Jeffrey J. Crooke

ScholarGPS® ID: 81684290613047

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Medicinal Chemistry | Receptor Antagonist

Metrics Summary

Publication Count

Predicted Citations

663

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists (journal article) Shook, Brian C. \| Chakravarty, Devraj \| Barbay, J. Kent \| Wang, Aihua \| Leonard, Kristi \| Alford, Vernon \| Powell, Mark T. \| Rassnick, Stefanie \| Scannevin, Robert H. \| Carroll, Karen \| ... \| Jackson, Paul F. Bioorganic & Medicinal Chemistry Letters, volume 23, issue 9, pages 2688-2691 (2013). 10.1016/j.bmcl.2013.02.078 Cited by (19) \| Cite \| Source
Design and Characterization of Optimized Adenosine A2A /A1 Receptor Antagonists for the Treatment of Parkinson's Disease (journal article) Shook, Brian C. \| Rassnick, Stefanie \| Wallace, Nathaniel \| Crooke, Jeffrey \| Ault, Mark \| Chakravarty, Devraj \| Barbay, J. Kent \| Wang, Aihua \| Powell, Mark T. \| Leonard, Kristi \| ... \| Jackson, Paul F. Journal of Medicinal Chemistry, volume 55, issue 3, pages 1402-1417 (2012). 10.1021/jm201640m Cited by (50) \| Cite \| Source
Aminomethyl substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists (journal article) Shook, Brian C. \| Charavarty, Devraj \| Barbay, J. Kent \| Wang, Aihua \| Leonard, Kristi \| Alford, Vernon \| Powell, Mark \| Beauchamp, Derek A. \| Rassnick, Stefanie \| Scannevin, Robert \| ... \| Jackson, Paul F. MedChemComm, volume 2, issue 10, pages 950- (2011). 10.1039/c1md00082a Cited by (10) \| Cite \| Source
Optimization of arylindenopyrimidines as potent adenosine A2A/A1 antagonists (journal article) Shook, Brian C. \| Rassnick, Stefanie \| Chakravarty, Devraj \| Wallace, Nathaniel \| Ault, Mark \| Crooke, Jeffrey \| Barbay, J. Kent \| Wang, Aihua \| Leonard, Kristi \| Powell, Mark T. \| ... \| Jackson, Paul F. Bioorganic & Medicinal Chemistry Letters, volume 20, issue 9, pages 2868-2871 (2010). 10.1016/j.bmcl.2010.03.024 Cited by (12) \| Cite \| Source
Reduction of dominant or submissive behaviors as models for antimanic or antidepressant drug testing: Technical considerations (journal article) Malatynska, Ewa \| Pinhasov, Albert \| Crooke, Jeffrey J. \| Smith-Swintosky, Virginia L. \| Brenneman, Douglas E. Journal of Neuroscience Methods, volume 165, issue 2, pages 175-182 (2007). 10.1016/j.jneumeth.2007.05.035 Cited by (46) \| Cite \| Source
Assessing activity onset time and efficacy for clinically effective antidepressant and antimanic drugs in animal models based on dominant–submissive relationships (journal article) Malatynska, Ewa \| Pinhasov, Albert \| Creighton, Christopher J. \| Crooke, Jeffrey J. \| Reitz, Allen B. \| Brenneman, Douglas E. \| Lubomirski, Mariusz S. Neuroscience & Biobehavioral Reviews, volume 31, issue 6, pages 904-919 (2007). 10.1016/j.neubiorev.2007.05.004 Cited by (21) \| Cite \| Source
Diarylacetylene Piperidinyl Amides as Novel Anxiolytics. (journal article) Kordik, Cheryl P. \| Luo, Chi \| Gutherman, Maryann \| Vaidya, Anil H. \| Rosenthal, Daniel I. \| Crooke, Jeffrey J. \| McKenney, Sandra L. \| Plata‐Salaman, Carlos R. \| Reitz, Allen B. ChemInform, volume 37, issue 35 (2006). 10.1002/chin.200635138 Cite \| Source
Diarylacetylene piperidinyl amides as novel anxiolytics (journal article) Kordik, Cheryl P. \| Luo, Chi \| Gutherman, Maryann \| Vaidya, Anil H. \| Rosenthal, Daniel I. \| Crooke, Jeffrey J. \| McKenney, Sandra L. \| Plata-Salaman, Carlos R. \| Reitz, Allen B. Bioorganic & Medicinal Chemistry Letters, volume 16, issue 11, pages 3065-3067 (2006). 10.1016/j.bmcl.2006.02.027 Cited by (9) \| Cite \| Source
Levels of mRNA Coding for α-, β-, and γ-Synuclein in the Brains of Newborn, Juvenile, and Adult Rats (journal article) Malatynska, Ewa \| Pinhasov, Albert \| Crooke, Jeffrey \| Horowitz, Daniel \| Brenneman, Douglas E. \| Ilyin, Sergey E. Journal of Molecular Neuroscience, volume 29, issue 3, pages 269-278 (2006). 10.1385/JMN:29:3:269 Cited by (12) \| Cite \| Source
Reduction of Submissive Behavior Model for antidepressant drug activity testing: study using a video-tracking system (journal article) Pinhasov, Albert \| Crooke, Jeffrey \| Rosenthal, Daniel \| Brenneman, Douglas \| Malatynska, Ewa Behavioural Pharmacology, volume 16, issue 8, pages 657-664 (2005). 10.1097/00008877-200512000-00009 Cited by (43) \| Cite \| Source
The application of nuclear magnetic resonance-based metabonomics to the dominant–submissive rat behavioral model (journal article) Leo, Gregory C. \| Caldwell, Gary W. \| Crooke, Jeffrey \| Malatynska, Ewa \| Cotto, Carlos \| Hastings, Becki \| Scowcroft, Jaclyn \| Hall, Jeffrey \| Browne, Karina \| Hageman, William Analytical Biochemistry, volume 339, issue 1, pages 174-178 (2005). 10.1016/j.ab.2005.01.029 Cited by (17) \| Cite \| Source
Different levels of γ‐synuclein mRNA in the cerebral cortex of dominant, neutral and submissive rats selected in the competition test (journal article) Pinhasov, A. \| Ilyin, S. E. \| Crooke, J. \| Amato, F. A. \| Vaidya, A. H. \| Rosenthal, D. \| Brenneman, D. E. \| Malatynska, E. Genes, Brain and Behavior, volume 4, issue 1, pages 60-64 (2005). 10.1111/j.1601-183X.2004.00108.x Cited by (19) \| Cite \| Source \| Open Access
Oral buspirone causes a shift in the dose-response curve between the elevated-plus maze and Vogel conflict tests in long-Evans rats: Relation of brain levels of buspirone and 1-PP to anxiolytic action (journal article) Vaidya, A.H. \| Rosenthal, D.I. \| Lang, W., \| Crooke, J.J. \| Benjamin, D., \| Ilyin, S.E. \| Reitz, A.B. Methods and Findings in Experimental and Clinical Pharmacology , volume 27, issue 4, pages 245- (2005). 10.1358/mf.2005.27.4.893584 Cited by (13) \| Cite \| Source
2,3-Diaryl-5-anilino[1,2,4]thiadiazoles as melanocortin MC4 receptor agonists and their effects on feeding behavior in rats (journal article) Pan, Kevin \| Scott, Malcolm K \| Lee, Daniel H.S \| Fitzpatrick, Louis J \| Crooke, Jeffery J \| Rivero, Ralph A \| Rosenthal, Daniel I \| Vaidya, Anil H \| Zhao, Boyu \| Reitz, Allen B Bioorganic & Medicinal Chemistry, volume 11, issue 2, pages 185-192 (2003). 10.1016/S0968-0896(02)00428-5 Cited by (53) \| Cite \| Source
ChemInform Abstract: Pyrazolecarboxamide Human Neuropeptide Y5 Receptor Ligands with in vivo Antifeedant Activity. (journal article) Kordik, Cheryl P. \| Luo, Chi \| Zanoni, Brian C. \| Lovenberg, Timothy W. \| Wilson, Sandy J. \| Vaidya, Anil H. \| Crooke, Jeffrey J. \| Rosenthal, Daniel I. \| Reitz, Allen B. ChemInform, volume 32, issue 52 (2001). 10.1002/chin.200152115 Cite \| Source
Pyrazolecarboxamide human neuropeptide Y5 receptor ligands with in vivo antifeedant activity (journal article) Kordik, Cheryl P. \| Luo, Chi \| Zanoni, Brian C. \| Lovenberg, Timothy W. \| Wilson, Sandy J. \| Vaidya, Anil H. \| Crooke, Jeffrey J. \| Rosenthal, Daniel I. \| Reitz, Allen B. Bioorganic & Medicinal Chemistry Letters, volume 11, issue 17, pages 2287-2290 (2001). 10.1016/S0960-894X(01)00449-8 Cited by (19) \| Cite \| Source
2,3-Dihydro-dithiin and -dithiepine-1,1,4,4-tetroxides: small molecule non-peptide antagonists of the human galanin hGAL-1 receptor (journal article) Scott, Malcolm K \| Ross, Tina M \| Lee, Daniel H.S \| Wang, Hoau-Yan \| Shank, Richard P \| Wild, Kenneth D \| Davis, Coralie B \| Crooke, Jeffrey J \| Potocki, Alexander C \| Reitz, Allen B Bioorganic & Medicinal Chemistry, volume 8, issue 6, pages 1383-1391 (2000). 10.1016/S0968-0896(00)00062-6 Cited by (59) \| Cite \| Source
α-Substituted N -(Sulfonamido)alkyl-β-aminotetralins: Potent and Selective Neuropeptide Y Y5 Receptor Antagonists (journal article) Youngman, Mark A. \| McNally, James J. \| Lovenberg, Timothy W. \| Reitz, Allen B. \| Willard, Nicole M. \| Nepomuceno, Diane H. \| Wilson, Sandy J. \| Crooke, Jeffrey J. \| Rosenthal, Daniel \| Vaidya, Anil H. \| Dax, Scott L. Journal of Medicinal Chemistry, volume 43, issue 3, pages 346-350 (2000). 10.1021/jm990468g Cited by (41) \| Cite \| Source
alpha-Substituted N-(sulfonamido)alkyl-beta-aminotetralins: potent and selective neuropeptide Y Y5 receptor antagonists. (journal article) Youngman, M A \| McNally, J J \| Lovenberg, T W \| Reitz, A B \| Willard, N M \| Nepomuceno, D H \| Wilson, S J \| Crooke, J J \| Rosenthal, D \| Vaidya, A H \| Dax, S L Journal of medicinal chemistry, volume 43, issue 3 (2000). Cite