Andrei Khokhlatchev

ScholarGPS® ID: 80633362228982

Affiliation

University of Virginia, Charlottesville, United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacology and Toxicology

Top Specialties

Neoplasm | Tumor Suppressor | Phosphorylation

Metrics Summary

Publication Count

Predicted Citations

4,063

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia (journal article) Khokhlatchev, Andrei V. \| Sharma, Arati \| Deering, Tye G. \| Shaw, Jeremy J. P. \| Costa‐Pinheiro, Pedro \| Golla, Upendarrao \| Annageldiyev, Charyguly \| Cabot, Myles C. \| Conaway, Mark R. \| Tan, Su‐Fern \| ... \| Kester, Mark The FASEB Journal, volume 36, issue 10 (2022). 10.1096/fj.202200765R Cited by (7) \| Cite \| Source
Minicells from Highly Genome Reduced Escherichia coli : Cytoplasmic and Surface Expression of Recombinant Proteins and Incorporation in the Minicells (journal article) Yu, Hanna \| Khokhlatchev, Andrei V. \| Chew, Claude \| Illendula, Anuradha \| Conaway, Mark \| Dryden, Kelly \| Maeda, Denicar Lina Nascimento Fabris \| Rajasekaran, Vignesh \| Kester, Mark \| Zeichner, Steven L. ACS Synthetic Biology, volume 10, issue 10, pages 2465-2477 (2021). 10.1021/acssynbio.1c00375 Cited by (2) \| Cite \| Source
Lysosomal Degradation of CD44 Mediates Ceramide Nanoliposome-induced Anoikis and Diminished Extravasation in Metastatic Carcinoma Cells (journal article) Haakenson, Jeremy K. \| Khokhlatchev, Andrei V. \| Choi, Younhee J. \| Linton, Samuel S. \| Zhang, Pu \| Zaki, Peter M. \| Fu, Changliang \| Cooper, Timothy K. \| Manni, Andrea \| Zhu, Junjia \| ... \| Kester, Mark Journal of Biological Chemistry, volume 290, issue 13, pages 8632-8643 (2015). 10.1074/jbc.M114.609677 Cited by (15) \| Cite \| Source \| Open Access
Growth and Tumor Suppressor NORE1A Is a Regulatory Node between Ras Signaling and Microtubule Nucleation (journal article) Bee, Christine \| Moshnikova, Anna \| Mellor, Christopher D. \| Molloy, Justin E. \| Koryakina, Yulia \| Stieglitz, Benjamin \| Khokhlatchev, Andrei \| Herrmann, Christian Journal of Biological Chemistry, volume 285, issue 21, pages 16258-16266 (2010). 10.1074/jbc.M109.081562 Cited by (17) \| Cite \| Source \| Open Access
The Growth and Tumor Suppressors NORE1A and RASSF1A Are Targets for Calpain-Mediated Proteolysis (journal article) Kuznetsov, Sergey \| Khokhlatchev, Andrei V. PLoS ONE, volume 3, issue 12, pages e3997- (2008). 10.1371/journal.pone.0003997 Cited by (9) \| Cite \| Source \| Open Access
Interaction of the growth and tumour suppressor NORE1A with microtubules is not required for its growth-suppressive function (journal article) Moshnikova, Anna \| Kuznetsov, Sergey \| Khokhlatchev, Andrei V BMC Research Notes, volume 1, issue 1 (2008). 10.1186/1756-0500-1-13 Cited by (9) \| Cite \| Source \| Open Access
Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II (journal article) Stieglitz, Benjamin \| Bee, Christine \| Schwarz, Daniel \| Yildiz, Özkan \| Moshnikova, Anna \| Khokhlatchev, Andrei \| Herrmann, Christian The EMBO Journal, volume 27, issue 14, pages 1995-2005 (2008). 10.1038/emboj.2008.125 Cited by (91) \| Cite \| Source \| Open Access
Characterization of Mitogen-Activated Protein Kinase (MAPK) Dimers (journal article) Wilsbacher, Julie L. \| Juang, Yu-Chi \| Khokhlatchev, Andrei V. \| Gallagher, Ewen \| Binns, Derk \| Goldsmith, Elizabeth J. \| Cobb, Melanie H. Biochemistry, volume 45, issue 44, pages 13175-13182 (2006). 10.1021/bi061041w Cited by (29) \| Cite \| Source
The Growth and Tumor Suppressor NORE1A Is a Cytoskeletal Protein That Suppresses Growth by Inhibition of the ERK Pathway (journal article) Moshnikova, Anna \| Frye, Judson \| Shay, Jerry W. \| Minna, John D. \| Khokhlatchev, Andrei V. Journal of Biological Chemistry, volume 281, issue 12, pages 8143-8152 (2006). 10.1074/jbc.M511837200 Cited by (41) \| Cite \| Source \| Open Access
The Scaffold Protein CNK1 Interacts with the Tumor Suppressor RASSF1A and Augments RASSF1A-induced Cell Death (journal article) Rabizadeh, Shahrooz \| Xavier, Ramnik J. \| Ishiguro, Kazuhiro \| Bernabeortiz, Juliocesar \| Lopez-Ilasaca, Marco \| Khokhlatchev, Andrei \| Mollahan, Pamela \| Pfeifer, Gerd P. \| Avruch, Joseph \| Seed, Brian Journal of Biological Chemistry, volume 279, issue 28, pages 29247-29254 (2004). 10.1074/jbc.M401699200 Cited by (78) \| Cite \| Source \| Open Access
RASSF1A may serve as novel tumor suppressor gene in gastrointestinal malignancies regulating apoptosis (journal article) Ortiz, Juliocesar Bemabe \| Rabizadeh, Shahrooz \| Ishiguro, Kazuhiro \| Lopez-Ilasaca, Marco \| Khokhlatchev, Andrei \| Avruch, Joseph \| Seed, Brian \| Xavier, Ramnik Gastroenterology, volume 124, issue 4, pages A288- (2003). 10.1016/S0016-5085(03)81449-X Cite \| Source
Death-associated Protein 4 Binds MST1 and Augments MST1-induced Apoptosis (journal article) Lin, Yenshou \| Khokhlatchev, Andrei \| Figeys, Daniel \| Avruch, Joseph Journal of Biological Chemistry, volume 277, issue 50, pages 47991-48001 (2002). 10.1074/jbc.M202630200 Cited by (73) \| Cite \| Source \| Open Access
Erratum: The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1 (journal article) Ortiz-Vega, Sara \| Khokhlatchev, Andrei \| Nedwidek, Maria \| Zhang, Xian-feng \| Dammann, Reinhard \| Pfeifer, Gerd P \| Avruch, Joseph Oncogene, volume 21, issue 12, pages 1943-1943 (2002). 10.1038/sj.onc.1205378 Cited by (1) \| Cite \| Source \| Open Access
The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1 (journal article) Ortiz-Vega, Sara \| Khokhlatchev, Andrei \| Nedwidek, Maria \| Zhang, Xian-feng \| Dammann, Reinhard \| Pfeifer, Gerd P \| Avruch, Joseph Oncogene, volume 21, issue 9, pages 1381-1390 (2002). 10.1038/sj.onc.1205192 Cited by (180) \| Cite \| Source \| Open Access
Identification of a Novel Ras-Regulated Proapoptotic Pathway (journal article) Khokhlatchev, Andrei \| Rabizadeh, Shahrooz \| Xavier, Ramnik \| Nedwidek, Maria \| Chen, Tao \| Zhang, Xian-feng \| Seed, Brian \| Avruch, Joseph Current Biology, volume 12, issue 4, pages 253-265 (2002). 10.1016/S0960-9822(02)00683-8 Cited by (315) \| Cite \| Source \| Open Access
Differential Effects of PAK1-activating Mutations Reveal Activity-dependent and -independent Effects on Cytoskeletal Regulation (journal article) Frost, Jeffrey A. \| Khokhlatchev, Andrei \| Stippec, Steve \| White, Michael A. \| Cobb, Melanie H. Journal of Biological Chemistry, volume 273, issue 43, pages 28191-28198 (1998). 10.1074/jbc.273.43.28191 Cited by (180) \| Cite \| Source \| Open Access
Phosphorylation of the MAP Kinase ERK2 Promotes Its Homodimerization and Nuclear Translocation (journal article) Khokhlatchev, Andrei V \| Canagarajah, Bertram \| Wilsbacher, Julie \| Robinson, Megan \| Atkinson, Mark \| Goldsmith, Elizabeth \| Cobb, Melanie H Cell, volume 93, issue 4, pages 605-615 (1998). 10.1016/S0092-8674(00)81189-7 Cited by (586) \| Cite \| Source \| Open Access
Activation Mechanism of the MAP Kinase ERK2 by Dual Phosphorylation (journal article) Canagarajah, Bertram J. \| Khokhlatchev, Andrei \| Cobb, Melanie H. \| Goldsmith, Elizabeth J. Cell, volume 90, issue 5, pages 859-869 (1997). 10.1016/S0092-8674(00)80351-7 Cited by (642) \| Cite \| Source \| Open Access
Reconstitution of Mitogen-activated Protein Kinase Phosphorylation Cascades in Bacteria (journal article) Khokhlatchev, Andrei \| Xu, Shuichan \| English, Jessie \| Wu, Peiqun \| Schaefer, Erik \| Cobb, Melanie H. Journal of Biological Chemistry, volume 272, issue 17, pages 11057-11062 (1997). 10.1074/jbc.272.17.11057 Cited by (180) \| Cite \| Source \| Open Access
Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria. Efficient synthesis of active protein kinases. (journal article) Khokhlatchev, A \| Xu, S \| English, J \| Wu, P \| Schaefer, E \| Cobb, M H The Journal of biological chemistry, volume 272, issue 17 (1997). Cite