Paola Di Lello

ScholarGPS® ID: 82395885987207

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Peptide | Ubiquitin | Zinc Finger | Antibody | Arabidopsis

Metrics Summary

Publication Count

Predicted Citations

1,878

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Incorporating NOE-Derived Distances in Conformer Generation of Cyclic Peptides with Distance Geometry (journal article) Wang, Shuzhe \| Krummenacher, Kajo \| Landrum, Gregory A. \| Sellers, Benjamin D. \| Di Lello, Paola \| Robinson, Sarah J. \| Martin, Bryan \| Holden, Jeffrey K. \| Tom, Jeffrey Y. K. \| Murthy, Anastasia C. \| ... \| Riniker, Sereina Journal of Chemical Information and Modeling, volume 62, issue 3, pages 472-485 (2022). 10.1021/acs.jcim.1c01165 Cited by (8) \| Cite \| Source
Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain (journal article) Ultsch, M. \| Li, W. \| Eigenbrot, C. \| Di Lello, P. \| Lipari, M.T. \| Gerhardy, S. \| AhYoung, A.P. \| Quinn, J. \| Franke, Y. \| Chen, Y. \| ... \| Kirchhofer, D. Journal of Molecular Biology, volume 431, issue 5, pages 885-903 (2019). 10.1016/j.jmb.2018.11.025 Cited by (8) \| Cite \| Source
Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques (journal article) Di Lello, Paola \| Pastor, Richard \| Murray, Jeremy M. \| Blake, Robert A. \| Cohen, Frederick \| Crawford, Terry D. \| Drobnick, Joy \| Drummond, Jason \| Kategaya, Lorna \| Kleinheinz, Tracy \| ... \| Tsui, Vickie Journal of Medicinal Chemistry, volume 60, issue 24, pages 10056-10070 (2017). 10.1021/acs.jmedchem.7b01293 Cited by (59) \| Cite \| Source
Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists (journal article) Zhang, Yingnan \| Ultsch, Mark \| Skelton, Nicholas J \| Burdick, Daniel J \| Beresini, Maureen H \| Li, Wei \| Kong-Beltran, Monica \| Peterson, Andrew \| Quinn, John \| Chiu, Cecilia \| ... \| Kirchhofer, Daniel Nature Structural & Molecular Biology, volume 24, issue 10, pages 848-856 (2017). 10.1038/nsmb.3453 Cited by (58) \| Cite \| Source
Structural Characterization of Recombinant Proteins and Antibodies (book chapter) In Analytical Characterization of Biotherapeutics Di Lello, Paola \| Lupardus, Patrick Wiley (2017) 10.1002/9781119384434.ch5 Cite \| Source
USP7 inhibitor compounds and methods of use (patent) Blake, Robert \| Di Lello, Paola \| Drummond, Jason \| Heideker, Christine Johanna \| Kategaya, Lorna \| Maurer, Till \| Murray, Jeremy M. \| Ndubaku, Chudi \| Pastor, Richard \| Rouge, Lionel \| ... \| Yu, Kebing Patent Number: 9573899 (2017) Cited by (1) \| Cite \| Source
Mitigation of reactive metabolite formation for a series of 3-amino-2-pyridone inhibitors of Bruton’s tyrosine kinase (BTK) (journal article) Lou, Yan \| Lopez, Francisco \| Jiang, Yongying \| Han, Xiaochun \| Brotherton, Chris \| Billedeau, Roland \| Gabriel, Steve \| Gleason, Shelly \| Goldstein, David M. \| Hilgenkamp, Ramona \| ... \| Owens, Timothy D. Bioorganic & Medicinal Chemistry Letters, volume 27, issue 3, pages 632-635 (2017). 10.1016/j.bmcl.2016.11.092 Cited by (8) \| Cite \| Source
1H, 13C and 15N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7) (journal article) Di Lello, Paola \| Rougé, Lionel \| Pan, Borlan \| Maurer, Till Biomolecular NMR Assignments, volume 10, issue 2, pages 345-349 (2016). 10.1007/s12104-016-9698-3 Cited by (3) \| Cite \| Source
Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation (journal article) Rougé, Lionel \| Bainbridge, Travis W. \| Kwok, Michael \| Tong, Raymond \| Di Lello, Paola \| Wertz, Ingrid E. \| Maurer, Till \| Ernst, James A. \| Murray, Jeremy Structure, volume 24, issue 8, pages 1335-1345 (2016). 10.1016/j.str.2016.05.020 Cited by (67) \| Cite \| Source \| Open Access
Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies (journal article) Burger, Dominique \| Stihle, Martine \| Sharma, Ashwani \| Di Lello, Paola \| Benz, Jörg \| D'Arcy, Brigitte \| Debulpaep, Maja \| Fry, David \| Huber, Walter \| Kremer, Thomas \| ... \| Ruf, Armin Journal of Biological Chemistry, volume 291, issue 31, pages 16292-16306 (2016). 10.1074/jbc.M116.726547 Cited by (11) \| Cite \| Source \| Open Access
Unveiling the Structural and Dynamic Nature of the Ubiquitin Code (journal article) Di Lello, Paola \| Hymowitz, Sarah G. Structure, volume 24, issue 4, pages 498-499 (2016). 10.1016/j.str.2016.03.013 Cited by (2) \| Cite \| Source \| Open Access
Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor (journal article) Zhang, Yingnan \| Eigenbrot, Charles \| Zhou, Lijuan \| Shia, Steven \| Li, Wei \| Quan, Clifford \| Tom, Jeffrey \| Moran, Paul \| Di Lello, Paola \| Skelton, Nicholas J. \| ... \| Kirchhofer, Daniel Journal of Biological Chemistry, volume 289, issue 2, pages 942-955 (2014). 10.1074/jbc.M113.514067 Cited by (138) \| Cite \| Source \| Open Access
Design of Libraries Targeting Protein–Protein Interfaces (journal article) Fry, David \| Huang, Kuo‐Sen \| Di Lello, Paola \| Mohr, Peter \| Müller, Klaus \| So, Sung‐Sau \| Harada, Takeo \| Stahl, Martin \| Vu, Binh \| Mauser, Harald ChemMedChem, volume 8, issue 5, pages 726-732 (2013). 10.1002/cmdc.201200540 Cited by (31) \| Cite \| Source
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization (journal article) Graves, Bradford \| Thompson, Thelma \| Xia, Mingxuan \| Janson, Cheryl \| Lukacs, Christine \| Deo, Dayanand \| Di Lello, Paola \| Fry, David \| Garvie, Colin \| Huang, Kuo-Sen \| ... \| Vassilev, Lyubomir T. Proceedings of the National Academy of Sciences, volume 109, issue 29, pages 11788-11793 (2012). 10.1073/pnas.1203789109 Cited by (190) \| Cite \| Source \| Open Access
The Organomercurial Lyase Mer B (book chapter) In Encyclopedia of Inorganic and Bioinorganic Chemistry Lello, Paola Di \| Lafrance‐Vanasse, Julien \| Omichinski, James G Wiley (2011) 10.1002/9781119951438.eibc0694 Cited by (2) \| Cite \| Source
Structural and functional characterization of an atypical activation domain in erythroid Krüppel-like factor (EKLF) (journal article) Mas, Caroline \| Lussier-Price, Mathieu \| Soni, Shefali \| Morse, Thomas \| Arseneault, Geneviève \| Di Lello, Paola \| Lafrance-Vanasse, Julien \| Bieker, James J. \| Omichinski, James G. Proceedings of the National Academy of Sciences, volume 108, issue 26, pages 10484-10489 (2011). 10.1073/pnas.1017029108 Cited by (44) \| Cite \| Source \| Open Access
A Conserved Amphipathic Helix in the N-Terminal Regulatory Region of the Papillomavirus E1 Helicase Is Required for Efficient Viral DNA Replication (journal article) Morin, Geneviève \| Fradet-Turcotte, Amélie \| Di Lello, Paola \| Bergeron-Labrecque, Fanny \| Omichinski, James G. \| Archambault, Jacques Journal of Virology, volume 85, issue 11, pages 5287-5300 (2011). 10.1128/JVI.01829-10 Cited by (22) \| Cite \| Source \| Open Access
GATA-1 associates with and inhibits p53 (journal article) Trainor, Cecelia D. \| Mas, Caroline \| Archambault, Patrick \| Di Lello, Paola \| Omichinski, James G. Blood, volume 114, issue 1, pages 165-173 (2009). 10.1182/blood-2008-10-180489 Cited by (44) \| Cite \| Source \| Open Access
Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease (journal article) Dikeakos, Jimmy D. \| Di Lello, Paola \| Lacombe, Marie-Josée \| Ghirlando, Rodolfo \| Legault, Pascale \| Reudelhuber, Timothy L. \| Omichinski, James G. Proceedings of the National Academy of Sciences, volume 106, issue 18, pages 7408-7413 (2009). 10.1073/pnas.0809576106 Cited by (36) \| Cite \| Source \| Open Access
NMR Structure of a Complex Formed by the Carboxyl-Terminal Domain of Human RAP74 and a Phosphorylated Peptide from the Central Domain of the FCP1 Phosphatase (journal article) Yang, Ao \| Abbott, Karen L. \| Desjardins, Alexandre \| Di Lello, Paola \| Omichinski, James G. \| Legault, Pascale Biochemistry, volume 48, issue 9, pages 1964-1974 (2009). 10.1021/bi801549m Cited by (14) \| Cite \| Source