Lisa Crocker

ScholarGPS® ID: 78738004248589

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Cancer | Breast Cancer

Metrics Summary

Publication Count

Predicted Citations

4,620

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action (journal article) Chan, Jocelyn \| Chan, Joyce \| Shao, Lily \| Stawicki, Scott S. \| Pham, Victoria C. \| Akita, Rob W. \| Hafner, Marc \| Crocker, Lisa \| Yu, Kebing \| Koerber, James T. \| ... \| Comps-Agrar, Laetitia Journal of Biological Chemistry, volume 299, issue 1, pages 102729- (2023). 10.1016/j.jbc.2022.102729 Cite \| Source
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment (journal article) Harnoss, Jonathan M. \| Le Thomas, Adrien \| Reichelt, Mike \| Guttman, Ofer \| Wu, Thomas D. \| Marsters, Scot A. \| Shemorry, Anna \| Lawrence, David A. \| Kan, David \| Segal, Ehud \| ... \| Ashkenazi, Avi Cancer Research, volume 80, issue 11, pages 2368-2379 (2020). 10.1158/0008-5472.CAN-19-3108 Cited by (43) \| Cite \| Source
NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma (journal article) Hegde, Ganapati V \| de la Cruz, Cecile \| Giltnane, Jennifer M \| Crocker, Lisa \| Venkatanarayan, Avinashnarayan \| Schaefer, Gabriele \| Dunlap, Debra \| Hoeck, Joerg D \| Piskol, Robert \| Gnad, Florian \| ... \| Jackson, Erica L eLife, volume 8 (2019). 10.7554/eLife.46551 Cited by (8) \| Cite \| Source
Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells (journal article) Li, Guangmin \| Guo, Jun \| Shen, Ben-Quan \| Yadav, Daniela Bumbaca \| Sliwkowski, Mark X. \| Crocker, Lisa M. \| Lacap, Jennifer A. \| Phillips, Gail D. Lewis Molecular Cancer Therapeutics, volume 17, issue 7, pages 1441-1453 (2018). 10.1158/1535-7163.MCT-17-0296 Cited by (118) \| Cite \| Source \| Open Access
An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer (journal article) Bhakta, Sunil \| Crocker, Lisa M. \| Chen, Yvonne \| Hazen, Meredith \| Schutten, Melissa M. \| Li, Dongwei \| Kuijl, Coenraad \| Ohri, Rachana \| Zhong, Fiona \| Poon, Kirsten A. \| ... \| Junutula, Jagath R. Molecular Cancer Therapeutics, volume 17, issue 3, pages 638-649 (2018). 10.1158/1535-7163.MCT-17-0813 Cited by (22) \| Cite \| Source \| Open Access
Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer (journal article) Asghar, Uzma S. \| Barr, Alexis R. \| Cutts, Ros \| Beaney, Matthew \| Babina, Irina \| Sampath, Deepak \| Giltnane, Jennifer \| Lacap, Jennifer Arca \| Crocker, Lisa \| Young, Amy \| ... \| Turner, Nicholas C. Clinical Cancer Research, volume 23, issue 18, pages 5561-5572 (2017). 10.1158/1078-0432.CCR-17-0369 Cited by (188) \| Cite \| Source \| Open Access
An Antibody–Drug Conjugate Directed against Lymphocyte Antigen 6 Complex, Locus E (LY6E) Provides Robust Tumor Killing in a Wide Range of Solid Tumor Malignancies (journal article) Asundi, Jyoti \| Crocker, Lisa \| Tremayne, Jarrod \| Chang, Peter \| Sakanaka, Chie \| Tanguay, Josh \| Spencer, Susan \| Chalasani, Sreedevi \| Luis, Elizabeth \| Gascoigne, Karen \| ... \| Firestein, Ron Clinical Cancer Research, volume 21, issue 14, pages 3252-3262 (2015). 10.1158/1078-0432.CCR-15-0156 Cited by (34) \| Cite \| Source \| Open Access
An Anti-B7-H4 Antibody–Drug Conjugate for the Treatment of Breast Cancer (journal article) Leong, Steven R. \| Liang, Wei-Ching \| Wu, Yan \| Crocker, Lisa \| Cheng, Eric \| Sampath, Deepak \| Ohri, Rachana \| Raab, Helga \| Hass, Philip E. \| Pham, Thinh \| ... \| Polson, Andrew G. Molecular Pharmaceutics, volume 12, issue 6, pages 1717-1729 (2015). 10.1021/mp5007745 Cited by (53) \| Cite \| Source
Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors (journal article) Wang, Weiru \| Elkins, Kristi \| Oh, Angela \| Ho, Yen-Ching \| Wu, Jiansheng \| Li, Hong \| Xiao, Yang \| Kwong, Mandy \| Coons, Mary \| Brillantes, Bobby \| ... \| Belmont, Lisa D. PLoS ONE, volume 9, issue 10, pages e109366- (2014). 10.1371/journal.pone.0109366 Cited by (30) \| Cite \| Source \| Open Access
Amphiregulin and PTEN evoke a multimodal mechanism of acquired resistance to PI3K inhibition (journal article) Edgar, Kyle A. \| Crocker, Lisa \| Cheng, Eric \| Wagle, Marie-Claire \| Wongchenko, Matthew \| Yan, Yibing \| Wilson, Timothy R. \| Dompe, Nicholas \| Neve, Richard M. \| Belvin, Marcia \| ... \| Wallin, Jeffrey J. Genes & Cancer, volume 5, issue 3-4, pages 113-126 (2014). 10.18632/genesandcancer.10 Cited by (19) \| Cite \| Source \| Open Access
Dual Targeting of HER2-Positive Cancer with Trastuzumab Emtansine and Pertuzumab: Critical Role for Neuregulin Blockade in Antitumor Response to Combination Therapy (journal article) Phillips, Gail D. Lewis \| Fields, Carter T. \| Li, Guangmin \| Dowbenko, Donald \| Schaefer, Gabriele \| Miller, Kathy \| Andre, Fabrice \| Burris, Howard A. \| Albain, Kathy S. \| Harbeck, Nadia \| ... \| Sliwkowski, Mark X. Clinical Cancer Research, volume 20, issue 2, pages 456-468 (2014). 10.1158/1078-0432.CCR-13-0358 Cited by (153) \| Cite \| Source \| Open Access
Preclinical pharmacokinetics of MEHD7945A, a novel EGFR/HER3 dual-action antibody, and prediction of its human pharmacokinetics and efficacious clinical dose (journal article) Kamath, Amrita V. \| Lu, Dan \| Gupta, Priyanka \| Jin, Denise \| Xiang, Hong \| Wong, Anne \| Leddy, Cecilia \| Crocker, Lisa \| Schaefer, Gabriele \| Sliwkowski, Mark X. \| Damico-Beyer, Lisa A. Cancer Chemotherapy and Pharmacology, volume 69, issue 4, pages 1063-1069 (2012). 10.1007/s00280-011-1806-6 Cited by (38) \| Cite \| Source
A Two-in-One Antibody against HER3 and EGFR Has Superior Inhibitory Activity Compared with Monospecific Antibodies (journal article) Schaefer, Gabriele \| Haber, Lauric \| Crocker, Lisa M. \| Shia, Steven \| Shao, Lily \| Dowbenko, Donald \| Totpal, Klara \| Wong, Anne \| Lee, Chingwei V. \| Stawicki, Scott \| ... \| Eigenbrot, Charles Cancer Cell, volume 20, issue 4, pages 472-486 (2011). 10.1016/j.ccr.2011.09.003 Cited by (350) \| Cite \| Source \| Open Access
Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice (journal article) Jumbe, Nelson L. \| Xin, Yan \| Leipold, Douglas D. \| Crocker, Lisa \| Dugger, Debra \| Mai, Elaine \| Sliwkowski, Mark X. \| Fielder, Paul J. \| Tibbitts, Jay Journal of Pharmacokinetics and Pharmacodynamics, volume 37, issue 3, pages 221-242 (2010). 10.1007/s10928-010-9156-2 Cited by (107) \| Cite \| Source
Superior In vivo Efficacy of Afucosylated Trastuzumab in the Treatment of HER2-Amplified Breast Cancer (journal article) Junttila, Teemu T. \| Parsons, Kathryn \| Olsson, Christine \| Lu, Yanmei \| Xin, Yan \| Theriault, Julie \| Crocker, Lisa \| Pabonan, Oliver \| Baginski, Tomasz \| Meng, Gloria \| ... \| Sliwkowski, Mark X. Cancer Research, volume 70, issue 11, pages 4481-4489 (2010). 10.1158/0008-5472.CAN-09-3704 Cited by (210) \| Cite \| Source \| Open Access
Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate (journal article) Lewis Phillips, Gail D. \| Li, Guangmin \| Dugger, Debra L. \| Crocker, Lisa M. \| Parsons, Kathryn L. \| Mai, Elaine \| Blättler, Walter A. \| Lambert, John M. \| Chari, Ravi V.J. \| Lutz, Robert J. \| ... \| Sliwkowski, Mark X. Cancer Research, volume 68, issue 22, pages 9280-9290 (2008). 10.1158/0008-5472.CAN-08-1776 Cited by (1,332) \| Cite \| Source \| Open Access
A Central Role for HER3 in HER2 -Amplified Breast Cancer: Implications for Targeted Therapy (journal article) Lee-Hoeflich, Si Tuen \| Crocker, Lisa \| Yao, Evelyn \| Pham, Thinh \| Munroe, Xander \| Hoeflich, Klaus P. \| Sliwkowski, Mark X. \| Stern, Howard M. Cancer Research, volume 68, issue 14, pages 5878-5887 (2008). 10.1158/0008-5472.CAN-08-0380 Cited by (526) \| Cite \| Source \| Open Access
Cell lines and animal models of HER2 expressing tumors (patent) Crocker, Lisa \| Ross, Sarajane \| Phillips, Gail Dianne Patent Number: 20090098115 (2007) Cite \| Source
Animal model of ligand activated HER2 expressing tumors (patent) Crocker, Lisa \| Ross, Sarajane \| Phillips, Gail Dianne Patent Number: 20060212956 (2006) Cite \| Source
Vascular changes in mouse tumors following endothelial cell targeted therapy (journal article) Schmidt, Maike \| Ross, Sarajane \| Crocker, Lisa \| Peale, Franklin \| Watts, Ryan \| Ye, Weilan The FASEB Journal, volume 20, issue 5 (2006). 10.1096/fasebj.20.5.A1100-b Cite \| Source