Zdzislaw M. Szulc

ScholarGPS® ID: 84553725528530

Affiliation

Medical University of South Carolina, Charleston, United States

Affiliation History

Field

Life Sciences

Discipline

Biochemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

7,012

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia (journal article) Ung, Johnson \| Tan, Su-Fern \| Fox, Todd E. \| Shaw, Jeremy J. P. \| Taori, Maansi \| Horton, Bethany J. \| Golla, Upendarrao \| Sharma, Arati \| Szulc, Zdzislaw M. \| Wang, Hong-Gang \| ... \| Feith, David J. Cancers, volume 15, issue 24, pages 5866- (2023). 10.3390/cancers15245866 Cite \| Source
Mitophagy As a Novel Cell-Protective Mechanism Against Mitochondrial Ferroptosis in Acute Myeloid Leukemia (journal article) Akiyama, Hiroki \| Tcheng, Matthew \| Sharma, Priyanka \| Zhao, Ran \| Ostermann, Lauren B. \| Yazdani, Samar \| Moayed, Arman \| Szulc, Zdzislaw \| Oleinik, Natalia \| Mak, Po Yee \| ... \| Ishizawa, Jo Blood, volume 142, issue Supplement 1, pages 2804-2804 (2023). 10.1182/blood-2023-181410 Cite \| Source
Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects (journal article) Oleinik, Natalia \| Albayram, Onder \| Kassir, Mohamed Faisal \| Atilgan, F. Cansu \| Walton, Chase \| Karakaya, Eda \| Kurtz, John \| Alekseyenko, Alexander \| Alsudani, Habeeb \| Sheridan, Megan \| ... \| Ogretmen, Besim Aging Cell, volume 22, issue 10 (2023). 10.1111/acel.13954 Cited by (1) \| Cite \| Source
Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis (journal article) Janneh, Alhaji H. \| Kassir, Mohamed Faisal \| Atilgan, F. Cansu \| Lee, Han Gyul \| Sheridan, Megan \| Oleinik, Natalia \| Szulc, Zdzislaw \| Voelkel-Johnson, Christina \| Nguyen, Hung \| Li, Hong \| ... \| Ogretmen, Besim Cell Reports, volume 41, issue 10, pages 111742- (2022). 10.1016/j.celrep.2022.111742 Cited by (6) \| Cite \| Source
Controlling Immunoregulatory Cell Activity for Effective Photodynamic Therapy of Cancer (book chapter) In Photodynamic Therapy Korbelik, Mladen \| Szulc, Zdzislaw M. \| Bielawska, Alicja \| Separovic, Duska Springer US (2022) 10.1007/978-1-0716-2099-1_28 Cited by (1) \| Cite \| Source
Crosstalk Between Pro-Survival Sphingolipid Metabolism and Complement Signaling Induces Inflammasome-Mediated Tumor Metastasis (journal article) Janneh, Alhaji H. \| Kassir, Mohamed Faisal \| Atilgan, F. Cansu \| Lee, Han Gyul \| Sheridan, Megan \| Oleinik, Natalia \| Szulc, Zdzislaw \| Voelkel-Johnson, Christina \| Nguyen, Hung \| Li, Hong \| ... \| Ogretmen, Besim SSRN Electronic Journal (2022). 10.2139/ssrn.4032074 Cite \| Source
Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer (journal article) Clifford, Rachael E. \| Govindarajah, Naren \| Bowden, David \| Sutton, Paul \| Glenn, Mark \| Darvish-Damavandi, Mahnaz \| Buczacki, Simon \| McDermott, Ultan \| Szulc, Zdzislaw \| Ogretmen, Besim \| ... \| Vimalachandran, Dale Cells, volume 9, issue 12, pages 2693- (2020). 10.3390/cells9122693 Cited by (15) \| Cite \| Source
Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis (journal article) Zhao, Dan \| Hajiaghamohseni, Laela M. \| Liu, Xiang \| Szulc, Zdzislaw M. \| Bai, Aiping \| Bielawska, Alicja \| Norris, James S. \| Reddy, Sakamuri V. \| Hannun, Yusuf A. \| Haque, Azizul Cytokine, volume 135 (2020). 10.1016/j.cyto.2020.155219 Cited by (4) \| Cite \| Source
Distinctive sphingolipid patterns in chronic multiple sclerosis lesions (journal article) Podbielska, Maria \| Szulc, Zdzislaw M. \| Ariga, Toshio \| Pokryszko-Dragan, Anna \| Fortuna, Wojciech \| Bilinska, Małgorzata \| Podemski, Ryszard \| Jaskiewicz, Ewa \| Kurowska, Ewa \| Yu, Robert K. \| Hogan, Edward L. Journal of Lipid Research, volume 61, issue 11, pages 1464-1479 (2020). 10.1194/jlr.RA120001022 Cited by (15) \| Cite \| Source
Mechanistic insights into ceramidase inhibitor LCL521-enhanced tumor cell killing by photodynamic and thermal ablation therapies (journal article) Korbelik, Mladen \| Zhao, Jianhua \| Zeng, Haishan \| Bielawska, Alicja \| Szulc, Zdzislaw M. Photochemical & Photobiological Sciences, volume 19, issue 9, pages 1145-1151 (2020). 10.1039/d0pp00116c Cited by (3) \| Cite \| Source
The NMR‐based characterization of the FTY720‐SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET‐PP2A interaction (journal article) De Palma, Ryan M. \| Parnham, Stuart R. \| Li, Yitong \| Oaks, Joshua J. \| Peterson, Yuri K. \| Szulc, Zdzislaw M. \| Roth, Braden M. \| Xing, Yongna \| Ogretmen, Besim The FASEB Journal, volume 33, issue 6, pages 7647-7666 (2019). 10.1096/fj.201802264R Cited by (30) \| Cite \| Source
Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA–dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis (journal article) Nganga, Rose \| Oleinik, Natalia \| Kim, Jisun \| Selvam, Shanmugam Panneer \| De Palma, Ryan \| Johnson, Kristen A. \| Parikh, Rasesh Y. \| Gangaraju, Vamsi \| Peterson, Yuri \| Dany, Mohammed \| ... \| Ogretmen, Besim Journal of Biological Chemistry, volume 294, issue 2, pages 502-519 (2019). 10.1074/jbc.RA118.005865 Cited by (22) \| Cite \| Source
C16-ceramide is a natural regulatory ligand of p53 in cellular stress response (journal article) Fekry, Baharan \| Jeffries, Kristen A. \| Esmaeilniakooshkghazi, Amin \| Szulc, Zdzislaw M. \| Knagge, Kevin J. \| Kirchner, David R. \| Horita, David A. \| Krupenko, Sergey A. \| Krupenko, Natalia I. Nature Communications, volume 9, issue 1 (2018). 10.1038/s41467-018-06650-y Cited by (72) \| Cite \| Source
Lipotoxic very‐long‐chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes (journal article) Law, Brittany A. \| Liao, Xianghai \| Moore, Kelsey S. \| Southard, Abigail \| Roddy, Patrick \| Ji, Ruiping \| Szulc, Zdzislaw \| Bielawska, Ala \| Schulze, P. Christian \| Cowart, L. Ashley The FASEB Journal, volume 32, issue 3, pages 1403-1416 (2018). 10.1096/fj.201700300R Cited by (139) \| Cite \| Source \| Open Access
Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression (journal article) Kim, Sungjin \| Alsaidan, Omar Awad \| Goodwin, Octavia \| Li, Qianjin \| Sulejmani, Essilvo \| Han, Zhen \| Bai, Aiping \| Albers, Thomas \| Beharry, Zanna \| Zheng, Y. George \| ... \| Cai, Houjian Cancer Research, volume 77, issue 24, pages 6950-6962 (2017). 10.1158/0008-5472.CAN-17-0981 Cited by (62) \| Cite \| Source
HPV /E7 induces chemotherapy‐mediated tumor suppression by ceramide‐dependent mitophagy (journal article) Thomas, Raquela J \| Oleinik, Natalia \| Panneer Selvam, Shanmugam \| Vaena, Silvia G \| Dany, Mohammed \| Nganga, Rose N \| Depalma, Ryan \| Baron, Kyla D \| Kim, Jisun \| Szulc, Zdzislaw M \| Ogretmen, Besim EMBO Molecular Medicine, volume 9, issue 8, pages 1030-1051 (2017). 10.15252/emmm.201607088 Cited by (45) \| Cite \| Source \| Open Access
Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase (journal article) Bai, Aiping \| Mao, Cungui \| Jenkins, Russell W. \| Szulc, Zdzislaw M. \| Bielawska, Alicja \| Hannun, Yusuf A. PLOS ONE, volume 12, issue 6, pages e0177805- (2017). 10.1371/journal.pone.0177805 Cited by (24) \| Cite \| Source \| Open Access
Ceramide synthesis regulates T cell activity and GVHD development (journal article) Sofi, M. Hanief \| Heinrichs, Jessica \| Dany, Mohammed \| Nguyen, Hung \| Dai, Min \| Bastian, David \| Schutt, Steven \| Wu, Yongxia \| Daenthanasanmak, Anusara \| Gencer, Salih \| ... \| Yu, Xue-Zhong JCI Insight, volume 2, issue 10 (2017). 10.1172/jci.insight.91701 Cited by (50) \| Cite \| Source \| Open Access
Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis (journal article) Pulkoski-Gross, Michael J. \| Uys, Joachim D. \| Orr-Gandy, K. Alexa \| Coant, Nicolas \| Bialkowska, Agnieszka B. \| Szulc, Zdzislaw M. \| Bai, Aiping \| Bielawska, Alicja \| Townsend, Danyelle M. \| Hannun, Yusuf A. \| ... \| Snider, Ashley J. Prostaglandins & Other Lipid Mediators, volume 130 (2017). 10.1016/j.prostaglandins.2017.03.006 Cited by (33) \| Cite \| Source \| Open Access
Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML (journal article) Dany, Mohammed \| Gencer, Salih \| Nganga, Rose \| Thomas, Raquela J. \| Oleinik, Natalia \| Baron, Kyla D. \| Szulc, Zdzislaw M. \| Ruvolo, Peter \| Kornblau, Steven \| Andreeff, Michael \| Ogretmen, Besim Blood, volume 128, issue 15, pages 1944-1958 (2016). 10.1182/blood-2016-04-708750 Cited by (135) \| Cite \| Source \| Open Access