Benjamin F. Cravatt

ScholarGPS® ID: 76216529919765

Affiliation
Scripps Research, San Diego, United States
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Fatty Acid | Enzyme | Chemical Biology | Proteomics | Lipid | Medicinal Chemistry | Peptide | Proteome | Cancer | Biosynthesis | Metabolism | Enzyme Inhibitor | Neuron | Sleep | Active Site
Metrics Summary
Publication Count
679
Predicted Citations
91,150
Predicted h-index
163
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation (journal article)
League, Alexis F. | Yadav-Samudrala, Barkha J. | Kolagani, Ramya | Cline, Calista A. | Jacobs, Ian R. | Manke, Jonathan | Niphakis, Micah J. | Cravatt, Benjamin F. | Lichtman, Aron H. | Ignatowska-Jankowska, Bogna M. | Fitting, Sylvia
Frontiers in Immunology, volume 15 (2024).
10.3389/fimmu.2024.1374301
Cite | Source
Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders (journal article)
Liu, Zhonglin | Remsberg, Jarrett R. | Li, Haoxin | Njomen, Evert | DeMeester, Kristen E. | Tao, Yongfeng | Xia, Guoqin | Hayward, Rachel E. | Yoo, Minjin | Nguyen, Tracey | ... | Cravatt, Benjamin F.
Journal of the American Chemical Society, volume 146, issue 15, pages 10393-10406 (2024).
10.1021/jacs.3c13448
Cited by (2) | Cite | Source
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly (journal article)
Stanton, Caroline | Sun, Jie | Nutsch, Kayla | Rosarda, Jessica D. | Nguyen, Thu | Li-Ma, Chloris | Njomen, Evert | Melillo, Bruno | Kutseikin, Sergei | Saez, Enrique | ... | Bollong, Michael J.
ACS Chemical Biology, volume 19, issue 2, pages 254-265 (2024).
10.1021/acschembio.3c00330
Cited by (1) | Cite | Source
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2 (journal article)
Tao, Yongfeng | Felber, Jan G. | Zou, Zhongyu | Njomen, Evert | Remsberg, Jarrett R. | Ogasawara, Daisuke | Ye, Chang | Melillo, Bruno | Schreiber, Stuart L. | He, Chuan | ... | Cravatt, Benjamin F.
Angewandte Chemie International Edition, volume 62, issue 51 (2023).
10.1002/anie.202311924
Cited by (9) | Cite | Source
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2 (journal article)
Tao, Yongfeng | Felber, Jan G. | Zou, Zhongyu | Njomen, Evert | Remsberg, Jarrett R. | Ogasawara, Daisuke | Ye, Chang | Melillo, Bruno | Schreiber, Stuart L. | He, Chuan | ... | Cravatt, Benjamin F.
Angewandte Chemie, volume 135, issue 51 (2023).
10.1002/ange.202311924
Cite | Source
Sexually dimorphic effects of monoacylglycerol lipase inhibitor MJN110 on stress‐related behaviour and drinking in Marchigian Sardinian alcohol‐preferring rats (journal article)
Vozella, Valentina | Cruz, Bryan | Feldman, Hannah C. | Bullard, Ryan | Bianchi, Paula C. | Natividad, Luis A. | Cravatt, Benjamin F. | Zorrilla, Eric P. | Ciccocioppo, Roberto | Roberto, Marisa
British Journal of Pharmacology, volume 180, issue 24, pages 3130-3145 (2023).
10.1111/bph.16197
Cited by (1) | Cite | Source
Assigning functionality to cysteines by base editing of cancer dependency genes (journal article)
Li, Haoxin | Ma, Tiantai | Remsberg, Jarrett R. | Won, Sang Joon | DeMeester, Kristen E. | Njomen, Evert | Ogasawara, Daisuke | Zhao, Kevin T. | Huang, Tony P. | Lu, Bingwen | ... | Cravatt, Benjamin F.
Nature Chemical Biology, volume 19, issue 11, pages 1320-1330 (2023).
10.1038/s41589-023-01428-w
Cited by (9) | Cite | Source
Richard Lerner – Mentor, Colleague, and Friend (journal article)
Cravatt, Benjamin F.
Israel Journal of Chemistry, volume 63, issue 10-11 (2023).
10.1002/ijch.202300090
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Dimethyl fumarate inhibits ZNF217 and can be beneficial in a subset of estrogen receptor positive breast cancers (journal article)
Sharma, Tanu | Zhang, Yuanjin | Zigrossi, Alexandra | Cravatt, Benjamin F. | Kastrati, Irida
Breast Cancer Research and Treatment, volume 201, issue 3, pages 561-570 (2023).
10.1007/s10549-023-07037-4
Cite | Source
Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities (journal article)
Zhang, Yuxiang | Remillard, David | Onubogu, Ugoma | Karakyriakou, Barbara | Asiaban, Joshua N. | Ramos, Anissa R. | Bowland, Kirsten | Bishop, Timothy R. | Barta, Paige A. | Nance, Stephanie | ... | Erb, Michael A.
Nature Structural & Molecular Biology, volume 30, issue 8, pages 1160-1171 (2023).
10.1038/s41594-023-01041-4
Cited by (7) | Cite | Source
Remodeling oncogenic transcriptomes by small molecules targeting NONO (journal article)
Kathman, Stefan G. | Koo, Seong Joo | Lindsey, Garrett L. | Her, Hsuan-Lin | Blue, Steven M. | Li, Haoxin | Jaensch, Steffen | Remsberg, Jarrett R. | Ahn, Kay | Yeo, Gene W. | ... | Cravatt, Benjamin F.
Nature Chemical Biology, volume 19, issue 7, pages 825-836 (2023).
10.1038/s41589-023-01270-0
Cited by (20) | Cite | Source
Activity‐Based Protein Profiling – Finding General Solutions to Specific Problems (journal article)
Cravatt, Benjamin F.
Israel Journal of Chemistry, volume 63, issue 3-4 (2023).
10.1002/ijch.202300029
Cited by (7) | Cite | Source
TMEM164 is an acyltransferase that forms ferroptotic C20:4 ether phospholipids (journal article)
Reed, Alex | Ware, Timothy | Li, Haoxin | Fernando Bazan, J. | Cravatt, Benjamin F.
Nature Chemical Biology, volume 19, issue 3, pages 378-388 (2023).
10.1038/s41589-022-01253-7
Cited by (24) | Cite | Source
Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine (journal article)
Kavanagh, Madeline E. | Horning, Benjamin D. | Khattri, Roli | Roy, Nilotpal | Lu, Justine P. | Whitby, Landon R. | Ye, Elva | Brannon, Jaclyn C. | Parker, Albert | Chick, Joel M. | ... | Cravatt, Benjamin F.
Nature Chemical Biology, volume 18, issue 12, pages 1388-1398 (2022).
10.1038/s41589-022-01098-0
Cited by (35) | Cite | Source
Titelbild: Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 (Angew. Chem. 47/2022) (journal article)
Carvalho, Luís A. R. | Ross, Breyan | Fehr, Lorenz | Bolgi, Oguz | Wöhrle, Svenja | Lum, Kenneth M. | Podlesainski, David | Vieira, Andreia C. | Kiefersauer, Reiner | Félix, Rita | ... | Moreira, Rui
Angewandte Chemie, volume 134, issue 47 (2022).
10.1002/ange.202213804
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Cover Picture: Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 (Angew. Chem. Int. Ed. 47/2022) (journal article)
Carvalho, Luís A. R. | Ross, Breyan | Fehr, Lorenz | Bolgi, Oguz | Wöhrle, Svenja | Lum, Kenneth M. | Podlesainski, David | Vieira, Andreia C. | Kiefersauer, Reiner | Félix, Rita | ... | Moreira, Rui
Angewandte Chemie International Edition, volume 61, issue 47 (2022).
10.1002/anie.202213804
Cite | Source
Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 (journal article)
Carvalho, Luís A. R. | Ross, Breyan | Fehr, Lorenz | Bolgi, Oguz | Wöhrle, Svenja | Lum, Kenneth M. | Podlesainski, David | Vieira, Andreia C. | Kiefersauer, Reiner | Félix, Rita | ... | Moreira, Rui
Angewandte Chemie International Edition, volume 61, issue 47 (2022).
10.1002/anie.202210498
Cited by (4) | Cite | Source
Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 (journal article)
Carvalho, Luís A. R. | Ross, Breyan | Fehr, Lorenz | Bolgi, Oguz | Wöhrle, Svenja | Lum, Kenneth M. | Podlesainski, David | Vieira, Andreia C. | Kiefersauer, Reiner | Félix, Rita | ... | Moreira, Rui
Angewandte Chemie, volume 134, issue 47 (2022).
10.1002/ange.202210498
Cited by (1) | Cite | Source
Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1 (journal article)
Tao, Yongfeng | Remillard, David | Vinogradova, Ekaterina V. | Yokoyama, Minoru | Banchenko, Sofia | Schwefel, David | Melillo, Bruno | Schreiber, Stuart L. | Zhang, Xiaoyu | Cravatt, Benjamin F.
Journal of the American Chemical Society, volume 144, issue 40, pages 18688-18699 (2022).
10.1021/jacs.2c08964
Cited by (41) | Cite | Source
Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides (journal article)
Li, Fu-Long | Fu, Vivian | Liu, Guangbo | Tang, Tracy | Konradi, Andrei W. | Peng, Xiao | Kemper, Esther | Cravatt, Benjamin F. | Franklin, J. Matthew | Wu, Zhengming | ... | Guan, Kun-Liang
Nature Chemical Biology, volume 18, issue 10, pages 1076-1086 (2022).
10.1038/s41589-022-01061-z
Cited by (19) | Cite | Source