Anna Lucia Fallacara

ScholarGPS® ID: 78580728941597

Affiliation

University of Siena, Siena, Italy

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Medicinal Chemistry | Protein Kinase Inhibitor | Chemical Synthesis | Glioblastoma

Metrics Summary

Publication Count

Predicted Citations

858

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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The Pyrazolo[3,4-d]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma (journal article) Rango, Enrico \| Pastorino, Fabio \| Brignole, Chiara \| Mancini, Arianna \| Poggialini, Federica \| Di Maria, Salvatore \| Zamperini, Claudio \| Iovenitti, Giulia \| Fallacara, Anna Lucia \| Sabetta, Samantha \| ... \| Botta, Maurizio Biomedicines, volume 10, issue 3, pages 659- (2022). 10.3390/biomedicines10030659 Cited by (6) \| Cite \| Source
Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma (journal article) Rango, Enrico \| D'Antona, Lucia \| Iovenitti, Giulia \| Brai, Annalaura \| Mancini, Arianna \| Zamperini, Claudio \| Trivisani, Claudia Immacolata \| Marianelli, Stefano \| Fallacara, Anna Lucia \| Molinari, Alessio \| ... \| Botta, Maurizio European Journal of Medicinal Chemistry, volume 223 (2021). 10.1016/j.ejmech.2021.113653 Cited by (9) \| Cite \| Source
Predictive Gene Signature for Pyrazolopyrimidine Derivative c-Src Inhibitor 10a Sensitivity in Melanoma Cells (journal article) Kucukkaraduman, Baris \| Turk, Can \| Fallacara, Anna L. \| Isbilen, Murat \| Senses, Kerem M. \| Ayyildiz, Zeynep O. \| Akbar, Muhammad W. \| Lotem, Michal \| Botta, Maurizio \| Gure, Ali O. ACS Medicinal Chemistry Letters, volume 11, issue 5, pages 928-932 (2020). 10.1021/acsmedchemlett.9b00679 Cited by (3) \| Cite \| Source
Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines (journal article) Fallacara, Anna Lucia \| Passannanti, Raffaele \| Mori, Mattia \| Iovenitti, Giulia \| Musumeci, Francesca \| Greco, Chiara \| Crespan, Emmanuele \| Kissova, Miroslava \| Maga, Giovanni \| Tarantelli, Chiara \| ... \| Schenone, Silvia European Journal of Medicinal Chemistry, volume 181 (2019). 10.1016/j.ejmech.2019.07.048 Cited by (13) \| Cite \| Source
Proton Therapy and Src Family Kinase Inhibitor Combined Treatments on U87 Human Glioblastoma Multiforme Cell Line (journal article) Cammarata, Francesco P \| Torrisi, Filippo \| Forte, Giusi I \| Minafra, Luigi \| Bravatà, Valentina \| Pisciotta, Pietro \| Savoca, Gaetano \| Calvaruso, Marco \| Petringa, Giada \| Cirrone, Giuseppe A. P. \| ... \| Russo, Giorgio International Journal of Molecular Sciences, volume 20, issue 19, pages 4745- (2019). 10.3390/ijms20194745 Cited by (29) \| Cite \| Source
An Update on JAK Inhibitors (journal article) Musumeci, Francesca \| Greco, Chiara \| Giacchello, Ilaria \| Fallacara, Anna Lucia \| Ibrahim, Munjed M. \| Grossi, Giancarlo \| Brullo, Chiara \| Schenone, Silvia Current Medicinal Chemistry, volume 26, issue 10, pages 1806-1832 (2019). 10.2174/0929867325666180327093502 Cited by (23) \| Cite \| Source
A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor (journal article) Fallacara, Anna Lucia \| Zamperini, Claudio \| Podolski-Renić, Ana \| Dinić, Jelena \| Stanković, Tijana \| Stepanović, Marija \| Mancini, Arianna \| Rango, Enrico \| Iovenitti, Giulia \| Molinari, Alessio \| ... \| Schenone, Silvia Cancers, volume 11, issue 6, pages 848- (2019). 10.3390/cancers11060848 Cited by (35) \| Cite \| Source
49. Combined treatments with Hadrontherapy – in vitro tests and preclinical approach (journal article) Russo, G. \| Pisciotta, P. \| Marchese, V. \| Cammarata, F.P. \| Minafra, L. \| Forte, G.I. \| Bravatà, V. \| Cirrone, G.A.P. \| Fallacara, A.L. \| Maccari, L. \| ... \| Cuttone, G. Physica Medica, volume 56 (2018). 10.1016/j.ejmp.2018.04.059 Cite \| Source
One-Pot Synthesis of spiro(indoline-3,4′-pyrazolo[3,4-b]pyridine)-5′-carbonitriles As p53-MDM2 Interaction Inhibitors (journal article) Ibrahim, Hany S \| Eldehna, Wagdy M \| Fallacara, Anna Lucia \| Ahmed, Esam R \| Ghabbour, Hazem A \| Elaasser, Mahmoud M \| Botta, Maurizio \| Abou-seri, Sahar M \| Abdel-Aziz, Hatem A Future Medicinal Chemistry, volume 10, issue 24, pages 2771-2789 (2018). 10.4155/fmc-2018-0288 Cited by (16) \| Cite \| Source
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment (journal article) Molinari, Alessio \| Fallacara, Anna Lucia \| Di Maria, Salvatore \| Zamperini, Claudio \| Poggialini, Federica \| Musumeci, Francesca \| Schenone, Silvia \| Angelucci, Adriano \| Colapietro, Alessandro \| Crespan, Emmanuele \| ... \| Botta, Maurizio Bioorganic & Medicinal Chemistry Letters, volume 28, issue 21, pages 3454-3457 (2018). 10.1016/j.bmcl.2018.09.024 Cited by (23) \| Cite \| Source
SMALL MOLECULES SOLVING BIG PROBLEMS: PRESENT AND FUTURE OF DRUG DISCOVERY (journal article) Fallacara, Anna Lucia \| Tris, Iuni Margaret Laura \| Belfiore, Amalia \| Botta, Maurizio Journal of the Siena Academy of Sciences, volume 9, issue 1 (2018). 10.4081/jsas.2017.7876 Cite \| Source
Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors (journal article) Francini, Cinzia Maria \| Musumeci, Francesca \| Fallacara, Anna Lucia \| Botta, Lorenzo \| Molinari, Alessio \| Artusi, Roberto \| Mennuni, Laura \| Angelucci, Adriano \| Schenone, Silvia Molecules, volume 23, issue 9, pages 2369- (2018). 10.3390/molecules23092369 Cited by (5) \| Cite \| Source \| Open Access
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction (journal article) D'Agostino, Ilaria \| Giacchello, Ilaria \| Nannetti, Giulio \| Fallacara, Anna Lucia \| Deodato, Davide \| Musumeci, Francesca \| Grossi, Giancarlo \| Palù, Giorgio \| Cau, Ylenia \| Trist, Iuni Margaret \| ... \| Botta, Maurizio European Journal of Medicinal Chemistry, volume 157 (2018). 10.1016/j.ejmech.2018.08.032 Cited by (23) \| Cite \| Source
Pyrrolo[2,3- d ]pyrimidines active as Btk inhibitors (journal article) Musumeci, Francesca \| Sanna, Monica \| Greco, Chiara \| Giacchello, Ilaria \| Fallacara, Anna Lucia \| Amato, Rosario \| Schenone, Silvia Expert Opinion on Therapeutic Patents, volume 27, issue 12, pages 1305-1318 (2017). 10.1080/13543776.2017.1355908 Cited by (10) \| Cite \| Source
Application of Molecular Modelling to Speed-up the Lead Discovery Process (book chapter) In Computational Tools for Chemical Biology Trist, Iuni M. L. \| Botta, Maurizio \| Fallacara, Anna Lucia The Royal Society of Chemistry (2017) 10.1039/9781788010139-00281 Cite \| Source
Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors (journal article) Fallacara, Anna \| Brullo, Chiara \| Grossi, Giancarlo \| Sanna, Monica \| Musumeci, Francesca \| Schenone, Silvia Current Medicinal Chemistry, volume 24, issue 999, pages 1-1 (2017). 10.2174/0929867324666170303162100 Cited by (16) \| Cite \| Source
Prodrugs of Pyrazolo[3,4- d ]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model (journal article) Vignaroli, Giulia \| Iovenitti, Giulia \| Zamperini, Claudio \| Coniglio, Federica \| Calandro, Pierpaolo \| Molinari, Alessio \| Fallacara, Anna Lucia \| Sartucci, Andrea \| Calgani, Alessia \| Colecchia, David \| ... \| Schenone, Silvia Journal of Medicinal Chemistry, volume 60, issue 14, pages 6305-6320 (2017). 10.1021/acs.jmedchem.7b00637 Cited by (28) \| Cite \| Source
Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line (journal article) Fallacara, Anna Lucia \| Mancini, Arianna \| Zamperini, Claudio \| Dreassi, Elena \| Marianelli, Stefano \| Chiariello, Mario \| Pozzi, Gianni \| Santoro, Francesco \| Botta, Maurizio \| Schenone, Silvia Bioorganic & Medicinal Chemistry Letters, volume 27, issue 14, pages 3196-3200 (2017). 10.1016/j.bmcl.2017.05.015 Cited by (21) \| Cite \| Source
Identification of new pyrrolo[2,3- d ]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma (journal article) Musumeci, Francesca \| Fallacara, Anna Lucia \| Brullo, Chiara \| Grossi, Giancarlo \| Botta, Lorenzo \| Calandro, Pierpaolo \| Chiariello, Mario \| Kissova, Miroslava \| Crespan, Emmanuele \| Maga, Giovanni \| Schenone, Silvia European Journal of Medicinal Chemistry, volume 127 (2017). 10.1016/j.ejmech.2016.12.036 Cited by (23) \| Cite \| Source
Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma (journal article) Senses, Kerem M. \| Ghasemi, Mehdi \| Akbar, Muhammad W. \| Isbilen, Murat \| Fallacara, Anna L. \| Frankenburg, Shoshana \| Schenone, Silvia \| Lotem, Michal \| Botta, Maurizio \| Gure, Ali O. MedChemComm, volume 8, issue 1, pages 88-95 (2017). 10.1039/C6MD00466K Cited by (4) \| Cite \| Source \| Open Access