Irma B. Stowe

ScholarGPS® ID: 76059774667955

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Inflammasome

Metrics Summary

Publication Count

Predicted Citations

2,446

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function (journal article) Davies, Christopher W. \| Stowe, Irma \| Phung, Qui T. \| Ho, Hoangdung \| Bakalarski, Corey E. \| Gupta, Aaron \| Zhang, Yingnan \| Lill, Jennie R. \| Payandeh, Jian \| Kayagaki, Nobuhiko \| Koerber, James T. Proceedings of the National Academy of Sciences, volume 118, issue 12 (2021). 10.1073/pnas.2018024118 Cited by (9) \| Cite \| Source
MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition (journal article) Vande Walle, Lieselotte \| Stowe, Irma B. \| Šácha, Pavel \| Lee, Bettina L. \| Demon, Dieter \| Fossoul, Amelie \| Van Hauwermeiren, Filip \| Saavedra, Pedro H. V. \| Šimon, Petr \| Šubrt, Vladimír \| ... \| Lamkanfi, Mohamed PLOS Biology, volume 17, issue 9, pages e3000354- (2019). 10.1371/journal.pbio.3000354 Cited by (94) \| Cite \| Source
IRF2 transcriptionally induces GSDMD expression for pyroptosis (journal article) Kayagaki, Nobuhiko \| Lee, Bettina L. \| Stowe, Irma B. \| Kornfeld, Opher S. \| O'Rourke, Karen \| Mirrashidi, Kathleen M. \| Haley, Benjamin \| Watanabe, Colin \| Roose-Girma, Merone \| Modrusan, Zora \| ... \| Dixit, Vishva M. Science Signaling, volume 12, issue 582 (2019). 10.1126/scisignal.aax4917 Cited by (117) \| Cite \| Source
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation (journal article) Lee, Bettina L. \| Stowe, Irma B. \| Gupta, Aaron \| Kornfeld, Opher S. \| Roose-Girma, Merone \| Anderson, Keith \| Warming, Søren \| Zhang, Juan \| Lee, Wyne P. \| Kayagaki, Nobuhiko Journal of Experimental Medicine, volume 215, issue 9, pages 2279-2288 (2018). 10.1084/jem.20180589 Cited by (114) \| Cite \| Source \| Open Access
ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages (journal article) Lee, Bettina L. \| Mirrashidi, Kathleen M. \| Stowe, Irma B. \| Kummerfeld, Sarah K. \| Watanabe, Colin \| Haley, Benjamin \| Cuellar, Trinna L. \| Reichelt, Michael \| Kayagaki, Nobuhiko Scientific Reports, volume 8, issue 1 (2018). 10.1038/s41598-018-21998-3 Cited by (97) \| Cite \| Source \| Open Access
Caspase‐11: arming the guards against bacterial infection (journal article) Stowe, Irma \| Lee, Bettina \| Kayagaki, Nobuhiko Immunological Reviews, volume 265, issue 1, pages 75-84 (2015). 10.1111/imr.12292 Cited by (54) \| Cite \| Source
Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4 (journal article) Kayagaki, Nobuhiko \| Wong, Michael T. \| Stowe, Irma B. \| Ramani, Sree Ranjani \| Gonzalez, Lino C. \| Akashi-Takamura, Sachiko \| Miyake, Kensuke \| Zhang, Juan \| Lee, Wyne P. \| Muszyński, Artur \| ... \| Dixit, Vishva M. Science, volume 341, issue 6151, pages 1246-1249 (2013). 10.1126/science.1240248 Cited by (1,172) \| Cite \| Source
A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1 (journal article) Stowe, Irma B. \| Mercado, Ellen L. \| Stowe, Timothy R. \| Bell, Erika L. \| Oses-Prieto, Juan A. \| Hernández, Hilda \| Burlingame, Alma L. \| McCormick, Frank Genes & Development, volume 26, issue 13, pages 1421-1426 (2012). 10.1101/gad.190876.112 Cited by (118) \| Cite \| Source \| Open Access