René Maehr

ScholarGPS® ID: 83039138005115

Affiliation

University of Massachusetts Medical School, Worcester, United States

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

12,382

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Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
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NIH/NSF

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Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA–protein condensates (journal article) Chen, Yongzhi \| Lei, Xuqiu \| Jiang, Zhaozhao \| Humphries, Fiachra \| Parsi, Krishna Mohan \| Mustone, Nicholas J. \| Ramos, Irene \| Mutetwa, Tinaye \| Fernandez-Sesma, Ana \| Maehr, René \| ... \| Fitzgerald, Katherine A. Proceedings of the National Academy of Sciences, volume 120, issue 47 (2023). 10.1073/pnas.2308355120 Cited by (4) \| Cite \| Source
Generation and molecular characterization of human pluripotent stem cell-derived pharyngeal foregut endoderm (journal article) Kearns, Nicola A. \| Lobo, Macrina \| Genga, Ryan M.J. \| Abramowitz, Ryan G. \| Parsi, Krishna M. \| Min, Jiang \| Kernfeld, Eric M. \| Huey, Jack D. \| Kady, Jamie \| Hennessy, Erica \| ... \| Maehr, René Developmental Cell, volume 58, issue 18, pages 1801-1818.e15 (2023). 10.1016/j.devcel.2023.08.024 Cited by (1) \| Cite \| Source
Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish (journal article) Frantz, William Tyler \| Iyengar, Sharanya \| Neiswender, James \| Cousineau, Alyssa \| Maehr, René \| Ceol, Craig J eLife, volume 12 (2023). 10.7554/eLife.78942 Cited by (1) \| Cite \| Source
iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling (journal article) Guo, Dongsheng \| Daman, Katelyn \| Chen, Jennifer JC \| Shi, Meng-Jiao \| Yan, Jing \| Matijasevic, Zdenka \| Rickard, Amanda M \| Bennett, Monica H \| Kiselyov, Alex \| Zhou, Haowen \| ... \| Emerson, Charles P eLife, volume 11 (2022). 10.7554/eLife.70341 Cited by (9) \| Cite \| Source
Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development (journal article) Magaletta, Margaret E. \| Lobo, Macrina \| Kernfeld, Eric M. \| Aliee, Hananeh \| Huey, Jack D. \| Parsons, Teagan J. \| Theis, Fabian J. \| Maehr, René Nature Communications, volume 13, issue 1 (2022). 10.1038/s41467-022-28067-4 Cited by (18) \| Cite \| Source
SARS-CoV-2 Initiates Programmed Cell Death in Platelets (journal article) Koupenova, Milka \| Corkrey, Heather A. \| Vitseva, Olga \| Tanriverdi, Kahraman \| Somasundaran, Mohan \| Liu, Ping \| Soofi, Shaukat \| Bhandari, Rohan \| Godwin, Matthew \| Parsi, Krishna Mohan \| ... \| Freedman, Jane E. Circulation Research, volume 129, issue 6, pages 631-646 (2021). 10.1161/CIRCRESAHA.121.319117 Cited by (128) \| Cite \| Source
Systematic evaluation of chromosome conformation capture assays (journal article) Akgol Oksuz, Betul \| Yang, Liyan \| Abraham, Sameer \| Venev, Sergey V. \| Krietenstein, Nils \| Parsi, Krishna Mohan \| Ozadam, Hakan \| Oomen, Marlies E. \| Nand, Ankita \| Mao, Hui \| ... \| Dekker, Job Nature Methods, volume 18, issue 9, pages 1046-1055 (2021). 10.1038/s41592-021-01248-7 Cited by (87) \| Cite \| Source
A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection (journal article) Humphries, Fiachra \| Shmuel-Galia, Liraz \| Jiang, Zhaozhao \| Wilson, Ruth \| Landis, Philip \| Ng, Sze-Ling \| Parsi, Krishna Mohan \| Maehr, Rene \| Cruz, John \| Morales, Angel \| ... \| Fitzgerald, Katherine A. Science Immunology, volume 6, issue 59 (2021). 10.1126/sciimmunol.abi9002 Cited by (99) \| Cite \| Source
Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia (journal article) Reis, Monica \| Willis, Gareth R. \| Fernandez-Gonzalez, Angeles \| Yeung, Vincent \| Taglauer, Elizabeth \| Magaletta, Margaret \| Parsons, Teagan \| Derr, Alan \| Liu, Xianlan \| Maehr, Rene \| ... \| Mitsialis, S. Alex Frontiers in Immunology, volume 12 (2021). 10.3389/fimmu.2021.640595 Cited by (20) \| Cite \| Source
Ultrastructural Details of Mammalian Chromosome Architecture (journal article) Krietenstein, Nils \| Abraham, Sameer \| Venev, Sergey V. \| Abdennur, Nezar \| Gibcus, Johan \| Hsieh, Tsung-Han S. \| Parsi, Krishna Mohan \| Yang, Liyan \| Maehr, René \| Mirny, Leonid A. \| ... \| Rando, Oliver J. Molecular Cell, volume 78, issue 3, pages 554-565.e7 (2020). 10.1016/j.molcel.2020.03.003 Cited by (285) \| Cite \| Source
Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration (journal article) Han, Lu \| Choudhury, Sangita \| Mich-Basso, Jocelyn D. \| Ammanamanchi, Niyatie \| Ganapathy, Balakrishnan \| Suresh, Sangita \| Khaladkar, Mugdha \| Singh, Jennifer \| Maehr, Rene \| Zuppo, Daniel A. \| ... \| Kühn, Bernhard Developmental Cell, volume 53, issue 1, pages 42-59.e11 (2020). 10.1016/j.devcel.2020.01.030 Cited by (56) \| Cite \| Source
Combinatorial action of NF–Y and TALE at embryonic enhancers defines distinct gene expression programs during zygotic genome activation in zebrafish (journal article) Stanney, William \| Ladam, Franck \| Donaldson, Ian J. \| Parsons, Teagan J. \| Maehr, René \| Bobola, Nicoletta \| Sagerström, Charles G. Developmental Biology, volume 459, issue 2, pages 161-180 (2020). 10.1016/j.ydbio.2019.12.003 Cited by (7) \| Cite \| Source
Differentiation of human pluripotent stem cells toward pharyngeal endoderm derivatives: Current status and potential (book chapter) In Stem Cell Proliferation and Differentiation Magaletta, Margaret E. \| Siller, Richard \| Maehr, René Elsevier (2020) 10.1016/bs.ctdb.2020.01.004 Cited by (5) \| Cite \| Source
Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells (journal article) Min, So Yun \| Desai, Anand \| Yang, Zinger \| Sharma, Agastya \| DeSouza, Tiffany \| Genga, Ryan M. J. \| Kucukural, Alper \| Lifshitz, Lawrence M. \| Nielsen, Søren \| Scheele, Camilla \| ... \| Corvera, Silvia Proceedings of the National Academy of Sciences, volume 116, issue 36, pages 17970-17979 (2019). 10.1073/pnas.1906512116 Cited by (94) \| Cite \| Source
Inferring population dynamics from single-cell RNA-sequencing time series data (journal article) Fischer, David S. \| Fiedler, Anna K. \| Kernfeld, Eric M. \| Genga, Ryan M. J. \| Bastidas-Ponce, Aimée \| Bakhti, Mostafa \| Lickert, Heiko \| Hasenauer, Jan \| Maehr, Rene \| Theis, Fabian J. Nature Biotechnology, volume 37, issue 4, pages 461-468 (2019). 10.1038/s41587-019-0088-0 Cited by (66) \| Cite \| Source
Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development (journal article) Genga, Ryan M.J. \| Kernfeld, Eric M. \| Parsi, Krishna M. \| Parsons, Teagan J. \| Ziller, Michael J. \| Maehr, René Cell Reports, volume 27, issue 3, pages 708-718.e10 (2019). 10.1016/j.celrep.2019.03.076 Cited by (62) \| Cite \| Source
Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis (journal article) Phillips, Helen M. \| Stothard, Catherine A. \| Qureshi, Wasay Mohiuddin Shaikh \| Kousa, Anastasia I. \| Briones-Leon, J. Alberto \| Khasawneh, Ramada R. \| O'Loughlin, Chloe \| Sanders, Rachel \| Mazzotta, Silvia \| Dodds, Rebecca \| ... \| Bamforth, Simon D. Development (2019). 10.1242/dev.177618 Cited by (21) \| Cite \| Source
A Single-Cell Transcriptomic Atlas of Thymus Organogenesis Resolves Cell Types and Developmental Maturation (journal article) Kernfeld, Eric M. \| Genga, Ryan M.J. \| Neherin, Kashfia \| Magaletta, Margaret E. \| Xu, Ping \| Maehr, René Immunity, volume 48, issue 6, pages 1258-1270.e6 (2018). 10.1016/j.immuni.2018.04.015 Cited by (131) \| Cite \| Source
Beyond pseudotime: Following T-cell maturation in single-cell RNAseq time series (journal article) Fischer, David Sebastian \| Fiedler, Anna \| Kernfeld, Eric M. \| Genga, Ryan M. J. \| Hasenauer, Jan \| Maehr, René \| Theis, Fabian J. bioRxiv (2017). 10.1101/219188 Cited by (4) \| Cite \| Source \| Open Access
Using an Inducible CRISPR-dCas9-KRAB Effector System to Dissect Transcriptional Regulation in Human Embryonic Stem Cells (book chapter) In Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation Parsi, Krishna Mohan \| Hennessy, Erica \| Kearns, Nicola \| Maehr, René Springer New York (2017) 10.1007/978-1-4939-6518-2_16 Cited by (29) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Humanized Mouse Avatars for T1D	Brehm, Michael Allen \| Daley, George Q \| Greiner, Dale Leslie \| Kent, Sally Choate \| Maehr, Rene \| Melton, Douglas A \| Shultz, Leonard	2020	$1,011,466	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Humanized Mouse Avatars for T1D	Brehm, Michael Allen \| Daley, George Q \| Greiner, Dale Leslie \| Kent, Sally Choate \| Maehr, Rene \| Melton, Douglas A \| Shultz, Leonard	2019	$1,064,644	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Deciphering the molecular basis of T1D in human cells using functional genomics	Meissner, ALEXANDER (contact) \| Ziller, Michael \| Maehr, Rene \| Carr, Steven A	2016	$4,160,310	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Using pluripotent stem cells to study gene dosage-dependent immunodeficiency	Maehr, Rene	2015	$513,687	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES