Alexandra L. Klinger

ScholarGPS® ID: 81498054363764

Affiliation
University of Pennsylvania, Philadelphia, United States
Affiliation History

Field
Pharmacy and Pharmaceutical Sciences
Discipline
Pharmacology and Toxicology
Top Specialties
Biophysics | Amyloid Beta | Hydroxyl Radical
Metrics Summary
Publication Count
27
Predicted Citations
652
Predicted h-index
15
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Quantitative Hydroxyl Radical Footprinting Study Reveals Structural Details of the Disorder-to-Order Transition in Amyloid-Beta (1-42) Oligomerization (journal article)
Kiselar, Janna | Nix, Andrew | Paravastu, Anant | Rosenberry, Terrone | Klinger, Alexandra
Biophysical Journal, volume 114, issue 3, pages 430a- (2018).
10.1016/j.bpj.2017.11.2385
Cite | Source
Sequence Specific Quantitative Hydroxyl Radical Footprinting Reveals Structural Details of Amyloid-ß (1-42) Peptide Oligomerization (journal article)
Kiselar, Janna | Nix, Andrew | Paravastu, Anant | Terrone, Rosenberry L. | Klinger, Alexandra L.
Biophysical Journal, volume 112, issue 3, pages 363a- (2017).
10.1016/j.bpj.2016.11.1970
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Amyloid-β(1-42)Oligomer Models Developed using Combined Solid State NMR and Sequence Specific Hydroxyl Radical Footprinting Data (journal article)
Klinger, Alexandra | Guo, Cong | Zhou, Huan-Xiang | Paravastu, Anant | Kiselar, Janna | Nix, Andrew J. | Rosenberry, Terrone L.
Biophysical Journal, volume 110, issue 3, pages 555a- (2016).
10.1016/j.bpj.2015.11.2966
Cite | Source | Open Access
Sequence Specific Radiolytic Footprinting Study of Monomer, Oligomeric and Fibrillar Amyloid Beta (1-42) (journal article)
Klinger, Alexandra L. | Kiselar, Janna | Paravastu, Anant | Rosenberry, Terrone
Biophysical Journal, volume 108, issue 2, pages 495a- (2015).
10.1016/j.bpj.2014.11.2708
Cite | Source | Open Access
A Synchrotron-Based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Prefibrillar Intermediates with Residue-Specific Resolution (journal article)
Klinger, Alexandra L. | Kiselar, Janna | Ilchenko, Serguei | Komatsu, Hiroaki | Chance, Mark R. | Axelsen, Paul H.
Biochemistry, volume 53, issue 49, pages 7724-7734 (2014).
10.1021/bi5010409
Cited by (24) | Cite | Source | Open Access
Pefluorocarbon inhibition of bubble induced Ca2+ transients in an in vitro model of vascular gas embolism (journal article)
Klinger, Alexandra L | Kandel, Judith | Pichette, Benjamin | Eckmann, David M
Experimental Biology and Medicine, volume 239, issue 1, pages 116-122 (2014).
10.1177/1535370213506434
Cited by (4) | Cite | Source | Open Access
Oxidative Footprinting of Fibrillar and Prefibrillar Oligomeric Forms of Amyloid Beta (journal article)
Klinger, Alexandra L. | Kiselar, Janna | Chance, Mark | Axelsen, Paul H.
Biophysical Journal, volume 104, issue 2, pages 399a- (2013).
10.1016/j.bpj.2012.11.2225
Cited by (1) | Cite | Source | Open Access
Oxidative Footprinting of Fibrillar and Prefibrillar Oligomer Forms of Amyloid Beta (journal article)
Klinger, Alexandra L. | Axelsen, Paul H.
Biophysical Journal, volume 102, issue 3, pages 242a- (2012).
10.1016/j.bpj.2011.11.1333
Cite | Source | Open Access
Air bubble contact with endothelial cells in vitro induces calcium influx and IP3-dependent release of calcium stores (journal article)
Sobolewski, Peter | Kandel, Judith | Klinger, Alexandra L. | Eckmann, David M.
American Journal of Physiology-Cell Physiology, volume 301, issue 3, pages C679-C686 (2011).
10.1152/ajpcell.00046.2011
Cited by (34) | Cite | Source | Open Access
Understanding the Mechanotransductional Basis of Intravascular Bubble Injury (journal article)
Klinger, Alexandra L. | Pichette, Benjamin | Eckmann, David M.
Biophysical Journal, volume 100, issue 3, pages 280a- (2011).
10.1016/j.bpj.2010.12.1736
Cite | Source | Open Access
Mechanotransductional basis of endothelial cell response to intravascular bubbles (journal article)
Klinger, Alexandra L. | Pichette, Benjamin | Sobolewski, Peter | Eckmann, David M.
Integrative Biology, volume 3, issue 10, pages 1033- (2011).
10.1039/c1ib00017a
Cited by (25) | Cite | Source | Open Access
Cellular Potts Modeling of Matrix-Dependent Endothelial Cell Networking (journal article)
Klinger, Alexandra | Lucia, Andrew | Sabin, Jenny | Jones, Peter Lloyd
Biophysical Journal, volume 96, issue 3, pages 628a- (2009).
10.1016/j.bpj.2008.12.3318
Cite | Source | Open Access
Structural determination of estrogen-related receptor γ in the presence of phenol derivative compounds (journal article)
Abad, Marta C. | Askari, Hossein | O’Neill, John | Klinger, Alexandra L. | Milligan, Cynthia | Lewandowski, Frank | Springer, Barry | Spurlino, John | Rentzeperis, Dionisios
The Journal of Steroid Biochemistry and Molecular Biology, volume 108, issue 1-2, pages 44-54 (2008).
10.1016/j.jsbmb.2007.06.006
Cited by (54) | Cite | Source
A MurF Inhibitor That Disrupts Cell Wall Biosynthesis in Escherichia coli (journal article)
Baum, Ellen Z. | Crespo-Carbone, Steven M. | Klinger, Alexandra | Foleno, Barbara D. | Turchi, Ignatius | Macielag, Mark | Bush, Karen
Antimicrobial Agents and Chemotherapy, volume 51, issue 12, pages 4420-4426 (2007).
10.1128/AAC.00845-07
Cited by (37) | Cite | Source | Open Access
Thermal stability landscape for Klenow DNA polymerase as a function of pH and salt concentration (journal article)
Richard, Allison J. | Liu, Chin-Chi | Klinger, Alexandra L. | Todd, Matthew J. | Mezzasalma, Tara M. | LiCata, Vince J.
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, volume 1764, issue 10, pages 1546-1552 (2006).
10.1016/j.bbapap.2006.08.011
Cited by (27) | Cite | Source
Inhibition of Carbonic Anhydrase-II by Sulfamate and Sulfamide Groups:  An Investigation Involving Direct Thermodynamic Binding Measurements (journal article)
Klinger, Alexandra L. | McComsey, David F. | Smith-Swintosky, Virginia | Shank, Richard P. | Maryanoff, Bruce E.
Journal of Medicinal Chemistry, volume 49, issue 12, pages 3496-3500 (2006).
10.1021/jm058279n
Cited by (45) | Cite | Source
Asymmetric Distribution of Cooperativity in the Binding Cascade of Normal Human Hemoglobin. 1. Cooperative and Noncooperative Oxygen Binding in Zn-Substituted Hemoglobin (journal article)
Holt, Jo M. | Klinger, Alexandra L. | Yarian, Connie S. | Keelara, Varsha | Ackers, Gary K.
Biochemistry, volume 44, issue 36, pages 11925-11938 (2005).
10.1021/bi050709o
Cited by (8) | Cite | Source
Confirmation of a unique intra-dimer cooperativity in the human hemoglobin ?1?1half-oxygenated intermediate supports the symmetry rule model of allosteric regulation (journal article)
Ackers, Gary K. | Holt, Jo M. | Huang, Yingwen | Grinkova, Yelena | Klinger, Alexandra L. | Denisov, Ilia
Proteins: Structure, Function, and Genetics, volume 41, issue S4, pages 23-43 (2000).
10.1002/1097-0134(2000)41:4+<23::AID-PROT30>3.0.CO;2-D
Cited by (32) | Cite | Source
Confirmation of a unique intra-dimer cooperativity in the human hemoglobin alpha(1)beta(1)half-oxygenated intermediate supports the symmetry rule model of allosteric regulation. (journal article)
Ackers, G K | Holt, J M | Huang, Y | Grinkova, Y | Klinger, A L | Denisov, I
Proteins, volume Suppl 4 (2000).
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Thermodynamic Studies on the Equilibrium Properties of a Series of Recombinant βW37 Hemoglobin Mutants† (journal article)
Kiger, Laurent | Klinger, Alexandra L. | Kwiatkowski, Laura D. | De Young, Alice | Doyle, Michael L. | Holt, Jo M. | Noble, Robert W. | Ackers, Gary K.
Biochemistry, volume 37, issue 13, pages 4336-4345 (1998).
10.1021/bi970868a
Cited by (17) | Cite | Source