Christopher C. Arico-Muendel

ScholarGPS® ID: 81770626227371

Affiliation
GlaxoSmithKline plc, London
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Peptide | Medicinal Chemistry | DNA | Amyloid Beta | Analytical Chemistry
Metrics Summary
Publication Count
43
Predicted Citations
2,137
Predicted h-index
22
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
You must register and claim your profile to add or remove publications from it.
... publications
FILTER BY:
Year
Type
Specialty
Affiliations
Access
Co-Authors
Add
Delete
Synthesis of a DNA-Encoded Macrocyclic Library Utilizing Intramolecular Benzimidazole Formation (journal article)
Chai, Jing | Arico-Muendel, Christopher C. | Ding, Yun | Pollastri, Michael P. | Scott, Sarah | Mantell, Mark A. | Yao, Gang
Bioconjugate Chemistry, volume 34, issue 6, pages 988-993 (2023).
10.1021/acs.bioconjchem.3c00159
Cited by (4) | Cite | Source
Application of l -Threonine Aldolase to on-DNA Reactions (journal article)
Chai, Jing | Lu, Xiaojie | Arico-Muendel, Christopher C. | Ding, Yun | Pollastri, Michael P.
Bioconjugate Chemistry, volume 32, issue 9, pages 1973-1978 (2021).
10.1021/acs.bioconjchem.1c00363
Cited by (4) | Cite | Source
Randomness in DNA Encoded Library Selection Data Can Be Modeled for More Reliable Enrichment Calculation (journal article)
Kuai, Letian | O’Keeffe, Thomas | Arico-Muendel, Christopher
SLAS Discovery, volume 23, issue 5, pages 405-416 (2018).
10.1177/2472555218757718
Cited by (51) | Cite | Source
From haystack to needle: finding value with DNA encoded library technology at GSK (journal article)
Arico-Muendel, Christopher C.
MedChemComm, volume 7, issue 10, pages 1898-1909 (2016).
10.1039/C6MD00341A
Cited by (72) | Cite | Source
Predicting Electrophoretic Mobility of Protein–Ligand Complexes for Ligands from DNA-Encoded Libraries of Small Molecules (journal article)
Bao, Jiayin | Krylova, Svetlana M. | Cherney, Leonid T. | Hale, Robert L. | Belyanskaya, Svetlana L. | Chiu, Cynthia H. | Shaginian, Alex | Arico-Muendel, Christopher C. | Krylov, Sergey N.
Analytical Chemistry, volume 88, issue 10, pages 5498-5506 (2016).
10.1021/acs.analchem.6b00980
Cited by (30) | Cite | Source
Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors (journal article)
Deng, Hongfeng | Zhou, Jingye | Sundersingh, Flora | Messer, Jeffrey A. | Somers, Donald O. | Ajakane, Myriam | Arico-Muendel, Christopher C. | Beljean, Arthur | Belyanskaya, Svetlana L. | Bingham, Ryan | ... | Ancellin, Nicolas
ACS Medicinal Chemistry Letters, volume 7, issue 4, pages 379-384 (2016).
10.1021/acsmedchemlett.5b00389
Cited by (33) | Cite | Source | Open Access
Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT) (journal article)
Ding, Yun | O’Keefe, Heather | DeLorey, Jennifer L. | Israel, David I. | Messer, Jeffrey A. | Chiu, Cynthia H. | Skinner, Steven R. | Matico, Rosalie E. | Murray-Thompson, Monique F. | Li, Fan | ... | Morgan, Barry A.
ACS Medicinal Chemistry Letters, volume 6, issue 8, pages 888-893 (2015).
10.1021/acsmedchemlett.5b00138
Cited by (68) | Cite | Source | Open Access
Encoded Library Technology Screening of Hepatitis C Virus NS4B Yields a Small-Molecule Compound Series with In Vitro Replicon Activity (journal article)
Arico-Muendel, Christopher | Zhu, Zhengrong | Dickson, Hamilton | Parks, Derek | Keicher, Jesse | Deng, Jianghe | Aquilani, Leah | Coppo, Frank | Graybill, Todd | Lind, Kenneth | ... | Thomson, Michael
Antimicrobial Agents and Chemotherapy, volume 59, issue 6, pages 3450-3459 (2015).
10.1128/AAC.00070-15
Cited by (26) | Cite | Source | Open Access
Prediction of Protein–DNA Complex Mobility in Gel-Free Capillary Electrophoresis (journal article)
Bao, Jiayin | Krylova, Svetlana M. | Cherney, Leonid T. | Hale, Robert L. | Belyanskaya, Svetlana L. | Chiu, Cynthia H. | Arico-Muendel, Christopher C. | Krylov, Sergey N.
Analytical Chemistry, volume 87, issue 4, pages 2474-2479 (2015).
10.1021/ac504504c
Cited by (19) | Cite | Source
Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium tuberculosis InhA (journal article)
Encinas, Lourdes | O’Keefe, Heather | Neu, Margarete | Remuiñán, Modesto J. | Patel, Amish M. | Guardia, Ana | Davie, Christopher P. | Pérez-Macías, Natalia | Yang, Hongfang | Convery, Maire A. | ... | Evindar, Ghotas
Journal of Medicinal Chemistry, volume 57, issue 4, pages 1276-1288 (2014).
10.1021/jm401326j
Cited by (103) | Cite | Source | Open Access
Methods for synthesis of encoded libraries (patent)
Morgan, Barry | Arico-Muendel, Christopher C. | Israel, David I. | Benjamin, Dennis | Franklin, George J. | Kavarana, Malcolm J. | Gefter, Malcolm L. | Clark, Matthew | Hansen, Nils Jakob Vest | Centrella, Paolo A. | ... | Hale, Stephen
Patent Number: 8598089 (2013)
Cite | Source
Orally Active Fumagillin Analogues: Transformations of a Reactive Warhead in the Gastric Environment (journal article)
Arico-Muendel, Christopher C. | Blanchette, Heather | Benjamin, Dennis R. | Caiazzo, Teresa M. | Centrella, Paolo A. | DeLorey, Jennifer | Doyle, Elisabeth G. | Johnson, Steven R. | Labenski, Matthew T. | Morgan, Barry A. | ... | White, Kerry F.
ACS Medicinal Chemistry Letters, volume 4, issue 4, pages 381-386 (2013).
10.1021/ml3003633
Cited by (8) | Cite | Source | Open Access
Methods for synthesis of encoded libraries (patent)
Morgan, Barry | Arico-Muendel, Christopher C. | Israel, David I. | Benjamin, Dennis | Franklin, George J. | Kavarana, Malcolm J. | Gefter, Malcolm L. | Clark, Matthew | Hansen, Nils Jakob Vest | Centrella, Paolo A. | ... | Hale, Stephen
Patent Number: 8410028 (2013)
Cite | Source
Metabolites of PPI-2458, a Selective, Irreversible Inhibitor of Methionine Aminopeptidase-2: Structure Determination and In Vivo Activity (journal article)
Arico-Muendel, Christopher C. | Belanger, Bruce | Benjamin, Dennis | Blanchette, Heather S. | Caiazzo, Teresa M. | Centrella, Paolo A. | DeLorey, Jennifer | Doyle, Elisabeth G. | Gradhand, Ulrike | Griffin, Sarah T. | ... | White, Kerry F.
Drug Metabolism and Disposition, volume 41, issue 4, pages 814-826 (2013).
10.1124/dmd.112.048355
Cited by (10) | Cite | Source | Open Access
Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT) (journal article)
Deng, Hongfeng | O’Keefe, Heather | Davie, Christopher P. | Lind, Kenneth E. | Acharya, Raksha A. | Franklin, G. Joseph | Larkin, Jonathan | Matico, Rosalie | Neeb, Michael | Thompson, Monique M. | ... | Morgan, Barry A.
Journal of Medicinal Chemistry, volume 55, issue 16, pages 7061-7079 (2012).
10.1021/jm300449x
Cited by (129) | Cite | Source
Methods for identifying compounds of interest using encoded libraries (patent)
Morgan, Barry | Hale, Stephen | Arico-Muendel, Christopher C. | Clark, Matthew | Wagner, Richard | Israel, David I. | Gefter, Malcolm L. | Benjamin, Dennis | Hansen, Nils Jakob Vest | Kavarana, Malcolm J. | ... | Acharya, Raksha A.
Patent Number: 7989395 (2011)
Cited by (6) | Cite | Source
Methods for synthesis of encoded libraries (patent)
Morgan, Barry | Hale, Stephen | Arico-Muendel, Christopher C. | Clark, Matthew | Wagner, Richard | Israel, David I. | Gefter, Malcolm L. | Benjamin, Dennis | Hansen, Nils Jakob Vest | Kavarana, Malcolm J. | ... | Acharya, Raksha A.
Patent Number: 7972992 (2011)
Cited by (3) | Cite | Source
Methods for synthesis of encoded libraries (patent)
Morgan, Barry | Hale, Stephen | Arico-Muendel, Christopher C. | Clark, Matthew | Wagner, Richard | Israel, David I. | Gefter, Malcolm L. | Benjamin, Dennis | Hansen, Nils Jakob Vest | Kavarana, Malcolm J. | ... | Acharya, Raksha A.
Patent Number: 7972994 (2011)
Cited by (3) | Cite | Source
Methods for synthesis of encoded libraries (patent)
Morgan, Barry | Hale, Stephen | Arico-Muendel, Christopher C. | Clark, Matthew | Wagner, Richard | Israel, David I. | Gefter, Malcolm L. | Benjamin, Dennis | Hansen, Nils Jakob Vest | Kavarana, Malcolm J. | ... | Acharya, Raksha A.
Patent Number: 7935658 (2011)
Cited by (4) | Cite | Source
Carbamate Analogues of Fumagillin as Potent, Targeted Inhibitors of Methionine Aminopeptidase-2 (journal article)
Arico-Muendel, Christopher C. | Benjamin, Dennis R. | Caiazzo, Teresa M. | Centrella, Paolo A. | Contonio, Brooke D. | Cook, Charles M. | Doyle, Elisabeth G. | Hannig, Gerhard | Labenski, Matthew T. | Searle, Lily L. | ... | White, Kerry F.
Journal of Medicinal Chemistry, volume 52, issue 24, pages 8047-8056 (2009).
10.1021/jm901260k
Cited by (27) | Cite | Source