Kasper Lage

ScholarGPS® ID: 72720886915922

Affiliation

Massachusetts General Hospital, Boston, United States

Affiliation History

Field

Medicine

Discipline

Psychiatry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

8,425

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease (journal article) Zhu, Qiuyu Martin \| Hsu, Yu-Han H. \| Lassen, Frederik H. \| MacDonald, Bryan T. \| Stead, Stephanie \| Malolepsza, Edyta \| Kim, April \| Li, Taibo \| Mizoguchi, Taiji \| Schenone, Monica \| ... \| Lage, Kasper Communications Biology, volume 7, issue 1 (2024). 10.1038/s42003-023-05705-1 Cite \| Source
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders (journal article) Pintacuda, Greta \| Hsu, Yu-Han H. \| Tsafou, Kalliopi \| Li, Ka Wan \| Martín, Jacqueline M. \| Riseman, Jackson \| Biagini, Julia C. \| Ching, Joshua K.T. \| Mena, Daya \| Gonzalez-Lozano, Miguel A. \| ... \| Lage, Kasper Cell Genomics, volume 3, issue 3, pages 100250- (2023). 10.1016/j.xgen.2022.100250 Cited by (13) \| Cite \| Source
Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells (journal article) Dubonyte, Ugne \| Asenjo-Martinez, Andrea \| Werge, Thomas \| Lage, Kasper \| Kirkeby, Agnete Acta Neuropathologica Communications, volume 10, issue 1 (2022). 10.1186/s40478-022-01460-2 Cited by (5) \| Cite \| Source
Endothelial ARHGEF26 is an angiogenic factor promoting VEGF signalling (journal article) Zhu, Qiuyu Martin \| MacDonald, Bryan T \| Mizoguchi, Taiji \| Chaffin, Mark \| Leed, Alison \| Arduini, Alessandro \| Malolepsza, Edyta \| Lage, Kasper \| Kaushik, Virendar K \| Kathiresan, Sekar \| Ellinor, Patrick T Cardiovascular Research, volume 118, issue 13, pages 2833-2846 (2022). 10.1093/cvr/cvab344 Cited by (4) \| Cite \| Source
41. USING BRAIN CELL-TYPE-SPECIFIC INTERACTOMES OF PROTEINS ENCODED BY RISK GENES TO UNCOVER BIOLOGY UNDERLYING SCHIZOPHRENIA AND RELATED DISORDERS (journal article) Pintacuda, Greta \| Hsu, Yu-Han \| Biagini, Julia \| Martins, Nadine Fornelos \| Lage, Kasper European Neuropsychopharmacology, volume 63 (2022). 10.1016/j.euroneuro.2022.07.129 Cite \| Source
INTERACTION STUDIES OF RISK PROTEINS IN HUMAN INDUCED NEURONS REVEAL CONVERGENT BIOLOGY AND NOVEL MECHANISMS UNDERLYING AUTISM SPECTRUM DISORDERS (journal article) Lage, Kasper \| Pintacuda, Greta \| Hsu, Yu-Han \| Tsafou, Kalliopi \| Li, Ka-Wan \| Martin, Jacqueline \| Gonzalez-Lozano, Miguel \| Biagini, Julia \| Ching, Joshua \| Riseman, Jackson \| ... \| Eggan, Kevin European Neuropsychopharmacology, volume 63 (2022). 10.1016/j.euroneuro.2022.07.049 Cite \| Source
COMBINING PROTEOMICS WITH GENETICS TO ELUCIDATE THE MOLECULAR MECHANISMS UNDERLYING NEURODEVELOPMENTAL AND NEUROPSYCHIATRIC DISEASES IN HUMAN NEURONS (journal article) Pintacuda, Greta \| Hsu, Yu-Han \| Martín, Jacqueline M \| Ratanatharathorn, Andrew \| Maihofer, Adam X \| Chaby, Lauren \| Lasseter, Heather \| Haas, Magali \| Jeromin, Andreas \| Nievergelt, Caroline M \| ... \| Eggan, Kevin European Neuropsychopharmacology, volume 51 (2021). 10.1016/j.euroneuro.2021.07.071 Cite \| Source
Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction (journal article) Sun, Jiangming \| Wang, Yunpeng \| Folkersen, Lasse \| Borné, Yan \| Amlien, Inge \| Buil, Alfonso \| Orho-Melander, Marju \| Børglum, Anders D. \| Hougaard, David M. \| Lotta, Luca Andrea \| ... \| Lage, Kasper Nature Communications, volume 12, issue 1 (2021). 10.1038/s41467-021-25014-7 Cited by (10) \| Cite \| Source
Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility (journal article) Hartl, Christopher L. \| Ramaswami, Gokul \| Pembroke, William G. \| Muller, Sandrine \| Pintacuda, Greta \| Saha, Ashis \| Parsana, Princy \| Battle, Alexis \| Lage, Kasper \| Geschwind, Daniel H. Nature Neuroscience, volume 24, issue 9, pages 1313-1323 (2021). 10.1038/s41593-021-00887-5 Cited by (33) \| Cite \| Source
Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data (journal article) Pintacuda, Greta \| Lassen, Frederik H. \| Hsu, Yu-Han H. \| Kim, April \| Martín, Jacqueline M. \| Malolepsza, Edyta \| Lim, Justin K. \| Fornelos, Nadine \| Eggan, Kevin C. \| Lage, Kasper Nature Communications, volume 12, issue 1 (2021). 10.1038/s41467-021-22648-5 Cited by (12) \| Cite \| Source
Combining Proteomics With Genetics to Elucidate the Molecular Mechanisms Underlying Posttraumatic Stress Disorder in Human Neurons (journal article) Eggan, Kevin \| Pintacuda, Greta \| Tsafou, Kalliopi \| Hsu, Yu-Han \| Martin, Jacqueline \| Fornelos, Nadine \| Lasseter, Heather \| Chaby, Lauren \| Haas, Magali \| Jeromin, Andreas \| ... \| Lage, Kasper Biological Psychiatry, volume 89, issue 9, pages S11- (2021). 10.1016/j.biopsych.2021.02.048 Cite \| Source
Systematic auditing is essential to debiasing machine learning in biology (journal article) Eid, Fatma-Elzahraa \| Elmarakeby, Haitham A. \| Chan, Yujia Alina \| Fornelos, Nadine \| ElHefnawi, Mahmoud \| Van Allen, Eliezer M. \| Heath, Lenwood S. \| Lage, Kasper Communications Biology, volume 4, issue 1 (2021). 10.1038/s42003-021-01674-5 Cited by (14) \| Cite \| Source
Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML (journal article) Tothova, Zuzana \| Valton, Anne-Laure \| Gorelov, Rebecca A. \| Vallurupalli, Mounica \| Krill-Burger, John M. \| Holmes, Amie \| Landers, Catherine C. \| Haydu, J. Erika \| Malolepsza, Edyta \| Hartigan, Christina \| ... \| Ebert, Benjamin L. JCI Insight, volume 6, issue 3 (2021). 10.1172/jci.insight.142149 Cited by (45) \| Cite \| Source
Leadership (journal article) Bowdish, Dawn \| Desai, Tejal A. \| DePace, Angela \| Haswell, Elizabeth S. \| Baltrus, David \| García, Andrés J. \| Deans, Tara \| Lage, Kasper \| Wittkopp, Patricia Cell Systems, volume 12, issue 1, pages 1-4 (2021). 10.1016/j.cels.2020.12.004 Cited by (1) \| Cite \| Source
Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants (journal article) Iqbal, Sumaiya \| Pérez-Palma, Eduardo \| Jespersen, Jakob B. \| May, Patrick \| Hoksza, David \| Heyne, Henrike O. \| Ahmed, Shehab S. \| Rifat, Zaara T. \| Rahman, M. Sohel \| Lage, Kasper \| ... \| Lal, Dennis Proceedings of the National Academy of Sciences, volume 117, issue 45, pages 28201-28211 (2020). 10.1073/pnas.2002660117 Cited by (53) \| Cite \| Source
TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci (journal article) Davis, Erica E \| Balasubramanian, Ravikumar \| Kupchinsky, Zachary A \| Keefe, David L \| Plummer, Lacey \| Khan, Kamal \| Meczekalski, Blazej \| Heath, Karen E \| Lopez-Gonzalez, Vanesa \| Ballesta-Martinez, Mary J \| ... \| Katsanis, Nicholas Human Molecular Genetics, volume 29, issue 14, pages 2435-2450 (2020). 10.1093/hmg/ddaa120 Cited by (12) \| Cite \| Source
Prediction of cancer driver genes through network-based moment propagation of mutation scores (journal article) Gumpinger, Anja C \| Lage, Kasper \| Horn, Heiko \| Borgwardt, Karsten Bioinformatics, volume 36, issue Supplement_1, pages i508-i515 (2020). 10.1093/bioinformatics/btaa452 Cited by (18) \| Cite \| Source
Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data (journal article) Fernández-Tajes, Juan \| Gaulton, Kyle J. \| van de Bunt, Martijn \| Torres, Jason \| Thurner, Matthias \| Mahajan, Anubha \| Gloyn, Anna L. \| Lage, Kasper \| McCarthy, Mark I. Genome Medicine, volume 11, issue 1 (2019). 10.1186/s13073-019-0628-8 Cited by (25) \| Cite \| Source
FUNCTIONAL INTERPRETATION OF GENETIC DATA IN PSYCHIATRIC DISEASES USING HUMAN NEURONAL PROTEIN-PROTEIN INTERACTION NETWORKS (journal article) Lage, Kasper European Neuropsychopharmacology, volume 29 (2019). 10.1016/j.euroneuro.2019.07.126 Cite \| Source
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology (journal article) Tanigawa, Yosuke \| Li, Jiehan \| Justesen, Johanne M. \| Horn, Heiko \| Aguirre, Matthew \| DeBoever, Christopher \| Chang, Chris \| Narasimhan, Balasubramanian \| Lage, Kasper \| Hastie, Trevor \| ... \| Rivas, Manuel A. Nature Communications, volume 10, issue 1 (2019). 10.1038/s41467-019-11953-9 Cited by (36) \| Cite \| Source