Manuela Porru

ScholarGPS® ID: 86601254949346

Affiliation

National Cancer Institute, National Institutes of Health, Bethesda, United States

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

3,142

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Drug repositioning strategy for the identification of novel telomere‐damaging agents: A role for NAMPT inhibitors (journal article) Rizzo, Angela \| Maresca, Carmen \| D'Angelo, Carmen \| Porru, Manuela \| Di Vito, Serena \| Salvati, Erica \| Sacconi, Andrea \| Berardinelli, Francesco \| Sgura, Antonella \| Kuznetsov, Sergey \| ... \| Biroccio, Annamaria Aging Cell, volume 22, issue 11 (2023). 10.1111/acel.13944 Cite \| Source
MiR ‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer (journal article) Dinami, Roberto \| Pompili, Luca \| Petti, Eleonora \| Porru, Manuela \| D'Angelo, Carmen \| Di Vito, Serena \| Rizzo, Angela \| Campani, Virginia \| De Rosa, Giuseppe \| Bruna, Alejandra \| ... \| Biroccio, Annamaria EMBO Molecular Medicine, volume 15, issue 1 (2023). 10.15252/emmm.202216033 Cited by (17) \| Cite \| Source
Hybrid Self-Assembling Nanoparticles Encapsulating Zoledronic Acid: A Strategy for Fostering Their Clinical Use (journal article) Abate, Marianna \| Scotti, Lorena \| Nele, Valeria \| Caraglia, Michele \| Biondi, Marco \| De Rosa, Giuseppe \| Leonetti, Carlo \| Campani, Virginia \| Zappavigna, Silvia \| Porru, Manuela International Journal of Molecular Sciences, volume 23, issue 9, pages 5138- (2022). 10.3390/ijms23095138 Cited by (5) \| Cite \| Source
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer (journal article) Dinami, Roberto \| Petti, Eleonora \| Porru, Manuela \| Rizzo, Angela \| Ganci, Federica \| Sacconi, Andrea \| Ostano, Paola \| Chiorino, Giovanna \| Trusolino, Livio \| Blandino, Giovanni \| ... \| Biroccio, Annamaria Cancer Letters, volume 533 (2022). 10.1016/j.canlet.2022.215607 Cited by (11) \| Cite \| Source
Anti‐tumoural activity of the G‐quadruplex ligand pyridostatin against BRCA1/2‐deficient tumours (journal article) Groelly, Florian J \| Porru, Manuela \| Zimmer, Jutta \| Benainous, Hugo \| De Visser, Yanti \| Kosova, Anastasiya A \| Di Vito, Serena \| Serra, Violeta \| Ryan, Anderson \| Leonetti, Carlo \| ... \| Tarsounas, Madalena EMBO Molecular Medicine, volume 14, issue 3 (2022). 10.15252/emmm.202114501 Cited by (17) \| Cite \| Source
Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects (journal article) Romito, Ilaria \| Porru, Manuela \| Braghini, Maria Rita \| Pompili, Luca \| Panera, Nadia \| Crudele, Annalisa \| Gnani, Daniela \| De Stefanis, Cristiano \| Scarsella, Marco \| Pomella, Silvia \| ... \| Alisi, Anna Journal of Experimental & Clinical Cancer Research, volume 40, issue 1 (2021). 10.1186/s13046-021-02154-8 Cited by (15) \| Cite \| Source
FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma (journal article) Cristinziano, Giulia \| Porru, Manuela \| Lamberti, Dante \| Buglioni, Simonetta \| Rollo, Francesca \| Amoreo, Carla Azzurra \| Manni, Isabella \| Giannarelli, Diana \| Cristofoletti, Cristina \| Russo, Giandomenico \| ... \| Segatto, Oreste Journal of Hepatology, volume 75, issue 2, pages 351-362 (2021). 10.1016/j.jhep.2021.02.032 Cited by (35) \| Cite \| Source
TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients (journal article) Dinami, Roberto \| Porru, Manuela \| Amoreo, Carla Azzurra \| Sperduti, Isabella \| Mottolese, Marcella \| Buglioni, Simonetta \| Marinelli, Daniele \| Maugeri-Saccà, Marcello \| Sacconi, Andrea \| Blandino, Giovanni \| ... \| Zizza, Pasquale Journal of Experimental & Clinical Cancer Research, volume 39, issue 1 (2020). 10.1186/s13046-020-01612-z Cited by (15) \| Cite \| Source
Hybrid lipid self-assembling nanoparticles for brain delivery of microRNA (journal article) Campani, Virginia \| Zappavigna, Silvia \| Scotti, Lorena \| Abate, Marianna \| Porru, Manuela \| Leonetti, Carlo \| Caraglia, Michele \| De Rosa, Giuseppe International Journal of Pharmaceutics, volume 588 (2020). 10.1016/j.ijpharm.2020.119693 Cited by (22) \| Cite \| Source
Harnessing Omics Approaches on Advanced Preclinical Models to Discovery Novel Therapeutic Targets for the Treatment of Metastatic Colorectal Cancer (journal article) Porru, Manuela \| Zizza, Pasquale \| Panera, Nadia \| Alisi, Anna \| Biroccio, Annamaria \| Leonetti, Carlo Cancers, volume 12, issue 7, pages 1830- (2020). 10.3390/cancers12071830 Cited by (2) \| Cite \| Source
Circulating miRNAs in Small Extracellular Vesicles Secreted by a Human Melanoma Xenograft in Mouse Brains (journal article) Guglielmi, Loredana \| Nardella, Marta \| Musa, Carla \| Cifola, Ingrid \| Porru, Manuela \| Cardinali, Beatrice \| Iannetti, Ilaria \| Di Pietro, Chiara \| Bolasco, Giulia \| Palmieri, Valentina \| ... \| D’Agnano, Igea Cancers, volume 12, issue 6, pages 1635- (2020). 10.3390/cancers12061635 Cited by (9) \| Cite \| Source
BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors (journal article) Reisländer, Timo \| Lombardi, Emilia Puig \| Groelly, Florian J. \| Miar, Ana \| Porru, Manuela \| Di Vito, Serena \| Wright, Benjamin \| Lockstone, Helen \| Biroccio, Annamaria \| Harris, Adrian \| ... \| Tarsounas, Madalena Nature Communications, volume 10, issue 1 (2019). 10.1038/s41467-019-11048-5 Cited by (134) \| Cite \| Source
Chlorambucil targets BRCA 1/2‐deficient tumours and counteracts PARP inhibitor resistance (journal article) Tacconi, Eliana MC \| Badie, Sophie \| De Gregoriis, Giuliana \| Reisländer, Timo \| Lai, Xianning \| Porru, Manuela \| Folio, Cecilia \| Moore, John \| Kopp, Arnaud \| Baguña Torres, Júlia \| ... \| Tarsounas, Madalena EMBO Molecular Medicine, volume 11, issue 7 (2019). 10.15252/emmm.201809982 Cited by (27) \| Cite \| Source
TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment (journal article) Zizza, Pasquale \| Dinami, Roberto \| Porru, Manuela \| Cingolani, Chiara \| Salvati, Erica \| Rizzo, Angela \| D’Angelo, Carmen \| Petti, Eleonora \| Amoreo, Carla Azzurra \| Mottolese, Marcella \| ... \| Biroccio, Annamaria Nucleic Acids Research (2019). 10.1093/nar/gkz041 Cited by (32) \| Cite \| Source
Combined therapy with Sorafenib and FAK inhibitor TAE226 impairs hepatocellular carcinoma growth by interfering with epigenetic modifications and stemness markers (journal article) Romito, I. \| Braghini, R. \| Panera, N. \| Pompili, L. \| Crudele, A. \| De Stefanis, C. \| Porru, M. \| Leonetti, C. \| Alisi, A. Digestive and Liver Disease, volume 51 (2019). 10.1016/j.dld.2018.11.102 Cite \| Source
HSP90 Inhibition Drives Degradation of FGFR2 Fusion Proteins: Implications for Treatment of Cholangiocarcinoma (journal article) Lamberti, Dante \| Cristinziano, Giulia \| Porru, Manuela \| Leonetti, Carlo \| Egan, Jan B. \| Shi, Chang‐Xin \| Buglioni, Simonetta \| Amoreo, Carla A. \| Castellani, Loriana \| Borad, Mitesh J. \| ... \| Segatto, Oreste Hepatology, volume 69, issue 1, pages 131-142 (2019). 10.1002/hep.30127 Cited by (25) \| Cite \| Source
Targeting KRAS in metastatic colorectal cancer: current strategies and emerging opportunities (journal article) Porru, Manuela \| Pompili, Luca \| Caruso, Carla \| Biroccio, Annamaria \| Leonetti, Carlo Journal of Experimental & Clinical Cancer Research, volume 37, issue 1 (2018). 10.1186/s13046-018-0719-1 Cited by (130) \| Cite \| Source \| Open Access
Chitosan-Based Polyelectrolyte Complexes for Doxorubicin and Zoledronic Acid Combined Therapy to Overcome Multidrug Resistance (journal article) Giarra, Simona \| Zappavigna, Silvia \| Campani, Virginia \| Abate, Marianna \| Cossu, Alessia Maria \| Leonetti, Carlo \| Porru, Manuela \| Mayol, Laura \| Caraglia, Michele \| De Rosa, Giuseppe Pharmaceutics, volume 10, issue 4, pages 180- (2018). 10.3390/pharmaceutics10040180 Cited by (10) \| Cite \| Source
Adipose-derived stem cell-mediated paclitaxel delivery inhibits breast cancer growth (journal article) Scioli, Maria Giovanna \| Artuso, Simona \| D'Angelo, Carmen \| Porru, Manuela \| D’Amico, Federico \| Bielli, Alessandra \| Gentile, Pietro \| Cervelli, Valerio \| Leonetti, Carlo \| Orlandi, Augusto PLOS ONE, volume 13, issue 9, pages e0203426- (2018). 10.1371/journal.pone.0203426 Cited by (31) \| Cite \| Source \| Open Access
Xenograft as In Vivo Experimental Model (book chapter) In Cancer Stem Cells Porru, Manuela \| Pompili, Luca \| Caruso, Carla \| Leonetti, Carlo Springer New York (2018) 10.1007/978-1-4939-7401-6_9 Cited by (3) \| Cite \| Source