Alex Kentsis

ScholarGPS® ID: 77945714532397

Affiliation

Memorial Sloan Kettering Cancer Center, New York, United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacology and Toxicology

Top Specialties

Metrics Summary

Publication Count

122

Predicted Citations

7,242

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Proteomic Barcoding Platform for Macromolecular Screening and Delivery (journal article) Wang, Ning \| Mcneer, Nicole A. \| Eton, Elliot \| Fass, Josh \| Kentsis, Alex Journal of Proteome Research, volume 23, issue 6, pages 2067-2077 (2024). 10.1021/acs.jproteome.4c00068 Cite \| Source
Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy (journal article) Kazansky, Yaniv \| Cameron, Daniel \| Mueller, Helen S. \| Demarest, Phillip \| Zaffaroni, Nadia \| Arrighetti, Noemi \| Zuco, Valentina \| Kuwahara, Yasumichi \| Somwar, Romel \| Ladanyi, Marc \| ... \| Kentsis, Alex Cancer Discovery, volume 14, issue 6, pages 965-981 (2024). 10.1158/2159-8290.CD-23-0110 Cited by (3) \| Cite \| Source
TAZNI: A phase I/II combination trial of tazemetostat with nivolumab and ipilimumab for children with INI1-negative or SMARCA4-deficient tumors. (journal article) Yi, Joanna S. \| Czaplinski, Jeffrey \| Bhushan, Ketki \| Forrest, Suzanne J. \| Shukla, Neerav \| Mack, Stephen C. \| Hong, Andrew Lee \| Kentsis, Alex \| Stinehart, Mackenzie \| Ezrre, Suzanne \| ... \| Chi, Susan N. Journal of Clinical Oncology, volume 42, issue 16_suppl, pages TPS10077-TPS10077 (2024). 10.1200/JCO.2024.42.16_suppl.TPS10077 Cite \| Source
A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML (journal article) Dao, Tao \| Xiong, Guangyan \| Mun, Sung Soo \| Meyerberg, Jeremy \| Korontsvit, Tatyana \| Xiang, Jingyi \| Cui, Ziyou \| Chang, Aaron Y. \| Jarvis, Casey \| Cai, Winson \| ... \| Scheinberg, David A. Blood, volume 143, issue 6, pages 507-521 (2024). 10.1182/blood.2023021054 Cited by (3) \| Cite \| Source
Epigenetic Cooperativity as a Therapeutic Vulnerability in Cancer (journal article) Kazansky, Yaniv \| Kentsis, Alex Cancer Research, volume 83, issue 23, pages 3827-3829 (2023). 10.1158/0008-5472.CAN-23-2924 Cited by (1) \| Cite \| Source
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ / BUB3 (journal article) Perlee, Sarah \| Kikuchi, Sota \| Nakadai, Tomoyoshi \| Masuda, Takeshi \| Ohtsuki, Sumio \| Matsumoto, Makoto \| Rahmutulla, Bahityar \| Fukuyo, Masaki \| Cifani, Paolo \| Kentsis, Alex \| ... \| Hoshii, Takayuki EMBO reports, volume 24, issue 10 (2023). 10.15252/embr.202357108 Cited by (2) \| Cite \| Source
Integrative Proteogenomics Using ProteomeGenerator2 (journal article) Kwok, Nathaniel \| Aretz, Zita \| Takao, Sumiko \| Ser, Zheng \| Cifani, Paolo \| Kentsis, Alex Journal of Proteome Research, volume 22, issue 8, pages 2750-2764 (2023). 10.1021/acs.jproteome.3c00005 Cited by (1) \| Cite \| Source
3085 – SETD1A FUNCTION IS MEDIATED THROUGH INTERACTION WITH MITOTIC REGULATORS BUGZ/BUB3 IN LEUKEMIA (journal article) Hoshii, Takayuki \| Perlee, Sarah \| Kikuchi, Sota \| Nakadai, Tomoyoshi \| Masuda, Takeshi \| Ohtsuki, Sumio \| Matsumoto, Makoto \| Rahumtulla, Bahityar \| Fukuyo, Masaki \| Cifani, Paolo \| ... \| Kaneda, Atsushi Experimental Hematology, volume 124 (2023). 10.1016/j.exphem.2023.06.192 Cite \| Source
The AP-1/ETS Transcription Factor Network Regulates Stem Cell Quiescence and Chemotherapy Resistance in Acute Myeloid Leukemia (journal article) Takao, Sumiko \| Morell, Victor \| Brown, Fiona C. \| Koche, Richard \| Kentsis, Alex Blood, volume 140, issue Supplement 1, pages 8682-8683 (2022). 10.1182/blood-2022-165325 Cite \| Source
Quantitative Cell Proteomic Atlas: Pathway-Scale Targeted Mass Spectrometry for High-Resolution Functional Profiling of Cell Signaling (journal article) Cifani, Paolo \| Kentsis, Alex Journal of Proteome Research, volume 21, issue 10, pages 2535-2544 (2022). 10.1021/acs.jproteome.2c00223 Cite \| Source
Myb drives B-cell neoplasms and myeloid malignancies in vivo (journal article) Pieters, Tim \| Almeida, André \| T'Sas, Sara \| Lemeire, Kelly \| Hochepied, Tino \| Berx, Geert \| Kentsis, Alex \| Goossens, Steven \| Van Vlierberghe, Pieter Blood Advances, volume 6, issue 10, pages 2987-2991 (2022). 10.1182/bloodadvances.2021005955 Cited by (3) \| Cite \| Source
The menin-MLL1 interaction is a molecular dependency in NUP98 -rearranged AML (journal article) Heikamp, Emily B. \| Henrich, Jill A. \| Perner, Florian \| Wong, Eric M. \| Hatton, Charles \| Wen, Yanhe \| Barwe, Sonali P. \| Gopalakrishnapillai, Anilkumar \| Xu, Haiming \| Uckelmann, Hannah J. \| ... \| Armstrong, Scott A. Blood, volume 139, issue 6, pages 894-906 (2022). 10.1182/blood.2021012806 Cited by (49) \| Cite \| Source
Automated Multidimensional Nanoscale Chromatography for Ultrasensitive Targeted Mass Spectrometry (book chapter) In Biomedical Engineering Technologies Cifani, Paolo \| Kentsis, Alex Springer US (2022) 10.1007/978-1-0716-1803-5_11 Cite \| Source
RNA Binding Protein Syncrip Is Required for the Low-Output HSC By Sustaining Proteome Quality (journal article) Chavez, Florisela Herrejon \| Cifani, Paolo \| Pine, Alli \| Chu, Karen L \| Barin, Ersilia \| Schurer, Alexandra \| Luo, Hanzhi \| Nguyen, Diu T.T. \| Kentsis, Alex \| Leslie, Christina \| ... \| Vu, Ly P Blood, volume 138, issue Supplement 1, pages 296-296 (2021). 10.1182/blood-2021-147575 Cite \| Source
Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia (journal article) Smeenk, Leonie \| Ottema, Sophie \| Mulet-Lazaro, Roger \| Ebert, Anja \| Havermans, Marije \| Varea, Andrea Arricibita \| Fellner, Michaela \| Pastoors, Dorien \| van Herk, Stanley \| Erpelinck-Verschueren, Claudia \| ... \| Delwel, Ruud Cancer Discovery, volume 11, issue 11, pages 2868-2883 (2021). 10.1158/2159-8290.CD-20-1793 Cited by (24) \| Cite \| Source
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex (journal article) Yu, You \| Li, Shibai \| Ser, Zheng \| Sanyal, Tanmoy \| Choi, Koyi \| Wan, Bingbing \| Kuang, Huihui \| Sali, Andrej \| Kentsis, Alex \| Patel, Dinshaw J. \| Zhao, Xiaolan Proceedings of the National Academy of Sciences, volume 118, issue 19 (2021). 10.1073/pnas.2026844118 Cited by (31) \| Cite \| Source
Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics (journal article) Cifani, Paolo \| Li, Zhi \| Luo, Danmeng \| Grivainis, Mark \| Intlekofer, Andrew M. \| Fenyö, David \| Kentsis, Alex Journal of Proteome Research, volume 20, issue 4, pages 1835-1848 (2021). 10.1021/acs.jproteome.0c00638 Cited by (10) \| Cite \| Source
The C-terminal Domain of piggyBac Transposase Is Not Required for DNA Transposition (journal article) Helou, Laura \| Beauclair, Linda \| Dardente, Hugues \| Arensburger, Peter \| Buisine, Nicolas \| Jaszczyszyn, Yan \| Guillou, Florian \| Lecomte, Thierry \| Kentsis, Alex \| Bigot, Yves Journal of Molecular Biology, volume 433, issue 7, pages 166805- (2021). 10.1016/j.jmb.2020.166805 Cited by (6) \| Cite \| Source
The piggyBac-derived protein 5 (PGBD5) transposes both the closely and the distantly related piggyBac-like elements Tcr-pble and Ifp2 (journal article) Helou, Laura \| Beauclair, Linda \| Dardente, Hugues \| Piégu, Benoît \| Tsakou-Ngouafo, Louis \| Lecomte, Thierry \| Kentsis, Alex \| Pontarotti, Pierre \| Bigot, Yves Journal of Molecular Biology, volume 433, issue 7, pages 166839- (2021). 10.1016/j.jmb.2021.166839 Cited by (6) \| Cite \| Source
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia (journal article) Takao, Sumiko \| Forbes, Lauren \| Uni, Masahiro \| Cheng, Shuyuan \| Pineda, Jose Mario Bello \| Tarumoto, Yusuke \| Cifani, Paolo \| Minuesa, Gerard \| Chen, Celine \| Kharas, Michael G \| ... \| Kentsis, Alex eLife, volume 10 (2021). 10.7554/eLife.65905 Cited by (34) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Aberrant signaling in acute myeloid leukemia	Kentsis, Alex	2020	$481,665	NATIONAL CANCER INSTITUTE
Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics	Kentsis, Alex	2020	$195,315	NATIONAL CANCER INSTITUTE
Structure and function of genome plasticity in human cancer	Kentsis, Alex	2020	$519,902	NATIONAL CANCER INSTITUTE
Aberrant signaling in acute myeloid leukemia	Kentsis, Alex	2019	$467,215	NATIONAL CANCER INSTITUTE
Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics	Kentsis, Alex	2019	$234,378	NATIONAL CANCER INSTITUTE
Structure and function of genome plasticity in human cancer	Kentsis, Alex	2019	$482,122	NATIONAL CANCER INSTITUTE
Structure and function of genome plasticity in human cancer	Kentsis, Alex	2018	$497,179	NATIONAL CANCER INSTITUTE
Aberrant signaling in acute myeloid leukemia	Kentsis, Alex	2018	$231,795	NATIONAL CANCER INSTITUTE
Aberrant signaling in acute myeloid leukemia	Kentsis, Alex	2018	$459,674	NATIONAL CANCER INSTITUTE
Aberrant signaling in acute myeloid leukemia	Kentsis, Alex	2017	$232,133	NATIONAL CANCER INSTITUTE
Aberrant signaling in acute myeloid leukemia	Kentsis, Alex	2017	$459,674	NATIONAL CANCER INSTITUTE
Aberrant signaling in acute myeloid leukemia	Kentsis, Alex	2016	$459,674	NATIONAL CANCER INSTITUTE
Phosphoproteomic signatures for early detection and stratification of AML	Kentsis, Alex \| Marto, JARROD A. (contact)	2016	$190,852	NATIONAL CANCER INSTITUTE
Phosphoproteomic signatures for early detection and stratification of AML	Kentsis, Alex \| Marto, JARROD A. (contact)	2015	$228,678	NATIONAL CANCER INSTITUTE
Aberrant activation of HGF/MET signaling as a therapeutic target in AML	Kentsis, Alex	2015	$156,330	NATIONAL CANCER INSTITUTE
Aberrant activation of HGF/MET signaling as a therapeutic target in AML	Kentsis, Alex	2014	$156,330	NATIONAL CANCER INSTITUTE
Aberrant activation of HGF/MET signaling as a therapeutic target in AML	Kentsis, Alex	2013	$156,330	NATIONAL CANCER INSTITUTE
Aberrant activation of HGF/MET signaling as a therapeutic target in AML	Kentsis, Alex	2012	$142,613	NATIONAL CANCER INSTITUTE
Aberrant activation of HGF/MET signaling as a therapeutic target in AML	Kentsis, Alex	2011	$156,330	NATIONAL CANCER INSTITUTE