Simon A. Hinke

ScholarGPS® ID: 86530383946374

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Medicine

Discipline

Cardiology

Top Specialties

Antibody

Metrics Summary

Publication Count

Predicted Citations

106

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Combination Therapy with Lisinopril and Dapagliflozin Rescues GFR Decline and Glomerular Damage in the KKAy Mouse Model of Diabetic Kidney Disease (journal article) Van Koppen, Arianne \| Nawrocki, Andrea R. \| Hinke, Simon A. \| Goor, Harry van \| Bajema, Ingeborg M. \| Dendooven, Amélie \| Nguyen, Tri Q. \| Breyer, Matthew D. \| Stoop, Reinout Journal of the American Society of Nephrology, volume 34, issue 11S, pages 844-844 (2023). 10.1681/ASN.20233411S1844a Cite \| Source
The Mouse Nephrotoxic Serum (NTS) Model to Screen Novel Drugs for Reversal of Podocyte Injury (journal article) Hinke, Simon A. \| Cavanaugh, Cassandre \| Rankin, Matthew M. \| Meng, Rong \| D’Aquino, Katharine \| Pissios, Pavlos \| Nawrocki, Andrea R. Journal of the American Society of Nephrology, volume 34, issue 11S, pages 301-301 (2023). 10.1681/ASN.20233411S1301a Cite \| Source
Diet Modification to Drive Fibrotic Response in Diabetic Kidney Disease (DKD) Model (journal article) Cavanaugh, Cassandre \| Hinke, Simon A. \| Rankin, Matthew M. \| Meng, Rong \| Shukla, Neetu \| Nawrocki, Andrea R. Journal of the American Society of Nephrology, volume 34, issue 11S, pages 494-494 (2023). 10.1681/ASN.20233411S1494d Cite \| Source
Diabetic Kidney Disease (DKD)-Induced Cardiac Damage Is Characterized and Reduced by Standard-of-Care Treatment in a Translational Diet-Induced Hypertension-Accelerated Mouse Model of DKD (journal article) Van Koppen, Arianne \| Nawrocki, Andrea R. \| Hinke, Simon A. \| Goor, Harry van \| Dendooven, Amélie \| Nguyen, Tri Q. \| Breyer, Matthew D. \| Stoop, Reinout Journal of the American Society of Nephrology, volume 34, issue 11S, pages 512-512 (2023). 10.1681/ASN.20233411S1512b Cite \| Source
Design, synthesis and preclinical evaluation of bio-conjugated amylinomimetic peptides as long-acting amylin receptor agonists (journal article) Patch, Raymond J. \| Zhang, Rui \| Edavettal, Suzanne \| Macielag, Mark J. \| Eckardt, Annette J. \| Li, Jiali \| Rives, Marie-Laure \| Edwards, Wilson \| Hinke, Simon A. \| Qiu, Xi \| ... \| Hornby, Pamela European Journal of Medicinal Chemistry, volume 236 (2022). 10.1016/j.ejmech.2022.114330 Cited by (2) \| Cite \| Source
Declining GFR and Advanced Pathology in a Translational Mouse Model of Diabetic Kidney Disease (journal article) Van Koppen, Arianne \| Nawrocki, Andrea R. \| Nguyen, Tri Q. \| Hinke, Simon A. \| Stoop, Reinout Journal of the American Society of Nephrology, volume 33, issue 11S, pages 664-664 (2022). 10.1681/ASN.20223311S1664a Cite \| Source
Effects of KCNN4 Blockade With Senicapoc in Kidney Cell-Based Assays and a Mouse Model of Renal Inflammation and Fibrosis (journal article) Zhou, Peng \| Hinke, Simon A. \| Cavanaugh, Cassandre \| Ma, Li-Jun \| Myshkin, Eugene \| Shukla, Neetu \| Natoli, Thomas A. \| Silva, Jose M. \| Magnone, Maria chiara \| Yang, Zhiyong Journal of the American Society of Nephrology, volume 33, issue 11S, pages 391-391 (2022). 10.1681/ASN.20223311S1391b Cite \| Source
1821-P: Foz Foz Mice with a Mutation in the Alms1 Gene Model the Metabolic Syndrome with Advanced Stages of Nonalcoholic Steatohepatitis and Fibrosis (journal article) LIU, Jianying \| Wang, Sheng-Ping \| D’AQUINO, Katharine E. \| HO, George \| Wallace, Nathaniel H. \| Rankin, Matthew M. \| DU, Fuyong \| Hinke, Simon A. \| Albarazanji, Kamal A. \| Nawrocki, Andrea R. Diabetes, volume 69, issue Supplement_1 (2020). 10.2337/db20-1821-P Cite \| Source
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors (journal article) Xu, Guozhang \| Gaul, Michael D. \| Kuo, Gee-Hong \| Du, Fuyong \| Xu, June Zhi \| Wallace, Nathaniel \| Hinke, Simon \| Kirchner, Thomas \| Silva, Jose \| Huebert, Norman D. \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 28, issue 21, pages 3446-3453 (2018). 10.1016/j.bmcl.2018.09.025 Cited by (9) \| Cite \| Source
Growth Differentiation Factor-15 (GDF-15) Inhibits Gastric Emptying in Rodents as Part of Its Anorectic Mechanism of Action (journal article) Hinke, Simon A. \| Cavanaugh, Cassandre R. \| Kirchner, Thomas \| Lang, Wensheng \| Meng, Rong \| Wallace, Nathaniel H. \| LIU, Jr. Jianying \| D'AQUINO, Katharine E. \| HO, George \| Rankin, Matthew M. \| ... \| Nawrocki, Andrea R. Diabetes, volume 67, issue Supplement_1 (2018). 10.2337/db18-283-LB Cited by (3) \| Cite \| Source
Potent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in Rodents (journal article) Du, Fuyong \| Hinke, Simon A. \| Cavanaugh, Cassandre \| Polidori, David \| Wallace, Nathanial \| Kirchner, Thomas \| Jennis, Matthew \| Lang, Wensheng \| Kuo, Gee-Hong \| Gaul, Micheal D. \| ... \| Hornby, Pamela J. Journal of Pharmacology and Experimental Therapeutics, volume 365, issue 3, pages 676-687 (2018). 10.1124/jpet.118.248575 Cited by (24) \| Cite \| Source
Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody (journal article) Hinke, Simon A. \| Cieniewicz, Anne M. \| Kirchner, Thomas \| D'Aquino, Katharine \| Nanjunda, Rupesh \| Aligo, Jason \| Perkinson, Robert \| Cooper, Philip \| Boayke, Ken \| Chiu, Mark L. \| ... \| Kihm, Anthony J. Molecular Metabolism, volume 10 (2018). 10.1016/j.molmet.2018.01.014 Cited by (14) \| Cite \| Source \| Open Access
Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance (journal article) Cieniewicz, Anne M. \| Kirchner, Thomas \| Hinke, Simon A. \| Nanjunda, Rupesh \| D’Aquino, Katharine \| Boayke, Ken \| Cooper, Philip R. \| Perkinson, Robert \| Chiu, Mark L. \| Jarantow, Stephen \| ... \| Kihm, Anthony J. Diabetes, volume 66, issue 1, pages 206-217 (2017). 10.2337/db16-0633 Cited by (10) \| Cite \| Source
State-Dependent Allosteric Inhibition of the Human SLC13A5 Citrate Transporter by Hydroxysuccinic Acids, PF-06649298 and PF-06761281 (journal article) Rives, Marie-Laure \| Shaw, Morena \| Zhu, Bin \| Hinke, Simon A. \| Wickenden, Alan D. Molecular Pharmacology, volume 90, issue 6, pages 766-774 (2016). 10.1124/mol.116.106575 Cited by (13) \| Cite \| Source