Anthony C. Arvanites

ScholarGPS® ID: 80742955193854

Affiliation

Northwestern University, Evanston, United States

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Amyotrophic Lateral Sclerosis | Neuron | Medicinal Chemistry

Metrics Summary

Publication Count

Predicted Citations

2,262

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer (journal article) Cronin, Shane J. F. \| Rao, Shuan \| Tejada, Miguel A. \| Turnes, Bruna Lenfers \| Licht-Mayer, Simon \| Omura, Takao \| Brenneis, Christian \| Jacobs, Emily \| Barrett, Lee \| Latremoliere, Alban \| ... \| Woolf, Clifford J. Science Translational Medicine, volume 14, issue 660 (2022). 10.1126/scitranslmed.abj1531 Cited by (14) \| Cite \| Source
Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells (journal article) Sadegh, Cameron \| Ebina, Wataru \| Arvanites, Anthony C. \| Davidow, Lance S. \| Rubin, Lee L. \| Macklis, Jeffrey D. PLOS ONE, volume 16, issue 9, pages e0254113- (2021). 10.1371/journal.pone.0254113 Cited by (2) \| Cite \| Source
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons (journal article) Cheng, Yung-Chih \| Snavely, Andrew \| Barrett, Lee B. \| Zhang, Xuefei \| Herman, Crystal \| Frost, Devlin J. \| Riva, Priscilla \| Tochitsky, Ivan \| Kawaguchi, Riki \| Singh, Bhagat \| ... \| Woolf, Clifford J. Cell Reports, volume 36, issue 10, pages 109666- (2021). 10.1016/j.celrep.2021.109666 Cited by (15) \| Cite \| Source
Treatment of amyotrophic lateral sclerosis (patent) Kirsch, Donald R. \| Benmohamed, Radhia \| Arvanites, Anthony C. \| Morimoto, Richard I. \| Chen, Tian \| Silverman, Richard B. Patent Number: 10167263 (2019) Cite \| Source
Nucleophilic aromatic substitution in chlorinated aromatic systems with a glutathione thiolate model (journal article) Boerth, Donald W. \| Arvanites, Anthony C. Journal of Physical Organic Chemistry, volume 30, issue 7, pages e3640- (2017). 10.1002/poc.3640 Cited by (2) \| Cite \| Source
Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis (patent) Kirsch, Donald R. \| Benmohamed, Radhia \| Arvanites, Anthony C. \| Morimoto, Richard I. \| Zhang, Wei \| Silverman, Richard B. Patent Number: 9593069 (2017) Cite \| Source
Pyrimidine-2,4,6-triones for use in the treatment of amyotrophic lateral sclerosis (patent) Kirsch, Donald R. \| Benmohamed, Radhia \| Arvanites, Anthony C. \| Morimoto, Richard I. \| Xia, Guoyao \| Silverman, Richard B. Patent Number: 9499494 (2016) Cite \| Source
Repurposing cAMP-Modulating Medications to Promote β-Cell Replication (journal article) Zhao, Zhenshan \| Low, Yen S. \| Armstrong, Neali A. \| Ryu, Jennifer Hyoje \| Sun, Sara A. \| Arvanites, Anthony C. \| Hollister-Lock, Jennifer \| Shah, Nigam H. \| Weir, Gordon C. \| Annes, Justin P. Molecular Endocrinology, volume 28, issue 10, pages 1682-1697 (2014). 10.1210/me.2014-1120 Cited by (25) \| Cite \| Source \| Open Access
Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway (journal article) Blum, Barak \| Roose, Adam N \| Barrandon, Ornella \| Maehr, René \| Arvanites, Anthony C \| Davidow, Lance S \| Davis, Jeffrey C \| Peterson, Quinn P \| Rubin, Lee L \| Melton, Douglas A eLife, volume 3 (2014). 10.7554/eLife.02809 Cited by (107) \| Cite \| Source \| Open Access
Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis (patent) Kirsch, Donald R. \| Benmohamed, Radhia \| Arvanites, Anthony C. \| Morimoto, Richard I. \| Zhang, Wei \| Silverman, Richard B. Patent Number: 8722939 (2014) Cite \| Source
A Small Molecule Screen in Stem-Cell-Derived Motor Neurons Identifies a Kinase Inhibitor as a Candidate Therapeutic for ALS (journal article) Yang, Yin M. \| Gupta, Shailesh K. \| Kim, Kevin J. \| Powers, Berit E. \| Cerqueira, Antonio \| Wainger, Brian J. \| Ngo, Hien D. \| Rosowski, Kathryn A. \| Schein, Pamela A. \| Ackeifi, Courtney A. \| ... \| Rubin, Lee L. Cell Stem Cell, volume 12, issue 6, pages 713-726 (2013). 10.1016/j.stem.2013.04.003 Cited by (269) \| Cite \| Source \| Open Access
Glucocorticoid Compounds Modify Smoothened Localization and Hedgehog Pathway Activity (journal article) Wang, Yu \| Davidow, Lance \| Arvanites, Anthony C. \| Blanchard, Joel \| Lam, Kelvin \| Xu, Ke \| Oza, Vatsal \| Yoo, Jin Woo \| Ng, Jessica M.Y. \| Curran, Tom \| ... \| McMahon, Andrew P. Chemistry & Biology, volume 19, issue 8, pages 972-982 (2012). 10.1016/j.chembiol.2012.06.012 Cited by (57) \| Cite \| Source \| Open Access
Selective Identification of Hedgehog Pathway Antagonists By Direct Analysis of Smoothened Ciliary Translocation (journal article) Wang, Yu \| Arvanites, Anthony C. \| Davidow, Lance \| Blanchard, Joel \| Lam, Kelvin \| Yoo, Jin Woo \| Coy, Shannon \| Rubin, Lee L. \| McMahon, Andrew P. ACS Chemical Biology, volume 7, issue 6, pages 1040-1048 (2012). 10.1021/cb300028a Cited by (39) \| Cite \| Source \| Open Access
Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication (journal article) Annes, Justin P. \| Ryu, Jennifer Hyoje \| Lam, Kelvin \| Carolan, Peter J. \| Utz, Katrina \| Hollister-Lock, Jennifer \| Arvanites, Anthony C. \| Rubin, Lee L. \| Weir, Gordon \| Melton, Douglas A. Proceedings of the National Academy of Sciences, volume 109, issue 10, pages 3915-3920 (2012). 10.1073/pnas.1201149109 Cited by (121) \| Cite \| Source \| Open Access
Cyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells (journal article) Zhang, Wei \| Benmohamed, Radhia \| Arvanites, Anthony C. \| Morimoto, Richard I. \| Ferrante, Robert J. \| Kirsch, Donald R. \| Silverman, Richard B. Bioorganic & Medicinal Chemistry, volume 20, issue 2, pages 1029-1045 (2012). 10.1016/j.bmc.2011.11.039 Cited by (22) \| Cite \| Source \| Open Access
A screen for regulators of survival of motor neuron protein levels (journal article) Makhortova, Nina R \| Hayhurst, Monica \| Cerqueira, Antonio \| Sinor-Anderson, Amy D \| Zhao, Wen-Ning \| Heiser, Patrick W \| Arvanites, Anthony C \| Davidow, Lance S \| Waldon, Zachary O \| Steen, Judith A \| ... \| Rubin, Lee L Nature Chemical Biology, volume 7, issue 8, pages 544-552 (2011). 10.1038/nchembio.595 Cited by (82) \| Cite \| Source \| Open Access
Pyrimidine-2,4,6-trione Derivatives and Their Inhibition of Mutant SOD1-Dependent Protein Aggregation. Toward a Treatment for Amyotrophic Lateral Sclerosis (journal article) Xia, Guoyao \| Benmohamed, Radhia \| Kim, Jinho \| Arvanites, Anthony C. \| Morimoto, Richard I. \| Ferrante, Robert J. \| Kirsch, Donald R. \| Silverman, Richard B. Journal of Medicinal Chemistry, volume 54, issue 7, pages 2409-2421 (2011). 10.1021/jm101549k Cited by (44) \| Cite \| Source \| Open Access
Identification of compounds protective against G93A-SOD1 toxicity for the treatment of amyotrophic lateral sclerosis (journal article) Benmohamed, Radhia \| Arvanites, Anthony C. \| Kim, Jinho \| Ferrante, Robert J. \| Silverman, Richard B. \| Morimoto, Richard I. \| Kirsch, Donald R. Amyotrophic Lateral Sclerosis, volume 12, issue 2, pages 87-96 (2011). 10.3109/17482968.2010.522586 Cited by (35) \| Cite \| Source
Arylsulfanyl pyrazolones block mutant SOD1-G93A aggregation. Potential application for the treatment of amyotrophic lateral sclerosis (journal article) Chen, Tian \| Benmohamed, Radhia \| Arvanites, Anthony C. \| Ranaivo, Hantamalala Ralay \| Morimoto, Richard I. \| Ferrante, Robert J. \| Watterson, D. Martin \| Kirsch, Donald R. \| Silverman, Richard B. Bioorganic & Medicinal Chemistry, volume 19, issue 1, pages 613-622 (2011). 10.1016/j.bmc.2010.10.052 Cited by (22) \| Cite \| Source \| Open Access
Virtual drug discovery: beyond computational chemistry? (journal article) Gilardoni, Francois \| Arvanites, Anthony C Expert Opinion on Drug Discovery, volume 5, issue 2, pages 113-115 (2010). 10.1517/17460440903369821 Cited by (1) \| Cite \| Source