Rosemary Santulli

ScholarGPS® ID: 75791329257190

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Medicine

Discipline

Cardiology

Top Specialties

Ovary | Testosterone | Prostaglandin | Glycoprotein | Hormone

Metrics Summary

Publication Count

Predicted Citations

3,466

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes (journal article) Xu, Guozhang \| Gaul, Michael D. \| Song, Fengbin \| Du, Fuyong \| Liang, Yin \| DesJarlais, Renee L. \| DiLoreto, Karen \| Shook, Brian \| Rentzeperis, Dennis \| Santulli, Rosie \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 29, issue 20, pages 126668- (2019). 10.1016/j.bmcl.2019.126668 Cited by (3) \| Cite \| Source
Design, synthesis and structure activity relationships of indazole and indole derivatives as potent glucagon receptor antagonists (journal article) Song, Fengbin \| Xu, Guozhang \| Gaul, Michael D. \| Zhao, Baoping \| Lu, Tianbao \| Zhang, Rui \| DesJarlais, Renee L. \| DiLoreto, Karen \| Huebert, Norman \| Shook, Brian \| ... \| Demarest, Keith Bioorganic & Medicinal Chemistry Letters, volume 29, issue 15, pages 1974-1980 (2019). 10.1016/j.bmcl.2019.05.036 Cited by (15) \| Cite \| Source
Synthesis and Biological Evaluation of 1,2,4-Triazolo[2,3-a]pyrrole Derivatives as Alpha-4 ( α4) Integrin Antagonists (journal article) Lawson, Edward \| Kinney, William \| Santulli, Rosemary \| Fisher, Carol \| Damiano, Bruce \| Maryanoff, Bruce Letters in Drug Design & Discovery, volume 2, issue 8, pages 601-605 (2005). 10.2174/157018005774717280 Cited by (5) \| Cite \| Source
Structure-Function Study of Quinazolinone-Based Vitronectin Receptor (αVβ3) Antagonists: Computer-Assisted Analysis of Ligand-Receptor Interactions (journal article) Lawson, Edward \| Kinney, William \| Costanzo, Michael \| Hoekstra, William \| Kauffman, Jack \| Luci, Diane \| Santulli, Rosemary \| Tounge, Brett \| Yabut, Stephen \| Andrade-Gordon, Patricia Letters in Drug Design & Discovery, volume 1, issue 1, pages 14-18 (2004). 10.2174/1570180043485644 Cited by (8) \| Cite \| Source
Arginine-Specific Protease from Porphyromonas gingivalis Activates Protease-Activated Receptors on Human Oral Epithelial Cells and Induces Interleukin-6 Secretion (journal article) Lourbakos, Afrodite \| Potempa, Jan \| Travis, James \| D'Andrea, Michael R. \| Andrade-Gordon, Patricia \| Santulli, Rosemary \| Mackie, Eleanor J. \| Pike, Robert N. Infection and Immunity, volume 69, issue 8, pages 5121-5130 (2001). 10.1128/IAI.69.8.5121-5130.2001 Cited by (207) \| Cite \| Source \| Open Access
Activation of protease-activated receptors by gingipains fromPorphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity (journal article) Lourbakos, Afrodite \| Yuan, YuPing \| Jenkins, Alison L. \| Travis, James \| Andrade-Gordon, Patricia \| Santulli, Rosemary \| Potempa, Jan \| Pike, Robert N. Blood, volume 97, issue 12, pages 3790-3797 (2001). 10.1182/blood.V97.12.3790 Cited by (192) \| Cite \| Source \| Open Access
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor (journal article) Andrade-Gordon, Patricia \| Maryanoff, Bruce E. \| Derian, Claudia K. \| Zhang, Han-Cheng \| Addo, Michael F. \| Darrow, Andrew L. \| Eckardt, Annette J. \| Hoekstra, William J. \| McComsey, David F. \| Oksenberg, Donna \| ... \| White, Kimberly B. Proceedings of the National Academy of Sciences, volume 96, issue 22, pages 12257-12262 (1999). 10.1073/pnas.96.22.12257 Cited by (166) \| Cite \| Source \| Open Access
Characterization of Protease-activated Receptor-2 Immunoreactivity in Normal Human Tissues (journal article) R. D'Andrea, Michael \| Derian, Claudia K. \| Leturcq, Didier \| Baker, Sherry M. \| Brunmark, Anders \| Ling, Ping \| Darrow, Andrew L. \| Santulli, Rosemary J. \| Brass, Lawrence F. \| Andrade–Gordon, Patricia Journal of Histochemistry & Cytochemistry, volume 46, issue 2, pages 157-164 (1998). 10.1177/002215549804600204 Cited by (289) \| Cite \| Source
Protease‐Activated Receptor‐2 (PAR‐2) Is Present in the Rat Hippocampus and Is Associated with Neurodegeneration (journal article) Smith‐Swintosky, Virginia L. \| Cheo‐Isaacs, Catherine T. \| D'Andrea, Michael R. \| Santulli, Rosemary J. \| Darrow, Andrew L. \| Andrade‐Gordon, Patricia Journal of Neurochemistry, volume 69, issue 5, pages 1890-1896 (1997). 10.1046/j.1471-4159.1997.69051890.x Cited by (96) \| Cite \| Source \| Open Access
Protease-activated receptor-2 (PAR-2) is present in the rat hippocampus and is associated with neurodegeneration. (journal article) Smith-Swintosky, V L \| Cheo-Isaacs, C T \| D'Andrea, M R \| Santulli, R J \| Darrow, A L \| Andrade-Gordon, P Journal of neurochemistry, volume 69, issue 5 (1997). Cite
Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes. (journal article) Santulli, R J \| Derian, C K \| Darrow, A L \| Tomko, K A \| Eckardt, A J \| Seiberg, M \| Scarborough, R M \| Andrade-Gordon, P Proceedings of the National Academy of Sciences, volume 92, issue 20, pages 9151-9155 (1995). 10.1073/pnas.92.20.9151 Cited by (155) \| Cite \| Source \| Open Access
Species differences in platelet responses to thrombin and SFLLRN. Receptor-mediated calcium mobilization and aggregation, and regulation by protein kinases (journal article) Derian, Claudia K. \| Santulli, Rosemary J. \| Tomko, Karen A. \| Haertlein, Barbara J. \| Andrade-Gordon, Patricia Thrombosis Research, volume 78, issue 6, pages 505-519 (1995). 10.1016/0049-3848(95)00084-5 Cited by (64) \| Cite \| Source
Testicular Steroidogenesis in the Aging Brown Norway Rat (journal article) Zirkin, Barry R. \| Santulli, Rosemary \| Strandberg, John D. \| Wright, William W. \| Ewing, Larry L. Journal of Andrology, volume 14, issue 2, pages 118-123 (1993). 10.1002/j.1939-4640.1993.tb01663.x Cited by (94) \| Cite \| Source
The Effect of Testosterone Withdrawal and Subsequent Germ Cell Depletion on Transferrin and Sulfated Glycoprotein-2 Messenger Ribonucleic Acid Levels in the Adult Rat Testis1 (journal article) Roberts, Kenneth P. \| Santulli, Rosemary \| Seiden, Jan \| Zirkin, Barry R. Biology of Reproduction, volume 47, issue 1, pages 92-96 (1992). 10.1095/biolreprod47.1.92 Cited by (21) \| Cite \| Source
The effect of testosterone withdrawal and subsequent germ cell depletion on transferrin and sulfated glycoprotein-2 messenger ribonucleic acid levels in the adult rat testis. (journal article) Roberts, K P \| Santulli, R \| Seiden, J \| Zirkin, B R Biology of reproduction, volume 47, issue 1 (1992). Cite
Regulation of Sertoli Cell Transferrin and Sulfated Glycoprotein-2 Messenger Ribonucleic Acid Levels during the Restoration of Spermatogenesis in the Adult Hypophysectomized Rat* (journal article) Roberts, Kenneth P. \| Awoniyi, Caleb A. \| Santulli, Rosemary \| Zirkin, Barry R. Endocrinology, volume 129, issue 6, pages 3417-3423 (1991). 10.1210/endo-129-6-3417 Cited by (31) \| Cite \| Source
Does Ethane 1,2‐Dimethanesulphonate (EDS) Have a Direct Cytotoxic Effect on the Seminiferous Epithelium of the Rat Testis? (journal article) Sprando, Robert L. \| Santulli, Rosemary \| Awoniyi, Caleb A. \| Ewing, Larry L. \| Zirkin, Barry R. Journal of Andrology, volume 11, issue 4, pages 344-352 (1990). 10.1002/j.1939-4640.1990.tb00155.x Cited by (23) \| Cite \| Source
Restoration of Spermatogenesis by Exogenously Administered Testosterone in Rats Made Azoospermic by Hypophysectomy or Withdrawal of Luteinizing Hormone Alone* (journal article) Awoniyi, Caleb A. \| Sprando, Robert L. \| Santulli, Rosemary \| Chandrashekar, Varadaraj \| Ewing, Larry L. \| Zirkin, Barry R. Endocrinology, volume 127, issue 1, pages 177-184 (1990). 10.1210/endo-127-1-177 Cited by (69) \| Cite \| Source
To What Extent Can Spermatogenesis Be Maintained in the Hypophysectomized Adult Rat Testis with Exogenously Administered Testosterone?* (journal article) Santulli, Rosemary \| Sprando, Robert L. \| Awoniyi, Caleb A. \| Ewing, Larry L. \| Zirkin, Barry R. Endocrinology, volume 126, issue 1, pages 95-101 (1990). 10.1210/endo-126-1-95 Cited by (59) \| Cite \| Source
Quantitative Restoration of Advanced Spermatogenic Cells in Adult Male Rats Made Azoospermic by Active Immunization against Luteinizing Hormone or Gonadotropin-Releasing Hormone* (journal article) Awoniyi, C. A. \| Santulli, R. \| Chandrashekar, V. \| Schanbacher, B. D. \| Zirkin, B. R. Endocrinology, volume 125, issue 3, pages 1303-1309 (1989). 10.1210/endo-125-3-1303 Cited by (80) \| Cite \| Source