Robert W. Tuman

ScholarGPS® ID: 78440123395994

Affiliation

Janssen Pharmaceutica

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Medicinal Chemistry | Angiogenesis | Protein Kinase Inhibitor

Metrics Summary

Publication Count

Predicted Citations

853

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Synergistic modulation of FLT3 kinase using a FLT3 inhibitor and a farnesyl transferase inhibitor (patent) Baumann, Christian Andrew \| Johnson, Dana L. \| Gaul, Michael David \| Tuman, Robert W. Patent Number: 8557847 (2013) Cite \| Source
Oral Coadministration of β-Glucuronidase to Increase Exposure of Extensively Glucuronidated Drugs that Undergo Enterohepatic Recirculation (journal article) Eichenbaum, Gary \| Hsu, C.-P. \| Subrahmanyam, Vangala \| Chen, Jing \| Scicinski, Jan \| Galemmo, Robert A. \| Tuman, Robert W. \| Johnson, Dana L. Journal of Pharmaceutical Sciences, volume 101, issue 7, pages 2545-2556 (2012). 10.1002/jps.23113 Cited by (8) \| Cite \| Source
Triazolopyridazine compounds (patent) Lu, Tianbao \| Alexander, Richard \| Connors, Richard W. \| Cummings, Maxwell D. \| Galemmo, Robert A. \| Hufnagel, Heather Rae \| Johnson, Dana L. \| Khalil, Ehab \| Leonard, Kristi A. \| Markotan, Thomas P. \| ... \| Tuman, Robert W. Patent Number: 8173654 (2012) Cite \| Source
Alkylquinoline and alkylquinazoline kinase modulators (patent) Baindur, Nand \| Gaul, Michael David \| Kreutter, Kevin Douglas \| Baumann, Christian Andrew \| Kim, Alexander J. \| Xu, Guozhang \| Tuman, Robert W. \| Johnson, Dana L. Patent Number: 8071768 (2011) Cited by (1) \| Cite \| Source
Triazolopyridazines as kinase modulators (patent) Lu, Tianbao \| Alexander, Richard \| Connors, Richard W. \| Cummings, Maxwell D. \| Galemmo, Robert A. \| Hufnagel, Heather Rae \| Johnson, Dana L. \| Khalil, Ehab \| Leonard, Kristi A. \| Markotan, Thomas P. \| ... \| Tuman, Robert W. Patent Number: 8030305 (2011) Cited by (8) \| Cite \| Source
N-substituted tricyclic 3-aminopyrazoles as anti-mitotic tubulin polymerization inhibitors (patent) Johnson, Dana L. \| Mei, Jay M. \| Galemmo, Robert A. \| Tuman, Robert W. \| Maharoof, Umar S. M. Patent Number: 7816390 (2010) Cite \| Source
Method of inhibiting FLT3 kinase (patent) Ballentine, Shelley K. \| Baumann, Christian Andrew \| Chen, Jinsheng \| Illig, Carl R. \| Meegalla, Sanath K. \| Rudolph, M. Jonathan \| Tuman, Robert W. \| Wall, Mark J. \| Wilson, Kenneth \| Johnson, Dana L. Patent Number: 7795279 (2010) Cited by (20) \| Cite \| Source
Acylhydrazones as kinase modulators (patent) Leonard, Kristi \| Lu, Tianbao \| Tuman, Robert W. \| Johnson, Dana L. \| Maroney, Anna C. \| Sechler, Jan L. \| Connors, Richard W. \| Alexander, Richard S. \| Cummings, Maxwell D. \| Galemmo, Robert A. \| Markotan, Thomas P. Patent Number: 7662824 (2010) Cited by (2) \| Cite \| Source
JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia (journal article) Manthey, Carl L. \| Johnson, Dana L. \| Illig, Carl R. \| Tuman, Robert W. \| Zhou, Zhao \| Baker, Judith F. \| Chaikin, Margery A. \| Donatelli, Robert R. \| Franks, Carol F. \| Zeng, Lee \| ... \| Molloy, Christopher J. Molecular Cancer Therapeutics, volume 8, issue 11, pages 3151-3161 (2009). 10.1158/1535-7163.MCT-09-0255 Cited by (96) \| Cite \| Source \| Open Access
R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies (journal article) Arts, J \| Angibaud, P \| Mariën, A \| Floren, W \| Janssens, B \| King, P \| van Dun, J \| Janssen, L \| Geerts, T \| Tuman, R W \| ... \| van Emelen, K British Journal of Cancer, volume 97, issue 10, pages 1344-1353 (2007). 10.1038/sj.bjc.6604025 Cited by (78) \| Cite \| Source \| Open Access
Angiogenesis inhibiting 5-substituted-1,2,4-thiadiazolyl derivatives (patent) Stokbroekx, Raymond Antoine \| Ceusters, Marc André \| Van der Aa, Marcel Jozef Maria \| Luyckx, Marcel Gerebernus Maria \| Willems, Marc \| Tuman, Robert W. Patent Number: 7208503 (2007) Cited by (2) \| Cite \| Source
N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders (patent) Ho, Chih Yung \| Brunmark, Bengt Anders \| Emanuel, Stuart L. \| Galemmo, Robert A. \| Johnson, Dana L. \| Ludovici, Donald William \| Maharoof, Umar \| Mei, Jay M. \| Sechler, Jan L. \| Strobel, Eric D. \| ... \| Yen, Hwa Kwo Patent Number: 20040082639 (2007) Cite \| Source
Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor (patent) Baumann, Christian Andrew \| Gaul, Michael David \| Johnson, Dana L. \| Tuman, Robert W. Patent Number: 20090197913 (2006) Cite \| Source
N -GLUCURONIDATION OF THE PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR 6,7-(DIMETHOXY-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)-(3-FLUORO-PHENYL)-AMINE BY HUMAN UDP-GLUCURONOSYLTRANSFERASES (journal article) Yan, Z. \| Caldwell, G. W. \| Gauthier, D. \| Leo, G. C. \| Mei, J. \| Ho, C. Y. \| Jones, W. J. \| Masucci, J. A. \| Tuman, R. W. \| Galemmo, R. A. \| Johnson, D. L. Drug Metabolism and Disposition, volume 34, issue 5, pages 748-755 (2006). 10.1124/dmd.106.009274 Cited by (28) \| Cite \| Source \| Open Access
(6,7-Dimethoxy-2,4-dihydroindeno[1,2- c ]pyrazol-3-yl)phenylamines: Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors with Broad Antiproliferative Activity against Tumor Cells (journal article) Ho, Chih Y. \| Ludovici, Donald W. \| Maharoof, Umar S. M. \| Mei, Jay \| Sechler, Jan L. \| Tuman, Robert W. \| Strobel, Eric D. \| Andraka, Laura \| Yen, Hwa-Kwo \| Leo, Gregory \| ... \| Galemmo, Robert A. Journal of Medicinal Chemistry, volume 48, issue 26, pages 8163-8173 (2005). 10.1021/jm050680m Cited by (34) \| Cite \| Source
Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis (journal article) D'Andrea, Michael R. \| Mei, Jay M. \| Tuman, Robert W. \| Galemmo, Robert A. \| Johnson, Dana L. Molecular Cancer Therapeutics, volume 4, issue 8, pages 1198-1204 (2005). 10.1158/1535-7163.MCT-05-0004 Cited by (10) \| Cite \| Source \| Open Access
Angiogenesis inhibiting 5-substituted-1,2,4,-thiadiazolyl derivatives (patent) Stokbroekx, Raymond Antoine \| Ceusters, Marc André \| Van der Aa, Marcel Jozef Maria \| Luyckx, Marcel Gerebernus Maria \| Willems, Marc \| Tuman, Robert W. Patent Number: 6833369 (2004) Cite \| Source
1,2,3,4-Tetrahydroquinoline-containing αVβ3 integrin antagonists with enhanced oral bioavailability (journal article) Ghosh, Shyamali \| Santulli, Rosemary J. \| Kinney, William A. \| DeCorte, Bart L. \| Liu, Li \| Lewis, Joan M. \| Proost, Jef C. \| Leo, Gregory C. \| Masucci, John \| Hageman, William E. \| ... \| Maryanoff, Bruce E. Bioorganic & Medicinal Chemistry Letters, volume 14, issue 23, pages 5937-5941 (2004). 10.1016/j.bmcl.2004.08.067 Cited by (14) \| Cite \| Source
Piperidine-containing β-arylpropionic acids as potent antagonists of αvβ3/αvβ5 integrins (journal article) De Corte, Bart L. \| Kinney, William A. \| Liu, Li \| Ghosh, Shyamali \| Brunner, Livia \| Hoekstra, William J. \| Santulli, Rosemary J. \| Tuman, Robert W. \| Baker, Judith \| Burns, Candace \| ... \| Galemmo, Robert A. Bioorganic & Medicinal Chemistry Letters, volume 14, issue 20, pages 5227-5232 (2004). 10.1016/j.bmcl.2004.06.061 Cited by (20) \| Cite \| Source
A Vascular Endothelial Growth Factor Receptor-2 Kinase Inhibitor Potentiates the Activity of the Conventional Chemotherapeutic Agents Paclitaxel and Doxorubicin in Tumor Xenograft Models (journal article) Emanuel, Stuart \| Gruninger, Robert H. \| Fuentes-Pesquera, Angel \| Connolly, Peter J. \| Seamon, Jennifer A. \| Hazel, Susan \| Tominovich, Rose \| Hollister, Beth \| Napier, Cheryl \| D'Andrea, Michael R. \| ... \| Middleton, Steven A. Molecular Pharmacology, volume 66, issue 3, pages 635-647 (2004). 10.1124/mol.104.000638 Cited by (48) \| Cite \| Source \| Open Access