Andrea R. Nawrocki

ScholarGPS® ID: 84823309453204

Affiliation

Merck & Co., Inc., United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacology and Toxicology

Top Specialties

Insulin | Obesity | Insulin Resistance

Metrics Summary

Publication Count

Predicted Citations

4,383

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model (journal article) Zheng, Songmao \| Polidori, David \| Wang, Yuanping \| Geist, Brian \| Lin‐Schmidt, Xiefan \| Furman, Jennifer L. \| Nelson, Serena \| Nawrocki, Andrea R. \| Hinke, Simon A. Clinical and Translational Science, volume 16, issue 8, pages 1431-1444 (2023). 10.1111/cts.13543 Cited by (1) \| Cite \| Source
Diet Modification to Drive Fibrotic Response in Diabetic Kidney Disease (DKD) Model (journal article) Cavanaugh, Cassandre \| Hinke, Simon A. \| Rankin, Matthew M. \| Meng, Rong \| Shukla, Neetu \| Nawrocki, Andrea R. Journal of the American Society of Nephrology, volume 34, issue 11S, pages 494-494 (2023). 10.1681/ASN.20233411S1494d Cite \| Source
The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR (journal article) Steffen, Janos \| Ngo, Jennifer \| Wang, Sheng-Ping \| Williams, Kevin \| Kramer, Henning F. \| Ho, George \| Rodriguez, Carlos \| Yekkala, Krishna \| Amuzie, Chidozie \| Bialecki, Russell \| ... \| Liesa, Marc Molecular Metabolism, volume 64 (2022). 10.1016/j.molmet.2022.101566 Cited by (19) \| Cite \| Source
Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes (journal article) Palani, Anandan \| Nawrocki, Andrea R. \| Orvieto, Federica \| Bianchi, Elisabetta \| Mandić, Emanuela \| Pessi, Antonello \| Huang, Chunhui \| Deng, Qiaolin \| Toussaint, Nathalie \| Walsh, Erika \| ... \| Carrington, Paul E. ACS Medicinal Chemistry Letters, volume 13, issue 8, pages 1248-1254 (2022). 10.1021/acsmedchemlett.2c00217 Cited by (3) \| Cite \| Source
Diabetes and Obesity Increase the Severity of Ischemia-Reperfusion Induced AKI in ZSF1 Rats (journal article) Ma, Li-Jun \| Du, Fuyong \| Albarazanji, Kamal \| Liu, Jianying \| Li, Qiu \| Guo, Lili \| Qi, Jenson \| Ho, George \| Meng, Rong \| Chen, Tao \| ... \| Nawrocki, Andrea R. Journal of the American Society of Nephrology, volume 33, issue 11S, pages 74-74 (2022). 10.1681/ASN.20223311S174a Cite \| Source
1827-P: Pioglitazone Improves Nonalcoholic Steatohepatitis (NASH) in a Diet-Induced Cynomolgus Monkey Model (journal article) Camacho, Raul \| Polidori, David \| Chen, TAO \| GAO, BIN \| Wong, Peggy \| Gabriel, Joseph A. \| ZHU, Edward \| Wang, Tony \| Nawrocki, Andrea R. Diabetes, volume 69, issue Supplement_1 (2020). 10.2337/db20-1827-P Cited by (1) \| Cite \| Source
1821-P: Foz Foz Mice with a Mutation in the Alms1 Gene Model the Metabolic Syndrome with Advanced Stages of Nonalcoholic Steatohepatitis and Fibrosis (journal article) LIU, Jianying \| Wang, Sheng-Ping \| D’AQUINO, Katharine E. \| HO, George \| Wallace, Nathaniel H. \| Rankin, Matthew M. \| DU, Fuyong \| Hinke, Simon A. \| Albarazanji, Kamal A. \| Nawrocki, Andrea R. Diabetes, volume 69, issue Supplement_1 (2020). 10.2337/db20-1821-P Cite \| Source
FFAR1 Agonism Restores Insulin Secretion in Rodents, Human Islets, and Diabetic Monkeys (journal article) LIU, Jianying \| LEE, Seunghun P. \| Martin, Tonya \| Rady, Brian \| Meegalla, Sanath \| Huang, HUI \| Winters, Michael P. \| Norquay, Lisa D. \| QI, Jenson \| DU, Fuyong \| ... \| Pocai, Alessandro Diabetes, volume 67, issue Supplement_1 (2018). 10.2337/db18-609-P Cited by (1) \| Cite \| Source
Using [2 H]water to quantify the contribution of de novo palmitate synthesis in plasma: enabling back-to-back studies (journal article) Previs, Stephen F. \| Herath, Kithsiri \| Nawrocki, Andrea R. \| Rodriguez, Carlos G. \| Slipetz, Deborah \| Singh, Sheo B. \| Kang, Ling \| Bhat, Gowri \| Roddy, Thomas P. \| Conarello, Stacey \| ... \| Kelley, David E. American Journal of Physiology-Endocrinology and Metabolism, volume 315, issue 1, pages E63-E71 (2018). 10.1152/ajpendo.00010.2017 Cited by (10) \| Cite \| Source
Growth Differentiation Factor-15 (GDF-15) Inhibits Gastric Emptying in Rodents as Part of Its Anorectic Mechanism of Action (journal article) Hinke, Simon A. \| Cavanaugh, Cassandre R. \| Kirchner, Thomas \| Lang, Wensheng \| Meng, Rong \| Wallace, Nathaniel H. \| LIU, Jr. Jianying \| D'AQUINO, Katharine E. \| HO, George \| Rankin, Matthew M. \| ... \| Nawrocki, Andrea R. Diabetes, volume 67, issue Supplement_1 (2018). 10.2337/db18-283-LB Cited by (3) \| Cite \| Source
Glucagon like receptor 1/ glucagon dual agonist acutely enhanced hepatic lipid clearance and suppressed de novo lipogenesis in mice (journal article) More, Vijay R. \| Lao, Julie \| McLaren, David G. \| Cumiskey, Anne-Marie \| Murphy, Beth Ann \| Chen, Ying \| Previs, Stephen \| Stout, Steven \| Patel, Rajesh \| Satapati, Santhosh \| ... \| Carrington, Paul PLOS ONE, volume 12, issue 10, pages e0186586- (2017). 10.1371/journal.pone.0186586 Cited by (19) \| Cite \| Source \| Open Access
Decreased complexity of glucose dynamics preceding the onset of diabetes in mice and rats (journal article) Zhang, Xiaohua Douglas \| Pechter, David \| Yang, Liming \| Ping, Xiaoli \| Yao, Zuliang \| Zhang, Rumin \| Shen, Xiaolan \| Li, Nina Xiaoyan \| Connick, Jonathan \| Nawrocki, Andrea R. \| ... \| Li, Cai PLOS ONE, volume 12, issue 9, pages e0182810- (2017). 10.1371/journal.pone.0182810 Cited by (18) \| Cite \| Source \| Open Access
The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys (journal article) Singh, Sheo B. \| Kang, Ling \| Nawrocki, Andrea R. \| Zhou, Dan \| Wu, Margaret \| Previs, Stephen \| Miller, Corey \| Liu, Haiying \| Hines, Catherine D. G. \| Madeira, Maria \| ... \| Guan, Hong-Ping PLOS ONE, volume 11, issue 10, pages e0164133- (2016). 10.1371/journal.pone.0164133 Cited by (18) \| Cite \| Source \| Open Access
Quantifying fatty acid synthesis using heavy water: Enabling back‐to‐back studies (journal article) Previs, Stephen \| Herath, Kithsiri \| Nawrocki, Andrea \| Singh, Sheo \| Kang, Ling \| Erion, Mark \| Kelley, David The FASEB Journal, volume 30, issue S1 (2016). 10.1096/fasebj.30.1_supplement.684.18 Cite \| Source
Neurotensin Is Coexpressed, Coreleased, and Acts Together With GLP-1 and PYY in Enteroendocrine Control of Metabolism (journal article) Grunddal, Kaare V. \| Ratner, Cecilia F. \| Svendsen, Berit \| Sommer, Felix \| Engelstoft, Maja S. \| Madsen, Andreas N. \| Pedersen, Jens \| Nøhr, Mark K. \| Egerod, Kristoffer L. \| Nawrocki, Andrea R. \| ... \| Schwartz, Thue W. Endocrinology, volume 157, issue 1, pages 176-194 (2016). 10.1210/en.2015-1600 Cited by (118) \| Cite \| Source \| Open Access
Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance (journal article) Nawrocki, Andrea R. \| Rodriguez, Carlos G. \| Toolan, Dawn M. \| Price, Olga \| Henry, Melanie \| Forrest, Gail \| Szeto, Daphne \| Keohane, Carol Ann \| Pan, Yie \| Smith, Karen M. \| ... \| Smith, Sean M. Diabetes, volume 63, issue 1, pages 300-311 (2014). 10.2337/db13-0247 Cited by (38) \| Cite \| Source \| Open Access
Gender differences in adiponectin modulation of cardiac remodeling in mice deficient in endothelial nitric oxide synthase (journal article) Durand, Jorge L. \| Nawrocki, Andrea R. \| Scherer, Philipp E. \| Jelicks, Linda A. Journal of Cellular Biochemistry, volume 113, issue 10, pages 3276-3287 (2012). 10.1002/jcb.24206 Cited by (10) \| Cite \| Source \| Open Access
Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms (journal article) Lin, Hua V. \| Frassetto, Andrea \| Kowalik, Edward J. \| Nawrocki, Andrea R. \| Lu, Mofei M. \| Kosinski, Jennifer R. \| Hubert, James A. \| Szeto, Daphne \| Yao, Xiaorui \| Forrest, Gail \| Marsh, Donald J. PLoS ONE, volume 7, issue 4, pages e35240- (2012). 10.1371/journal.pone.0035240 Cited by (1,059) \| Cite \| Source \| Open Access
Effects of Peripherally Administered Neuromedin U on Energy and Glucose Homeostasis (journal article) Peier, Andrea M. \| Desai, Kunal \| Hubert, James \| Du, Xiaobing \| Yang, Liming \| Qian, Ying \| Kosinski, Jennifer R. \| Metzger, Joseph M. \| Pocai, Alessandro \| Nawrocki, Andrea R. \| ... \| Marsh, Donald J. Endocrinology, volume 152, issue 7, pages 2644-2654 (2011). 10.1210/en.2010-1463 Cited by (49) \| Cite \| Source \| Open Access
Short-Chain Fatty Acids Regulate Incretin Secretion and Protect Against Diet-Induced Obesity Via GPR41-Independent Mechanisms (book chapter) In BASIC/TRANSLATIONAL/CLINICAL - Late Breaking Research in Endocrinology Frassetto, Andrea \| Nawrocki, Andrea R \| Kowalik, Edward J \| Kosinski, Jennifer \| Hubert, James A \| Qatanani, Mohammed \| Xiong, Yusheng \| Cox, Jason M \| Lin, Hua V The Endocrine Society (2011) 10.1210/endo-meetings.2011.PART2.P20.P1-780 Cite \| Source