Jesse E. Hanson

ScholarGPS® ID: 78139277026057

Affiliation
Genentech, Inc., South San Francisco, United States
Affiliation History

Field
Life Sciences
Discipline
Neurosciences
Top Specialties
Neuron | Alzheimer's Disease | NMDA Receptor | Glutamate Receptor | Synapse | Allosteric Modulator
Metrics Summary
Publication Count
51
Predicted Citations
4,489
Predicted h-index
31
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Differential depletion of GluN2A induces heterogeneous schizophrenia-related phenotypes in mice (journal article)
Lu, Yi | Mu, Longyu | Elstrott, Justin | Fu, Chaoying | Sun, Cailu | Su, Tonghui | Ma, Xiaofan | Yan, Jia | Jiang, Hong | Hanson, Jesse E. | ... | Chen, Yelin
eBioMedicine, volume 102 (2024).
10.1016/j.ebiom.2024.105045
Cite | Source
Targeting synapse function and loss for treatment of neurodegenerative diseases (journal article)
Dejanovic, Borislav | Sheng, Morgan | Hanson, Jesse E.
Nature Reviews Drug Discovery, volume 23, issue 1, pages 23-42 (2024).
10.1038/s41573-023-00823-1
Cited by (13) | Cite | Source
Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry (journal article)
Hanson, Jesse E. | Yuan, Hongjie | Perszyk, Riley E. | Banke, Tue G. | Xing, Hao | Tsai, Ming-Chi | Menniti, Frank S. | Traynelis, Stephen F.
Neuropsychopharmacology, volume 49, issue 1, pages 51-66 (2024).
10.1038/s41386-023-01614-3
Cited by (16) | Cite | Source
TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice (journal article)
Wang, Yuanyuan | Wu, Tiffany | Tsai, Ming-Chi | Rezzonico, Mitchell G | Abdel-Haleem, Alyaa M | Xie, Luke | Gandham, Vineela D | Ngu, Hai | Stark, Kimberly | Glock, Caspar | ... | Hanson, Jesse E
eLife, volume 12 (2023).
10.7554/eLife.83451
Cited by (3) | Cite | Source
The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration (journal article)
Zhou, Jiechao | Wade, Sarah D. | Graykowski, David | Xiao, Mei-Fang | Zhao, Binhui | Giannini, Lucia A. A. | Hanson, Jesse E. | van Swieten, John C. | Sheng, Morgan | Worley, Paul F. | Dejanovic, Borislav
Science Translational Medicine, volume 15, issue 689 (2023).
10.1126/scitranslmed.adf0141
Cited by (33) | Cite | Source
Disease-associated oligodendrocyte responses across neurodegenerative diseases (journal article)
Pandey, Shristi | Shen, Kimberle | Lee, Seung-Hye | Shen, Yun-An A. | Wang, Yuanyuan | Otero-García, Marcos | Kotova, Natalya | Vito, Stephen T. | Laufer, Benjamin I. | Newton, Dwight F. | ... | Friedman, Brad A.
Cell Reports, volume 40, issue 8, pages 111189- (2022).
10.1016/j.celrep.2022.111189
Cited by (53) | Cite | Source
Pharmacological suppression of seizure‐like activity in the PS2APP model of amyloidosis (journal article)
Weber, Martin | Imperio, Jose | Gandham, Vineela | Meilandt, William | Hanson, Jesse E. | Easton, Amy E. | Elstrott, Justin
Alzheimer's & Dementia, volume 16, issue S2 (2020).
10.1002/alz.045557
Cite | Source
Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1G93A mouse model of ALS (journal article)
Dominguez, Sara L. | Earr, Timothy | Dourado, Michelle | Ngu, Hai | Meilandt, William J. | Hanson, Jesse E.
Scientific Reports, volume 10, issue 1 (2020).
10.1038/s41598-020-72723-y
Cited by (4) | Cite | Source
PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function (journal article)
Wang, Yuanyuan | Kerrisk Campbell, Meghan | Tom, Irene | Foreman, Oded | Hanson, Jesse E. | Sheng, Morgan
Scientific Reports, volume 10, issue 1 (2020).
10.1038/s41598-020-67831-8
Cited by (16) | Cite | Source
Genome-Wide Analysis of Differential Gene Expression and Splicing in Excitatory Neurons and Interneuron Subtypes (journal article)
Huntley, Melanie A. | Srinivasan, Karpagam | Friedman, Brad A. | Wang, Tzu-Ming | Yee, Ada X. | Wang, Yuanyuan | Kaminker, Josh S. | Sheng, Morgan | Hansen, David V. | Hanson, Jesse E.
The Journal of Neuroscience, volume 40, issue 5, pages 958-973 (2020).
10.1523/JNEUROSCI.1615-19.2019
Cited by (40) | Cite | Source
GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer’s Disease Models (journal article)
Hanson, Jesse E. | Ma, Keran | Elstrott, Justin | Weber, Martin | Saillet, Sandrine | Khan, Abdullah S. | Simms, Jeffrey | Liu, Benjamin | Kim, Thomas A. | Yu, Gui-Qiu | ... | Palop, Jorge J.
Cell Reports, volume 30, issue 2, pages 381-396.e4 (2020).
10.1016/j.celrep.2019.12.030
Cited by (50) | Cite | Source
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy (journal article)
Wu, Tiffany | Dejanovic, Borislav | Gandham, Vineela D. | Gogineni, Alvin | Edmonds, Rose | Schauer, Stephen | Srinivasan, Karpagam | Huntley, Melanie A. | Wang, Yuanyuan | Wang, Tzu-Ming | ... | Hanson, Jesse E.
Cell Reports, volume 28, issue 8, pages 2111-2123.e6 (2019).
10.1016/j.celrep.2019.07.060
Cited by (249) | Cite | Source
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies (journal article)
Dejanovic, Borislav | Huntley, Melanie A. | De Mazière, Ann | Meilandt, William J. | Wu, Tiffany | Srinivasan, Karpagam | Jiang, Zhiyu | Gandham, Vineela | Friedman, Brad A. | Ngu, Hai | ... | Sheng, Morgan
Neuron, volume 100, issue 6, pages 1322-1336.e7 (2018).
10.1016/j.neuron.2018.10.014
Cited by (287) | Cite | Source
Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity (journal article)
Yao, Lulu | Grand, Teddy | Hanson, Jesse E. | Paoletti, Pierre | Zhou, Qiang
Nature Communications, volume 9, issue 1 (2018).
10.1038/s41467-018-06512-7
Cited by (27) | Cite | Source
Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice (journal article)
Dominguez, Sara L. | Hegde, Ganapati V. | Hanson, Jesse E. | Xiang, Hong | Mandikian, Danielle | Boswell, C. Andrew | Chiu, Cecilia | Wu, Yan | Tsai, Siao Ping | Fleck, Daniel | ... | Jackson, Erica L.
Scientific Reports, volume 8, issue 1 (2018).
10.1038/s41598-018-26492-4
Cited by (8) | Cite | Source | Open Access
Microglia in Alzheimer’s disease (journal article)
Hansen, David V. | Hanson, Jesse E. | Sheng, Morgan
Journal of Cell Biology, volume 217, issue 2, pages 459-472 (2018).
10.1083/jcb.201709069
Cited by (1,117) | Cite | Source | Open Access
A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain (journal article)
Wang, Tzu-Ming | Brown, Brandon M. | Deng, Lunbin | Sellers, Benjamin D. | Lupardus, Patrick J. | Wallweber, Heidi J.A. | Gustafson, Amy | Wong, Evera | Volgraf, Matthew | Schwarz, Jacob B. | ... | Hanson, Jesse E.
Neuropharmacology, volume 121 (2017).
10.1016/j.neuropharm.2017.04.041
Cited by (28) | Cite | Source | Open Access
Identifying faulty brain circuits (journal article)
Hanson, Jesse E
eLife, volume 6 (2017).
10.7554/eLife.26942
Cited by (5) | Cite | Source | Open Access
Computationally Discovered Potentiating Role of Glycans on NMDA Receptors (journal article)
Sinitskiy, Anton V. | Stanley, Nathaniel H. | Hackos, David H. | Hanson, Jesse E. | Sellers, Benjamin D. | Pande, Vijay S.
Scientific Reports, volume 7, issue 1 (2017).
10.1038/srep44578
Cited by (22) | Cite | Source | Open Access
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile (journal article)
Villemure, Elisia | Volgraf, Matthew | Jiang, Yu | Wu, Guosheng | Ly, Cuong Q. | Yuen, Po-wai | Lu, Aijun | Luo, Xifeng | Liu, Mingcui | Zhang, Shun | ... | Sellers, Benjamin D.
ACS Medicinal Chemistry Letters, volume 8, issue 1, pages 84-89 (2017).
10.1021/acsmedchemlett.6b00388
Cited by (35) | Cite | Source | Open Access