Efstratios Stratikos

ScholarGPS® ID: 84275686694309

Affiliation

National and Kapodistrian University of Athens, Athens, Greece

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

3,690

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Library screening identifies commercial drugs as potential structure correctors of abnormal apolipoprotein A-I (journal article) Gkolfinopoulou, Christina \| Bourtsala, Angeliki \| Georgiadou, Daphne \| Dedemadi, Anastasia-Georgia \| Stratikos, Efstratios \| Chroni, Angeliki Journal of Lipid Research, volume 65, issue 5, pages 100543- (2024). 10.1016/j.jlr.2024.100543 Cite \| Source
Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase (journal article) Mpakali, Anastasia \| Barla, Ioanna \| Lu, Liying \| Ramesh, Karthik M. \| Thomaidis, Nikolaos \| Stern, Lawrence J. \| Giastas, Petros \| Stratikos, Efstratios Journal of Molecular Biology, volume 436, issue 6, pages 168449- (2024). 10.1016/j.jmb.2024.168449 Cited by (1) \| Cite \| Source
Distinct modulation of cellular immunopeptidome by the allosteric regulatory site of ER aminopeptidase 1 (journal article) Temponeras, Ioannis \| Samiotaki, Martina \| Koumantou, Despoina \| Nikopaschou, Martha \| Kuiper, Jonas J.W. \| Panayotou, George \| Stratikos, Efstratios European Journal of Immunology, volume 53, issue 8 (2023). 10.1002/eji.202350449 Cited by (1) \| Cite \| Source
Phosphinic Peptides as Tool Compounds for the Study of Pharmacologically Relevant Zn-Metalloproteases (journal article) Georgiadis, Dimitris \| Skoulikas, Nikolaos \| Papakyriakou, Athanasios \| Stratikos, Efstratios ACS Pharmacology & Translational Science, volume 5, issue 12, pages 1228-1253 (2022). 10.1021/acsptsci.2c00183 Cited by (1) \| Cite \| Source
Chemical inhibition of ER aminopeptidase 1 as a tool for regulating the immunopeptidome of cancer cells (journal article) Koumantou, Despoina \| Barnea, Eilon \| Martin-Esteban, Adrian \| Maben, Zachary \| Papakyriakou, Athanasios \| Kokkala, Paraskevi \| Pratsinis, Harris \| Georgiadis, Dimitris \| Stern, Lawrence J. \| Admon, Arie \| Stratikos, Efstratios Molecular Immunology, volume 150 (2022). 10.1016/j.molimm.2022.05.050 Cite \| Source
High-resolution crystal structures of ER aminopeptidase 1 with bound antigenic peptide precursor analogues (journal article) Giastas, Petros \| Lelis, Aggelos \| Kokkala, Paraskevi \| Georgiadis, Dimitris \| Stratikos, Efstratios Molecular Immunology, volume 150 (2022). 10.1016/j.molimm.2022.05.014 Cite \| Source
Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin (journal article) Vourloumis, Dionisios \| Mavridis, Ioannis \| Athanasoulis, Alexandros \| Temponeras, Ioannis \| Koumantou, Despoina \| Giastas, Petros \| Mpakali, Anastasia \| Magrioti, Victoria \| Leib, Jacqueline \| van Endert, Peter \| ... \| Papakyriakou, Athanasios Journal of Medicinal Chemistry, volume 65, issue 14, pages 10098-10117 (2022). 10.1021/acs.jmedchem.2c00904 Cited by (8) \| Cite \| Source
Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation (journal article) Papakyriakou, Athanasios \| Mpakali, Anastasia \| Stratikos, Efstratios Frontiers in Immunology, volume 13 (2022). 10.3389/fimmu.2022.863529 Cited by (5) \| Cite \| Source
Inhibitor-Dependent Usage of the S1′ Specificity Pocket of ER Aminopeptidase 2 (journal article) Mpakali, Anastasia \| Georgiadis, Dimitris \| Stratikos, Efstratios \| Giastas, Petros ACS Medicinal Chemistry Letters, volume 13, issue 2, pages 218-224 (2022). 10.1021/acsmedchemlett.1c00582 Cited by (2) \| Cite \| Source
ERAP2 Inhibition Induces Cell-Surface Presentation by MOLT-4 Leukemia Cancer Cells of Many Novel and Potentially Antigenic Peptides (journal article) Temponeras, Ioannis \| Stamatakis, George \| Samiotaki, Martina \| Georgiadis, Dimitris \| Pratsinis, Harris \| Panayotou, George \| Stratikos, Efstratios International Journal of Molecular Sciences, volume 23, issue 3, pages 1913- (2022). 10.3390/ijms23031913 Cited by (5) \| Cite \| Source
Tunable Hydrogels with Improved Viscoelastic Properties from Hybrid Polypeptides (journal article) Skoulas, Dimitrios \| Mangiapia, Gaetano \| Parisi, Daniele \| Kasimatis, Maria \| Glynos, Emmanouil \| Stratikos, Efstratios \| Vlassopoulos, Dimitris \| Frielinghaus, Henrich \| Iatrou, Hermis Macromolecules, volume 54, issue 23, pages 10786-10800 (2021). 10.1021/acs.macromol.1c01596 Cited by (10) \| Cite \| Source
Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein (journal article) Stamatakis, George \| Samiotaki, Martina \| Temponeras, Ioannis \| Panayotou, George \| Stratikos, Efstratios Journal of Biological Chemistry, volume 297, issue 5, pages 101329- (2021). 10.1016/j.jbc.2021.101329 Cited by (4) \| Cite \| Source
Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism (journal article) Maben, Zachary \| Arya, Richa \| Georgiadis, Dimitris \| Stratikos, Efstratios \| Stern, Lawrence J. Nature Communications, volume 12, issue 1 (2021). 10.1038/s41467-021-25564-w Cited by (19) \| Cite \| Source
The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class I (journal article) Mavridis, George \| Mpakali, Anastasia \| Zoidakis, Jerome \| Makridakis, Manousos \| Vlahou, Antonia \| Kaloumenou, Eleni \| Ziotopoulou, Angeliki \| Georgiadis, Dimitris \| Papakyriakou, Athanasios \| Stratikos, Efstratios Scientific Reports, volume 11, issue 1 (2021). 10.1038/s41598-021-95786-x Cited by (4) \| Cite \| Source
Discovery of Selective Inhibitor Leads by Targeting an Allosteric Site in Insulin-Regulated Aminopeptidase (journal article) Temponeras, Ioannis \| Chiniadis, Lykourgos \| Papakyriakou, Athanasios \| Stratikos, Efstratios Pharmaceuticals, volume 14, issue 6, pages 584- (2021). 10.3390/ph14060584 Cited by (5) \| Cite \| Source
A Carbodiimide-Mediated P–C Bond-Forming Reaction: Mild Amidoalkylation of P -Nucleophiles by Boc-Aminals (journal article) Kokkala, Paraskevi \| Rajeshkumar, Thayalan \| Mpakali, Anastasia \| Stratikos, Efstratios \| Vogiatzis, Konstantinos D. \| Georgiadis, Dimitris Organic Letters, volume 23, issue 5, pages 1726-1730 (2021). 10.1021/acs.orglett.1c00155 Cited by (7) \| Cite \| Source
ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29 (journal article) Venema, Wouter J. \| Hiddingh, Sanne \| de Boer, Joke H. \| Claas, Frans H. J. \| Mulder, Arend \| den Hollander, Anneke I. \| Stratikos, Efstratios \| Sarkizova, Siranush \| van der Veken, Lars T. \| Janssen, George M. C. \| ... \| Kuiper, Jonas J. W. Frontiers in Immunology, volume 12 (2021). 10.3389/fimmu.2021.634441 Cited by (15) \| Cite \| Source
Structure–function analysis of naturally occurring apolipoprotein A-I L144R, A164S and L178P mutants provides insight on their role on HDL levels and cardiovascular risk (journal article) Gkolfinopoulou, Christina \| Soukou, Faye \| Dafnis, Ioannis \| Kellici, Tahsin F. \| Sanoudou, Despina \| Mavromoustakos, Thomas \| Stratikos, Efstratios \| Chroni, Angeliki Cellular and Molecular Life Sciences, volume 78, issue 4, pages 1523-1544 (2021). 10.1007/s00018-020-03583-y Cited by (11) \| Cite \| Source
Common allotypes of ER aminopeptidase 1 have substrate-dependent and highly variable enzymatic properties (journal article) Hutchinson, Jonathan P. \| Temponeras, Ioannis \| Kuiper, Jonas \| Cortes, Adrian \| Korczynska, Justyna \| Kitchen, Semra \| Stratikos, Efstratios Journal of Biological Chemistry, volume 296 (2021). 10.1016/j.jbc.2021.100443 Cited by (16) \| Cite \| Source
The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy (journal article) Mpakali, Anastasia \| Stratikos, Efstratios Cancers, volume 13, issue 1, pages 134- (2021). 10.3390/cancers13010134 Cited by (69) \| Cite \| Source