Lawren C. Wu

ScholarGPS® ID: 74584806975908

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Medicine

Discipline

Immunology

Top Specialties

Antibody | Asthma | Allergy | Inflammation

Metrics Summary

Publication Count

Predicted Citations

5,425

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Anti-tryptase antibodies, compositions thereof, and uses thereof (patent) Chen, Xiaocheng \| Dennis, Mark \| Jackman, Janet \| Koerber, James T. \| Lu, Mason \| Maun, Henry R. \| Rajapaksa, Kathila \| Ramanujan, Saroja \| Staton, Tracy \| Wu, Lawren \| Yi, Tangsheng Patent Number: 10752703 (2020) Cite \| Source
Anti-tryptase antibodies, compositions thereof, and uses thereof (patent) Chen, Xiaocheng \| Dennis, Mark \| Jackman, Janet \| Koerber, James T. \| Lu, Mason \| Maun, Henry R. \| Rajapaksa, Kathila \| Ramanujan, Saroja \| Staton, Tracy \| Wu, Lawren \| Yi, Tangsheng Patent Number: 10738131 (2020) Cite \| Source
A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma (journal article) Shikotra, Aarti \| Choy, David F. \| Siddiqui, Salman \| Arthur, Greer \| Nagarkar, Deepti R. \| Jia, Guiquan \| Wright, Adam K. A. \| Ohri, Chandra M. \| Doran, Emma \| Butler, Claire A. \| ... \| Bradding, Peter The Journal of Immunology, volume 198, issue 8, pages 3307-3317 (2017). 10.4049/jimmunol.1600606 Cited by (27) \| Cite \| Source
Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses (journal article) Li, Yanchuan \| Wang, Hui \| Zhou, Xiaofei \| Xie, Xiaoping \| Chen, Xiang \| Jie, Zuliang \| Zou, Qiang \| Hu, Hongbo \| Zhu, Lele \| Cheng, Xuhong \| ... \| Sun, Shao-Cong Scientific Reports, volume 6, issue 1 (2016). 10.1038/srep22115 Cited by (52) \| Cite \| Source \| Open Access
Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells (journal article) Katakam, Anand K. \| Brightbill, Hans \| Franci, Christian \| Kung, Chung \| Nunez, Victor \| Jones, Charles \| Peng, Ivan \| Jeet, Surinder \| Wu, Lawren C. \| Mellman, Ira \| ... \| Austin, Cary D. Proceedings of the National Academy of Sciences, volume 112, issue 47, pages 14664-14669 (2015). 10.1073/pnas.1520627112 Cited by (36) \| Cite \| Source \| Open Access
CEACAM6-high airway neutrophils and epithelial cells are a feature of severe asthma (conference) Shikotra, Aarti \| Choy, David \| Siddiqui, Salman \| Arthur, Greer \| Nagarkar, Deepti \| Guiquan, Jia \| Ohri, Chandra \| Doran, Emma \| Butler, Claire \| Hargadon, Beverley \| ... \| Bradding, Peter Annual Congress 2015 (2015) 10.1183/13993003.congress-2015.PA910 Cited by (1) \| Cite \| Source
Conditional Deletion of NF-κB–Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation (journal article) Brightbill, Hans D. \| Jackman, Janet K. \| Suto, Eric \| Kennedy, Heather \| Jones, Charles \| Chalasani, Sreedevi \| Lin, Zhonghua \| Tam, Lucinda \| Roose-Girma, Meron \| Balazs, Mercedesz \| ... \| Wu, Lawren C. The Journal of Immunology, volume 195, issue 3, pages 953-964 (2015). 10.4049/jimmunol.1401514 Cited by (48) \| Cite \| Source \| Open Access
Conditional Deletion of NF-κB-Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation. (journal article) Brightbill, Hans D \| Jackman, Janet K \| Suto, Eric \| Kennedy, Heather \| Jones, Charles \| Chalasani, Sreedevi \| Lin, Zhonghua \| Tam, Lucinda \| Roose-Girma, Meron \| Balazs, Mercedesz \| ... \| Wu, Lawren C Journal of immunology (Baltimore, Md. : 1950), volume 195, issue 3 (2015). Cited by (1) \| Cite
Targeting IgE production in mice and humans (journal article) Wu, Lawren C \| Scheerens, Heleen Current Opinion in Immunology, volume 31 (2014). 10.1016/j.coi.2014.08.001 Cited by (49) \| Cite \| Source \| Open Access
Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production (journal article) Gauvreau, Gail M. \| Harris, Jeffrey M. \| Boulet, Louis-Philippe \| Scheerens, Heleen \| Fitzgerald, J. Mark \| Putnam, Wendy S. \| Cockcroft, Donald W. \| Davis, Beth E. \| Leigh, Richard \| Zheng, Yanan \| ... \| O’Byrne, Paul M. Science Translational Medicine, volume 6, issue 243 (2014). 10.1126/scitranslmed.3008961 Cited by (103) \| Cite \| Source
Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts (journal article) Chandriani, Sanjay \| DePianto, Daryle J. \| N’Diaye, Elsa N. \| Abbas, Alexander R. \| Jackman, Janet \| Bevers, Jack \| Ramirez-Carrozzi, Vladimir \| Pappu, Rajita \| Kauder, Steven E. \| Toy, Karen \| ... \| Arron, Joseph R. The Journal of Immunology, volume 193, issue 1, pages 111-119 (2014). 10.4049/jimmunol.1301761 Cited by (54) \| Cite \| Source \| Open Access
Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors (journal article) Pastor, Richard M. \| Burch, Jason D. \| Magnuson, Steven \| Ortwine, Daniel F. \| Chen, Yuan \| De La Torre, Kelly \| Ding, Xiao \| Eigenbrot, Charles \| Johnson, Adam \| Liimatta, Marya \| ... \| Pei, Zhonghua Bioorganic & Medicinal Chemistry Letters, volume 24, issue 11, pages 2448-2452 (2014). 10.1016/j.bmcl.2014.04.023 Cited by (16) \| Cite \| Source
Defective CD40‐dependent antigen cross‐priming of CD8+ T cells in mice with conditional deletion of NF‐κB‐inducing kinase (146.11) (journal article) Katakam, Anand \| Brightbill, Hans \| Franci, Christian \| Wu, Lawren \| Mellman, Ira \| Delamarre, Lelia \| Austin, Cary The FASEB Journal, volume 28, issue S1 (2014). 10.1096/fasebj.28.1_supplement.146.11 Cite \| Source
The production and regulation of IgE by the immune system (journal article) Wu, Lawren C. \| Zarrin, Ali A. Nature Reviews Immunology, volume 14, issue 4, pages 247-259 (2014). 10.1038/nri3632 Cited by (216) \| Cite \| Source
Therapeutic Targeting of Type 2 Inflammation for the Treatment of Severe Asthma (journal article) Wu, Lawren \| Arron, Joseph \| Harris, Jeffrey \| Matthews, John \| Rosen, Karin Clinical Anti-Inflammatory & Anti-Allergy Drugs, volume 1, issue 1, pages 2-10 (2014). 10.2174/2212703801999131206110837 Cite \| Source
Quilizumab is an Afucosylated Humanized Anti-M1 Prime Therapeutic Antibody (journal article) Brightbill, Hans \| Lin, Yuwen \| Lin, Zhonghua \| Tan, Martha \| Meng, Y. \| Balazs, Mercedesz \| Chung, Shan \| Wu, Lawren Clinical Anti-Inflammatory & Anti-Allergy Drugs, volume 1, issue 1, pages 24-31 (2014). 10.2174/22127038114019990003 Cited by (20) \| Cite \| Source
Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells (journal article) Altin, John A. \| Daley, Stephen R. \| Howitt, Jason \| Rickards, Helen J. \| Batkin, Alison K. \| Horikawa, Keisuke \| Prasad, Simon J. \| Nelms, Keats A. \| Kumar, Sharad \| Wu, Lawren C. \| ... \| Goodnow, Christopher C. Proceedings of the National Academy of Sciences, volume 111, issue 6, pages 2067-2074 (2014). 10.1073/pnas.1322739111 Cited by (19) \| Cite \| Source \| Open Access
Apoptotic anti-IgE antibodies (patent) Wu, Lawren \| Balazs, Mercedesz \| Brightbill, Hans \| Chan, Andrew \| Chen, Yvonne \| Chuntharapai, Anan \| Dennis, Mark \| Wong, Terence Patent Number: 8632775 (2014) Cited by (2) \| Cite \| Source
Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts. (journal article) Chandriani, Sanjay \| DePianto, Daryle J \| N'Diaye, Elsa N \| Abbas, Alexander R \| Jackman, Janet \| Bevers, Jack \| Ramirez-Carrozzi, Vladimir \| Pappu, Rajita \| Kauder, Steven E \| Toy, Karen \| ... \| Arron, Joseph R Journal of immunology (Baltimore, Md. : 1950), volume 193, issue 1 (2014). Cite
Nucleic acid encoding apoptotic anti-IgE antibodies (patent) Chuntharapai, Anan \| Chan, Andy \| Brightbill, Hans \| Wu, Lawren \| Dennis, Mark \| Balazs, Mercedesz \| Wong, Terence \| Chen, Yvonne Patent Number: 8618274 (2013) Cited by (3) \| Cite \| Source