Richard T. Eastman

ScholarGPS® ID: 80277369432151

Affiliation

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, United States

Affiliation History

Field

Life Sciences

Discipline

Microbiology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

4,719

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Establishment of human post-vaccination SARS-CoV-2 standard reference sera (journal article) Xiang, Jinhua \| Katz, Louis \| Winokur, Patricia L. \| Chaudhary, Ashok \| Digmann, Barbara \| Bradford, Rebecca \| Rashid, Sujatha \| Ghosh, Sudakshina \| Robertson, Angela \| Menetski, Joseph \| ... \| Stapleton, Jack T. Journal of Immunological Methods, volume 530 (2024). 10.1016/j.jim.2024.113698 Cited by (1) \| Cite \| Source
Small molecule antiviral compound collection (SMACC): A comprehensive, highly curated database to support the discovery of broad-spectrum antiviral drug molecules (journal article) Martin, Holli-Joi \| Melo-Filho, Cleber C. \| Korn, Daniel \| Eastman, Richard T. \| Rai, Ganesha \| Simeonov, Anton \| Zakharov, Alexey V. \| Muratov, Eugene \| Tropsha, Alexander Antiviral Research, volume 217 (2023). 10.1016/j.antiviral.2023.105620 Cite \| Source
Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products (journal article) Yasgar, Adam \| Bougie, Danielle \| Eastman, Richard T. \| Huang, Ruili \| Itkin, Misha \| Kouznetsova, Jennifer \| Lynch, Caitlin \| McKnight, Crystal \| Miller, Mitch \| Ngan, Deborah K. \| ... \| Simeonov, Anton ACS Pharmacology & Translational Science, volume 6, issue 5, pages 683-701 (2023). 10.1021/acsptsci.2c00194 Cite \| Source
Novel Transmission-Blocking Antimalarials Identified by High-Throughput Screening of Plasmodium berghei Ookluc (journal article) Calit, Juliana \| Araújo, Jessica E. \| Deng, Bingbing \| Miura, Kazutoyo \| Gaitán, Xiomara A. \| Araújo, Maisa da Silva \| Medeiros, Jansen F. \| Long, Carole A. \| Simeonov, Anton \| Eastman, Richard T. \| Bargieri, Daniel Y. Antimicrobial Agents and Chemotherapy, volume 67, issue 4 (2023). 10.1128/aac.01465-22 Cited by (4) \| Cite \| Source
A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses (journal article) Singh, Brajesh K. \| Zhang, Cui \| Wu, Jian \| Peng, Yu-Chih \| He, Xiao \| Tumas, Keyla C. \| Sá, Juliana M. \| Lane, Kristin D. \| Eastman, Richard T. \| Narum, David L. \| ... \| Su, Xin-zhuan Antimicrobial Agents and Chemotherapy, volume 67, issue 2 (2023). 10.1128/aac.00821-22 Cited by (1) \| Cite \| Source
Allosteric Binders of ACE2 Are Promising Anti-SARS-CoV-2 Agents (journal article) Hochuli, Joshua E. \| Jain, Sankalp \| Melo-Filho, Cleber \| Sessions, Zoe L. \| Bobrowski, Tesia \| Choe, Jun \| Zheng, Johnny \| Eastman, Richard \| Talley, Daniel C. \| Rai, Ganesha \| ... \| Zakharov, Alexey V. ACS Pharmacology & Translational Science, volume 5, issue 7, pages 468-478 (2022). 10.1021/acsptsci.2c00049 Cited by (5) \| Cite \| Source
A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model (journal article) Dorjsuren, Dorjbal \| Eastman, Richard T. \| Song, Min Jae \| Yasgar, Adam \| Chen, Yuchi \| Bharti, Kapil \| Zakharov, Alexey V. \| Jadhav, Ajit \| Ferrer, Marc \| Shi, Pei-Yong \| Simeonov, Anton PLOS ONE, volume 17, issue 1, pages e0261821- (2022). 10.1371/journal.pone.0261821 Cited by (6) \| Cite \| Source
Deep learning identifies synergistic drug combinations for treating COVID-19 (journal article) Jin, Wengong \| Stokes, Jonathan M. \| Eastman, Richard T. \| Itkin, Zina \| Zakharov, Alexey V. \| Collins, James J. \| Jaakkola, Tommi S. \| Barzilay, Regina Proceedings of the National Academy of Sciences, volume 118, issue 39 (2021). 10.1073/pnas.2105070118 Cited by (91) \| Cite \| Source
Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection (journal article) Shamim, Khalida \| Xu, Miao \| Hu, Xin \| Lee, Emily M \| Lu, Xiao \| Huang, Ruili \| Shah, Pranav \| Xu, Xin \| Chen, Catherine Z. \| Shen, Min \| ... \| Huang, Wenwei Bioorganic & Medicinal Chemistry Letters, volume 40 (2021). 10.1016/j.bmcl.2021.127906 Cited by (14) \| Cite \| Source
Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 (journal article) Bobrowski, Tesia \| Chen, Lu \| Eastman, Richard T. \| Itkin, Zina \| Shinn, Paul \| Chen, Catherine Z. \| Guo, Hui \| Zheng, Wei \| Michael, Sam \| Simeonov, Anton \| ... \| Muratov, Eugene N. Molecular Therapy, volume 29, issue 2, pages 873-885 (2021). 10.1016/j.ymthe.2020.12.016 Cited by (67) \| Cite \| Source
Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2 (journal article) Chen, Catherine Z. \| Shinn, Paul \| Itkin, Zina \| Eastman, Richard T. \| Bostwick, Robert \| Rasmussen, Lynn \| Huang, Ruili \| Shen, Min \| Hu, Xin \| Wilson, Kelli M. \| ... \| Zheng, Wei Frontiers in Pharmacology, volume 11 (2021). 10.3389/fphar.2020.592737 Cited by (52) \| Cite \| Source
Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Plasmodium falciparum Genotype (journal article) Ansbro, Megan R. \| Itkin, Zina \| Chen, Lu \| Zahoranszky-Kohalmi, Gergely \| Amaratunga, Chanaki \| Miotto, Olivo \| Peryea, Tyler \| Hobbs, Charlotte V. \| Suon, Seila \| Sá, Juliana M. \| ... \| Eastman, Richard T. ACS Pharmacology & Translational Science, volume 3, issue 6, pages 1144-1157 (2020). 10.1021/acsptsci.0c00110 Cited by (6) \| Cite \| Source
Targeting ACE2–RBD Interaction as a Platform for COVID-19 Therapeutics: Development and Drug-Repurposing Screen of an AlphaLISA Proximity Assay (journal article) Hanson, Quinlin M. \| Wilson, Kelli M. \| Shen, Min \| Itkin, Zina \| Eastman, Richard T. \| Shinn, Paul \| Hall, Matthew D. ACS Pharmacology & Translational Science, volume 3, issue 6, pages 1352-1360 (2020). 10.1021/acsptsci.0c00161 Cited by (53) \| Cite \| Source
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors (journal article) Abrams, Rachel P. M. \| Yasgar, Adam \| Teramoto, Tadahisa \| Lee, Myoung-Hwa \| Dorjsuren, Dorjbal \| Eastman, Richard T. \| Malik, Nasir \| Zakharov, Alexey V. \| Li, Wenxue \| Bachani, Muzna \| ... \| Nath, Avindra Proceedings of the National Academy of Sciences, volume 117, issue 49, pages 31365-31375 (2020). 10.1073/pnas.2005463117 Cited by (29) \| Cite \| Source
Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 (journal article) Eastman, Richard T. \| Roth, Jacob S. \| Brimacombe, Kyle R. \| Simeonov, Anton \| Shen, Min \| Patnaik, Samarjit \| Hall, Matthew D. ACS Central Science, volume 6, issue 5, pages 672-683 (2020). 10.1021/acscentsci.0c00489 Cited by (633) \| Cite \| Source
Discovery of Synergistic and Antagonistic Drug Combinations Against SARS-CoV-2 <i>In Vitro</i> (journal article) Bobrowski, Tesia \| Chen, Lu \| Eastman, Richard T. \| Itkin, Zina \| Shinn, Paul \| Chen, Catherine Z. \| Guo, Hui \| Zheng, Wei \| Michael, Sam \| Simeonov, Anton \| ... \| Muratov, Eugene SSRN Electronic Journal (2020). 10.2139/ssrn.3666250 Cited by (9) \| Cite \| Source
A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria (journal article) KalantarMotamedi, Yasaman \| Eastman, Richard T. \| Guha, Rajarshi \| Bender, Andreas Malaria Journal, volume 17, issue 1 (2018). 10.1186/s12936-018-2294-5 Cited by (14) \| Cite \| Source \| Open Access
A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation (journal article) Breglio, Kimberly F. \| Amato, Roberto \| Eastman, Richard \| Lim, Pharath \| Sa, Juliana M. \| Guha, Rajarshi \| Ganesan, Sundar \| Dorward, David W. \| Klumpp-Thomas, Carleen \| McKnight, Crystal \| ... \| Simon, Anna Katharina Malaria Journal, volume 17, issue 1 (2018). 10.1186/s12936-018-2532-x Cited by (28) \| Cite \| Source
Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Compounds (journal article) Calit, Juliana \| Dobrescu, Irina \| Gaitán, Xiomara A. \| Borges, Miriam H. \| Ramos, Marisé S. \| Eastman, Richard T. \| Bargieri, Daniel Y. Antimicrobial Agents and Chemotherapy, volume 62, issue 11 (2018). 10.1128/AAC.01053-18 Cited by (19) \| Cite \| Source
Using Machine Learning to Predict Synergistic Antimalarial Compound Combinations With Novel Structures (journal article) Mason, Daniel J. \| Eastman, Richard T. \| Lewis, Richard P. I. \| Stott, Ian P. \| Guha, Rajarshi \| Bender, Andreas Frontiers in Pharmacology, volume 9 (2018). 10.3389/fphar.2018.01096 Cited by (29) \| Cite \| Source