Kai W. Wucherpfennig

ScholarGPS® ID: 82393978475593

Affiliation
Dana-Farber Cancer Institute, Boston, United States
Affiliation History

Field
Medicine
Discipline
Immunology
Top Specialties
Peptide | Cancer | Antigen | Neoplasm | Multiple Sclerosis | Autoimmunity | Immunotherapy | Infection | Autoimmune Disease | Diabetes | MHC Class II | Antibody | T-cell Receptor | Glioblastoma | Cancer Immunotherapy
Metrics Summary
Publication Count
278
Predicted Citations
35,674
Predicted h-index
101
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Targeting of the CD161 inhibitory receptor enhances T-cell–mediated immunity against hematological malignancies (journal article)
Alvarez Calderon, Francesca | Kang, Byong H. | Kyrysyuk, Oleksandr | Zheng, Shiwei | Wang, Hao | Mathewson, Nathan D. | Luoma, Adrienne M. | Ning, Xiaohan | Pyrdol, Jason | Cao, Xuan | ... | Wucherpfennig, Kai W.
Blood, volume 143, issue 12, pages 1124-1138 (2024).
10.1182/blood.2023022882
Cited by (2) | Cite | Source
MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors (journal article)
Verhaar, Elisha R. | Knoflook, Anouk | Pishesha, Novalia | Liu, Xin | van Keizerswaard, Willemijn J. C. | Wucherpfennig, Kai W. | Ploegh, Hidde L.
Frontiers in Immunology, volume 15 (2024).
10.3389/fimmu.2024.1368586
Cited by (1) | Cite | Source
Neoadjuvant immune checkpoint blockade enhances local and systemic tumor immunity in head and neck cancer (journal article)
Zhao, Ye | Wucherpfennig, Kai W.
Current Opinion in Oncology, volume 36, issue 3, pages 136-142 (2024).
10.1097/CCO.0000000000001023
Cite | Source
4-1bb Enrichment Enhances Adoptive T Cell Therapy for Hematological Malignancies Using a Novel Approach for Ex Vivo Immune Cell Priming with DC/Tumor Fusion Vaccine (journal article)
Rallis, Kathrine S | Liegel, Jessica | Cheloni, Giulia | Bindal, Poorva | Saldarriaga, Isabella | Zhang, Junyan | Chedid, Georges | Abirached, Joseph | Clohessy, John G. | Adamia, Sophia | ... | Avigan, David
Blood, volume 142, issue Supplement 1, pages 2066-2066 (2023).
10.1182/blood-2023-182381
Cite | Source
Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell–Secreted Cytokines (journal article)
Ito, Yoshinaga | Pan, Deng | Zhang, Wubing | Zhang, Xixi | Juan, Tiffany Y. | Pyrdol, Jason W. | Kyrysyuk, Oleksandr | Doench, John G. | Liu, X. Shirley | Wucherpfennig, Kai W.
Cancer Discovery, volume 13, issue 5, pages 1186-1209 (2023).
10.1158/2159-8290.CD-22-1125
Cited by (4) | Cite | Source
Designing Cancer Immunotherapies That Engage T Cells and NK Cells (journal article)
Kyrysyuk, Oleksandr | Wucherpfennig, Kai W.
Annual Review of Immunology, volume 41, issue 1, pages 17-38 (2023).
10.1146/annurev-immunol-101921-044122
Cited by (44) | Cite | Source
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer (journal article)
Hagel, Kimberly R. | Arafeh, Rand | Gang, Sydney | Arnoff, Taylor E. | Larson, Rebecca C. | Doench, John G. | Mathewson, Nathan D. | Wucherpfennig, Kai W. | Maus, Marcela V. | Hahn, William C.
Cancer Research, volume 83, issue 4, pages 613-625 (2023).
10.1158/0008-5472.CAN-22-2245
Cited by (7) | Cite | Source
Cytokine conjugation to enhance T cell therapy (journal article)
Liu, Yutong | Adu-Berchie, Kwasi | Brockman, Joshua M. | Pezone, Matthew | Zhang, David K.Y. | Zhou, Jingyi | Pyrdol, Jason W. | Wang, Hua | Wucherpfennig, Kai W. | Mooney, David J.
Proceedings of the National Academy of Sciences, volume 120, issue 1 (2023).
10.1073/pnas.2213222120
Cited by (23) | Cite | Source
MICA/B-targeted antibody promotes NK cell–driven tumor immunity in patients with intrahepatic cholangiocarcinoma (journal article)
Oliviero, Barbara | Varchetta, Stefania | Mele, Dalila | Pessino, Greta | Maiello, Roberta | Falleni, Monica | Tosi, Delfina | Donadon, Matteo | Soldani, Cristiana | Franceschini, Barbara | ... | Mantovani, Stefania
OncoImmunology, volume 11, issue 1 (2022).
10.1080/2162402X.2022.2035919
Cited by (12) | Cite | Source
A structural platform for B cell receptor signaling (journal article)
Xie, Wei | Wucherpfennig, Kai | Patel, Dinshaw J.
Cell Research, volume 33, issue 2, pages 95-96 (2022).
10.1038/s41422-022-00724-9
Cited by (2) | Cite | Source
A Conceptual Framework for Inducing T Cell-Mediated Immunity Against Glioblastoma (journal article)
Marx, Sascha | Godicelj, Anze | Wucherpfennig, Kai W.
Seminars in Immunopathology, volume 44, issue 5, pages 697-707 (2022).
10.1007/s00281-022-00945-5
Cited by (6) | Cite | Source
Mechanical checkpoint regulates monocyte differentiation in fibrotic niches (journal article)
Vining, Kyle H. | Marneth, Anna E. | Adu-Berchie, Kwasi | Grolman, Joshua M. | Tringides, Christina M. | Liu, Yutong | Wong, Waihay J. | Pozdnyakova, Olga | Severgnini, Mariano | Stafford, Alexander | ... | Mooney, David J.
Nature Materials, volume 21, issue 8, pages 939-950 (2022).
10.1038/s41563-022-01293-3
Cited by (25) | Cite | Source
A vaccine targeting resistant tumours by dual T cell plus NK cell attack (journal article)
Badrinath, Soumya | Dellacherie, Maxence O. | Li, Aileen | Zheng, Shiwei | Zhang, Xixi | Sobral, Miguel | Pyrdol, Jason W. | Smith, Kathryn L. | Lu, Yuheng | Haag, Sabrina | ... | Wucherpfennig, Kai W.
Nature, volume 606, issue 7916, pages 992-998 (2022).
10.1038/s41586-022-04772-4
Cited by (74) | Cite | Source
MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia (journal article)
Alves da Silva, Pedro Henrique | Xing, Samantha | Kotini, Andriana G. | Papapetrou, Eirini P. | Song, Xiaoyu | Wucherpfennig, Kai W. | Mascarenhas, John | Ferrari de Andrade, Lucas
Blood, volume 139, issue 2, pages 205-216 (2022).
10.1182/blood.2021011619
Cited by (22) | Cite | Source
TAMI-12. CANCER-IMMUNE CELL INTERACTIONS DRIVE TRANSITIONS TO MESENCHYMAL-LIKE STATES IN GLIOBLASTOMA (journal article)
Hara, Toshiro | Chanoch-Myers, Rony | Mathewson, Nathan | Myskiw, Chad | Atta, Lyla | Bussema, Lillian | Eichhorn, Stephen | Greenwald, Alissa | Kinker, Gabriela | Rodman, Christopher | ... | Tirosh, Itay
Neuro-Oncology, volume 23, issue Supplement_6, pages vi200-vi200 (2021).
10.1093/neuonc/noab196.796
Cite | Source
Dual Chimeric Antigen Receptor Approach Combining Novel Tumor Targeting Strategies Circumvents Antigen Escape in Multiple Myeloma (journal article)
Reiser, John | Mathavan, Ketan | Mahmood, Sajid | Pan, Yijia | Hancock, Bryan | Blum, Robert | Yeh, Wen-I | Houk, Andrew | Chang, Chia-Wei | Lee, Tom | ... | Valamehr, Bahram
Blood, volume 138, issue Supplement 1, pages 1718-1718 (2021).
10.1182/blood-2021-154025
Cited by (7) | Cite | Source
Mechanical Checkpoint Regulates Monocyte Differentiation in Fibrotic Matrix (journal article)
Vining, Kyle H | Marneth, Anna E. | Adu-Berchie, Kwasi | Tringides, Christina M. | Grolman, Joshua M | Liu, Yutong | Wong, Waihay J. | Pozdnyakova, Olga | Severgnini, Mariano | Stafford, Alexander | ... | Mooney, David J
Blood, volume 138, issue Supplement 1, pages 2539-2539 (2021).
10.1182/blood-2021-147297
Cited by (2) | Cite | Source
395 Detection of viral antigen and immune activation after intra-tumor injection of CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma (conference)
Barone, Francesca | Lawler, Sean | Aguilar, Laura | Dwyer, Jessica | Guzik, Brian | Soloman, Isaac | Nakashima, Hiroshi | Triggs, Daniel | Zhang, Abigail Tianai | Zeng, Yu | ... | Antonio Chiocca, E
SITC 36th Anniversary Annual Meeting (SITC 2021) Abstracts (2021)
10.1136/jitc-2021-SITC2021.395
Cite | Source
Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation (journal article)
Heckler, Max | Ali, Lestat R. | Clancy-Thompson, Eleanor | Qiang, Li | Ventre, Katherine S. | Lenehan, Patrick | Roehle, Kevin | Luoma, Adrienne | Boelaars, Kelly | Peters, Vera | ... | Dougan, Stephanie K.
Cancer Discovery, volume 11, issue 10, pages 2564-2581 (2021).
10.1158/2159-8290.CD-20-1540
Cited by (62) | Cite | Source
Systematic investigation of cytokine signaling activity at the tissue and single-cell levels (journal article)
Jiang, Peng | Zhang, Yu | Ru, Beibei | Yang, Yuan | Vu, Trang | Paul, Rohit | Mirza, Amer | Altan-Bonnet, Grégoire | Liu, Lingrui | Ruppin, Eytan | ... | Wucherpfennig, Kai W.
Nature Methods, volume 18, issue 10, pages 1181-1191 (2021).
10.1038/s41592-021-01274-5
Cited by (80) | Cite | Source