chemistry, volume 268, issue 18, pages 13592-13600 (1993). 10.1016/S0021-9258(19)38690-9 Cited by (98) \| Cite \| Source
Identification of molybdopterin as the organic component of the tungsten cofactor in four enzymes from hyperthermophilic Archaea. (journal article) Johnson, J.L. \| Rajagopalan, K.V. \| Mukund, S. \| Adams, M.W. Journal of Biological Chemistry, volume 268, issue 7, pages 4848-4852 (1993). 10.1016/S0021-9258(18)53474-8 Cited by (63) \| Cite \| Source