Michael Reuman

ScholarGPS® ID: 79307343638502

Affiliation
Janssen Pharmaceutica
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Medicinal Chemistry | Chemical Synthesis | Receptor Modulator | Vascular Endothelial Growth Factor
Metrics Summary
Publication Count
36
Predicted Citations
1,510
Predicted h-index
16
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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FUSED CYCLOPENTYL ANTAGONISTS OF CCR2 (patent)
Winters, Michael P. | Branum, Shawn | Fawzy, Nagy | Kang, Fu-An | Reuman, Michael | Russell, Ronald K. | Sui, Zhihua | Teleha, Christopher A.
Patent Number: 9150532 (2013)
Cite | Source
Identification and Structure−Activity Relationships of Chromene-Derived Selective Estrogen Receptor Modulators for Treatment of Postmenopausal Symptoms (journal article)
Jain, Nareshkumar | Xu, Jiayi | Kanojia, Ramesh M. | Du, Fuyong | Jian-Zhong, Guo | Pacia, Emmanuel | Lai, Muh-Tsann | Musto, Amy | Allan, George | Reuman, Michael | ... | Sui, Zhihua
Journal of Medicinal Chemistry, volume 52, issue 23, pages 7544-7569 (2009).
10.1021/jm900146e
Cited by (87) | Cite | Source
ChemInform Abstract: Scalable Synthesis of the VEGF‐R2 Kinase Inhibitor JNJ‐17029259 Using Ultrasound‐Mediated Addition of MeLi—CeCl3 to a Nitrile. (journal article)
Reuman, Michael | Beish, Sandra | Davis, Jeremy | Batchelor, Mark J. | Hutchings, Martin C. | Moffat, David F. C. | Connolly, Peter J. | Russell, Ronald K.
ChemInform, volume 39, issue 22 (2008).
10.1002/chin.200822161
Cite | Source
Scalable Synthesis of the VEGF-R2 Kinase Inhibitor JNJ-17029259 Using Ultrasound-Mediated Addition of MeLi−CeCl3 to a Nitrile (journal article)
Reuman, Michael | Beish, Sandra | Davis, Jeremy | Batchelor, Mark J. | Hutchings, Martin C. | Moffat, David F. C. | Connolly, Peter J. | Russell, Ronald K.
The Journal of Organic Chemistry, volume 73, issue 3, pages 1121-1123 (2008).
10.1021/jo7021372
Cited by (15) | Cite | Source
Synthesis of Tetracyclic Heterocompounds as Selective Estrogen Receptor Modulators. Part 2. Process Improvement for Scale-Up of 2,5,8-Substituted 11,12-Dihydro-5 H -6,13-dioxabenzo[3,4]cyclohepta-[1,2- a ]naphthalene Derivatives (journal article)
Li, Xun | Reuman, Michael | Russell, Ronald K. | Youells, Scott | Beish, Sandra | Hu, Zhiyong | Branum, Shawn | Jain, Nareshkumar | Sui, Zhihua
Organic Process Research & Development, volume 12, issue 1, pages 125-125 (2008).
10.1021/op700254f
Cited by (3) | Cite | Source | Open Access
Synthesis of a 5-((Aryloxy)methyl)-3-(4-(trifluoromethyl)phenyl)[1,2,4]thiadiazole Derivative: A Promising PPARα,δ Agonist (journal article)
Reuman, Michael | Hu, Zhiyong | Kuo, Gee-Hong | Li, Xun | Russell, Ronald K. | Shen, Lan | Youells, Scott | Zhang, Yongzheng
Organic Process Research & Development, volume 11, issue 6, pages 1010-1014 (2007).
10.1021/op700141u
Cited by (6) | Cite | Source
Synthesis and Identification of [1,2,4]Thiadiazole Derivatives as a New Series of Potent and Orally Active Dual Agonists of Peroxisome Proliferator-Activated Receptors α and δ (journal article)
Shen, Lan | Zhang, Yan | Wang, Aihua | Sieber-McMaster, Ellen | Chen, Xiaoli | Pelton, Patricia | Xu, Jun Z. | Yang, Maria | Zhu, Peifang | Zhou, Lubing | ... | Kuo, Gee-Hong
Journal of Medicinal Chemistry, volume 50, issue 16, pages 3954-3963 (2007).
10.1021/jm070511x
Cited by (39) | Cite | Source
Synthesis of Tetracyclic Heterocompounds as Selective Estrogen Receptor Modulators. Part 2. Process Improvement for Scale-Up Of 2,5,8-Substituted 11,12-Dihydro-5 H -6,13-dioxabenzo[3,4]cyclohepta-[1,2- a ]naphthalene Derivatives (journal article)
Li, Xun | Reuman, Michael | Russell, Ronald K. | Youells, Scott | Beish, Sandra | Hu, Zhiyong | Branum, Shawn | Jain, Nareshkumar | Sui, Zhihua
Organic Process Research & Development, volume 11, issue 4, pages 731-738 (2007).
10.1021/op700061x
Cited by (8) | Cite | Source
4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation (journal article)
Hughes, Terry V. | Emanuel, Stuart L. | Beck, Amanda K. | Wetter, Steven K. | Connolly, Peter J. | Karnachi, Prabha | Reuman, Michael | Seraj, Jabed | Fuentes-Pesquera, Angel R. | Gruninger, Robert H. | ... | Moffat, David F.C.
Bioorganic & Medicinal Chemistry Letters, volume 17, issue 12, pages 3266-3270 (2007).
10.1016/j.bmcl.2007.04.021
Cited by (42) | Cite | Source
Direct Conversion of Substituted Pyrrole‐2‐carboxylic Acid Methyl Esters to Their 2‐Carbonitrile Analogues (journal article)
Li, Xun | Reuman, Michael | Russell, Ronald K.
ChemInform, volume 38, issue 22 (2007).
10.1002/chin.200722096
Cite | Source
Synthesis of Tetracyclic Heterocompounds as Selective Estrogen Receptor Modulators. Part 1. Process Development for Scale-up of 2,5,8-Substituted 5,11-Dihydrochromeno[4,3- c ]chromene Derivatives (journal article)
Li, Xun | Reuman, Michael | Russell, Ronald K. | Adams, Richard | Ma, Robert | Branum, Shawn | Youells, Scott | Roberts, Jerry | Jain, Nareshkumar | Kanojia, Ramesh | Sui, Zhihua
Organic Process Research & Development, volume 11, issue 3, pages 414-421 (2007).
10.1021/op700020f
Cited by (11) | Cite | Source
Inhibitors of unactivated p38 MAP kinase (journal article)
Bullington, James | Argentieri, Dennis | Averill, Kristin | Carter, Demetrius | Cavender, Druie | Fahmy, Bohumila | Fan, Xiaodong | Hall, Daniel | Heintzelman, Geoffrey | Jackson, Paul | ... | Zhang, Yue-Mei
Bioorganic & Medicinal Chemistry Letters, volume 16, issue 23, pages 6102-6106 (2006).
10.1016/j.bmcl.2006.08.101
Cited by (11) | Cite | Source
Synthesis of Novel Tetracyclic Chromenes Through Carbanion Chemistry of 4‐Methyl Coumarins. (journal article)
Chen, Ningyi | Jain, Nareshkumar | Xu, Jiayi | Reuman, Michael | Li, Xun | Russell, Ronald K. | Sui, Zhihua
ChemInform, volume 37, issue 47 (2006).
10.1002/chin.200647150
Cite | Source
Synthesis of novel tetracyclic chromenes through carbanion chemistry of 4-methyl coumarins (journal article)
Chen, Ningyi | Jain, Nareshkumar | Xu, Jiayi | Reuman, Michael | Li, Xun | Russell, Ronald K. | Sui, Zhihua
Tetrahedron Letters, volume 47, issue 33, pages 5909-5913 (2006).
10.1016/j.tetlet.2006.06.047
Cited by (11) | Cite | Source
Direct Conversion of Substituted Pyrrole-2-carboxylic Acid Methyl Esters to Their 2-Carbonitrile Analogues (journal article)
Li, Xun | Reuman, Michael | K. Russell, Ronald
HETEROCYCLES, volume 70, issue 1, pages 201- (2006).
10.3987/COM-06-S(W)4
Cited by (2) | Cite | Source
A Vascular Endothelial Growth Factor Receptor-2 Kinase Inhibitor Potentiates the Activity of the Conventional Chemotherapeutic Agents Paclitaxel and Doxorubicin in Tumor Xenograft Models (journal article)
Emanuel, Stuart | Gruninger, Robert H. | Fuentes-Pesquera, Angel | Connolly, Peter J. | Seamon, Jennifer A. | Hazel, Susan | Tominovich, Rose | Hollister, Beth | Napier, Cheryl | D'Andrea, Michael R. | ... | Middleton, Steven A.
Molecular Pharmacology, volume 66, issue 3, pages 635-647 (2004).
10.1124/mol.104.000638
Cited by (48) | Cite | Source | Open Access
Antibacterial Agents, Quinolones (book chapter)
In Kirk-Othmer Encyclopedia of Chemical Technology
Reuman, M. | Lesher, G. Y.
Wiley (2000)
10.1002/0471238961.1721091418052113.a01
Cite | Source
Antipicornaviral agents (patent)
Aldous, David J. | Bailey, Thomas R. | Diana, Guy D. | Kuo, Gee-Hong | Nitz, Theodore J. | Reuman, Michael
Patent Number: 5523312 (1996)
Cited by (11) | Cite | Source
Substituted quinoline derivatives useful as antipiconaviral agents (patent)
Aldous, David J. | Bailey, Thomas R. | Diana, Guy D. | Kuo, Gee-Hong | Nitz, Theodore J. | Reuman, Michael
Patent Number: 5514692 (1996)
Cited by (10) | Cite | Source
ChemInform Abstract: Synthesis and Antibacterial Activity of Some Novel 1‐Substituted 1,4‐ Dihydro‐4‐oxo‐7‐pyridinyl‐3‐quinolinecarboxylic Acids. Potent Antistaphylococcal Agents. (journal article)
Reuman, M. | Daum, S. J. | Singh, B. | Wentland, M. P. | Perni, R. B. | Pennock, P. | Carabateas, P. M. | Gruett, M. D. | Saindane, M. T. | Dorff, P. H. | ... | Lesher, G. Y.
ChemInform, volume 26, issue 45 (1995).
10.1002/chin.199545173
Cite | Source