Ashis K. Saha

ScholarGPS® ID: 73993743872269

Affiliation

Praecis Pharmaceuticals, Inc.

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Medicinal Chemistry | Chemical Synthesis

Metrics Summary

Publication Count

Predicted Citations

255

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Benzofuran Derivatives as Potent, Orally Active S1P1 Receptor Agonists: A Preclinical Lead Molecule for MS (journal article) Saha, Ashis K. \| Yu, Xiang \| Lin, Jian \| Lobera, Mercedes \| Sharadendu, Anurag \| Chereku, Srinivas \| Schutz, Nili \| Segal, Dalia \| Marantz, Yael \| McCauley, Dilara \| ... \| Xu, Han ACS Medicinal Chemistry Letters, volume 2, issue 2, pages 97-101 (2011). 10.1021/ml100227q Cited by (33) \| Cite \| Source \| Open Access
Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists (journal article) Evindar, Ghotas \| Bernier, Sylvie G. \| Doyle, Elisabeth \| Kavarana, Malcolm J. \| Satz, Alexander L. \| Lorusso, Jeanine \| Blanchette, Heather S. \| Saha, Ashis K. \| Hannig, Gerhard \| Morgan, Barry A. \| Westlin, William F. Bioorganic & Medicinal Chemistry Letters, volume 20, issue 8, pages 2520-2524 (2010). 10.1016/j.bmcl.2010.02.098 Cited by (7) \| Cite \| Source
Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists (journal article) Evindar, Ghotas \| Satz, Alexander L. \| Bernier, Sylvie G. \| Kavarana, Malcolm J. \| Doyle, Elisabeth \| Lorusso, Jeanine \| Taghizadeh, Nazbeh \| Halley, Keith \| Hutchings, Amy \| Kelley, Michael S. \| ... \| Westlin, William F. Bioorganic & Medicinal Chemistry Letters, volume 19, issue 8, pages 2315-2319 (2009). 10.1016/j.bmcl.2009.02.073 Cited by (7) \| Cite \| Source
Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists (journal article) Evindar, Ghotas \| Bernier, Sylvie G. \| Kavarana, Malcolm J. \| Doyle, Elisabeth \| Lorusso, Jeanine \| Kelley, Michael S. \| Halley, Keith \| Hutchings, Amy \| Wright, Albion D. \| Saha, Ashis K. \| ... \| Westlin, William F. Bioorganic & Medicinal Chemistry Letters, volume 19, issue 2, pages 369-372 (2009). 10.1016/j.bmcl.2008.11.072 Cited by (13) \| Cite \| Source
Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity (patent) Saha, Ashis K. \| Kavarana, Malcolm J. \| Evindar, Ghotas \| Satz, Alexander L. \| Morgan, Barry Patent Number: 7241812 (2007) Cited by (1) \| Cite \| Source
Novel Triazole Based Inhibitors of Ras Farnesyl Transferase. (journal article) Saha, Ashis K. \| Liu, Li \| Simoneaux, Richard \| DeCorte, Bart \| Meyer, Christophe \| Skrzat, Stacy \| Breslin, Henry J. \| Kukla, Michael J. \| End, Dave W. ChemInform, volume 37, issue 11 (2006). 10.1002/chin.200611234 Cite \| Source
Novel triazole based inhibitors of Ras farnesyl transferase (journal article) Saha, Ashis K. \| Liu, Li \| Simoneaux, Richard \| DeCorte, Bart \| Meyer, Christophe \| Skrzat, Stacy \| Breslin, Henry J. \| Kukla, Michael J. \| End, Dave W. Bioorganic & Medicinal Chemistry Letters, volume 15, issue 24, pages 5407-5411 (2005). 10.1016/j.bmcl.2005.09.007 Cited by (24) \| Cite \| Source
Methods and compositions for modulating sphingosine-1-phosphate (s1p) receptor activity (patent) Saha, Ashis K. \| Kavarana, Malcolm J. \| Evindar, Ghotas \| Satz, Alexander L. \| Morgan, Barry Patent Number: 20060135786 (2005) Cited by (11) \| Cite \| Source
Novel β-(imidazol-4-yl)-β-amino acids: solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase type I (journal article) Saha, Ashis K. \| End, David W. Bioorganic & Medicinal Chemistry Letters, volume 15, issue 6, pages 1713-1719 (2005). 10.1016/j.bmcl.2005.01.042 Cited by (5) \| Cite \| Source
4-Methyl-1,2,4-triazol-3-yl heterocycle as an alternative to the 1-methylimidazol-5-yl moiety in the Farnesyltransferase inhibitor ZARNESTRA ™ (journal article) Angibaud, Patrick \| Saha, Ashis K. \| Bourdrez, Xavier \| End, David W. \| Freyne, Eddy \| Lezouret, Patricia \| Mannens, Geert \| Mevellec, Laurence \| Meyer, Christophe \| Pilatte, Isabelle \| ... \| Wouters, Walter Bioorganic & Medicinal Chemistry Letters, volume 13, issue 24, pages 4361-4364 (2003). 10.1016/j.bmcl.2003.09.043 Cited by (15) \| Cite \| Source
A Versatile and Inexpensive Apparatus for Rapid Parallel Synthesis on Solid Support: Description and Synthesis Illustration (journal article) Saha, Ashis K. \| Liu, Li \| Simoneaux, Richard L. Journal of Combinatorial Chemistry, volume 3, issue 2, pages 181-188 (2001). 10.1021/cc0000794 Cited by (6) \| Cite \| Source
Novel antifungals based on 4-substituted imidazole: solid-phase synthesis of substituted aryl sulfonamides towards optimization of in vitro activity (journal article) Saha, Ashis K. \| Liu, Li \| Marichal, Patrick \| Odds, Frank Bioorganic & Medicinal Chemistry Letters, volume 10, issue 24, pages 2735-2739 (2000). 10.1016/S0960-894X(00)00551-5 Cited by (22) \| Cite \| Source
Novel antifungals based on 4-substituted imidazole: A combinatorial chemistry approach to lead discovery and optimization (journal article) Saha, Ashis K \| Liu, Li \| Simoneaux, Richard L \| Kukla, Michael J \| Marichal, Patrick \| Odds, Frank Bioorganic & Medicinal Chemistry Letters, volume 10, issue 19, pages 2175-2178 (2000). 10.1016/S0960-894X(00)00445-5 Cited by (29) \| Cite \| Source